Kun Leng

Also affiliated with Institute for Neurodegenerative Disorders

NeuroscienceMedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 24 papers. Top paper: “A CRISPRi/a platform in human iPSC-derived microglia uncovers regulators of disease states”.

A CRISPRi/a platform in human iPSC-derived microglia uncovers regulators of disease states

Nature Neuroscience(2022)10.1038/s41593-022-01131-4

N/A

4.1DataRank · unranked

252 citations

Sydney M. Sattler, Cindy Huang, Olivia M. Teter, Kun Leng, Sayed Hadi Hashemi +14 more

Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors

eLife(2022)10.7554/elife.81856

N/A

2.4DataRank · unranked

159 citations

Jessica L. Bonnar, Angela N. Pogson, Christina R. Liem, Nolan K Maier, Yufang Ding +13 more

Molecular characterization of selectively vulnerable neurons in Alzheimer’s disease

Nature Neuroscience(2021)10.1038/s41593-020-00764-7

N/A

0.929DataRank · unranked

488 citations

Emmy Li, Rana Eser, Antonia M. H. Piergies, Rene Sit, Michelle Tan +13 more

Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis

Nature Neuroscience(2021)10.1038/s41593-021-00862-0

N/A

0.906DataRank · unranked

420 citations

Anthony Abarientos, Jason Hong, Sayed Hadi Hashemi, Rui Yan, Nina M. Dräger +7 more

Granulin loss of function in human mature brain organoids implicates astrocytes in TDP-43 pathology

Stem Cell Reports(2023)10.1016/j.stemcr.2023.01.012

N/A

0.571DataRank · unranked

44 citations

Mark Koontz, Elise Marsan, Nir Salinas, Marina Ramsey, Yien–Ming Kuo +13 more

CRISPRi screens in human astrocytes elucidate regulators of distinct inflammatory reactive states

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.23.457400

N/A

0.449DataRank · unranked

19 citations

Indigo V.L. Rose, Hyosung Kim, Wenlong Xia, Wilber Romero‐Fernandez, Brenda L. Rooney +15 more

Patterns of neuronal Rhes as a novel hallmark of tauopathies

Acta Neuropathologica(2021)10.1007/s00401-021-02279-2

N/A

0.373DataRank · unranked

11 citations

Kun Leng, Kaitlyn N. Letourneau, Israel Hernández, Caroline Lew, William W. Seeley +7 more

Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.13.499814

N/A

0.345DataRank · unranked

9 citations

Jessica L. Bonnar, Angela N. Pogson, Christina R. Liem, Nolan K Maier, Yufang Ding +13 more

Towards elucidating disease-relevant states of neurons and glia by CRISPR-based functional genomics

Genome Medicine(2022)10.1186/s13073-022-01134-7

N/A

0.330DataRank · unranked

8 citations

Martin Kampmann, Kun Leng

CRISPRi-based screen of Autism Spectrum Disorder risk genes in microglia uncovers roles of ADNP in microglia endocytosis and synaptic pruning

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.06.01.596962

N/A

0.208DataRank · unranked

3 citations

Amanda McQuade, Venus Hagan, Weiwei Liang, Nina M. Dräger, Sydney M. Sattler +9 more

Realtime observation of ATP-driven single B 12 molecule translocation through BtuCD-F

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.12.02.518935

N/A

0.208DataRank · unranked

3 citations

Jinrang Kim, Kun Leng, John E. Ramos, Colin D. Kinz-Thompson, Nathan K. Karpowich +3 more

Cell-Type Specificity of Mosaic Chromosome 1q Gain Resolved by snRNA-seq in a Case of Epilepsy With Hyaline Protoplasmic Astrocytopathy

Neurology Genetics(2024)10.1212/nxg.0000000000200142

N/A

0.178DataRank · unranked

2 citations

Cathryn R. Cadwell, W. Patrick Devine, Tarık Tihan, Zhongxia Qi, Nilika S. Singhal +9 more

Mechanistic implications of the interaction of the soluble substrate-binding protein with a type II ABC importer

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.12.02.518933

N/A

0.165DataRank · unranked

2 citations

Jinrang Kim, Kun Leng, John E. Ramos, Colin D. Kinz-Thompson, Nathan K. Karpowich +3 more

Granulin Loss of Function in Human Mature Brain Organoids Implicates Astrocytes in TDP-43 Pathology

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.24.513566

N/A

0.104DataRank · unranked

1 citations

Mark Koontz, Elise Marsan, Nir Salinas, Marina Ramsey, Yien–Ming Kuo +13 more

Increased Synapse Elimination by Inflammatory Cells Contributes to Long-lasting Post-Stroke Memory Dysfunction in Old Mice

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.13.659591

N/A

0DataRank · unranked

2 citations

Peipei Pan, Qifeng Li, Zhanqiang Wang, Kun Leng, Shalika Sangras +10 more

Mislocalization and clearance of neuronal Rhes as a novel hallmark of tauopathies

medRxiv(2020)10.1101/2020.10.27.20220954

N/A

0DataRank · unranked

2 citations

Kun Leng, Israel Hernández, Caroline Lew, William W. Seeley, Salvatore Spina +6 more

mTOR activation induces endolysosomal remodeling and nonclassical secretion of IL-32 via exosomes in inflammatory reactive astrocytes

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.11.459904

N/A

0DataRank · unranked

11 citations

Brenda L. Rooney, Frank McCarthy, Wenlong Xia, Indigo V.L. Rose, Sophie Bax +9 more

Reactive astrocytes transduce inflammation in a blood-brain barrier model through a TNF-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin

Nature Communications(2022)10.1038/s41467-022-34412-4

N/A

0DataRank · unranked

188 citations

Kun Leng, Jinhee Park, Alexander G. Sorets, Suil Kim, Alena Shostak +15 more

Phenotypic Screening Using High-Content Imaging to Identify Lysosomal pH Modulators in a Neuronal Cell Model

ACS Chemical Neuroscience(2022)10.1021/acschemneuro.1c00804

N/A

0DataRank · unranked

16 citations

Kean-Hooi Ang, Julia L. Davies, Carolina Alquézar, Virginia Garda, Brenda L. Rooney +5 more

Reactive astrocytes transduce blood-brain barrier dysfunction through a TNFα-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.21.481336

N/A

0DataRank · unranked

5 citations

Kun Leng, Jinhee Park, Alexander G. Sorets, Suil Kim, Alena Shostak +7 more

mTOR activation induces endolysosomal remodeling and nonclassical secretion of IL-32 via exosomes in inflammatory reactive astrocytes

Journal of Neuroinflammation(2024)10.1186/s12974-024-03165-w

N/A

0DataRank · unranked

17 citations

Brenda L. Rooney, Frank McCarthy, Wenlong Xia, Indigo V.L. Rose, Sophie Bax +9 more

Evaluation of AAV Capsids and Delivery Approaches for Hereditary Hemorrhagic Telangiectasia Gene Therapy

Translational Stroke Research(2024)10.1007/s12975-024-01275-4

N/A

0DataRank · unranked

5 citations

Rich Liang, Kelly Press, Annika Schmidt, Zahra Shabani, Kun Leng +8 more

Evaluation of Aav Capsids and Delivery Approaches for Hereditary Hemorrhagic Telangiectasia Gene Therapy

Research Square(2024)10.21203/rs.3.rs-4469011/v1

N/A

0DataRank · unranked

0 citations

Rich Liang, Kelly Press, Annika Schmidt, Zahra Shabani, Kun Leng +8 more

Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.27.175679

N/A

0DataRank · unranked

40 citations

Anthony Abarientos, Jason Hong, Sayed Hadi Hashemi, Rui Yan, Nina M. Dräger +7 more