Sebastian Mathea

Also affiliated with Structural Genomics Consortium, Institute of Molecular Biology

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 15 papers. Top paper: “Structure of LRRK2 in Parkinson’s disease and model for microtubule interaction”.

Structure of LRRK2 in Parkinson’s disease and model for microtubule interaction

Nature(2020)10.1038/s41586-020-2673-2

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0DataRank · unranked

247 citations

John Salogiannis, Sebastian Mathea, David Snead, Indrajit Lahiri, Mariusz Matyszewski +9 more

Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases

Molecular Cell(2020)10.1016/j.molcel.2020.06.018

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0DataRank · unranked

104 citations

Sebastian Mathea, Hanna Karvonen, Ketan Malhotra, Deep Chatterjee, Wilhelmiina Niininen +10 more

Modulating Androgen Receptor-Driven Transcription in Prostate Cancer with Selective CDK9 Inhibitors

Cell chemical biology(2020)10.1016/j.chembiol.2020.10.001

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0DataRank · unranked

81 citations

Shelby K. Doyle, David B. Freeman, Christina Lee, Becky Leifer, Sajjeev Jagannathan +34 more

Nucleotide Binding, Evolutionary Insights, and Interaction Partners of the Pseudokinase Unc-51-like Kinase 4

Structure(2020)10.1016/j.str.2020.07.016

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0DataRank · unranked

39 citations

Deep Chatterjee, Sebastian Mathea, Safal Shrestha, Jonathan St‐Germain, Manipa Saha +5 more

Parkinson’s Disease-linked LRRK2 structure and model for microtubule interaction

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.06.895367

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0DataRank · unranked

21 citations

John Salogiannis, Sebastian Mathea, David Snead, Indrajit Lahiri, Oscar Donosa +8 more

Nucleotide binding, evolutionary insights and interaction partners of the pseudokinase Unc-51-like kinase 4

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.18.159293

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0DataRank · unranked

2 citations

Deep Chatterjee, Sebastian Mathea, Safal Shrestha, Jonathan St‐Germain, Manipa Saha +5 more

Conformation and Dynamics of the Kinase Domain Drive Subcellular Location and Activation of LRRK2.

Research Square(2020)10.21203/rs.3.rs-59611/v1

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0DataRank · unranked

0 citations

Jui‐Hung Weng, Phillip C. Aoto, Daniela Boassa, Steven Silletti, Sebastian Mathea +7 more

Conformation and dynamics of the kinase domain drive subcellular location and activation of LRRK2

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2100844118

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0DataRank · unranked

77 citations

Jui‐Hung Weng, Phillip C. Aoto, Daniela Boassa, Sebastian Mathea, Steve Silletti +8 more

Identification of Pyrimidine-Based Lead Compounds for Understudied Kinases Implicated in Driving Neurodegeneration

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.1c00440

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0DataRank · unranked

33 citations

Joel K. Annor‐Gyamfi, Carrow I. Wells, Julie E. Pickett, Verena Dederer, Franziska Preuß +3 more

Two helices control the dynamic crosstalk between the catalytic domains of LRRK2

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.29.462278

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0DataRank · unranked

1 citations

Phillip C. Aoto, Robin Lorenz, Jian Wu, Sven H. Schmidt, Jascha T. Manschwetus +6 more

Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases

The FASEB Journal(2021)10.1096/fasebj.2021.35.s1.02446

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0DataRank · unranked

0 citations

Sebastian Mathea, Hanna Karvonen, Ketan Malhotra, Deep Chatterjee, Wilhelmiina Niininen +10 more

LRRK2 dynamics analysis identifies allosteric control of the crosstalk between its catalytic domains

PLoS Biology(2022)10.1371/journal.pbio.3001427

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0DataRank · unranked

27 citations

Phillip C. Aoto, Robin Lorenz, Jian Wu, Sven H. Schmidt, Jascha T. Manschwetus +8 more

Inhibition of Parkinson’s disease–related LRRK2 by type I and type II kinase inhibitors: Activity and structures

Science Advances(2023)10.1126/sciadv.adk6191

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0DataRank · unranked

48 citations

Amalia Villagran Suarez, Verena Dederer, Deep Chatterjee, Jaime Alegrio Louro, Stefan Knapp +3 more

Structure of LRRK1 and mechanisms of autoinhibition and activation

Nature Structural & Molecular Biology(2023)10.1038/s41594-023-01109-1

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0DataRank · unranked

13 citations

Andrea M. Dickey, Yu Xuan Lin, Robert G. Abrisch, Sebastian Mathea, Deep Chatterjee +6 more

Type-II kinase inhibitors that target Parkinson’s Disease-associated LRRK2

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.17.613365

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0DataRank · unranked

4 citations

Katherine J. Surridge, Marta Sanz Murillo, Verena Dederer, Andreas Krämer, Martin P. Schwalm +8 more