Jóhann E. Guðjónsson

Immunology and MicrobiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 3%percentile

1.1Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

A Roadmap for a Consensus Human Skin Cell Atlas and Single-Cell Data Standardization

Journal of Investigative Dermatology(2023)10.1016/j.jid.2023.03.1679

Top 19%

1.1DataRank

Top 19%30 citations

Hao Yuan, Karl Annusver, Raúl Ramos, Yingzi Liu, Julie Wiedemann +14 more

Papers

Driven by 135 papers — median percentile 81. Top paper: “Tofacitinib blocks IFN-regulated biomarker genes in skin fibroblasts and keratinocytes in a systemic sclerosis trial”.

Tofacitinib blocks IFN-regulated biomarker genes in skin fibroblasts and keratinocytes in a systemic sclerosis trial

JCI Insight(2022)10.1172/jci.insight.159566

N/A

1.8DataRank · unranked

74 citations

Cristina M. Padilla, Lam C. Tsoi, Vivek Nagaraja, Puja Khanna, Tracy Tabib +7 more

Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target

Nature Genetics(2023)10.1038/s41588-023-01510-y

N/A

1.6DataRank · unranked

100 citations

Derek Klarin, Michael G. Levin, Joshua M. Spin, Yae Hyun Rhee, Alicia Deng +92 more

A Roadmap for a Consensus Human Skin Cell Atlas and Single-Cell Data Standardization

Journal of Investigative Dermatology(2023)10.1016/j.jid.2023.03.1679

Top 19%

1.1DataRank

Top 19%30 citations

Hao Yuan, Karl Annusver, Raúl Ramos, Yingzi Liu, Julie Wiedemann +14 more

Vitamin D3 and deconvoluting a rash

JCI Insight(2023)10.1172/jci.insight.163789

N/A

0.892DataRank · unranked

30 citations

S. Evans, José‐Marc Techner, Robert M. Rothbaum, Luisa Christensen, Venus Onay +10 more

KLK6 expression in skin induces PAR1-mediated psoriasiform dermatitis and inflammatory joint disease

Journal of Clinical Investigation(2020)10.1172/jci133159

N/A

0.624DataRank · unranked

63 citations

J. Ludwig, Yi Fritz, Richard Rozic, William R. Swindell, Lam C. Tsoi +16 more

Biogeographic and disease-specific alterations in epidermal lipid composition and single-cell analysis of acral keratinocytes

JCI Insight(2022)10.1172/jci.insight.159762

N/A

0.524DataRank · unranked

32 citations

Stephanie T. Le, Claire Alexanian, Atrin Toussi, Yixuan Xie, Alina I. Marusina +22 more

Machine-learning classification identifies patients with early systemic sclerosis as abatacept responders via CD28 pathway modulation

JCI Insight(2022)10.1172/jci.insight.155282

N/A

0.419DataRank · unranked

10 citations

Monica E. Espinoza, Jennifer M. Franks, Yiwei Yuan, Yue Wang, Tammara Wood +6 more

Th17-skewed inflammation due to genetic deficiency of a cadherin stress sensor

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.01.406587

N/A

0.297DataRank · unranked

5 citations

Quinn R. Roth‐Carter, Jennifer L. Koetsier, Lam C. Tsoi, Joshua A. Broussard, Gillian N. Fitz +19 more

Systemic sclerosis: pathogenic mechanisms and their implications for treatment

Seminars in Immunopathology(2025)10.1007/s00281-025-01065-6

N/A

0.241DataRank · unranked

4 citations

Valérie Lecureur, Jóhann E. Guðjónsson, Dinesh Khanna, Alain Lescoat

TNF-α regulates diabetic macrophage function through the histone acetyltransferase MOF

JCI Insight(2020)10.1172/jci.insight.132306

N/A

0DataRank · unranked

53 citations

Frank M. Davis, Amrita Joshi, Sonya Wolf, Ronald M. Allen, Jay H. Lipinski +9 more

Causal Relationship and Shared Genetic Loci between Psoriasis and Type 2 Diabetes through Trans-Disease Meta-Analysis

Journal of Investigative Dermatology(2020)10.1016/j.jid.2020.11.025

N/A

0DataRank · unranked

53 citations

Philip E. Stuart, Haihan Zhang, Qingyuan Zhao, Xianyong Yin, Kevin He +11 more

IL18-containing 5-gene signature distinguishes histologically identical dermatomyositis and lupus erythematosus skin lesions

JCI Insight(2020)10.1172/jci.insight.139558

N/A

0DataRank · unranked

50 citations

Mehrnaz Gharaee‐Kermani, Céline C. Berthier, Tori Nault, Grace A. Hile, Shannon N. Estadt +8 more

Comparison of Lesional Juvenile Myositis and Lupus Skin Reveals Overlapping Yet Unique Disease Pathophysiology

Arthritis & Rheumatology(2020)10.1002/art.41615

N/A

0DataRank · unranked

34 citations

Lauren M. Pachman, Lori Lowe, Lam C. Tsoi, Sultan Elhaj, Rajasree Menon +6 more

Hyperlipidaemia and IFNgamma/TNFalpha Synergism are associated with cholesterol crystal formation in Endothelial cells partly through modulation of Lysosomal pH and Cholesterol homeostasis

EBioMedicine(2020)10.1016/j.ebiom.2020.102876

N/A

0DataRank · unranked

24 citations

Amit K. Dey, Cristhian A. Gutierrez‐Huerta, Noor Khalil, Yusuke Sekine, Gregory E. Sanda +22 more

When bugs and drugs conspire: driving acneiform skin toxicity

Journal of Clinical Investigation(2020)10.1172/jci133787

N/A

0DataRank · unranked

3 citations

Mrinal K. Sarkar, Jóhann E. Guðjónsson, Allison C. Billi

Single Cell and Spatial Transcriptomics Defines the Cellular Architecture of the Antimicrobial Response Network in Human Leprosy Granulomas

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.01.406819

N/A

0DataRank · unranked

8 citations

Travis K. Hughes, Rosane M. B. Teles, Priscila R. Andrade, Bruno Jorge de Andrade Silva, Olesya Plazyo +14 more

Inhibition of macrophage histone demethylase JMJD3 protects against abdominal aortic aneurysms

The Journal of Experimental Medicine(2021)10.1084/jem.20201839

N/A

0DataRank · unranked

151 citations

Lam C. Tsoi, William J. Melvin, Aaron D. denDekker, Rachael Wasikowski, Amrita Joshi +12 more

Transcriptomic characterization of prurigo nodularis and the therapeutic response to nemolizumab

Journal of Allergy and Clinical Immunology(2021)10.1016/j.jaci.2021.10.004

N/A

0DataRank · unranked

94 citations

Fériel Hacini‐Rachinel, Paul Fogel, François Rousseau, Xianying Xing, Matthew T. Patrick +11 more

Associations between COVID-19 and skin conditions identified through epidemiology and genomic studies

Journal of Allergy and Clinical Immunology(2021)10.1016/j.jaci.2021.01.006

N/A

0DataRank · unranked

73 citations

Haihan Zhang, Rachael Wasikowski, Errol P. Prens, Stephan Weidinger, Jóhann E. Guðjónsson +4 more

NIX initiates mitochondrial fragmentation via DRP1 to drive epidermal differentiation

Cell Reports(2021)10.1016/j.celrep.2021.108689

N/A

0DataRank · unranked

72 citations

Mariko Tokito, Ranjitha Uppala, Mrinal K. Sarkar, Jóhann E. Guðjónsson, Erika L.F. Holzbaur +1 more

Netherton syndrome subtypes share IL-17/IL-36 signature with distinct IFN-α and allergic responses

Journal of Allergy and Clinical Immunology(2021)10.1016/j.jaci.2021.08.024

N/A

0DataRank · unranked

61 citations

Mathilde Bonnet des Claustres, Matthias Fahrner, Evgeniya Petrova, Lam C. Tsoi, Olivier Gouin +9 more

Sex Bias and Autoimmune Diseases

Journal of Investigative Dermatology(2021)10.1016/j.jid.2021.06.008

N/A

0DataRank · unranked

59 citations

Allison C. Billi, Jóhann E. Guðjónsson, Enze Xing

Translational implications of Th17-skewed inflammation due to genetic deficiency of a cadherin stress sensor

Journal of Clinical Investigation(2021)10.1172/jci144363

N/A

0DataRank · unranked

59 citations

Quinn R. Roth‐Carter, Jennifer L. Koetsier, Lam C. Tsoi, Amber L. Huffine, Joshua A. Broussard +21 more

Endoplasmic reticulum stress sensor IRE1α propels neutrophil hyperactivity in lupus

Journal of Clinical Investigation(2021)10.1172/jci137866

N/A

0DataRank · unranked

58 citations

Basel H. Abuaita, Paul A. Steffes, Andrew T. Fernandes, Shanea K. Estes, Craig J. Dobry +6 more

B Cell Signatures Distinguish Cutaneous Lupus Erythematosus Subtypes and the Presence of Systemic Disease Activity

Frontiers in Immunology(2021)10.3389/fimmu.2021.775353

N/A

0DataRank · unranked

51 citations

Stephanie Lazar, Jasmine Stannard, Lam C. Tsoi, Sean Eddy, Syed Rizvi +10 more

New Frontiers in Psoriatic Disease Research, Part I: Genetics, Environmental Triggers, Immunology, Pathophysiology, and Precision Medicine

Journal of Investigative Dermatology(2021)10.1016/j.jid.2021.02.764

N/A

0DataRank · unranked

47 citations

Jóhann E. Guðjónsson, Stephanie T. Le, Emanual Maverakis, Olesya Plazyo, Christopher T. Ritchlin +6 more

IFN-κ Is a Rheostat for Development of Psoriasiform Inflammation

Journal of Investigative Dermatology(2021)10.1016/j.jid.2021.05.029

N/A

0DataRank · unranked

19 citations

Shannon N. Estadt, Lam C. Tsoi, Sonya Wolf, Jianhua Liu, Xianying Xing +8 more

IRAK2 Has a Critical Role in Promoting Feed-Forward Amplification of Epidermal Inflammatory Responses

Journal of Investigative Dermatology(2021)10.1016/j.jid.2021.03.019

N/A

0DataRank · unranked

17 citations

Lam C. Tsoi, William R. Swindell, Jiaoling Chen, Ranjitha Uppala, Allison C. Billi +23 more

Dynamic manifestation of autoimmune diseases in skin—cytokine hubs and paradoxic reactions

Journal of Allergy and Clinical Immunology(2021)10.1016/j.jaci.2021.11.014

N/A

0DataRank · unranked

3 citations

Allison C. Billi, Jóhann E. Guðjónsson, Shuai Shao

203 Non-lesional and lesional lupus skin share inflammatory phenotypes that drive activation of CD16+ DCs

Abstracts(2021)10.1136/lupus-2021-lupus21century.7

N/A

0DataRank · unranked

0 citations

Feiyang Ma, Olesya Plazyo, Rachael Wasikowski, Mehrnaz Gharaee‐Kermani, Amy Hurst +5 more

Novel insights into atopic dermatitis

Journal of Allergy and Clinical Immunology(2022)10.1016/j.jaci.2022.10.023

N/A

0DataRank · unranked

269 citations

Allison C. Billi, Emanual Maverakis, Lam C. Tsoi, Jóhann E. Guðjónsson, Charles F. Schuler

TREM2 macrophages induced by human lipids drive inflammation in acne lesions

Science Immunology(2022)10.1126/sciimmunol.abo2787

N/A

0DataRank · unranked

154 citations

Feiyang Ma, Priscila R. Andrade, Rosane M. B. Teles, Bruno Jorge de Andrade Silva, Chanyue Hu +21 more

Nonlesional lupus skin contributes to inflammatory education of myeloid cells and primes for cutaneous inflammation

Science Translational Medicine(2022)10.1126/scitranslmed.abn2263

N/A

0DataRank · unranked

153 citations

Feiyang Ma, Olesya Plazyo, Mehrnaz Gharaee‐Kermani, Rachael Wasikowski, Grace A. Hile +12 more

Macrophage-specific inhibition of the histone demethylase JMJD3 decreases STING and pathologic inflammation in diabetic wound repair

Cellular and Molecular Immunology(2022)10.1038/s41423-022-00919-5

N/A

0DataRank · unranked

142 citations

William J. Melvin, Amrita Joshi, Sonya Wolf, Jadie Y. Moon, Frank M. Davis +18 more

Single-cell transcriptomics reveals distinct effector profiles of infiltrating T cells in lupus skin and kidney

JCI Insight(2022)10.1172/jci.insight.156341

N/A

0DataRank · unranked

77 citations

Allison C. Billi, Xianying Xing, Feiyang Ma, Mitra P. Maz, Lam C. Tsoi +6 more

Shared genetic risk factors and causal association between psoriasis and coronary artery disease

Nature Communications(2022)10.1038/s41467-022-34323-4

N/A

0DataRank · unranked

74 citations

Qinmengge Li, Rachael Wasikowski, Nehal N. Mehta, Jóhann E. Guðjónsson, James T. Elder +3 more

Antimicrobial production by perifollicular dermal preadipocytes is essential to the pathophysiology of acne

Science Translational Medicine(2022)10.1126/scitranslmed.abh1478

N/A

0DataRank · unranked

67 citations

Marc C. Liggins, Jason S. Seidman, Tran Do, Fengwu Li, Kellen Cavagnero +8 more

Proprotein convertase subtilisin/kexin type 9 is a psoriasis-susceptibility locus that is negatively related to IL36G

JCI Insight(2022)10.1172/jci.insight.141193

N/A

0DataRank · unranked

37 citations

Antonio Ji‐Xu, Atrin Toussi, Lam C. Tsoi, Stephanie T. Le, Guillaume Luxardi +15 more

Senescent Cells Accumulate in Systemic Sclerosis Skin

Journal of Investigative Dermatology(2022)10.1016/j.jid.2022.09.652

N/A

0DataRank · unranked

35 citations

Pei‐Suen Tsou, Feiyang Ma, Michael Mariani, Megan N. Mattichak, Nathan K. LeBrasseur +7 more

IL-17-induced dimerization of IL-17RA drives the formation of the IL-17 signalosome to potentiate signaling

Cell Reports(2022)10.1016/j.celrep.2022.111489

N/A

0DataRank · unranked

32 citations

Carmen Barske, Sylvie Lehmann, Emmanuelle Wirth, Joschka Willemsen, Jóhann E. Guðjónsson +6 more

Skin-Expressing lncRNAs in Inflammatory Responses

Frontiers in Genetics(2022)10.3389/fgene.2022.835740

N/A

0DataRank · unranked

32 citations

Matthew T. Patrick, Rachael Wasikowski, Jiahan Chen, Mrinal K. Sarkar, Jóhann E. Guðjónsson +2 more

Gut microbe-derived metabolite trimethylamine N-oxide activates PERK to drive fibrogenic mesenchymal differentiation

iScience(2022)10.1016/j.isci.2022.104669

N/A

0DataRank · unranked

31 citations

Swarna Bale, Priyanka Verma, Qianqian Wan, Feiyang Ma, Jóhann E. Guðjónsson +9 more

IFN-κ is critical for normal wound repair and is decreased in diabetic wounds

JCI Insight(2022)10.1172/jci.insight.152765

N/A

0DataRank · unranked

25 citations

Christopher O. Audu, Amrita Joshi, Aaron D. denDekker, William J. Melvin, Frank M. Davis +9 more

Enhanced rare disease mapping for phenome-wide genetic association in the UK Biobank

Genome Medicine(2022)10.1186/s13073-022-01094-y

N/A

0DataRank · unranked

15 citations

Redina Bardhi, Wei Zhou, James T. Elder, Jóhann E. Guðjónsson, Lam C. Tsoi +1 more

Roles Played by Stress-Induced Pathways in Driving Ethnic Heterogeneity for Inflammatory Skin Diseases

Frontiers in Immunology(2022)10.3389/fimmu.2022.845655

N/A

0DataRank · unranked

9 citations

Qinmengge Li, Sutharzan Sreeskandarajan, Irina Budunova, Zhi He, Jian Kang +4 more

Reduced SPAG17 Expression in Systemic Sclerosis Triggers Myofibroblast Transition and Drives Fibrosis

Journal of Investigative Dermatology(2022)10.1016/j.jid.2022.08.052

N/A

0DataRank · unranked

14 citations

Elisha Roberson, Bo Shi, Shervin Assassi, Brian Skaug, Fred Lee +18 more

IL-33 antagonism does not improve chronic atopic dermatitis: What can we learn?

Journal of Allergy and Clinical Immunology(2022)10.1016/j.jaci.2022.10.009

N/A

0DataRank · unranked

13 citations

Jóhann E. Guðjónsson, Charles F. Schuler

The Psoriasis Glycome: Differential Expression of Cholesterol Particle Glycans and IgA Glycans Linked to Disease Severity

Journal of Investigative Dermatology(2022)10.1016/j.jid.2022.03.030

N/A

0DataRank · unranked

2 citations

William Liakos, Dayoung Park, Forum Patel, Fariha Siddiqui, Muchena J. Kailemia +10 more

Spatial transcriptomics stratifies psoriatic disease severity by emergent cellular ecosystems

Science Immunology(2023)10.1126/sciimmunol.abq7991

N/A

0DataRank · unranked

104 citations

Ikjot Sidhu, Igor Dolgalev, Tinyi Chu, Aleksandr Prystupa, Ipsita Subudhi +20 more

Genetic and Immunological Pathogenesis of Atopic Dermatitis

Journal of Investigative Dermatology(2023)10.1016/j.jid.2023.10.019

N/A

0DataRank · unranked

69 citations

Lam C. Tsoi, Allison C. Billi, Paul W. Harms, Stephan Weidinger, Jóhann E. Guðjónsson +1 more

Differential cell composition and split epidermal differentiation in human palm, sole, and hip skin

Cell Reports(2023)10.1016/j.celrep.2023.111994

N/A

0DataRank · unranked

65 citations

Allison C. Billi, Federico Bocci, Ghaidaa Kashgari, Enze Xing, Lam C. Tsoi +13 more

Single-cell sequencing reveals Hippo signaling as a driver of fibrosis in hidradenitis suppurativa

Journal of Clinical Investigation(2023)10.1172/jci169225

N/A

0DataRank · unranked

57 citations

Feiyang Ma, Pei‐Suen Tsou, Olesya Plazyo, Mehrnaz Gharaee‐Kermani, Marta Calbet +25 more

Activation of the NLRP1 inflammasome in human keratinocytes by the dsDNA mimetic poly(dA:dT)

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2213777120

N/A

0DataRank · unranked

42 citations

Mrinal K. Sarkar, Ken Okamura, John E. Harris, Jóhann E. Guðjónsson, Katherine A. Fitzgerald +1 more

Targeting SERCA2 in organotypic epidermis reveals MEK inhibition as a therapeutic strategy for Darier disease

JCI Insight(2023)10.1172/jci.insight.170739

N/A

0DataRank · unranked

30 citations

Mrinal K. Sarkar, Shaun Egolf, Jonathan Zou, Afua Tiwaa, Brian C. Capell +3 more

Shared Genetic Risk Factors for Multiple Sclerosis/Psoriasis Suggest Involvement of Interleukin‐17 and Janus Kinase–Signal Transducers and Activators of Transcription Signaling

Annals of Neurology(2023)10.1002/ana.26672

N/A

0DataRank · unranked

18 citations

Rajan P. Nair, Kevin He, Philip E. Stuart, Allison C. Billi, Xiang Zhou +5 more

Gene Expression Signatures in Inflammatory and Sclerotic Morphea Skin and Sera Distinguish Morphea from Systemic Sclerosis

Journal of Investigative Dermatology(2023)10.1016/j.jid.2023.02.036

N/A

0DataRank · unranked

15 citations

Jane L. Zhu, Viktor Martyanov, Lam C. Tsoi, Michael E. Johnson, Grant Barber +13 more

Pathophysiology of generalized pustular psoriasis

Experimental Dermatology(2023)10.1111/exd.14768

N/A

0DataRank · unranked

30 citations

Mrinal K. Sarkar, Jóhann E. Guðjónsson, Kelly Z. Young

Pansclerotic morphea is characterized by IFN-γ responses priming dendritic cell fibroblast crosstalk to promote fibrosis

JCI Insight(2023)10.1172/jci.insight.171307

N/A

0DataRank · unranked

24 citations

Feiyang Ma, Rachael Wasikowski, Allison C. Billi, Mehrnaz Gharaee‐Kermani, Jennifer Fox +16 more

Regulation of Photosensitivity by the Hippo Pathway in Lupus Skin

Arthritis & Rheumatology(2023)10.1002/art.42460

N/A

0DataRank · unranked

20 citations

Patrick Coit, Bin Xu, Amanda Victory, Mehrnaz Gharaee‐Kermani, Shannon N. Estadt +12 more

Keratinocytes sense and eliminate CRISPR DNA through STING/IFN-κ activation and APOBEC3G induction

Journal of Clinical Investigation(2023)10.1172/jci159393

N/A

0DataRank · unranked

20 citations

Ranjitha Uppala, Chang Zeng, Allison C. Billi, Lam C. Tsoi, Austin Kidder +12 more

Transcriptional profiling of rare acantholytic disorders suggests common mechanisms of pathogenesis

JCI Insight(2023)10.1172/jci.insight.168955

N/A

0DataRank · unranked

20 citations

Hope E. Burks, Ziyou Ren, Jennifer L. Koetsier, Lam C. Tsoi, Paul W. Harms +8 more

The Histone Methyltransferase SETDB2 Modulates Tissue Inhibitors of Metalloproteinase–Matrix Metalloproteinase Activity During Abdominal Aortic Aneurysm Development

Annals of Surgery(2023)10.1097/sla.0000000000005963

N/A

0DataRank · unranked

19 citations

William J. Melvin, Kevin Mangum, Lam C. Tsoi, Amrita Joshi, Qing Cai +4 more

SARS-CoV-2 ORF8 Mediates Signals in Macrophages and Monocytes through MyD88 Independently of the IL-17 Receptor

The Journal of Immunology(2023)10.4049/jimmunol.2300110

N/A

0DataRank · unranked

14 citations

Karsen E. Shoger, Mst Shamima Khatun, Mrinal K. Sarkar, Ipsita Dey, Tiffany C. Taylor +7 more

Monogenic etiologies of persistent human papillomavirus infections: A comprehensive systematic review

Genetics in Medicine(2023)10.1016/j.gim.2023.101028

N/A

0DataRank · unranked

10 citations

Atefeh Sohanforooshan Moghaddam, Mohammad Amin Tabatabaiefar, Roya Sherkat, Leila Youssefian, Amir Hossein Saeidian +9 more

Placental transcriptome analysis of hypertensive pregnancies identifies distinct gene expression profiles of preeclampsia superimposed on chronic hypertension

BMC Medical Genomics(2023)10.1186/s12920-023-01522-x

N/A

0DataRank · unranked

9 citations

Elizabeth Langen, Olesya Plazyo, Jóhann E. Guðjónsson, Santhi K. Ganesh, Ashley Hesson

Large-scale functional inference for skin-expressing lncRNAs using expression and sequence information

JCI Insight(2023)10.1172/jci.insight.172956

N/A

0DataRank · unranked

8 citations

Sutharzan Sreeskandarajan, Alanna Shefler, Rachael Wasikowski, Mrinal K. Sarkar, Jiahan Chen +11 more

Loss of interleukin-1 beta is not protective in the lupus-prone NZM2328 mouse model

Frontiers in Immunology(2023)10.3389/fimmu.2023.1162799

N/A

0DataRank · unranked

9 citations

Jianhua Liu, Céline C. Berthier, Jóhann E. Guðjónsson, Mehrnaz Gharaee‐Kermani, Lam C. Tsoi +2 more

Retrospective pharmacogenetic study of psoriasis highlights the role of KLK7 in tumour necrosis factor signalling

British Journal of Dermatology(2023)10.1093/bjd/ljad332

N/A

0DataRank · unranked

8 citations

Matthew T. Patrick, Trilokraj Tejasvi, Mrinal K. Sarkar, Rachael Wasikowski, Philip E. Stuart +11 more

Phototherapy Restores Deficient Type I IFN Production and Enhances Antitumor Responses in Mycosis Fungoides

Journal of Investigative Dermatology(2023)10.1016/j.jid.2023.06.212

N/A

0DataRank · unranked

7 citations

Pablo Vieyra-Garcia, Theresa Benezeder, Jack D. Crouch, Ira R. Kim, John T. O’Malley +18 more

Key patient demographics shape innate immune topography in noncritical hypoxic COVID-19 pneumonia

JCI Insight(2023)10.1172/jci.insight.166110

N/A

0DataRank · unranked

1 citations

Rachael Wasikowski, Feiyang Ma, Srilakshmi Yalavarthi, Claire K. Hoy, Yu Zuo +16 more

GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets

medRxiv(2023)10.1101/2023.10.04.23296543

N/A

0DataRank · unranked

31 citations

Philip E. Stuart, John Bowes, David Ellinghaus, Joanne Nititham, Jake Saklatvala +81 more

GZMK+CD8+ T cells Target a Specific Acinar Cell Type in Sjögren’s Disease

Research Square(2023)10.21203/rs.3.rs-3601404/v1

N/A

0DataRank · unranked

19 citations

Thomas Pranzatelli, Paola Pérez, Anson T. Ku, Bruno Fernandes Matuck, Khoa Huynh +37 more

Metabolic coordination between skin epithelium and type 17 immunity sustains chronic skin inflammation

Immunity(2024)10.1016/j.immuni.2024.04.022

N/A

0DataRank · unranked

89 citations

Piotr Konieczny, Aleksandr Prystupa, Rochelle Castillo, Erica Sze-Tu, Yue Xing +12 more

Systems-based identification of the Hippo pathway for promoting fibrotic mesenchymal differentiation in systemic sclerosis

Nature Communications(2024)10.1038/s41467-023-44645-6

N/A

0DataRank · unranked

77 citations

Pei‐Suen Tsou, Mehrnaz Gharaee‐Kermani, Olesya Plazyo, Xianying Xing, Joseph Kirma +20 more

Significance of stress keratin expression in normal and diseased epithelia

iScience(2024)10.1016/j.isci.2024.108805

N/A

0DataRank · unranked

64 citations

Craig N. Johnson, Rachael Wasikowski, Allison C. Billi, Lam C. Tsoi, J. Michelle Kahlenberg +3 more

The STAT3/SETDB2 axis dictates NF-κB–mediated inflammation in macrophages during wound repair

JCI Insight(2024)10.1172/jci.insight.179017

N/A

0DataRank · unranked

22 citations

Aaron D. denDekker, Qinmengge Li, Lam C. Tsoi, Amrita Joshi, William J. Melvin +14 more

Large-scale epidemiological analysis of common skin diseases to identify shared and unique comorbidities and demographic factors

Frontiers in Immunology(2024)10.3389/fimmu.2023.1309549

N/A

0DataRank · unranked

21 citations

Matthew T. Patrick, Sutharzan Sreeskandarajan, Jian Kang, J. Michelle Kahlenberg, Jóhann E. Guðjónsson +3 more

tauFisher predicts circadian time from a single sample of bulk and single-cell pseudobulk transcriptomic data

Nature Communications(2024)10.1038/s41467-024-48041-6

N/A

0DataRank · unranked

17 citations

Michelle N. Ngo, Satya Swaroop Karri, Lam C. Tsoi, Jóhann E. Guðjónsson, Babak Shahbaba +3 more

Diabetic Wound Keratinocytes Induce Macrophage JMJD3-Mediated Nlrp3 Expression via IL-1R Signaling

Diabetes(2024)10.2337/db23-0968

N/A

0DataRank · unranked

17 citations

Christopher O. Audu, Jadie Y. Moon, Amrita Joshi, William J. Melvin, Emily Barrett +11 more

A critical role for IFN-β signaling for IFN-κ induction in keratinocytes

Frontiers in Lupus(2024)10.3389/flupu.2024.1359714

N/A

0DataRank · unranked

15 citations

Jon Musai, Yee Sun Tan, Grace A. Hile, William R. Swindell, Benjamin Klein +5 more

Disease heterogeneity and molecular classification of inflammatory palmoplantar diseases

Journal of Allergy and Clinical Immunology(2024)10.1016/j.jaci.2024.07.017

N/A

0DataRank · unranked

13 citations

Joseph Kirma, Christine M. Yee, Luke F. Bugada, Syed Rizvi, Fei Wen +13 more

Targeting CD13/Aminopeptidase N as a Novel Therapeutic Approach for Scleroderma Fibrosis

Arthritis & Rheumatology(2024)10.1002/art.42973

N/A

0DataRank · unranked

13 citations

William D. Brodie, Megan N. Mattichak, Mikel Gurrea‐Rubio, Yuzo Ikari, Caroline Foster +22 more

HERC6 regulates STING activity in a sex-biased manner through modulation of LATS2/VGLL3 Hippo signaling

iScience(2024)10.1016/j.isci.2024.108986

N/A

0DataRank · unranked

10 citations

Mrinal K. Sarkar, Kelly Z. Young, Feiyang Ma, Pritika Vemulapalli, Rachael Wasikowski +9 more

Topical Mupirocin Treatment Reduces Interferon and Myeloid Signatures in Cutaneous Lupus Erythematous Lesions Through Targeting of Staphylococcus Species

Arthritis & Rheumatology(2024)10.1002/art.43079

N/A

0DataRank · unranked

9 citations

Joseph Mears, Allison C. Billi, Sirisha Sirobhushanam, Céline C. Berthier, Annie Lu +5 more

Lupus-prone NZM2328 mice exhibit enhanced UV-induced myeloid cell recruitment and activation in a type I interferon dependent manner

Journal of Autoimmunity(2024)10.1016/j.jaut.2024.103296

N/A

0DataRank · unranked

7 citations

Alayka L. Reddy, Céline C. Berthier, Lam C. Tsoi, Deborah J. Colesa, Sonya Wolf +9 more

The histone methyltransferase Mixed-lineage-leukemia-1 drives T cell phenotype via Notch signaling in diabetic tissue repair

JCI Insight(2024)10.1172/jci.insight.179012

N/A

0DataRank · unranked

6 citations

Tyler M. Bauer, Kevin D Magnum, Christopher O. Audu, James Shadiow, Emily C. Barrett +10 more

Standardized Protocols for Clinical and Histopathological Characterization of Hidradenitis Suppurativa Tissue Specimens

Journal of Investigative Dermatology(2024)10.1016/j.jid.2024.02.041

N/A

0DataRank · unranked

3 citations

Linnea Westerkam, Franklin R. Blum, Raed Alhusayen, Falk G. Bechara, Julie Caffrey +25 more

Profiling Long Noncoding RNA in Psoriatic Skin Using Single-Cell RNA Sequencing

Journal of Investigative Dermatology(2024)10.1016/j.jid.2024.09.010

N/A

0DataRank · unranked

3 citations

Matthew T. Patrick, Sutharzan Sreeskandarajan, Mehrnaz Gharaee‐Kermani, Haihan Zhang, Qinmengge Li +9 more

Epidermal ZBP1 stabilizes mitochondrial Z-DNA to drive UV-induced IFN signaling in autoimmune photosensitivity

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.23.576771

N/A

0DataRank · unranked

6 citations

Mack B. Reynolds, Bin Xu, Mehrnaz Gharaee‐Kermani, Yiqing Gao, Céline C. Berthier +12 more

GZMK+CD8+ T cells Target A Specific Acinar Cell Type in Sjögren’s Disease

Research Square(2024)10.21203/rs.3.rs-3601404/v2

N/A

0DataRank · unranked

5 citations

Paola Pérez, Anson T. Ku, Bruno Fernandes Matuck, Khoa Huynh, Shunsuke Sakai +38 more

GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets

Nature Communications(2025)10.1038/s41467-025-56719-8

N/A

0DataRank · unranked

65 citations

Philip E. Stuart, John Bowes, David Ellinghaus, Joanne Nititham, Jake Saklatvala +89 more

Epidermal ZBP1 stabilizes mitochondrial Z-DNA to drive UV-induced IFN signaling in autoimmune photosensitivity

Science Immunology(2025)10.1126/sciimmunol.ado1710

N/A

0DataRank · unranked

40 citations

Mack B. Reynolds, Bin Xu, Mehrnaz Gharaee‐Kermani, Yiqing Gao, Céline C. Berthier +14 more

Integration of GWAS, QTLs and keratinocyte functional assays reveals molecular mechanisms of atopic dermatitis

Nature Communications(2025)10.1038/s41467-025-58310-7

N/A

0DataRank · unranked

13 citations

Mrinal K. Sarkar, Michael March, Amir Hossein Saeidian, Frank Mentch, Chen-Lin Hsieh +16 more

Techniques and analytic workflow for spatial transcriptomics and its application to allergy and inflammation

Journal of Allergy and Clinical Immunology(2025)10.1016/j.jaci.2025.01.009

N/A

0DataRank · unranked

12 citations

Matthew T. Patrick, Jingyu Zhao, Xintong Zhai, Jialin Liu, Zheng Li +7 more

GZMK+CD8+ T cells target a specific acinar cell type in Sjögren's disease

Annals of the Rheumatic Diseases(2025)10.1016/j.ard.2025.08.014

N/A

0DataRank · unranked

11 citations

Paola Pérez, Anson T. Ku, Bruno Fernandes Matuck, Khoa Huynh, Shunsuke Sakai +38 more

IgG autoantibodies in bullous pemphigoid induce a pathogenic MyD88-dependent pro-inflammatory response in keratinocytes

Nature Communications(2025)10.1038/s41467-025-62495-2

N/A

0DataRank · unranked

9 citations

Christian F. Guerrero-Juarez, Jing Li, Manuela Pigors, Shirin Emtenani, Yingzi Liu +20 more

Epigenetic alteration of smooth muscle cells regulates endothelin-dependent blood pressure and hypertensive arterial remodeling

Journal of Clinical Investigation(2025)10.1172/jci186146

N/A

0DataRank · unranked

10 citations

Qinmengge Li, Katherine Hartmann, Tyler M. Bauer, Sonya Wolf, James Shadiow +15 more

Dynamics of Th1/Th17 responses and antimicrobial pathways in leprosy skin lesions

Journal of Clinical Investigation(2025)10.1172/jci190736

N/A

0DataRank · unranked

6 citations

Feiyang Ma, Jing Lü, Jaime de Anda, Ernest Y. Lee, George W. Agak +13 more

Proteins lead the way: JAK inhibitors as a new treatment option in toxic epidermal necrolysis

Signal Transduction and Targeted Therapy(2025)10.1038/s41392-024-02122-6

N/A

0DataRank · unranked

5 citations

J. Michelle Kahlenberg, Jóhann E. Guðjónsson, Benjamin Klein

Tape strip expression profiling of juvenile dermatomyositis skin reveals mitochondrial dysfunction contributing to disease endotype

JCI Insight(2025)10.1172/jci.insight.179875

N/A

0DataRank · unranked

5 citations

Sarah Mh Vandenbergen, Madison E McClune, Christine M. Goudsmit, Sophia Matossian, Meredith Riebschleger +8 more

DOCK2 Deficiency and GATA2 Haploinsufficiency Can Underlie Critical Coronavirus Disease 2019 (COVID-19) Pneumonia

Journal of Clinical Immunology(2025)10.1007/s10875-025-01877-z

N/A

0DataRank · unranked

5 citations

Leila Youssefian, Mohammad Amin Tabatabaiefar, Amir Hossein Saeidian, Bahareh Abtahi‐Naeini, Erfan Khorram +21 more

Th17 cells with regulatory phenotype are the main IL-17F and IL-26 producers in palmoplantar pustulosis

JCI Insight(2025)10.1172/jci.insight.193038

N/A

0DataRank · unranked

5 citations

Rachael Bogle, Haihan Zhang, Xianying Xing, Mehrnaz Gharaee‐Kermani, Madalina Raducu +14 more

G-CSF Mediates Increased Renal Neutrophils and Kidney Damage in a Psoriasis Mouse Model

Hypertension(2025)10.1161/hypertensionaha.125.25111

N/A

0DataRank · unranked

4 citations

Garrett Tessmer, Bianca Nguyen, Jason M. Meyer, Mohammad Saleem, Taseer Ahmad +8 more

Reevaluating the Imiquimod Model: A Barrier to Translational Progress in Psoriasis

Journal of Investigative Dermatology(2025)10.1016/j.jid.2025.09.005

N/A

0DataRank · unranked

3 citations

Ian M. Zwerner, Jóhann E. Guðjónsson, Nicole L. Ward, Catherine C. Smith

Molecular Stratification of Antiphospholipid Syndrome Through Integrative Analysis of the Whole‐Blood RNA Transcriptome

Arthritis & Rheumatology(2025)10.1002/art.70021

N/A

0DataRank · unranked

3 citations

Feiyang Ma, Katarína Kmeťová, Sherwin Navaz, Claire K. Hoy, Cyrus Sarosh +9 more

TNF-α represses fibroblast to myofibroblast transition through the histone methyltransferase Setdb2

JCI Insight(2025)10.1172/jci.insight.190836

N/A

0DataRank · unranked

2 citations

Kevin Mangum, Samuel Buckley, James Shadiow, Amrita Joshi, Christopher O. Audu +11 more

Epidermal Interferon‐κ Drives Cutaneous Lupus‐Like Lesions, Photosensitivity, and Systemic Autoimmunity In Vivo

Arthritis & Rheumatology(2025)10.1002/art.43350

N/A

0DataRank · unranked

5 citations

Deborah J. Colesa, Yiqing Gao, Patrick A. O'Brien, Lin Zhang, Lori Lowe +10 more

Positionally distinct interferon-stimulated dermal immune-acting fibroblasts promote neutrophil recruitment in Sweet syndrome

Journal of Allergy and Clinical Immunology(2025)10.1016/j.jaci.2025.05.029

N/A

0DataRank · unranked

4 citations

Julie Albright, Fengwu Li, Edward Liu, Tatsuya Dokoshi, Rachael Bogle +13 more

IL31 identified as a key genetic risk factor for prurigo nodularis

Journal of Allergy and Clinical Immunology(2025)10.1016/j.jaci.2025.06.031

N/A

0DataRank · unranked

2 citations

Yuntian Wu, Xue Zhong, Qinmengge Li, Valérie Julia, Bingshan Li +3 more

Pemphigus Vulgaris Autoantibodies Induce an Endoplasmic Reticulum Stress Response

Journal of Investigative Dermatology(2025)10.1016/j.jid.2024.12.028

N/A

0DataRank · unranked

3 citations

Navaneetha Krishnan Bharathan, Yoshitaka SHIBATA, W. Giang, Jóhann E. Guðjónsson, John T. Seykora +5 more

Flower dependent trafficking of lamellar bodies facilitates maturation of the epidermal barrier

Nature Communications(2025)10.1038/s41467-025-62105-1

N/A

0DataRank · unranked

3 citations

Jos P.H. Smits, Patrick T Kuwong, Rachel Johnson, Louise Monga, Ivonne M.J.J. van Vlijmen‐Willems +14 more

Dichotomous STAT5 and STAT6 Activation in T Cells Reflects Cytokine Shifts Between Blood and Skin in Atopic Dermatitis

Allergy(2025)10.1111/all.16492

N/A

0DataRank · unranked

2 citations

Regina Treudler, Marie Rabe, Niklas Artz, Sabine Seiffert, Rachael Bogle +13 more

Endothelin-2 from Keratinocytes and its Association with Itch in Skin Diseases

Journal of Investigative Dermatology(2025)10.1016/j.jid.2025.07.030

N/A

0DataRank · unranked

1 citations

Mrinal K. Sarkar, Yuntian Wu, Xianying Xing, Matthew T. Patrick, Bo Duan +7 more

Inflammatory niches as spatial drivers of disease mechanisms and targets for personalized treatment

Journal of the European Academy of Dermatology and Venereology(2025)10.1111/jdv.70170

N/A

0DataRank · unranked

1 citations

Zhiqin Fang, Lam C. Tsoi, Jóhann E. Guðjónsson, Rundong Jiang

Single-cell and spatial transcriptomics implicate vascular cell orchestration of inflammatory changes after UV light exposure in skin

Journal of Investigative Dermatology(2025)10.1016/j.jid.2025.11.024

N/A

0DataRank · unranked

1 citations

Rachael Bogle, Mohammed Saeed, Lam C. Tsoi, J. Michelle Kahlenberg, Ksenia S. Anufrieva +5 more

The polygenic architecture of hidradenitis suppurativa reveals signaling mechanisms that implicate epithelial remodeling

medRxiv(2025)10.1101/2025.07.25.25332168

N/A

0DataRank · unranked

4 citations

Poppy A. Gould, Yiming Luo, Errol P. Prens, Lee Wheless, Adriana M. Hung +47 more

IL-1 signaling enrichment in inflammatory skin disease loci with higher risk allele frequencies in African ancestry

Research Square(2025)10.21203/rs.3.rs-5724270/v1

N/A

0DataRank · unranked

1 citations

Yumeng Dong, Matthew T. Patrick, Mrinal K. Sarkar, Haihan Zhang, Rachael Bogle +18 more

TWEAK Signaling Drives the Transition from Psoriasis to Atopic Dermatitis-like Inflammation in Paradoxical Skin Reactions

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.19.660481

N/A

0DataRank · unranked

0 citations

Rachael Bogle, Haihan Zhang, Jennifer Fox, Joseph Kirma, Xianying Xing +13 more

Nemolizumab Treatment Normalizes Dysregulated Microbiome in Lesional Prurigo Nodularis

Journal of Investigative Dermatology(2025)10.1016/j.jid.2025.06.1575

N/A

0DataRank · unranked

0 citations

Prasad Chaskar, Matthew T. Patrick, Kai Wang, Christophe Piketty, Valérie Julia +4 more

Loopsim: enrichment analysis of chromosome conformation capture with fast empirical distribution simulation

NAR Genomics and Bioinformatics(2025)10.1093/nargab/lqaf098

N/A

0DataRank · unranked

0 citations

Haihan Zhang, Zhaolin Zhang, Jiayu Zhou, Jóhann E. Guðjónsson, James T Elder +3 more

Cross-disease comparison of dermatomyositis and lupus skin identifies inflammatory monocytes and JAK-1 signaling as drivers of vasculopathy in dermatomyositis

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.14.664806

N/A

0DataRank · unranked

0 citations

Lin Zhang, Feiyang Ma, Mehrnaz Gharaee‐Kermani, Jessica L. Turnier, Amanda N. Victory +14 more

Targeting Plasminogen Activator Inhibitor-1 with a Novel Small Molecule Inhibitor Attenuates Lung Fibrosis

Research Square(2025)10.21203/rs.3.rs-6951289/v1

N/A

0DataRank · unranked

0 citations

S.M. Fortier, Lam C. Tsoi, Roxann Alonzo, Natalya Subbotina, Mark Warnock +8 more

Identification of disease-specific regulatory networks in prurigo nodularis versus atopic dermatitis through ATAC/RNA single-nucleus profiling

Journal of Allergy and Clinical Immunology(2025)10.1016/j.jaci.2025.08.026

N/A

0DataRank · unranked

0 citations

Rachael Bogle, Matthew T. Patrick, Gharaee-Kermani Mehrnaz, Xianying Xing, Allison C. Billi +5 more

Positionally distinct interferon-stimulated dermal immune-acting fibroblasts drive neutrophil recruitment in Sweet’s syndrome 4440

The Journal of Immunology(2025)10.1093/jimmun/vkaf283.2122

N/A

0DataRank · unranked

0 citations

Julie Albright, Lam C. Tsoi, Brian Hinds, Rachael Bogle, Tatsuya Dokoshi +13 more

A rare population of TGFB-expressing resident macrophages undergoes macrophage to myofibroblast transition during wound repair 2260

The Journal of Immunology(2025)10.1093/jimmun/vkaf283.197

N/A

0DataRank · unranked

0 citations

Lam C. Tsoi, Tyler M. Bauer, James Shadiow, Amrita Joshi, Andrea T Obi +4 more

Targeting IL-1 controls refractory Pityriasis rubra pilaris

Research Square(2023)10.21203/rs.3.rs-3433295/v1

N/A

0DataRank · unranked

0 citations

Yannik Severin, Xianying Xing, Aaron Mangold, Curdin Conrad, Pål Johannsen +21 more

RUNX1 is expressed in a subpopulation of dermal fibroblasts and is associated with disease severity of systemic sclerosis

Annals of the Rheumatic Diseases(2025)10.1016/j.ard.2025.10.033

N/A

0DataRank · unranked

0 citations

Zhiyun Gong, Helen Jarnagin, Diana M. Toledo, Tamar R. Abel, Dillon Popovich +17 more

Contribution of plasma cells and B cells to hidradenitis suppurativa pathogenesis

JCI Insight(2020)10.1172/jci.insight.139930

N/A

0DataRank · unranked

190 citations

Lam C. Tsoi, Feiyang Ma, Allison C. Billi, Kelsey R. van Straalen, Allard R.J.V. Vossen +28 more

Immunopathogenesis of hidradenitis suppurativa and response to anti–TNF-α therapy

JCI Insight(2020)10.1172/jci.insight.139932

N/A

0DataRank · unranked

151 citations

Haley B. Naik, Sean Clancy, Mariela Pauli, Kathleen M. Smith, Yingtao Bi +11 more

Cytokinocytes: the diverse contribution of keratinocytes to immune responses in skin

JCI Insight(2020)10.1172/jci.insight.142067

N/A

0DataRank · unranked

326 citations

Lam C. Tsoi, Allison C. Billi, Nicole L. Ward, Paul W. Harms, Chang Zeng +4 more

Second-Strand Synthesis-Based Massively Parallel scRNA-Seq Reveals Cellular States and Molecular Features of Human Inflammatory Skin Pathologies

Immunity(2020)10.1016/j.immuni.2020.09.015

N/A

0DataRank · unranked

279 citations

Marc H. Wadsworth, Todd M. Gierahn, Tran Do, David I. Weiss, Priscila R. Andrade +10 more

Epigenetic regulation of the PGE2 pathway modulates macrophage phenotype in normal and pathologic wound repair

JCI Insight(2020)10.1172/jci.insight.138443

N/A

0DataRank · unranked

83 citations

Lam C. Tsoi, Rachael Wasikowski, Aaron D. denDekker, Amrita Joshi, Carol A. Wilke +16 more

Targeting CD38-dependent NAD+ metabolism to mitigate multiple organ fibrosis

iScience(2020)10.1016/j.isci.2020.101902

N/A

0DataRank · unranked

64 citations

Wenxia Wang, Benjamin D. Korman, Kai Li, Qianqian Wang, Jun Wei +16 more

IL-27 signaling activates skin cells to induce innate antiviral proteins and protects against Zika virus infection

Science Advances(2020)10.1126/sciadv.aay3245

N/A

0DataRank · unranked

55 citations

Chelsea Handfield, Jutamas Suwanpradid, Peter Hoang, Michael J. McFadden, Kevin Labagnara +11 more

Characterization of circular RNA transcriptomes in psoriasis and atopic dermatitis reveals disease‐specific expression profiles

Experimental Dermatology(2020)10.1111/exd.14227

N/A

0DataRank · unranked

57 citations

Lam C. Tsoi, Ranjitha Uppala, Henrik Hager, Stephan Weidinger, Jóhann E. Guðjónsson +3 more

Jóhann E. Guðjónsson

Indexed papers

Top data-sharing exemplar

Papers