Klaus Ley

Also affiliated with Augusta University, La Jolla Bioengineering Institute

MedicineImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 4%percentile

0.869Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Combined protein and transcript single-cell RNA sequencing in human peripheral blood mononuclear cells

BMC Biology(2022)10.1186/s12915-022-01382-4

Top 23%

0.869DataRank

Top 23%35 citations

Ryosuke Saigusa, Rishab Gulati, Sujit Silas Armstrong Suthahar, Vasantika Suryawanshi, Ahmad Alimadadi +23 more

Papers

Driven by 60 papers — median percentile 77. Top paper: “Combined protein and transcript single-cell RNA sequencing in human peripheral blood mononuclear cells”.

Combined protein and transcript single-cell RNA sequencing in human peripheral blood mononuclear cells

BMC Biology(2022)10.1186/s12915-022-01382-4

Top 23%

0.869DataRank

Top 23%35 citations

Ryosuke Saigusa, Rishab Gulati, Sujit Silas Armstrong Suthahar, Vasantika Suryawanshi, Ahmad Alimadadi +23 more

Single-cell profiling of CD11c+ B cells in atherosclerosis

Frontiers in Immunology(2024)10.3389/fimmu.2023.1296668

N/A

0.741DataRank · unranked

22 citations

Prasad Srikakulapu, Brett Ransegnola, Melissa A. Marshall, Yanal Ghosheh, Rishab Gulati +6 more

Leaking chemokines confuse neutrophils

Journal of Clinical Investigation(2020)10.1172/jci136259

N/A

0DataRank · unranked

15 citations

Klaus Ley, Alex Márki

CITE-Seq Hits Vascular Medicine

Clinical Chemistry(2020)10.1093/clinchem/hvaa016

N/A

0DataRank · unranked

9 citations

Klaus Ley, Ryosuke Saigusa

Epsin-mediated degradation of IP3R1 fuels atherosclerosis

Nature Communications(2020)10.1038/s41467-020-17848-4

N/A

0DataRank · unranked

44 citations

Yang Lee, Kui Cui, Ming He, Beibei Wang, Sudarshan Bhattacharjee +25 more

Opportunities for an atherosclerosis vaccine: From mice to humans

Vaccine(2020)10.1016/j.vaccine.2019.12.039

N/A

0DataRank · unranked

29 citations

Amal J. Ali, Kouji Kobiyama, Yanal Ghosheh, Klaus Ley, Payel Roy

Super-STORM: Molecular Modeling to Achieve Single-molecule Localization with STORM Microscopy

STAR Protocols(2020)10.1016/j.xpro.2019.100012

N/A

0DataRank · unranked

3 citations

Zbigniew Mikulski, Sara McArdle, Prithu Sundd, Klaus Ley, Zhichao Fan

Integrated scRNA-seq analysis identifies conserved transcriptomic features of mononuclear phagocytes in mouse and human atherosclerosis

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.09.417535

N/A

0DataRank · unranked

8 citations

Florian Erhard, Tobias Weinberger, Christian Schulz, Klaus Ley, Antoine‐Emmanuel Saliba +2 more

How the immune system shapes atherosclerosis: roles of innate and adaptive immunity

Nature reviews. Immunology(2021)10.1038/s41577-021-00584-1

N/A

0DataRank · unranked

546 citations

Marco Orecchioni, Klaus Ley, Payel Roy

Normalization of cholesterol metabolism in spinal microglia alleviates neuropathic pain

The Journal of Experimental Medicine(2021)10.1084/jem.20202059

N/A

0DataRank · unranked

104 citations

Soo‐Ho Choi, Luciano dos Santos Aggum Capettini, Yining Xia, Ayelet Gonen, Colin Agatisa-Boyle +16 more

CD45 pre-exclusion from the tips of T cell microvilli prior to antigen recognition

Nature Communications(2021)10.1038/s41467-021-23792-8

N/A

0DataRank · unranked

75 citations

Lai Wen, Amnon Altman, Klaus Ley, Yunmin Jung

A CD22–Shp1 phosphatase axis controls integrin β7 display and B cell function in mucosal immunity

Nature Immunology(2021)10.1038/s41590-021-00862-z

N/A

0DataRank · unranked

31 citations

Martin Brennan, Carolin Brandl, Ningguo Feng, Jeremy Berri, Julian Cheng +13 more

Endothelial Heparan Sulfate Mediates Hepatic Neutrophil Trafficking and Injury during Staphylococcus aureus Sepsis

mBio(2021)10.1128/mbio.01181-21

N/A

0DataRank · unranked

26 citations

Alejandro Gómez Toledo, Alex Márki, James T. Sorrentino, Claire Morris, Raquel Jewel Riley +12 more

Thymus-Derived CD4+CD8+ Cells Reside in Mediastinal Adipose Tissue and the Aortic Arch

The Journal of Immunology(2021)10.4049/jimmunol.2100208

N/A

0DataRank · unranked

5 citations

Yanal Ghosheh, Kouji Kobiyama, William B. Kiosses, Marco Orecchioni, Erik Ehinger +11 more

A CD22‐Shp1 phosphatase axis controls integrin β 7 display and B cell function in mucosal immunity

The FASEB Journal(2021)10.1096/fasebj.2021.35.s1.02188

N/A

0DataRank · unranked

0 citations

Martin Brennan, Carolin Brandl, Ningguo Feng, Jeremy Berri, Julian Cheng +13 more

Olfactory receptor 2 in vascular macrophages drives atherosclerosis by NLRP3-dependent IL-1 production

Science(2022)10.1126/science.abg3067

N/A

0DataRank · unranked

229 citations

Kouji Kobiyama, Holger Winkels, Yanal Ghosheh, Sara McArdle, Zbigniew Mikulski +24 more

Integrated single-cell analysis-based classification of vascular mononuclear phagocytes in mouse and human atherosclerosis

Cardiovascular Research(2022)10.1093/cvr/cvac161

N/A

0DataRank · unranked

175 citations

Florian Erhard, Tobias Weinberger, Christian Schulz, Klaus Ley, Antoine‐Emmanuel Saliba +2 more

Molecular mechanisms of leukocyte β2 integrin activation

Blood(2022)10.1182/blood.2021013500

N/A

0DataRank · unranked

65 citations

Markus Moser, Klaus Ley, Lai Wen

Olfactory receptors in macrophages and inflammation

Frontiers in Immunology(2022)10.3389/fimmu.2022.1029244

N/A

0DataRank · unranked

58 citations

Hiroaki Matsunami, Klaus Ley, Marco Orecchioni

Neuroinflammation Plays a Critical Role in Cerebral Cavernous Malformation Disease

Circulation Research(2022)10.1161/circresaha.122.321129

N/A

0DataRank · unranked

55 citations

Bliss Nelsen, Eduardo Frías-Anaya, Helios Gallego-Gutiérrez, Marco Orecchioni, Victoria Herrera +7 more

Single cell transcriptomics and TCR reconstruction reveal CD4 T cell response to MHC-II-restricted APOB epitope in human cardiovascular disease

Nature Cardiovascular Research(2022)10.1038/s44161-022-00063-3

N/A

0DataRank · unranked

48 citations

Payel Roy, Antoine Freuchet, Rishab Gulati, Yanal Ghosheh, Sujit Silas Armstrong Suthahar +20 more

The expanding family of neutrophil‐derived extracellular vesicles

Immunological Reviews(2022)10.1111/imr.13103

N/A

0DataRank · unranked

43 citations

Klaus Ley, Alex Márki

Titration of 124 antibodies using CITE-Seq on human PBMCs

Scientific Reports(2022)10.1038/s41598-022-24371-7

N/A

0DataRank · unranked

28 citations

Sujit Silas Armstrong Suthahar, Christopher P. Durant, Rafael Blanco-Domínguez, Payel Roy, Marco Orecchioni +3 more

Sex Differences in Coronary Artery Disease and Diabetes Revealed by scRNA-Seq and CITE-Seq of Human CD4+ T Cells

International Journal of Molecular Sciences(2022)10.3390/ijms23179875

N/A

0DataRank · unranked

25 citations

Jenifer Vallejo, Rishab Gulati, Sujit Silas Armstrong Suthahar, Vasantika Suryawanshi, Ahmad Alimadadi +15 more

A humanized β2 integrin knockin mouse reveals localized intra- and extravascular neutrophil integrin activation in vivo

Cell Reports(2022)10.1016/j.celrep.2022.110876

N/A

0DataRank · unranked

16 citations

Alex Márki, Zhihao Wang, Marco Orecchioni, Jeffrey Makings, Monica Billitti +7 more

Deleting interleukin-10 from myeloid cells exacerbates atherosclerosis in Apoe−/− mice

Cellular and Molecular Life Sciences(2022)10.1007/s00018-022-04649-9

N/A

0DataRank · unranked

16 citations

Dennis Wolf, Vasantika Suryawanshi, Holger Winkels, Kouji Kobiyama, Jeffrey Makings +3 more

Chemokine Receptor Activation Enhances Memory B Cell Class Switching Linked to IgE Sensitization to Alpha Gal and Cardiovascular Disease

Frontiers in Cardiovascular Medicine(2022)10.3389/fcvm.2021.791028

N/A

0DataRank · unranked

13 citations

Jeffrey M. Wilson, Loren D. Erickson, Lisa J. Workman, Hui Qiao, Yanal Ghosheh +9 more

Structural Basis of β2 Integrin Inside—Out Activation

Cells(2022)10.3390/cells11193039

N/A

0DataRank · unranked

13 citations

Qingkang Lyu, Klaus Ley, Benjamin T. Goult, Lai Wen

De-stressing plaques attenuates atherosclerosis progression

Trends in Immunology(2022)10.1016/j.it.2022.06.008

N/A

0DataRank · unranked

5 citations

Klaus Ley, Felix Sebastian Nettersheim

Single-Cell Antibody Sequencing in Atherosclerosis Research

Methods in molecular biology(2022)10.1007/978-1-0716-1924-7_46

N/A

0DataRank · unranked

7 citations

Christopher P. Durant, Vasantika Suryawanshi, Klaus Ley, Ryosuke Saigusa

Kindlin2 enables EphB/ephrinB bi-directional signaling to support vascular development

Life Science Alliance(2022)10.26508/lsa.202201800

N/A

0DataRank · unranked

4 citations

Lai Wen, Bhavisha Rathod, Anne‐Claude Gingras, Klaus Ley, Ho-Sup Lee +1 more

Flow Cytometry and Mass Cytometry for Measuring the Immune Cell Infiltrate in Atherosclerotic Arteries

Methods in molecular biology(2022)10.1007/978-1-0716-1924-7_47

N/A

0DataRank · unranked

3 citations

Melissa A. Meyer, Catherine C. Hedrick, Klaus Ley, Marco Orecchioni

A new β 2 integrin activation reporter mouse reveals localized intra‐ and extra‐vascular neutrophil integrin activation in vivo

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r3031

N/A

0DataRank · unranked

0 citations

Alex Márki, Zhihao Wang, Marco Orecchioni, Jeffrey Makings, Kenneth Kim +4 more

Pairing of single-cell RNA analysis and T cell antigen receptor profiling indicates breakdown of T cell tolerance checkpoints in atherosclerosis

Nature Cardiovascular Research(2023)10.1038/s44161-023-00218-w

N/A

0DataRank · unranked

76 citations

Xi Zhang, Shu Lu, Chuankai Zhang, Zhe Ma, Rui Su +16 more

Cell-autonomous regulation of complement C3 by factor H limits macrophage efferocytosis and exacerbates atherosclerosis

Immunity(2023)10.1016/j.immuni.2023.06.026

N/A

0DataRank · unranked

74 citations

Nikolina Papac-Miličević, Florentina Porsch, Dimitrios Tsiantoulas, Tim Hendrikx, Minoru Takaoka +19 more

Identification of human exTreg cells as CD16+CD56+ cytotoxic CD4+ T cells

Nature Immunology(2023)10.1038/s41590-023-01589-9

N/A

0DataRank · unranked

60 citations

Payel Roy, Sujit Silas Armstrong Suthahar, Mohammad Oliaeimotlagh, Sunil Kumar, Marco Orecchioni +12 more

Single-cell profiling reveals inflammatory polarization of human carotid versus femoral plaque leukocytes

JCI Insight(2023)10.1172/jci.insight.171359

N/A

0DataRank · unranked

40 citations

Arjun Sinha, Matthew DeBerge, Shalini Singh, Harris Avgousti, I R Lee +23 more

Single cell transcriptomics reveals recent CD8T cell receptor signaling in patients with coronary artery disease

Frontiers in Immunology(2023)10.3389/fimmu.2023.1239148

N/A

0DataRank · unranked

16 citations

Ryosuke Saigusa, Amir Khan, Mohammad Oliaeimotlagh, Sujit Silas Armstrong Suthahar, Sunil Kumar +7 more

Single-cell transcriptomes and T cell receptors of vaccine-expanded apolipoprotein B-specific T cells

Frontiers in Cardiovascular Medicine(2023)10.3389/fcvm.2022.1076808

N/A

0DataRank · unranked

6 citations

Yanal Ghosheh, Holger Winkels, Kouji Kobiyama, Christopher P. Durant, Sujit Silas Armstrong Suthahar +7 more

Dysregulated cellular metabolism in atherosclerosis: mediators and therapeutic opportunities

Nature Metabolism(2024)10.1038/s42255-024-01015-w

N/A

0DataRank · unranked

62 citations

Felix Sebastian Nettersheim, Brian G. Coon, Alexandra C Finney, Martin A. Schwartz, Klaus Ley +3 more

Mild Hypoxia Accelerates Cerebral Cavernous Malformation Disease Through CX3CR1-CX3CL1 Signaling

Arteriosclerosis Thrombosis and Vascular Biology(2024)10.1161/atvbaha.123.320367

N/A

0DataRank · unranked

20 citations

Helios Gallego-Gutiérrez, Brendan Gongol, Shantel Weinsheimer, Catherine Chinhchu Lai, Marco Orecchioni +23 more

Olfr2-positive macrophages originate from monocytes proliferate in situ and present a pro-inflammatory foamy-like phenotype

Cardiovascular Research(2024)10.1093/cvr/cvae153

N/A

0DataRank · unranked

17 citations

Felix Sebastian Nettersheim, Ahmad Alimadadi, Erpei Wang, Monica Billitti, Natalya Resto-Trujillo +5 more

Single Cell High Dimensional Analysis of Human Peripheral Blood Mononuclear Cells Reveals Unique Intermediate Monocyte Subsets Associated with Sex Differences in Coronary Artery Disease

International Journal of Molecular Sciences(2024)10.3390/ijms25052894

N/A

0DataRank · unranked

15 citations

Ravi K. Komaravolu, Christopher P. Durant, Runpei Wu, Chantel McSkimming, Fabrizio Drago +9 more

PD-1 and CD73 on naive CD4+ T cells synergistically limit responses to self

Nature Immunology(2024)10.1038/s41590-024-02021-6

N/A

0DataRank · unranked

9 citations

Simon Brunel, Robert S. Sinkovits, Sujit Silas Armstrong Suthahar, Payel Roy, Monica Billitti +10 more

Identification of apolipoprotein B–reactive CDR3 motifs allows tracking of atherosclerosis-related memory CD4+T cells in multiple donors

Frontiers in Immunology(2024)10.3389/fimmu.2024.1302031

N/A

0DataRank · unranked

6 citations

Sujit Silas Armstrong Suthahar, Jeffrey Makings, Klaus Ley, Payel Roy

CITE-seq analysis reveals human cytomegalovirus and diabetes-associated adaptive NK cell alterations in cardiovascular disease

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.22.581997

N/A

0DataRank · unranked

1 citations

Daniel Chen, Sunil Kumar, James R. Heath, Matthew J. Feinstein, John R. Greenland +5 more

ThresholdR: An Automated Method for Thresholding CITE-seq-based Antibody Expression Data for Immune Cells

The Journal of Immunology(2024)10.4049/jimmunol.212.supp.0261.5438

N/A

0DataRank · unranked

0 citations

Sunil Kumar, Amir Khan, Sujit Silas Armstrong Suthahar, Vasantika Suryawanshi, Jeffrey Makings +8 more

Loss of effector Treg signature in APOB-reactive CD4+ T cells in patients with coronary artery disease

Nature Cardiovascular Research(2025)10.1038/s44161-025-00671-9

N/A

0DataRank · unranked

5 citations

A. Bellapu, Sujit Silas Armstrong Suthahar, Mohammad Oliaeimotlagh, Qingkang Lyu, Smriti Parashar +9 more

ER stress induced mitochondrial dysfunction drives Treg instability in coronary artery disease

EMBO Molecular Medicine(2025)10.1038/s44321-025-00322-3

N/A

0DataRank · unranked

5 citations

Mohammad Oliaeimotlagh, Payel Roy, Qingkang Lyu, A. Bellapu, M. V. Fomin +6 more

Functional unfolding of the integrin αX transmembrane helix

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2507966122

N/A

0DataRank · unranked

3 citations

Minhyeong Lee, Alan J. Situ, Woojin An, Klaus Ley, Chungho Kim +2 more

Automated denoising of CITE-seq data with ThresholdR

Cell Reports Methods(2025)10.1016/j.crmeth.2025.101088

N/A

0DataRank · unranked

1 citations

Sunil Kumar, Aleksandr Taraskin, Sujit Silas Armstrong Suthahar, Vasantika Suryawanshi, Austin W.T. Chiang +2 more

Nanoscopy reveals integrin clustering reliant on kindlin-3 but not talin-1

Cell Communication and Signaling(2025)10.1186/s12964-024-02024-8

N/A

0DataRank · unranked

3 citations

Ziming Cao, Wei Liu, Jason G. Cahoon, Kepeng Wang, Penghua Wang +8 more

Functional Role of Single-Nucleotide Polymorphisms on IFNG and IFNGR1 in Humans with Cardiovascular Disease

International Journal of Molecular Sciences(2025)10.3390/ijms26188806

N/A

0DataRank · unranked

0 citations

Yang Li, Smriti Parashar, Catalina Ramirez, Heather McKay, Alan Landay +10 more

Proinflammatory and cytotoxic CD38+HLA-DR+ effector memory CD8+ T cells are peripherally expanded in human cardiac allograft vasculopathy

American Journal of Transplantation(2025)10.1016/j.ajt.2025.10.015

N/A

0DataRank · unranked

0 citations

Sujit Silas Armstrong Suthahar, Payel Roy, Vasantika Suryawanshi, Runpei Wu, Erpei Wang +9 more

Hyperinsulinemia promotes atherosclerosis by inducing metabolic reprogramming of autoreactive CD4+ T cells 2359

The Journal of Immunology(2025)10.1093/jimmun/vkaf283.285

N/A

0DataRank · unranked

0 citations

Marco Orecchioni, Payel Roy, Monica Billitti, Thomas Riffelmacher, Mohammad Oliaeimotlagh +9 more

Single-cell eQTL mapping in PBMCs reveals genes that modulate the immune response in atherosclerosis 3202

The Journal of Immunology(2025)10.1093/jimmun/vkaf283.1028

N/A

0DataRank · unranked

0 citations

Smriti Parashar, Klaus Ley, Megh Mehta

Defective autophagy drives the transition from regulatory Tregs to cytotoxic exTreg CD4+ T cells 3167

The Journal of Immunology(2025)10.1093/jimmun/vkaf283.998

N/A

0DataRank · unranked

0 citations

Mohammad Oliaeimotlagh, Payel Roy, Qingkang Lyu, M. V. Fomin, Klaus Ley +1 more

Elongated neutrophil-derived structures are blood-borne microparticles formed by rolling neutrophils during sepsis

The Journal of Experimental Medicine(2020)10.1084/jem.20200551

N/A

0DataRank · unranked

57 citations

Konrad Buscher, Cristina B. Lorenzini, Matthew Meyer, Ryosuke Saigusa, Zhichao Fan +20 more

A CD25–chemokine receptor complex initiates noncanonical IL-2 signaling

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110981

N/A

0DataRank · unranked

0 citations

Sarah Hyun Ji Kim, Javid Aceil, Amelia Meecham, Alexandre R. Gingras, Klaus Ley +3 more

Imaging of the immune system – towards a subcellular and molecular understanding

Journal of Cell Science(2020)10.1242/jcs.234922

N/A

0DataRank · unranked

16 citations

Zhichao Fan, Zbigniew Mikulski, Klaus Ley, Lai Wen

Klaus Ley

Indexed papers

Top data-sharing exemplar

Papers