George P. Lisi

Also affiliated with Brown University, Yale University

Biochemistry, Genetics and Molecular BiologyImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 33 papers. Top paper: “High-throughput prediction of protein conformational distributions with subsampled AlphaFold2”.

High-throughput prediction of protein conformational distributions with subsampled AlphaFold2

Nature Communications(2024)10.1038/s41467-024-46715-9

N/A

0.797DataRank · unranked

202 citations

Jennifer Y. Cui, David C. Dalgarno, George P. Lisi, Brenda M. Rubenstein, Gabriel Monteiro da Silva

Principles of target DNA cleavage and the role of Mg2+ in the catalysis of CRISPR–Cas9

Nature Catalysis(2022)10.1038/s41929-022-00848-6

N/A

0.659DataRank · unranked

80 citations

Kyle W. East, Jonas M. Binz, Rohaine V. Hsu, Mohd Ahsan, Pablo R. Arantes +6 more

Enhanced specificity mutations perturb allosteric signaling in CRISPR-Cas9

eLife(2021)10.7554/elife.73601

N/A

0.639DataRank · unranked

70 citations

Kyle W East, Uriel N Morzan, Pablo R Arantes, Victor S Batista, George P. Lisi +2 more

Mapping N- to C-terminal allosteric coupling through disruption of a putative CD74 activation site in D-dopachrome tautomerase

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.104729

N/A

0.461DataRank · unranked

9 citations

Vinnie Widjaja, Gregory W. Kyro, Brandon Allen, Pragnya Das, Varsha Prahaladan +5 more

Disruption of electrostatic contacts in the HNH nuclease from a thermophilic Cas9 rewires allosteric motions and enhances high-temperature DNA cleavage

The Journal of Chemical Physics(2022)10.1063/5.0128815

N/A

0.434DataRank · unranked

17 citations

Carmelissa Norbrun, Jinping Luo, Chinmai Pindi, Souvik Sinha, Alexandra M. D’Ordine +4 more

Structural and dynamic impacts of single-atom disruptions to guide RNA interactions within the recognition lobe of Geobacillus stearothermophilus Cas9

eLife(2024)10.7554/elife.99275

N/A

0.269DataRank · unranked

5 citations

Alexa L Knight, Alexandra M. D’Ordine, Chinmai Pindi, Zhi-Qiang Fan, Jinping Luo +4 more

High-Fidelity, Hyper-Accurate, and Evolved Mutants Rewire Atomic Level Communication in CRISPR-Cas9

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.25.554853

N/A

0.208DataRank · unranked

3 citations

Souvik Sinha, Mohd Ahsan, Alexandra M. D’Ordine, G. Jogl, Giulia Palermo +2 more

A Cryptic Binding Pocket Regulates the Metal-Dependent Activity of Cas9

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.25.672025

N/A

0.199DataRank · unranked

2 citations

Aakash Saha, Delisa Ramos, Isabel Strohkendl, Alexa L. Knight, Erin Skeens +4 more

Atomistic modulation of MIF ‐2 structure, catalysis, and biological signaling via cysteine residues and a small molecule, Ebselen

Protein Science(2025)10.1002/pro.70344

N/A

0.104DataRank · unranked

1 citations

Sirena M. D'Orazio, Pragnya Das, Divya Rajendran, Xander Takada, Yuanjun Shi +8 more

Structural and dynamic impacts of single-atom disruptions to guide RNA interactions within the recognition lobe of Geobacillus stearothermophilus Cas9

eLife(2025)10.7554/elife.99275.4

N/A

0.104DataRank · unranked

1 citations

Alexa L Knight, Alexandra M D'Ordine, Chinmai Pindi, Zhi-Qiang Fan, Jinping Luo +4 more

Ligand-induced conformational changes enable intersubunit communications in D-dopachrome tautomerase

Biophysical Journal(2023)10.1016/j.bpj.2023.02.019

N/A

0DataRank · unranked

14 citations

Emily Chen, Vanessa M. Rangel, Mandeep Singh, Liang Xue, George P. Lisi +2 more

Substrate-independent activation pathways of the CRISPR-Cas9 HNH nuclease

Biophysical Journal(2023)10.1016/j.bpj.2023.11.005

N/A

0DataRank · unranked

6 citations

Federica Maschietto, Tianyin Qiu, Pablo R. Arantes, Erin Skeens, Giulia Palermo +3 more

Temperature as a modulator of allosteric motions and crosstalk in mesophilic and thermophilic enzymes

Frontiers in Molecular Biosciences(2023)10.3389/fmolb.2023.1281062

N/A

0DataRank · unranked

8 citations

Vinnie Widjaja, George P. Lisi, Alexa L. Knight

The Many (Inter)faces of Anti-CRISPRs: Modulation of CRISPR-Cas Structure and Dynamics by Mechanistically Diverse Inhibitors

Biomolecules(2023)10.3390/biom13020264

N/A

0DataRank · unranked

3 citations

George P. Lisi, Helen B Belato

Valproate-coenzyme A conjugate blocks opening of receptor binding domains in the spike trimer of SARS-CoV-2 through an allosteric mechanism

Computational and Structural Biotechnology Journal(2023)10.1016/j.csbj.2023.01.014

N/A

0DataRank · unranked

5 citations

Tianyin Qiu, Jimin Wang, Yuanjun Shi, Brandon Allen, George P. Lisi +3 more

Predicting Relative Populations of Protein Conformations without a Physics Engine Using AlphaFold2

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.25.550545

N/A

0DataRank · unranked

11 citations

Jennifer Y. Cui, David C. Dalgarno, George P. Lisi, Brenda M. Rubenstein, Gabriel Monteiro da Silva

Redox-dependent plasticity of oxMIF facilitates its interaction with CD74 and therapeutic antibodies

Redox Biology(2024)10.1016/j.redox.2024.103264

N/A

0DataRank · unranked

8 citations

Erin Skeens, Alexander Schinagl, Maroua Ferhat, Irina Mirkina, Julia Mayer +4 more

Structural and Dynamic Impacts of Single-atom Disruptions to Guide RNA Interactions within the Recognition Lobe of Geobacillus stearothermophilus Cas9

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.26.591382

N/A

0DataRank · unranked

0 citations

Alexa L Knight, Alexandra M D'Ordine, Chinmai Pindi, Zhi-Qiang Fan, Jinping Luo +4 more

Structural, biological, and biomedical implications of mRNA interactions with the master regulator HuR

NAR Molecular Medicine(2025)10.1093/narmme/ugaf002

N/A

0DataRank · unranked

4 citations

Andrew Farinha, Alan Morrison, George P. Lisi, Madeline E Clark

Dynamic and structural insights into allosteric regulation on MKP5 a dual-specificity phosphatase

Nature Communications(2025)10.1038/s41467-025-62150-w

N/A

0DataRank · unranked

2 citations

Federica Maschietto, R. Manjula, Shanelle R. Shillingford, James H. Murphy, Elias Lolis +4 more

Structural and Dynamic Impacts of Single-atom Disruptions to Guide RNA Interactions within the Recognition Lobe of Geobacillus stearothermophilus Cas9

eLife(2025)10.7554/elife.99275.2

N/A

0DataRank · unranked

0 citations

Alexa L Knight, Alexandra M. D’Ordine, Chinmai Pindi, Zhi-Qiang Fan, Jinping Luo +4 more

Allosteric Modulation of MIF-2 Structure, Catalysis, and Biological Signaling via Cysteine Residues and a Small Molecule, Ebselen

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.15.654344

N/A

0DataRank · unranked

0 citations

Sirena M. D’Orazio, Pragnya Das, Xander Takada, Divya Rajendran, Yuanjun Shi +7 more

Regulation of MIF Enzymatic Activity by an Allosteric Site at the Central Solvent Channel

Cell chemical biology(2020)10.1016/j.chembiol.2020.05.001

N/A

0DataRank · unranked

34 citations

Leepakshi Khurana, Anthony Ma, Erin Skeens, Krystle Reiss, Víctor S. Batista +3 more

Design Rules for Expanding PAM Compatibility in CRISPR-Cas9 from the VQR, VRER and EQR variants

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.03.673821

N/A

0DataRank · unranked

0 citations

Chinmai Pindi, George P. Lisi, Uriel N. Morzan, Giulia Palermo, Francisco H. Vieya

A structurally preserved allosteric site in the MIF superfamily affects enzymatic activity and CD74 activation in D-dopachrome tautomerase

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.101061

N/A

0DataRank · unranked

25 citations

Krystle Reiss, Dilip Shah, R. Manjula, Brandon Allen, Eva Murphy +6 more

Analysis of coordinated NMR chemical shifts to map allosteric regulatory networks in proteins

Methods(2022)10.1016/j.ymeth.2022.12.002

N/A

0DataRank · unranked

17 citations

George P. Lisi, Erin Skeens

Structural Insights into Binding of Remdesivir Triphosphate within the Replication–Transcription Complex of SARS-CoV-2

Biochemistry(2022)10.1021/acs.biochem.2c00341

N/A

0DataRank · unranked

16 citations

Yuanjun Shi, Krystle Reiss, Federica Maschietto, Elias Lolis, William H. Konigsberg +3 more

How to correct relative voxel scale factors for calculations of vector-difference Fourier maps in cryo-EM

Journal of Structural Biology(2022)10.1016/j.jsb.2022.107902

N/A

0DataRank · unranked

13 citations

Jinchan Liu, Christopher J. Gisriel, Shenping Wu, Federica Maschietto, David A. Flesher +6 more

Insights into Binding of Single-Stranded Viral RNA Template to the Replication–Transcription Complex of SARS-CoV-2 for the Priming Reaction from Molecular Dynamics Simulations

Biochemistry(2022)10.1021/acs.biochem.1c00755

N/A

0DataRank · unranked

15 citations

Yuanjun Shi, Krystle Reiss, Brandon Allen, Federica Maschietto, Elias Lolis +4 more

Identification and mechanistic basis of non-ACE2 blocking neutralizing antibodies from COVID-19 patients with deep RNA sequencing and molecular dynamics simulations

Frontiers in Molecular Biosciences(2022)10.3389/fmolb.2022.1080964

N/A

0DataRank · unranked

4 citations

Kyle W. East, Yuanjun Shi, Jinchan Liu, Federica Maschietto, Alfred Ayala +11 more

Editorial: Structural and Dynamic Aspects of Protein Function and Allostery

Frontiers in Molecular Biosciences(2022)10.3389/fmolb.2022.876499

N/A

0DataRank · unranked

0 citations

Ivan Rivalta, Vincenzo Venditti, George P. Lisi

Unique structural and dynamic properties of the HNH nuclease in mesophilic and thermophilic Cas9 revealed by NMR

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.l7446

N/A

0DataRank · unranked

0 citations

Alexandra M. D’Ordine, G. Jogl, George P. Lisi, Helen B Belato

Twisting and swiveling domain motions in Cas9 to recognize target DNA duplexes, make double-strand breaks, and release cleaved duplexes

Frontiers in Molecular Biosciences(2023)10.3389/fmolb.2022.1072733

N/A

0DataRank · unranked

22 citations

Pablo R. Arantes, Mohd Ahsan, Souvik Sinha, Gregory W. Kyro, Federica Maschietto +6 more