Courtney C. Aldrich

Also affiliated with University of Minnesota System

Arts and HumanitiesMedicineBiochemistry, Genetics and Molecular BiologyDecision SciencesSocial Sciences

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 43 papers. Top paper: “PROTAC antibiotics: the time is now”.

PROTAC antibiotics: the time is now

Expert Opinion on Drug Discovery(2023)10.1080/17460441.2023.2178413

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0.434DataRank · unranked

17 citations

Courtney C. Aldrich, Mei‐Lin Go, Thomas Dick, Jickky Palmae Sarathy

Biosynthesis, Mechanism of Action, and Inhibition of the Enterotoxin Tilimycin Produced by the Opportunistic Pathogen Klebsiella oxytoca

ACS Infectious Diseases(2020)10.1021/acsinfecdis.0c00326

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0DataRank · unranked

36 citations

Dale F. Kreitler, Valeria Guidolin, Alexander K. Hurben, Eric J. Drake, Peter W. Villalta +4 more

Development of small-molecule inhibitors of fatty acyl-AMP and fatty acyl-CoA ligases in Mycobacterium tuberculosis

European Journal of Medicinal Chemistry(2020)10.1016/j.ejmech.2020.112408

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0DataRank · unranked

30 citations

Kimberly D. Grimes, Paul A. Sibbald, Peng Fu, Helena I. Boshoff, Daniel J. Wilson +2 more

High-Throughput Screening Yields Allosteric Inhibitors of Leaky RyRs for Therapeutic Development

Biophysical Journal(2020)10.1016/j.bpj.2019.11.3095

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0DataRank · unranked

0 citations

Gabrielle M. Evans, Kaja Rožman, Jacob Schwarz, Michael C. Wold, Marzena Baran +5 more

Blocking Bacterial Naphthohydroquinone Oxidation and ADP-Ribosylation Improves Activity of Rifamycins against Mycobacterium abscessus

Antimicrobial Agents and Chemotherapy(2021)10.1128/aac.00978-21

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0DataRank · unranked

31 citations

Tian Lan, Philipp Krastel, Marissa Lindman, Matthew Zimmerman, Hsin‐Pin Ho +6 more

Reinvestigation of the structure-activity relationships of isoniazid

Tuberculosis(2021)10.1016/j.tube.2021.102100

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0DataRank · unranked

15 citations

Helena I. Boshoff, Yudi Rusman, Wassihun Wedajo Aragaw, Christine Salomon, Thomas Dick +2 more

Cardiac ryanodine receptor N-terminal region biosensors identify novel inhibitors via FRET-based high-throughput screening

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.101412

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0DataRank · unranked

4 citations

Daniel P. Singh, Christopher Y. Ko, Roman Nikolaienko, Siobhan M. Wong King Yuen, Jacob Schwarz +12 more

Cardiac RyR N-terminal region biosensors for FRET-based high-throughput screening

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.07.430153

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0DataRank · unranked

0 citations

Siobhan M. Wong King Yuen, Jacob Schwarz, Levy M. Treinen, Ching‐Chieh Tung, Robyn T. Rebbeck +7 more

High-Throughput Screening and Drug Development to Fix RyR Pathology

Biophysical Journal(2021)10.1016/j.bpj.2020.11.1089

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0DataRank · unranked

0 citations

Kaja Rožman, Gabrielle M. Evans, Jacob Schwarz, Marzena Baran, Courtney C. Aldrich +4 more

Redesign of Rifamycin Antibiotics to Overcome ADP‐Ribosylation‐Mediated Resistance

Angewandte Chemie International Edition(2022)10.1002/anie.202211498

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0DataRank · unranked

23 citations

Uday S. Ganapathy, Sachin Sharma, Yong‐Mo Ahn, Matthew Zimmerman, Vadim Molodtsov +8 more

Synthesis and biological evaluation of orally active prodrugs and analogs of para-aminosalicylic acid (PAS)

European Journal of Medicinal Chemistry(2022)10.1016/j.ejmech.2022.114201

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0DataRank · unranked

14 citations

Michael D. Howe, Matthew Zimmerman, Helena I. Boshoff, Sachin Sharma, Brianna Remache +6 more

New N-aryl-N-alkyl-thiophene-2-carboxamide compound enhances intracellular Ca2+ dynamics by increasing SERCA2a Ca2+ pumping

Biophysical Journal(2022)10.1016/j.bpj.2022.12.002

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0DataRank · unranked

9 citations

Elisa Bovo, Samantha L. Yuen, Levy M. Treinen, Kaja Berg, Courtney C. Aldrich +4 more

Parameterization and Application of the General Amber Force Field to Model Fluoro Substituted Furanose Moieties and Nucleosides

Molecules(2022)10.3390/molecules27092616

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0DataRank · unranked

3 citations

Courtney C. Aldrich, David M. Ferguson, Diego E. Escalante

Structure activity relationship of pyrazinoic acid analogs as potential antimycobacterial agents

Bioorganic & Medicinal Chemistry(2022)10.1016/j.bmc.2022.117046

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0DataRank · unranked

3 citations

Wassihun Wedajo Aragaw, Malcolm S. Cole, Gorakhnath R. Jachak, Priya Ragunathan, Sachin Sharma +5 more

Structural and Mechanistic Insights into Mycobacterium abscessus Aspartate Decarboxylase PanD and a Pyrazinoic Acid-Derived Inhibitor

ACS Infectious Diseases(2022)10.1021/acsinfecdis.2c00133

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0DataRank · unranked

7 citations

Chen Yen Leow, Amaravadhi Harikishore, Joon Shin, Malcolm S. Cole, Wassihun Wedajo Aragaw +6 more

Broad Tricyclic Ring Inhibitors Block SARS-CoV-2 Spike Function Required for Viral Entry

ACS Infectious Diseases(2022)10.1021/acsinfecdis.1c00658

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0DataRank · unranked

7 citations

Anthony R. Braun, Héctor Cervera, Danielle Carlson, Shilei Ding, Carolyn N. Paulson +6 more

Drugging the microbiome: targeting small microbiome molecules

Current Opinion in Microbiology(2022)10.1016/j.mib.2022.102234

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0DataRank · unranked

3 citations

Pooja Hegde, Subhankar Panda, Moyosore O. Orimoloye, Courtney C. Aldrich, Sachin Sharma

FRET assays for RyR-targeted drug discovery platforms

Biophysical Journal(2022)10.1016/j.bpj.2021.11.1857

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0DataRank · unranked

0 citations

Kaja Berg, Gabrielle M. Evans, Jacob Schwarz, Jake R. Trask, Lindsey M. McGurran +5 more

Two‐way regulation of protein expression for identification and validation of on‐target inhibitors of Mycobacterium tuberculosis

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.l7723

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0DataRank · unranked

0 citations

Curtis A. Engelhart, Esther Perez‐Herran, Divya Tiwari, Wei Li, Katherine A. Abrahams +9 more

Biotin-dependent cell envelope remodelling is required for Mycobacterium abscessus survival in lung infection

Nature Microbiology(2023)10.1038/s41564-022-01307-5

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0DataRank · unranked

30 citations

Kerry McGowen, Qiang Liu, Chidiebere Akusobi, David C. Young, Jacob A. Mayfield +7 more

Fluorescence lifetime FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulators

Scientific Reports(2023)10.1038/s41598-023-37704-x

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0DataRank · unranked

18 citations

Samantha L. Yuen, Andrew R. Thompson, Lauren N. Roelike, Robyn T. Rebbeck, Philip A. Bidwell +4 more

ADP-ribosylation-resistant rifabutin analogs show improved bactericidal activity against drug-tolerant M. abscessus in caseum surrogate

Antimicrobial Agents and Chemotherapy(2023)10.1128/aac.00381-23

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0DataRank · unranked

15 citations

Uday S. Ganapathy, Tian Lan, Paulina Osiecki, Jansy P. Sarathy, Véronique Dartois +3 more

Blocking ADP-ribosylation expands the anti-mycobacterial spectrum of rifamycins

Microbiology Spectrum(2023)10.1128/spectrum.01900-23

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0DataRank · unranked

9 citations

Tian Lan, Véronique Dartois, Courtney C. Aldrich, Thomas Dick, Uday S. Ganapathy

Metabolically distinct roles of NAD synthetase and NAD kinase define the essentiality of NAD and NADP in Mycobacterium tuberculosis

mBio(2023)10.1128/mbio.00340-23

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10 citations

Travis Hartman, Tiago Beites, Jeehyun Kim, Hyungjin Eoh, Curtis A. Engelhart +7 more

SAR study of piperidine derivatives as inhibitors of 1,4-dihydroxy-2-naphthoate isoprenyltransferase (MenA) from Mycobacterium tuberculosis

European Journal of Medicinal Chemistry(2023)10.1016/j.ejmech.2023.115125

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0DataRank · unranked

7 citations

Pooja Hegde, Venugopal Pujari, Marzena Brinkmann, David Z. Wilkins, Tanya Parish +3 more

FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulators

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.22.529557

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0DataRank · unranked

0 citations

Samantha L. Yuen, Andrew R. Thompson, Lauren N. Roelike, Robyn T. Rebbeck, Philip A. Bidwell +4 more

FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulators

Research Square(2023)10.21203/rs.3.rs-2596384/v1

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0DataRank · unranked

0 citations

Samantha L. Yuen, Andrew R. Thompson, Lauren N. Roelike, Robyn T. Rebbeck, Phillip A. Bidwell +4 more

Mycobacterial biotin synthases require an auxiliary protein to convert dethiobiotin into biotin

Nature Communications(2024)10.1038/s41467-024-48448-1

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0DataRank · unranked

9 citations

Peng Ge, Laure Botella, Sae Woong Park, Ha-Na Lee, Natalie Thornton +7 more

Central nervous system distributional kinetics of selected histone deacetylase inhibitors

Journal of Pharmacology and Experimental Therapeutics(2024)10.1124/jpet.124.002170

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0DataRank · unranked

6 citations

Ju‐Hee Oh, Wenjuan Zhang, Courtney C. Aldrich, Rachael W. Sirianni, William F. Elmquist +1 more

Pharmacokinetics of Panobinostat: Interspecies Difference in Metabolic Stability

Journal of Pharmacology and Experimental Therapeutics(2024)10.1124/jpet.123.002051

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0DataRank · unranked

2 citations

Ju‐Hee Oh, Wenjuan Zhang, Courtney C. Aldrich, Rachael W. Sirianni, William F. Elmquist +1 more

Mechanism of the Dual Action Self-Potentiating Antitubercular Drug Morphazinamide

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.10.08.617272

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0DataRank · unranked

2 citations

Taylor Crooks, Michael D. Howe, Thanh‐Sang Vo, Ziyi Jia, Pooja Hegde +4 more

Small-molecule allosteric modulators of SERCA2a for pharmaceutical therapy of heart failure

Biophysical Journal(2024)10.1016/j.bpj.2023.11.2087

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0DataRank · unranked

0 citations

Samantha L. Yuen, Elisa Bovo, Marzena Baran, Andrew R. Thompson, Robyn T. Rebbeck +4 more

Calcium channel-targeted modulators identified by FRET-based high-throughput screening

Biophysical Journal(2024)10.1016/j.bpj.2023.11.2777

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0DataRank · unranked

0 citations

Benjamin D. Van Setters, Marzena Brinkmann, Andrew R. Thompson, Courtney C. Aldrich, Donald M. Bers +3 more

Next-generation rifamycins for the treatment of mycobacterial infections

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2423842122

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0DataRank · unranked

13 citations

Tian Lan, Uday S. Ganapathy, Chui Fann Wong, Jickky Palmae Sarathy, Diana C. Jimenez +24 more

Large-scale high-throughput screen for cardiac ryanodine receptor targeted therapeutics

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110951

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0DataRank · unranked

1 citations

Elisa Bovo, Jonathan Solberg, Marzena Brinkmann, Levy M. Treinen, Andrew R. Thompson +9 more

Mechanism of the dual action self-potentiating antitubercular drug morphazinamide

PNAS Nexus(2025)10.1093/pnasnexus/pgaf242

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0DataRank · unranked

2 citations

Taylor Crooks, Michael D. Howe, Stephanie P. Vo, Ziyi Jia, Pooja Hegde +4 more

Validating Conditionally Essential Targets: Discovery of the First Orally Effective Biotin Inhibitor against Mycobacterium Tuberculosis

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.24.678246

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0DataRank · unranked

2 citations

Joshua B. Wallach, Yahani P. Jayasinghe, Mark R. Sullivan, Julianna Proietto, Suyapa Rodriguez +14 more

Metabolically Stable Adenylation Inhibitors of Biotin Protein Ligase as Antibacterial Agents

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.4c02299

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0DataRank · unranked

0 citations

Curtis A. Engelhart, Joshua B. Wallach, Divya Tiwari, Peng Ge, Adhar C. Manna +14 more

BPS2025 - Calcium channel and transporter targeted modulators identified by FRET-based high-throughput screening

Biophysical Journal(2025)10.1016/j.bpj.2024.11.648

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0DataRank · unranked

0 citations

Samantha L. Yuen, Michael E. Fealey, Marzena Brinkmann, Benjamin D. Van Setters, Andrew R. Thompson +5 more

BPS2025 - SERCA2a-targeted drugs for treatment of heart failure: Medicinal chemistry development of a compound identified via high-throughput screening

Biophysical Journal(2025)10.1016/j.bpj.2024.11.1614

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0DataRank · unranked

0 citations

Marzena Brinkmann, Samantha L. Yuen, Tien Yin Wong, Kaja Berg, Rǎzvan L. Cornea +4 more

Mycobactin and clofazimine activity are negatively correlated in mycobacteria

Frontiers in Microbiology(2025)10.3389/fmicb.2025.1539139

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0DataRank · unranked

0 citations

Christopher R. Covey, Matthew J. Reichlen, Anushila Chatterjee, Breck A. Duerkop, Surendra Dawadi +3 more

The Biotin Biosynthetic Pathway in Mycobacterium tuberculosis is a Validated Target for the Development of Antibacterial Agents

Current Medicinal Chemistry(2020)10.2174/0929867326666190119161551

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0DataRank · unranked

15 citations

Neeraj K. Mishra, Courtney C. Aldrich, Matthew R. Bockman

Development of activators for SERCA2a for heart failure treatments

European Journal of Medicinal Chemistry(2025)10.1016/j.ejmech.2025.118408

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0DataRank · unranked

0 citations

Tsung-Yun Wong, Osha Roopnarine, Samantha L. Yuen, Kaja Berg, Rǎzvan L. Cornea +4 more