🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Andrei Thomas‐Tikhonenko

Children's Hospital of Philadelphia

ORCID: 0000-0002-2739-2206

Also affiliated with Cancer Research Center, University of Pennsylvania

MedicineBiochemistry, Genetics and Molecular BiologyImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 5%percentile
0.548Author DataRank

Indexed papers

2in pilot corpus
datarank_citation_only_1hop_v6· scope data_onlyMethodology
Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Top data-sharing exemplar

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

MAJIQlopedia: an encyclopedia of RNA splicing variations in human tissues and cancer

Nucleic Acids Research(2023)10.1093/nar/gkad1043
Top 36%
0.548DataRank
Top 36%20 citations

San Jewell, Kristen W. Lynch, Andrei Thomas‐Tikhonenko, Yoseph Barash, Mathieu Quesnel-Vallières

Papers

Driven by 29 papers — median percentile 64. Top paper: “Targeting CD123 in blastic plasmacytoid dendritic cell neoplasm using allogeneic anti-CD123 CAR T cells”.

Targeting CD123 in blastic plasmacytoid dendritic cell neoplasm using allogeneic anti-CD123 CAR T cells

Nature Communications(2022)10.1038/s41467-022-29669-8
N/A
1.3DataRank · unranked
43 citations

Agnès Gouble, Kathryn L. Black, Anna Skwarska, Ammar S. Naqvi, Deanne Taylor +28 more

IFITM3 functions as a PIP3 scaffold to amplify PI3K signalling in B cells

Nature(2020)10.1038/s41586-020-2884-6
N/A
0.717DataRank · unranked
118 citations

Mark E. Robinson, Ning Ma, Dewan Artadji, Mohamed A. Ahmed, Gang Xiao +24 more

Retention of CD19 intron 2 contributes to CART-19 resistance in leukemias with subclonal frameshift mutations in CD19

Leukemia(2020)10.1038/s41375-019-0580-z
N/A
0.716DataRank · unranked
117 citations

Katharina E. Hayer, Ammar S. Naqvi, Sisi Zheng, Scarlett Y. Yang, Derek Oldridge +14 more

High-throughput mutagenesis identifies mutations and RNA-binding proteins controlling CD19 splicing and CART-19 therapy resistance

Nature Communications(2022)10.1038/s41467-022-31818-y
N/A
0.614DataRank · unranked
59 citations

Laura Schulz, Mihaela Enculescu, Claudia Paret, Bea Spiekermann, Mathieu Quesnel-Vallières +16 more

Myc-Transformed Epithelial Cells Down-Regulate Clusterin, Which Inhibits Their Growth in Vitro and Carcinogenesis in Vivo

Cancer Research(2004)10.1158/0008-5472.can-03-1953
N/A
0.598DataRank · unranked
53 citations

Isabelle Viard-Leveugle, Michael Dews, Philippe Wehrli, Cinzia Sevignani, Duonan Yu +11 more

Identifying common transcriptome signatures of cancer by interpreting deep learning models

Genome biology(2022)10.1186/s13059-022-02681-3
N/A
0.553DataRank · unranked
39 citations

Mathieu Quesnel-Vallières, David Wang, Andrei Thomas‐Tikhonenko, Kristen W. Lynch, Yoseph Barash +1 more

MAJIQlopedia: an encyclopedia of RNA splicing variations in human tissues and cancer

Nucleic Acids Research(2023)10.1093/nar/gkad1043
Top 36%
0.548DataRank
Top 36%20 citations

San Jewell, Kristen W. Lynch, Andrei Thomas‐Tikhonenko, Yoseph Barash, Mathieu Quesnel-Vallières

RNA-binding proteins of COSMIC importance in cancer

Journal of Clinical Investigation(2021)10.1172/jci151627
N/A
0.524DataRank · unranked
32 citations

Andrei Thomas‐Tikhonenko, Peter S. Choi

Contrasting and combining transcriptome complexity captured by short and long RNA sequencing reads

Genome Research(2024)10.1101/gr.278659.123
N/A
0.442DataRank · unranked
18 citations

San Jewell, Andrei Thomas‐Tikhonenko, Yoseph Barash, Seong Woo Han

Discovery of antibodies targeting multipass transmembrane proteins using a suspension cell-based evolutionary approach

Cell Reports Methods(2023)10.1016/j.crmeth.2023.100429
N/A
0.442DataRank · unranked
18 citations

Justyn Fine, Yang Hui-lin, Derek VanDyke, Zhiwei Ang, Kook Bum Kim +3 more

An Alternatively Spliced Gain-of-Function NT5C2 Isoform Contributes to Chemoresistance in Acute Lymphoblastic Leukemia

Cancer Research(2024)10.1158/0008-5472.can-23-3804
N/A
0.428DataRank · unranked
10 citations

Clara Reglero, Catherine D. Falkenstein, Annette Castro, Katharina E. Hayer, Caleb M. Radens +9 more

FBXW7β isoform drives transcriptional activation of the proinflammatory TNF cluster in human pro-B cells

Blood Advances(2022)10.1182/bloodadvances.2022007910
N/A
0.345DataRank · unranked
9 citations

Katharina E. Hayer, Hossein Fazelinia, Lynn A. Spruce, Mukta Asnani, Kathryn L. Black +6 more

Contrasting and Combining Transcriptome Complexity Captured by Short and Long RNA Sequencing Reads

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.21.568046
N/A
0.208DataRank · unranked
3 citations

San Jewell, Andrei Thomas‐Tikhonenko, Yoseph Barash, Seong Woo Han

A convergent malignant phenotype in B-cell acute lymphoblastic leukemia involving the splicing factor SRRM1

NAR Cancer(2022)10.1093/narcan/zcac041
N/A
0DataRank · unranked
13 citations

Marina Reixachs‐Solé, Antonio C. Fuentes-Fayos, Katharina E. Hayer, Juan L. Melero, Fabienne R. S. Adriaanse +11 more

Loss of AID exacerbates the malignant progression of CLL

Leukemia(2022)10.1038/s41375-022-01663-5
N/A
0DataRank · unranked
1 citations

Sai Ravi Pingali, Javier Pinilla‐Ibarz, Michael L. Atchison, Constantinos Koumenis, Yair Argon +5 more

Alternative splicing of its 5′-UTR limits CD20 mRNA translation and enables resistance to CD20-directed immunotherapies

Blood(2023)10.1182/blood.2023020400
N/A
0DataRank · unranked
47 citations

Luca Paruzzo, Katharina E. Hayer, Carolin Schmidt, Manuel Torres-Diz, Feng Xu +19 more

MYC Hyperactivates Wnt Signaling in APC / CTNNB1 -Mutated Colorectal Cancer Cells through miR-92a–Dependent Repression of DKK3

Molecular Cancer Research(2021)10.1158/1541-7786.mcr-21-0666
N/A
0DataRank · unranked
23 citations

Claudia Lanauze, Xin Wang, Katharina E. Hayer, Manuel Torres-Diz, N. Adrian Leu +5 more

A Bayesian model for unsupervised detection of RNA splicing based subtypes in cancers

Nature Communications(2023)10.1038/s41467-022-35369-0
N/A
0DataRank · unranked
9 citations

Mathieu Quesnel-Vallières, San Jewell, Moein Elzubeir, Kristen W. Lynch, Andrei Thomas‐Tikhonenko +2 more

Alternative splicing of its 5’-UTR limits CD20 mRNA translation and enables resistance to CD20-directed immunotherapies

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.19.529123
N/A
0DataRank · unranked
5 citations

Luca Paruzzo, Katharina E. Hayer, Carolin Schmidt, Manuel Torres-Diz, Feng Xu +19 more

Data from p53-Responsive miR-194 Inhibits Thrombospondin-1 and Promotes Angiogenesis in Colon Cancers

(2023)10.1158/0008-5472.c.6503210.v1
N/A
0DataRank · unranked
0 citations

Stacy Hultine, Lauren M. Smith, Michael Dews, Jamie L. Fox, Dauren Biyashev +6 more

An Alternatively Spliced Gain-of-Function NT5C2 Isoform Contributes to Chemoresistance in Acute Lymphoblastic Leukemia

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.14.557413
N/A
0DataRank · unranked
0 citations

Clara Reglero, Catherine D. Falkenstein, Annette Castro, Katharina E. Hayer, Caleb M. Radens +9 more

Steering research on mRNA splicing in cancer towards clinical translation

Nature reviews. Cancer(2024)10.1038/s41568-024-00750-2
N/A
0DataRank · unranked
40 citations

Frédéric H.‐T. Allain, Brittany Angarola, Douglas L. Black, Angela N. Brooks, Chonghui Cheng +14 more

NRCAM variant defined by microexon skipping is a targetable cell surface proteoform in high-grade gliomas

Cell Reports(2025)10.1016/j.celrep.2025.116099
N/A
0DataRank · unranked
5 citations

Ammar S. Naqvi, Makenna Higgins, Jia‐Geng Liu, Kyra Harvey, Julien Jarroux +25 more

Identifying common transcriptome signatures of cancer by interpreting deep learning models

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.11.467790
N/A
0DataRank · unranked
3 citations

Mathieu Quesnel-Vallières, Andrei Thomas‐Tikhonenko, Kristen W. Lynch, Yoseph Barash, Anupama Jha

Tilting MYC toward cancer cell death

Trends in cancer(2021)10.1016/j.trecan.2021.08.002
N/A
0DataRank · unranked
63 citations

Elena Sotillo, Chi V. Dang, Andrei Thomas‐Tikhonenko, Colleen T. Harrington

MYC hyperactivates WNT signaling in APC/CTNNB1-mutated colorectal cancer cells through miR-92a-dependent repression of DKK3

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.26.453875
N/A
0DataRank · unranked
0 citations

Claudia Lanauze, Xin Wang, Katharina E. Hayer, Manuel Torres-Diz, Yogev Sela +4 more

Direct long-read RNA sequencing identifies a subset of questionable exitrons likely arising from reverse transcription artifacts

Genome biology(2021)10.1186/s13059-021-02411-1
N/A
0DataRank · unranked
40 citations

Manuel Torres-Diz, Mariela Cortés-López, Katharina E. Hayer, Mukta Asnani, Sarah K. Tasian +6 more

Colorectal Cancer-Associated Smad4 R361 Hotspot Mutations Boost Wnt/β-Catenin Signaling through Enhanced Smad4–LEF1 Binding

Molecular Cancer Research(2021)10.1158/1541-7786.mcr-20-0721
N/A
0DataRank · unranked
17 citations

Priyanka Sehgal, Katharina E. Hayer, Manuel Torres-Diz, James A. Pippin, Struan F.A. Grant +2 more

Modulation of CD22 Protein Expression in Childhood Leukemia by Pervasive Splicing Aberrations: Implications for CD22-Directed Immunotherapies

Blood Cancer Discovery(2021)10.1158/2643-3230.bcd-21-0087
N/A
0DataRank · unranked
63 citations

Elisabeth Gillespie, Ammar S. Naqvi, Katharina E. Hayer, Zhiwei Ang, Manuel Torres-Diz +17 more