Ralph Mazitschek

Also affiliated with Harvard University, Massachusetts General Hospital, Center for Systems Biology

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 21 papers. Top paper: “UM171 glues asymmetric CRL3–HDAC1/2 assembly to degrade CoREST corepressors”.

UM171 glues asymmetric CRL3–HDAC1/2 assembly to degrade CoREST corepressors

Nature(2025)10.1038/s41586-024-08532-4

N/A

1.4DataRank · unranked

49 citations

Olivia Zhang, Xiaowen Xie, Eunju Nam, N. Connor Payne, Pallavi M. Gosavi +27 more

Rapid “mix and read” assay for scalable detection of SARS-CoV-2 antibodies in patient plasma

medRxiv(2020)10.1101/2020.09.01.20184101

N/A

0DataRank · unranked

7 citations

Radosław P. Nowak, Daan Overwijn, N. Connor Payne, Stephanie Fischinger, Caroline Atyeo +9 more

Obtusaquinone is a cysteine modifying compound that targets Keap1 for degradation

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.03.023432

N/A

0DataRank · unranked

0 citations

Cintia Carla da Hora, Aleksandar B. Kirov, Elie Tabet, Romain J. Amante, Antoinette E. Nibbs +8 more

Bright and stable luminescent probes for target engagement profiling in live cells

Nature Chemical Biology(2021)10.1038/s41589-021-00877-5

N/A

0DataRank · unranked

82 citations

Alena S. Kalyakina, Kritika Singh, Mark A. Tye, Ralph Mazitschek, N. Connor Payne

The Prolyl-tRNA Synthetase Inhibitor Halofuginone Inhibits SARS-CoV-2 Infection

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.22.436522

N/A

0DataRank · unranked

23 citations

Thomas Mandel Clausen, Chelsea Nora, Adam P. Cribbs, Andrea Denardo, Alex E. Clark +41 more

A direct high-throughput protein quantification strategy facilitates discovery and characterization of a celastrol-derived BRD4 degrader

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.08.471806

N/A

0DataRank · unranked

1 citations

Semer Maksoud, Bakhos A. Tannous, Ralph Mazitschek, N. Connor Payne

Elucidating the path to Plasmodium prolyl-tRNA synthetase inhibitors that overcome halofuginone resistance

Nature Communications(2022)10.1038/s41467-022-32630-4

N/A

0DataRank · unranked

31 citations

N. Connor Payne, C. Johansson, Kritika Singh, Sofia A. Santos, Lọla Fagbami +13 more

A direct high-throughput protein quantification strategy facilitates discovery and characterization of a celastrol-derived BRD4 degrader

Cell chemical biology(2022)10.1016/j.chembiol.2022.05.003

N/A

0DataRank · unranked

40 citations

Semer Maksoud, Bakhos A. Tannous, Ralph Mazitschek, N. Connor Payne

Collateral sensitivity as a strategy to suppress resistance emergence: the challenge of diverse evolutionary pathways

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.04.07.486819

N/A

0DataRank · unranked

0 citations

Madeline R. Luth, Mark A. Tye, Ralph Mazitschek, Sabine Ottilie, Elizabeth A. Winzeler +5 more

Oxycodone withdrawal induces HDAC1/HDAC2-dependent transcriptional maladaptations in the reward pathway in a mouse model of peripheral nerve injury

Nature Neuroscience(2023)10.1038/s41593-023-01350-3

N/A

0DataRank · unranked

21 citations

Randal A. Serafini, Aarthi Ramakrishnan, Andrew Nicolais, Ilinca M. Giosan, Claire Polizu +15 more

Prolyl-tRNA synthetase as a novel therapeutic target in multiple myeloma

Blood Cancer Journal(2023)10.1038/s41408-023-00787-w

N/A

0DataRank · unranked

17 citations

Anna James-Bott, Mark A. Tye, Leona Yamamoto, Mehmet Samur, Yu‐Tzu Tai +24 more

Diagnostic TR-FRET assays for detection of antibodies in patient samples

Cell Reports Methods(2023)10.1016/j.crmeth.2023.100421

N/A

0DataRank · unranked

6 citations

Radosław P. Nowak, Daan Overwijn, N. Connor Payne, Stephanie Fischinger, Caroline Atyeo +18 more

Diverse evolutionary pathways challenge the use of collateral sensitivity as a strategy to suppress resistance

eLife(2023)10.7554/elife.85023

N/A

0DataRank · unranked

6 citations

Madeline R. Luth, Mark A. Tye, Ralph Mazitschek, Sabine Ottilie, Elizabeth A. Winzeler +5 more

The cyclimids: Degron-inspired cereblon binders for targeted protein degradation

Cell chemical biology(2024)10.1016/j.chembiol.2024.01.003

N/A

0DataRank · unranked

42 citations

N. Connor Payne, Wenqing Xu, Chia‐Fu Chang, Nandini Vallavoju, Spencer Frome +4 more

Inhibiting the Keap1/Nrf2 Protein‐Protein Interaction with Protein‐Like Polymers

Advanced Materials(2024)10.1002/adma.202311467

N/A

0DataRank · unranked

28 citations

H. Hamilton, Madeline P. Hopps, Yang Li, Baofu Qiao, N. Connor Payne +14 more

Central inhibition of HDAC6 re-sensitizes leptin signaling during obesity to induce profound weight loss

Cell Metabolism(2024)10.1016/j.cmet.2024.02.007

N/A

0DataRank · unranked

21 citations

Yuqin Men, Alexander Bartlett, Mario Andrés Salazar Hernández, Jie Xu, Xinchi Yi +5 more

Epigenetic modulation through BET bromodomain inhibitors as a novel therapeutic strategy for progranulin-deficient frontotemporal dementia

Scientific Reports(2024)10.1038/s41598-024-59110-7

N/A

0DataRank · unranked

11 citations

Daniel M. Fass, N. Connor Payne, Angela She, Debasis Patnaik, Krista M. Hennig +13 more

Identification of a Polypeptide Inhibitor of O-GlcNAc Transferase with Picomolar Affinity

Journal of the American Chemical Society(2024)10.1021/jacs.4c08656

N/A

0DataRank · unranked

7 citations

N. Connor Payne, Victoria M. Marando, Ralph Mazitschek, Suzanne Walker, Forrest A. Hammel

Protocol for the comprehensive biochemical and cellular profiling of small-molecule degraders using CoraFluor TR-FRET technology

STAR Protocols(2024)10.1016/j.xpro.2024.103129

N/A

0DataRank · unranked

6 citations

Saki Ichikawa, Christina M. Woo, Ralph Mazitschek, N. Connor Payne

A method for the detection and enrichment of endogenous cereblon substrates

Cell chemical biology(2025)10.1016/j.chembiol.2025.07.002

N/A

0DataRank · unranked

6 citations

Yumo Li, N. Connor Payne, Zhenguang Zhao, Wenqing Xu, Alena Kroupova +12 more

Disruption of P. falciparum amino acid transporter elevates intracellular proline and induces resistance to Prolyl-tRNA synthetase inhibitors

Cell chemical biology(2025)10.1016/j.chembiol.2025.09.007

N/A

0DataRank · unranked

2 citations

Lọla Fagbami, Amy Deik, Claudia Taccheri, Akansha Pant, Madeline R. Luth +12 more