Robert J. Wilkinson

Also affiliated with Wellcome Centre for Infectious Diseases Research in Africa, Imperial College London

Medicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 2%percentile

3.0Author DataRank

Indexed papers

5in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 5 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Mortality from drug-resistant tuberculosis in high-burden countries comparing routine drug susceptibility testing with whole-genome sequencing: a multicentre cohort study

The Lancet Microbe(2021)10.1016/s2666-5247(21)00044-6

Top 10%

2.1DataRank

Top 10%48 citations

Martina L. Reichmuth, Marie Ballif, Chloé Loiseau, Sònia Borrell, Miriam Reinhard +17 more

Papers

Driven by 114 papers — median percentile 66. Top paper: “Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: the CAPTURE study”.

Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: the CAPTURE study

Nature Cancer(2021)10.1038/s43018-021-00274-w

N/A

6.8DataRank · unranked

185 citations

Scott T.C. Shepherd, Lewis Au, Katalin A. Wilkinson, Mary Wu, Fiona Byrne +91 more

Mortality from drug-resistant tuberculosis in high-burden countries comparing routine drug susceptibility testing with whole-genome sequencing: a multicentre cohort study

The Lancet Microbe(2021)10.1016/s2666-5247(21)00044-6

Top 10%

2.1DataRank

Top 10%48 citations

Martina L. Reichmuth, Marie Ballif, Chloé Loiseau, Sònia Borrell, Miriam Reinhard +17 more

Intensified tuberculosis treatment to reduce the mortality of HIV-infected and uninfected patients with tuberculosis meningitis (INTENSE-TBM): study protocol for a phase III randomized controlled trial

Trials(2022)10.1186/s13063-022-06772-1

N/A

1.3DataRank · unranked

40 citations

Maryline Bonnet, Alexandra Calmy, Mihaja Raberahona, Rivonirina Andry Rakotoarivelo, Niaina Rakotosamimanana +16 more

BACH1 promotes tissue necrosis and Mycobacterium tuberculosis susceptibility

Nature Microbiology(2023)10.1038/s41564-023-01523-7

N/A

1.2DataRank · unranked

53 citations

Sivaranjani Namasivayam, Artur T. L. Queiroz, Eduardo R. Fukutani, Kerry L. Hilligan, Kate Aberman +21 more

Functional immune responses against SARS-CoV-2 variants of concern after fourth COVID-19 vaccine dose or infection in patients with blood cancer

Cell Reports Medicine(2022)10.1016/j.xcrm.2022.100781

N/A

1.1DataRank · unranked

26 citations

Scott T.C. Shepherd, Lewis Au, Mary Wu, Ruth Harvey, Katalin A. Wilkinson +59 more

Tuberculosis and Type 2 Diabetes Mellitus: An Inflammatory Danger Signal in the Time of Coronavirus Disease 2019

Clinical Infectious Diseases(2020)10.1093/cid/ciaa747

N/A

1.0DataRank · unranked

15 citations

Robert J. Wilkinson

T cell responses to SARS-CoV-2 spike cross-recognize Omicron

Nature(2022)10.1038/s41586-022-04460-3

N/A

0.966DataRank · unranked

625 citations

Marius B. Tincho, Amkele Ngomti, Richard Baguma, Ntombi Benede, Akiko Suzuki +42 more

The Immune Response toMycobacterium tuberculosisin HIV-1-Coinfected Persons

Annual Review of Immunology(2018)10.1146/annurev-immunol-042617-053420

N/A

0.725DataRank · unranked

125 citations

Catherine Riou, Elsa du Bruyn, Rachel Pei-Jen Lai, Yolande X.R. Harley, Graeme Meintjes +3 more

Selection Analysis Identifies Clusters of Unusual Mutational Changes in Omicron Lineage BA.1 That Likely Impact Spike Function

Molecular Biology and Evolution(2022)10.1093/molbev/msac061

N/A

0.723DataRank · unranked

123 citations

Spyros Lytras, Alexander G. Lucaci, Wolfgang Maier, Björn Grüning, Stephen D. Shank +33 more

Dysregulation of the Immune Environment in the Airways During HIV Infection

Frontiers in Immunology(2021)10.3389/fimmu.2021.707355

N/A

0.716DataRank · unranked

13 citations

Andreia Soares, Narjis Thawer, Tracey L. Müller, Agano Kiravu, Zekarias Ginbot +9 more

Modern Lineages of Mycobacterium tuberculosis Exhibit Lineage-Specific Patterns of Growth and Cytokine Induction in Human Monocyte-Derived Macrophages

PLoS ONE(2012)10.1371/journal.pone.0043170

N/A

0.672DataRank · unranked

87 citations

Laura Lenders, Katalin A. Wilkinson, Robert J. Wilkinson, Mark P. Nicol, Rajesh Sarkar

Development of a fixed module repertoire for the analysis and interpretation of blood transcriptome data

Nature Communications(2021)10.1038/s41467-021-24584-w

N/A

0.657DataRank · unranked

79 citations

Darawan Rinchai, Nicole Baldwin, Mohammed Toufiq, Elizabeth Whalen, Mathieu Garand +28 more

SARS-CoV-2 spike T cell responses induced upon vaccination or infection remain robust against Omicron

medRxiv(2021)10.1101/2021.12.26.21268380

N/A

0.644DataRank · unranked

72 citations

Marius B. Tincho, Amkele Ngomti, Richard Baguma, Ntombi Benede, Akiko Suzuki +37 more

Comprehensive plasma proteomic profiling reveals biomarkers for active tuberculosis

JCI Insight(2020)10.1172/jci.insight.137427

N/A

0.628DataRank · unranked

65 citations

Cory White, Naomi F. Walker, Marc Tebruegge, Hannah F. Schiff, César Ugarte‐Gil +12 more

Mycobacterium tuberculosis-specific CD4 T cells expressing CD153 inversely associate with bacterial load and disease severity in human tuberculosis

Mucosal Immunology(2020)10.1038/s41385-020-0322-6

N/A

0.617DataRank · unranked

60 citations

Sheena Ruzive, Cecilia S. Lindestam Arlehamn, Alessandro Sette, Alan Sher, Daniel L. Barber +3 more

Disease extent and anti‐tubercular treatment response correlates with Mycobacterium tuberculosis‐specific CD4 T‐cell phenotype regardless of HIV‐1 status

Clinical & Translational Immunology(2020)10.1002/cti2.1176

N/A

0.593DataRank · unranked

51 citations

Elsa Du Bruyn, Sheena Ruzive, René Goliath, Cecilia S. Lindestam Arlehamn, Alessandro Sette +4 more

An observational study identifying highly tuberculosis-exposed, HIV-1-positive but persistently TB, tuberculin and IGRA negative persons with M. tuberculosis specific antibodies in Cape Town, South Africa

EBioMedicine(2020)10.1016/j.ebiom.2020.103053

N/A

0.578DataRank · unranked

46 citations

Craig Kinnear, Marianna Orlova, Stephanie Fischinger, Sally Shin, Sihaam Boolay +8 more

Addressing pandemic-wide systematic errors in the SARS-CoV-2 phylogeny

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.29.591666

Top 34%

0.575DataRank

Top 34%17 citations

Angie S. Hinrichs, D.P. Anderson, Lily Karim, Bethany L. Dearlove, Jeff Knaggs +95 more

Baseline IL-6 is a biomarker for unfavourable tuberculosis treatment outcomes: a multisite discovery and validation study

European Respiratory Journal(2021)10.1183/13993003.00905-2021

N/A

0.568DataRank · unranked

43 citations

Pavan Kumar, Mariana Araújo‐Pereira, Vandana Kulkarni, Mandar Paradkar, Neeta Pradhan +19 more

Radiological and functional evidence of the bronchial spread of tuberculosis: an observational analysis

The Lancet Microbe(2021)10.1016/s2666-5247(21)00058-6

N/A

0.561DataRank · unranked

41 citations

Xiang Yu, Bronwyn Smith, Xin Liu, Jingcai Gao, Andreas H. Diacon +18 more

Study protocol for a phase 2A trial of the safety and tolerability of increased dose rifampicin and adjunctive linezolid, with or without aspirin, for HIV-associated tuberculous meningitis [LASER-TBM]

Wellcome Open Research(2021)10.12688/wellcomeopenres.16783.1

N/A

0.554DataRank · unranked

13 citations

Sean Wasserman, Mpumi Maxebengula, Cari Stek, Marise Bremer, Remy Daroowala +33 more

Back-to-Africa introductions of Mycobacterium tuberculosis as the main cause of tuberculosis in Dar es Salaam, Tanzania

PLoS Pathogens(2023)10.1371/journal.ppat.1010893

N/A

0.551DataRank · unranked

27 citations

Liliana K. Rutaihwa, Etthel M. Windels, Jerry Hella, Fabrizio Menardo, Mohamed Sasamalo +39 more

Visualizing the dynamics of tuberculosis pathology using molecular imaging

Journal of Clinical Investigation(2021)10.1172/jci145107

N/A

0.520DataRank · unranked

31 citations

Elizabeth W. Tucker, Carolyn J. Anderson, Claire L. Carter, Shashank Ganatra, Deepak Kaushal +13 more

Assessing the clinical severity of the Omicron variant in the Western Cape Province, South Africa, using the diagnostic PCR proxy marker of RdRp target delay to distinguish between Omicron and Delta infections – a survival analysis

International Journal of Infectious Diseases(2022)10.1016/j.ijid.2022.02.051

N/A

0.489DataRank · unranked

25 citations

Mary‐Ann Davies, Alexa Heekes, Carolyn Williamson, Ziyaad Valley‐Omar, Diana Hardie +21 more

Advancing the chemotherapy of tuberculous meningitis: a consensus view

The Lancet Infectious Diseases(2024)10.1016/s1473-3099(24)00512-7

N/A

0.489DataRank · unranked

25 citations

Joseph Donovan, Evelyne Kestelyn, James A Watson, R.E. Aarnoutse, James Barnacle +27 more

Cognitive Impairment in Tuberculous Meningitis

Clinical Infectious Diseases(2022)10.1093/cid/ciac831

N/A

0.483DataRank · unranked

24 citations

Anna J. Dreyer, Christine Albertyn, Mpumi Maxebengula, Cari Stek, Sean Wasserman +7 more

Kaposi’s Sarcoma-Associated Herpesvirus, but Not Epstein-Barr Virus, Co-infection Associates With Coronavirus Disease 2019 Severity and Outcome in South African Patients

Frontiers in Microbiology(2022)10.3389/fmicb.2021.795555

N/A

0.464DataRank · unranked

21 citations

Humaira Lambarey, Abeen Chetram, Catherine Riou, Robert J. Wilkinson, Georgia Schäfer +1 more

Inflammatory profile of patients with tuberculosis with or without HIV-1 co-infection: a prospective cohort study and immunological network analysis

The Lancet Microbe(2021)10.1016/s2666-5247(21)00037-9

N/A

0.457DataRank · unranked

20 citations

Kiyoshi F. Fukutani, Neesha Rockwood, Charlotte Schutz, Graeme Meintjes, María B. Arriaga +8 more

High resolution imaging and five-year tuberculosis contact outcomes

medRxiv(2023)10.1101/2023.07.03.23292111

N/A

0.449DataRank · unranked

19 citations

Anna K. Coussens, Friedrich Thienemann, Bianca Sossen, Sandra Mukasa, James Warwick +31 more

Serial measurement of M. tuberculosis in blood from critically-ill patients with HIV-associated tuberculosis

EBioMedicine(2022)10.1016/j.ebiom.2022.103949

N/A

0.449DataRank · unranked

19 citations

Charlotte Schutz, Avuyonke Balfour, Muki Shey, Mireille Kamariza, Carolyn R. Bertozzi +13 more

Host Directed Therapies for Tuberculous Meningitis

Wellcome Open Research(2020)10.12688/wellcomeopenres.16474.1

N/A

0.416DataRank · unranked

15 citations

Joseph Donovan, Marise Bremer, Ronald van Toorn, Johan F. Schoeman, Ariba Dadabhoy +8 more

Profile of SARS-CoV-2-specific CD4 T cell response: Relationship with disease severity and impact of HIV-1 and active Mycobacterium tuberculosis co-infection

medRxiv(2021)10.1101/2021.02.16.21251838

N/A

0.373DataRank · unranked

11 citations

Elsa Du Bruyn, Cari Stek, Remy Daroowala, René Goliath, Fatima Abrahams +9 more

TBDBT: A TB DataBase Template for collection of harmonized TB clinical research data in REDCap, facilitating data standardisation for inter-study comparison and meta-analyses

PLoS ONE(2021)10.1371/journal.pone.0249165

Top 51%

0.343DataRank

Top 51%8 citations

Amanda Jackson, Jon Ambler, Katherine Johnston, Elsa Du Bruyn, Charlotte Schultz +7 more

Host transcriptomic signatures of tuberculosis can predict immune reconstitution inflammatory syndrome in HIV patients

European Journal of Immunology(2022)10.1002/eji.202249815

N/A

0.330DataRank · unranked

8 citations

Hannah Painter, Adam Penn‐Nicholson, Asma Toefy, Mzwandile Erasmus, Willem A. Hanekom +11 more

Neutrophil extracellular trap formation and gene programs distinguish TST/IGRA sensitization outcomes among Mycobacterium tuberculosis exposed persons living with HIV

PLoS Genetics(2023)10.1371/journal.pgen.1010888

N/A

0.330DataRank · unranked

8 citations

Wilian Correa-Macedo, Rachel Evans, Allison Seeger, Lize Engelbrecht, Jurgen Kriel +12 more

Rapid, simplified whole blood-based multiparameter assay to quantify and phenotype SARS-CoV-2 specific T cells

medRxiv(2020)10.1101/2020.10.30.20223099

N/A

0.312DataRank · unranked

7 citations

Georgia Schäfer, Elsa Du Bruyn, René Goliath, Cari Stek, Huihui Mou +4 more

Characterization of Mycobacterium tuberculosis –Specific Th22 Cells and the Effect of Tuberculosis Disease and HIV Coinfection

The Journal of Immunology(2022)10.4049/jimmunol.2200140

N/A

0.312DataRank · unranked

7 citations

Millicent A. Omondi, Rubina Bunjun, Robert J. Wilkinson, Catherine Riou, Wendy A. Burgers +1 more

Treatment of tuberculous meningitis: Overdue for concerted action

Tuberculosis(2023)10.1016/j.tube.2023.102361

N/A

0.241DataRank · unranked

4 citations

Joseph Donovan, Guy Thwaites, Reinout van Crevel, Sean Wasserman, Robert J. Wilkinson

Virus-Shaped Mesoporous Silica Nanostars to Improve the Transport of Drugs across the Blood–Brain Barrier

ACS Applied Materials & Interfaces(2024)10.1021/acsami.4c06726

N/A

0.241DataRank · unranked

4 citations

Ieva Ragaisyte, William Morton, Stefano Angioletti‐Uberti, Alizé Proust, Rocco D’Antuono +12 more

Association Between Mycobacterium tuberculosis Sensitization and Insulin Resistance Among US Adults Screened for Type 2 Diabetes Mellitus

Open Forum Infectious Diseases(2024)10.1093/ofid/ofae568

N/A

0.208DataRank · unranked

3 citations

Aloice O. Aluoch, Brian Claggett, Moffat Nyirenda, Mark J. Siedner, Katalin A. Wilkinson +3 more

A human YEATS4 variant confers resistance to TST and IGRA conversion despite Mycobacterium tuberculosis exposure

Genome Medicine(2025)10.1186/s13073-025-01547-0

N/A

0.165DataRank · unranked

2 citations

Jonathan Bohlen, Elouise E. Kroon, Marc Antoine Jean‐Juste, Jérémy Manry, Matthieu Chaldebas +27 more

Profile of Mycobacterium tuberculosis -specific CD4 T cells at the site of disease and blood in pericardial tuberculosis

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.12.491749

N/A

0.165DataRank · unranked

2 citations

Sheena Ruzive, Patrick Howlett, Ashley J. Jacobs, Cecilia S. Lindestam Arlehamn, Alessandro Sette +8 more

Discordance between measures of Mycobacterium tuberculosis sensitization and type 2 diabetes mellitus in the United States (NHANES): A population-based cohort study

Journal of Infection(2025)10.1016/j.jinf.2025.106496

N/A

0.104DataRank · unranked

1 citations

Katalin A. Wilkinson, Brian Claggett, Ntobeko A. B. Ntusi, Mark J. Siedner, Robert J. Wilkinson +1 more

Back-to-Africa introductions of Mycobacterium tuberculosis as the main cause of tuberculosis in Dar es Salaam, Tanzania

medRxiv(2022)10.1101/2022.09.29.22280296

N/A

0.104DataRank · unranked

1 citations

Liliana K. Rutaihwa, Etthel M. Windels, Jerry Hella, Fabrizio Menardo, Mohamed Sasamalo +37 more

Addition to “Nanostars Carrying Multifunctional Neurotrophic Dendrimers Protect Neurons in Preclinical In Vitro Models of Neurodegenerative Disorders”

ACS Applied Materials & Interfaces(2023)10.1021/acsami.3c02300

N/A

0.104DataRank · unranked

1 citations

Stanislava Pankratova, Pedro Machado, Nathalie Fernando, Anna Regoutz, Federica Talamona +8 more

Cardiometabolic Biomarkers and Systemic Inflammation in US Adolescents and Young Adults With Latent Tuberculosis Infection: A Population-Based Cohort Study

Open Forum Infectious Diseases(2025)10.1093/ofid/ofaf194

N/A

0.104DataRank · unranked

1 citations

Ntobeko A. B. Ntusi, Jennifer Jao, Heather J. Zar, Brian Claggett, Mark J. Siedner +3 more

A Nanopore Sequencing-based Pharmacogenomic Panel to Personalize Tuberculosis Drug Dosing

American Journal of Respiratory and Critical Care Medicine(2024)10.1164/rccm.202309-1583oc

N/A

0DataRank · unranked

21 citations

Késia Esther da Silva, Neesha Rockwood, Roeland E. Wasmann, Nombuso Yende, Taeksun Song +5 more

Integrated plasma proteomics identifies tuberculosis-specific diagnostic biomarkers

JCI Insight(2024)10.1172/jci.insight.173273

N/A

0DataRank · unranked

20 citations

Naomi F. Walker, César Ugarte‐Gil, Marc Tebruegge, Antigoni Manousopoulou, Spiros D. Garbis +12 more

Elevated Plasma Matrix Metalloproteinases Are Associated With Mycobacterium tuberculosis Bloodstream Infection and Mortality in Human Immunodeficiency Virus–Associated Tuberculosis

The Journal of Infectious Diseases(2024)10.1093/infdis/jiae296

N/A

0DataRank · unranked

5 citations

Charlotte Schutz, Amy Ward, David Barr, Charles Opondo, Muki Shey +5 more

HLA-E/Mtb specific CD4+ and CD8+ T cells have a memory phenotype in individuals with TB infection

Frontiers in Immunology(2024)10.3389/fimmu.2024.1505329

N/A

0DataRank · unranked

3 citations

Catherine Riou, Thomas J. Scriba, Marjolein van Wolfswinkel, Krista E. van Meijgaarden, Kees L. M. C. Franken +4 more

SARS-CoV-2 seroepidemiology in Cape Town, South Africa, and implications for future outbreaks in low-income communities

PLOS Global Public Health(2024)10.1371/journal.pgph.0003554

N/A

0DataRank · unranked

1 citations

Helena Vreede, Mary‐Ann Davies, Alexa Heekes, Emma Kalk, Diana Hardie +19 more

PET/CT guided tuberculosis treatment shortening: a randomized trial

medRxiv(2024)10.1101/2024.10.03.24314723

N/A

0DataRank · unranked

10 citations

Ray Y. Chen, Xiang Yu, Bronwyn Smith, Xin Liu, Jingcai Gao +50 more

Latent tuberculosis infection and incident cardiovascular and non-cardiovascular death

medRxiv(2024)10.1101/2024.03.11.24304070

N/A

0DataRank · unranked

1 citations

Katalina A Wilkinson, Brian Claggett, Aloice O. Aluoch, Mark J. Siedner, Mpiko Ntsekhe +4 more

Pharmacokinetics of antitubercular drugs in patients hospitalized with HIV-associated tuberculosis: a population modeling analysis

Wellcome Open Research(2024)10.12688/wellcomeopenres.17660.3

N/A

0DataRank · unranked

0 citations

Maxwell Chirehwa, Charlotte Schutz, David Barr, Amy Ward, Saskia Janssen +9 more

Effect of prior tuberculosis on cardiovascular status in perinatally HIV-1-infected adolescents

medRxiv(2024)10.1101/2024.03.09.24303989

N/A

0DataRank · unranked

0 citations

Carlos‐Eduardo Guerrero‐Chalela, Landon Myer, Jennifer Jao, Mpiko Ntsekhe, Katalin A. Wilkinson +4 more

Association of prior tuberculosis with cardiovascular status in perinatally HIV-1-infected adolescents

Open Heart(2024)10.1136/openhrt-2024-002960

N/A

0DataRank · unranked

0 citations

Carlos‐Eduardo Guerrero‐Chalela, Emma Carkeek, Nana Akua Asafu‐Agyei, Nomawethu Jele, Lisa Frigati +8 more

Population Pharmacokinetics of Rifampicin in Plasma and Cerebrospinal Fluid in Adults With Tuberculosis Meningitis

The Journal of Infectious Diseases(2025)10.1093/infdis/jiaf178

N/A

0DataRank · unranked

9 citations

Sean Wasserman, Kamunkhwala Gausi, Angharad Davis, Cari Stek, Lubbe Wiesner +4 more

Clinical, metabolic, and immune interaction between tuberculosis and diabetes mellitus: implications and opportunities for therapies

Expert Opinion on Pharmacotherapy(2025)10.1080/14656566.2025.2508904

N/A

0DataRank · unranked

8 citations

Leigh A. Kotzé, Cari Stek, A. Brian West, Antoine Roux, Nadja Sobratee +7 more

Anti-PD-1 immunotherapy leads to tuberculosis reactivation via dysregulation of TNF-α

eLife(2020)10.7554/elife.52668

N/A

0DataRank · unranked

130 citations

Magdalena K. Bielecka, Paul Ogongo, Naomi F. Walker, Matthew J. Ellis, Diana J. Garay‐Baquero +14 more

Population pharmacokinetics of pyrazinamide and isoniazid in plasma and cerebrospinal fluid from South African adults with tuberculous meningitis

Antimicrobial Agents and Chemotherapy(2025)10.1128/aac.00099-25

N/A

0DataRank · unranked

3 citations

Sean Wasserman, Juan Eduardo Reséndiz‐Galván, Noha Abdelgawad, Angharad Davis, Cari Stek +4 more

The association of class II HLA alleles with tuberculosis-associated immune reconstitution inflammatory syndrome

PLoS Pathogens(2025)10.1371/journal.ppat.1013497

N/A

0DataRank · unranked

1 citations

Sarah Pedretti, Tafadzwa Chimbetete, Rama Gangula, Muki Shey, Cari Stek +6 more

Pharmacokinetics of Dexamethasone in Tuberculous Meningitis

Clinical Infectious Diseases(2025)10.1093/cid/ciaf642

N/A

0DataRank · unranked

1 citations

Juan Eduardo Reséndiz‐Galván, Noha Abdelgawad, Angharad Davis, Cari Stek, Lubbe Wiesner +5 more

Transcript-Capture sequencing enriches mRNA of Mycobacterium tuberculosis from host samples

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.28.685133

N/A

0DataRank · unranked

2 citations

Richard M. Jones, Jessica Assadi, Robert Morrison, Taeksun Song, Xiang Yu +8 more

Implementation of a genotyped African population cohort, with virtual follow-up: A feasibility study in the Western Cape Province, South Africa

Wellcome Open Research(2025)10.12688/wellcomeopenres.23009.2

N/A

0DataRank · unranked

0 citations

Anna K. Coussens, Maleeka Abrahams, Melissa J. Blumenthal, Francisco Lakay, Robert J. Wilkinson +5 more

Predicting trajectories of acute illness using RNA velocity of whole blood

Research Square(2025)10.21203/rs.3.rs-5764288/v1

N/A

0DataRank · unranked

0 citations

Clare Wilson, Dominic Habgood-Coote, Suzanna Patterson, Mahdad Noursadeghi, Raymond M Moseki +50 more

Protein Kinase C δ: a critical hub regulating macrophage immunomodulatory functions during Mycobacterium tuberculosis infection

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.19.653976

N/A

0DataRank · unranked

0 citations

Mumin Ozturk, Nashied Peton, Tariq Ganief, Sibongiseni KL Poswayo, Robert P. Rousseau +13 more

Pharmacokinetics of dexamethasone in tuberculosis meningitis

medRxiv(2025)10.1101/2025.07.14.25331510

N/A

0DataRank · unranked

0 citations

Juan Eduardo Reséndiz‐Galván, Noha Abdelgawad, Angharad Davis, Cari Stek, Lubbe Wiesner +5 more

Optimisation and application of a T-cell antigen-specific activation assay as diagnostic and treatment-monitoring tool for tuberculosis

ERJ Open Research(2025)10.1183/23120541.01016-2025

N/A

0DataRank · unranked

0 citations

Elisa Nemes, Michèle Tameris, Simon C. Mendelsohn, Michelle Fisher, Elizabeth Filander +15 more

Taurine transport is a critical modulator of ionic fluxes during NLRP3 inflammasome activation

Cell Reports(2025)10.1016/j.celrep.2025.116317

N/A

0DataRank · unranked

8 citations

Joohee Kim, Kamil Skirlo, Trevor J. Ferris, Jack Green, Cari Stek +17 more

Early antituberculosis drug exposure in hospitalized patients with human immunodeficiency virus‐associated tuberculosis

British Journal of Clinical Pharmacology(2020)10.1111/bcp.14207

N/A

0DataRank · unranked

19 citations

Maxwell Chirehwa, David Barr, Amy Ward, Saskia Janssen, Rosie Burton +8 more

HIV Coinfection Is Associated with Low-Fitness rpoB Variants in Rifampicin-Resistant Mycobacterium tuberculosis

Antimicrobial Agents and Chemotherapy(2020)10.1128/aac.00782-20

N/A

0DataRank · unranked

13 citations

Daniela Brites, Miriam Reinhard, Kathrin Zürcher, Sònia Borrell, Marie Ballif +16 more

“SILVAMP TB LAM” Rapid Urine Tuberculosis Test Predicts Mortality in Patients Hospitalized With Human Immunodeficiency Virus in South Africa

Clinical Infectious Diseases(2020)10.1093/cid/ciaa024

N/A

0DataRank · unranked

13 citations

Tobias Broger, Andrew D. Kerkhoff, Charlotte Schutz, André Trollip, Emmanuel Moreau +9 more

Standardized approaches for clinical sampling and endpoint ascertainment in tuberculous meningitis studies

Wellcome Open Research(2020)10.12688/wellcomeopenres.15497.2

N/A

0DataRank · unranked

12 citations

Felicia C. Chow, Sean Wasserman, Sofiati Dian, Rachel Lai, Lidya Chaidir +6 more

Natural Polymorphisms in Mycobacterium tuberculosis Conferring Resistance to Delamanid in Drug-Naive Patients

Antimicrobial Agents and Chemotherapy(2020)10.1128/aac.00513-20

N/A

0DataRank · unranked

24 citations

Rico Hömke, Kathrin Zürcher, Peter Sander, Anchalee Avihingsanon, Jimena Collantes +11 more

Recent Developments in Tuberculous Meningitis Pathogenesis and Diagnostics

Wellcome Open Research(2020)10.12688/wellcomeopenres.15506.2

N/A

0DataRank · unranked

6 citations

Angharad Davis, Kusum Sharma, Robindra Basu Roy, Ahmad Rizal Ganiem, Enock Kagimu +5 more

An observational study identifying highly tuberculosis-exposed, HIV-1-positive but persistently TB, tuberculin and IGRA negative persons with M. tuberculosis specific antibodies in Cape Town, South Africa

medRxiv(2020)10.1101/2020.07.07.20147967

N/A

0DataRank · unranked

2 citations

Craig Kinnear, Marianna Orlova, Stephanie Fischinger, Sally Shin, Sihaam Boolay +8 more

Natural Polymorphisms in Mycobacterium tuberculosis Conferring Resistance to Delamanid in Drug-naïve Patients

medRxiv(2020)10.1101/2020.08.07.20167130

N/A

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2 citations

Rico Hoemke, Kathrin Zürcher, Peter Sander, Anchalee Avihingsanon, Jimena Collantes +11 more

HIV coinfection is associated with low fitness rpoB variants in rifampicin-resistant Mycobacterium tuberculosis

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.20.208835

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0DataRank · unranked

0 citations

Daniela Brites, Miriam Reinhard, Kathrin Zürcher, Sònia Borrell, Marie Ballif +16 more

Characterization of Mycobacterium tuberculosis -specific Th22 cells and the effect of tuberculosis disease and HIV co-infection

medRxiv(2020)10.1101/2020.10.22.20217521

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0DataRank · unranked

0 citations

F. Millicent A. Omondi, Rubina Bunjun, Robert J. Wilkinson, Catherine Riou, Wendy A. Burgers +1 more

Relationship of SARS-CoV-2–specific CD4 response to COVID-19 severity and impact of HIV-1 and tuberculosis coinfection

Journal of Clinical Investigation(2021)10.1172/jci149125

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176 citations

Elsa Du Bruyn, Cari Stek, Remy Daroowala, René Goliath, Fatima Abrahams +9 more

Eosinophils are part of the granulocyte response in tuberculosis and promote host resistance in mice

The Journal of Experimental Medicine(2021)10.1084/jem.20210469

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94 citations

Ehydel Castro, Zhidong Hu, Artur T. L. Queiroz, Claire E. Tocheny, Maike Assmann +27 more

T cell-tropic HIV efficiently infects alveolar macrophages through contact with infected CD4+ T cells

Scientific Reports(2021)10.1038/s41598-021-82066-x

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44 citations

Alice H. Linder, Shillah N. Luhembo, Stephanie Banning, Martin J. Deymier, Thomas Diefenbach +11 more

Plasma Pharmacokinetics of High-Dose Oral versus Intravenous Rifampicin in Patients with Tuberculous Meningitis: a Randomized Controlled Trial

Antimicrobial Agents and Chemotherapy(2021)10.1128/aac.00140-21

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39 citations

Angharad Davis, Cari Stek, Maxwell Chirehwa, Stephani Botha, Remy Daroowala +16 more

Evaluation of Host Serum Protein Biomarkers of Tuberculosis in sub-Saharan Africa

Frontiers in Immunology(2021)10.3389/fimmu.2021.639174

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38 citations

Clive Hoggart, Novel N. Chegou, Martin Kidd, Tolu Oni, René Goliath +11 more

Recent Developments in Tuberculous Meningitis Pathogenesis and Diagnostics

Wellcome Open Research(2021)10.12688/wellcomeopenres.15506.3

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35 citations

Angharad Davis, Kusum Sharma, Robindra Basu Roy, Ahmad Rizal Ganiem, Enock Kagimu +5 more

Aspirin in tuberculous meningitis

EClinicalMedicine(2021)10.1016/j.eclinm.2021.100871

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0DataRank · unranked

7 citations

Robert J. Wilkinson, Angharad Davis

Host Directed Therapies for Tuberculous Meningitis

Wellcome Open Research(2021)10.12688/wellcomeopenres.16474.2

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15 citations

Joseph Donovan, Marise Bremer, Ronald van Toorn, Johan F. Schoeman, Ariba Dadabhoy +8 more

Loss of recognition of SARS-CoV-2 B.1.351 variant spike epitopes but overall preservation of T cell immunity

medRxiv(2021)10.1101/2021.06.03.21258307

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0DataRank · unranked

10 citations

Roanne Keeton, Thandeka Moyo-Gwete, Tandile Hermanus, Prudence Kgagudi, Richard Baguma +21 more

Severity and inpatient mortality of COVID-19 pneumonia from Beta variant infection: a clinical cohort study in Cape Town, South Africa

medRxiv(2021)10.1101/2021.11.04.21265916

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0DataRank · unranked

5 citations

Aimee Lifson, Francesca Little, Timothy J. de Wet, Nectarios Papavarnavas, Gert Marais +14 more

Plasma pharmacokinetics of high dose oral versus intravenous rifampicin in patients with tuberculous meningitis: a randomized controlled trial

medRxiv(2021)10.1101/2021.02.11.21250624

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0DataRank · unranked

2 citations

Angharad Davis, Cari Stek, Maxwell Chirehwa, Stephani Botha, Remy Daroowala +16 more

Eosinophils are an integral component of the pulmonary granulocyte response in Tuberculosis and promote host resistance in mice

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.29.446277

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0DataRank · unranked

2 citations

Ehydel Castro, Zhidong Hu, Artur T. L. Queiroz, Claire E. Tocheny, Maike Assmann +27 more

Escape from recognition of SARS-CoV-2 variant spike epitopes but overall preservation of T cell immunity

Science Translational Medicine(2022)10.1126/scitranslmed.abj6824

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0DataRank · unranked

126 citations

Roanne Keeton, Thandeka Moyo-Gwete, Tandile Hermanus, Prudence Kgagudi, Richard Baguma +23 more

GPX4 regulates cellular necrosis and host resistance in Mycobacterium tuberculosis infection

The Journal of Experimental Medicine(2022)10.1084/jem.20220504

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0DataRank · unranked

90 citations

Taylor W. Foreman, Sivaranjani Namasivayam, Kerry L. Hilligan, Keith D. Kauffman, Caio César Barbosa Bomfim +14 more

Xpert Ultra testing of blood in severe HIV-associated tuberculosis to detect and measure Mycobacterium tuberculosis blood stream infection: a diagnostic and disease biomarker cohort study

The Lancet Microbe(2022)10.1016/s2666-5247(22)00062-3

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30 citations

Charlotte Schutz, Nomfundo Sibiya, Avuyonke Balfour, Amy Ward, Muki Shey +7 more

Convalescent plasma in the treatment of moderate to severe COVID-19 pneumonia: a randomized controlled trial (PROTECT-Patient Trial)

Scientific Reports(2022)10.1038/s41598-022-06221-8

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0DataRank · unranked

33 citations

Tanya Nadia Glatt, Marion Vermeulen, Francesca Little, Ronél Swanevelder, Claire L. Barrett +25 more

Comorbidity of mental ill-health in tuberculosis patients under treatment in a rural province of South Africa: a cross-sectional survey

BMJ Open(2022)10.1136/bmjopen-2021-058013

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23 citations

Robert J. Wilkinson, Zukiswa Zingela, Yanga Thungana

Comparison of the frequency and phenotypic profile of Mycobacterium tuberculosis-specific CD4 T cells between the site of disease and blood in pericardial tuberculosis

Frontiers in Immunology(2022)10.3389/fimmu.2022.1009016

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18 citations

Sheena Ruzive, Patrick Howlett, Maddalena Cerrone, Ashley J. Jacobs, Cecilia S. Lindestam Arlehamn +9 more

Pharmacokinetics of antitubercular drugs in patients hospitalized with HIV-associated tuberculosis: a population modeling analysis

Wellcome Open Research(2022)10.12688/wellcomeopenres.17660.2

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2 citations

Maxwell Chirehwa, Charlotte Schutz, David Barr, Amy Ward, Saskia Janssen +9 more

A comparison of the population pharmacokinetics of rifampicin, isoniazid and pyrazinamide between hospitalized and non-hospitalized tuberculosis patients with or without HIV

Wellcome Open Research(2022)10.12688/wellcomeopenres.17660.1

N/A

0DataRank · unranked

1 citations

Maxwell Chirehwa, Charlotte Schutz, David Barr, Amy Ward, Saskia Janssen +9 more

Epidemiology and outcomes of SARS-CoV-2 infection associated with anti-nucleocapsid seropositivity in Cape Town, South Africa

medRxiv(2022)10.1101/2022.12.01.22282927

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5 citations

Helena Vreede, Mary‐Ann Davies, Alexa Heekes, Emma Kalk, Diana Hardie +20 more

Assessing the clinical severity of the Omicron variant in the Western Cape Province, South Africa, using the diagnostic PCR proxy marker of RdRp target delay to distinguish between Omicron and Delta infections – a survival analysis

medRxiv(2022)10.1101/2022.01.13.22269211

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0DataRank · unranked

3 citations

Mary‐Ann Davies, Alexa Heekes, Carolyn Williamson, Ziyaad Valley‐Omar, Diana Hardie +22 more

A phase 2A trial of the safety and tolerability of increased dose rifampicin and adjunctive linezolid, with or without aspirin, for HIV-associated tuberculous meningitis (The LASER-TBM Trial)

medRxiv(2022)10.1101/2022.07.26.22278065

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3 citations

Sean Wasserman, Cari Stek, Mpumi Maxebengula, Chen Liang, Stephani Stegmann +27 more

Blood and site of disease inflammatory profiles differ in HIV-1-infected pericardial tuberculosis patients

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.21.513232

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0DataRank · unranked

0 citations

Elsa Du Bruyn, Sheena Ruzive, Patrick Howlett, Alan Sher, Katrin D. Mayer-Barber +5 more

Recent advances in the treatment of tuberculosis

Clinical Microbiology and Infection(2023)10.1016/j.cmi.2023.07.013

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0DataRank · unranked

117 citations

Martin J. Boeree, Dumitru Chesov, Keertan Dheda, Gunar Günther, C. Robert Horsburgh +13 more

Linezolid Population Pharmacokinetic Model in Plasma and Cerebrospinal Fluid Among Patients With Tuberculosis Meningitis

The Journal of Infectious Diseases(2023)10.1093/infdis/jiad413

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18 citations

Sean Wasserman, Mahmoud Tareq Abdelwahab, Angharad Davis, Cari Stek, Lubbe Wiesner +5 more

Identification and control for the effects of bioinformatic globin depletion on human RNA-seq differential expression analysis

Scientific Reports(2023)10.1038/s41598-023-28218-7

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0DataRank · unranked

16 citations

Francisco Lakay, Hanif Esmail, Craig Kinnear, Bianca Sansom, Brigitte Glanzmann +4 more

IL-27 inhibits anti- Mycobacterium tuberculosis innate immune activity of primary human macrophages

Tuberculosis(2023)10.1016/j.tube.2023.102326

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0DataRank · unranked

9 citations

James Barber, Robert J. Wilkinson, Sandra M. Newton, Ankita Garg, Hailey Gollnick

A preclinical model of TB meningitis to determine drug penetration and activity at the sites of disease

Antimicrobial Agents and Chemotherapy(2023)10.1128/aac.00671-23

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0DataRank · unranked

5 citations

Rosleine Antilus Sainte, Mark Hansen, Paul Parigi, Firat Kaya, Katherine LoMauro +7 more

Derivation of a high-resolution CT-based, semi-automated radiographic score in tuberculosis and its relationship to bacillary load and antitubercular therapy

European Respiratory Journal(2023)10.1183/13993003.00600-2023

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0DataRank · unranked

1 citations

Elsa Du Bruyn, Grace Hyun J. Kim, Irene Da Costa, Jihey Lee, Alan Sher +4 more

Blood and Site of Disease Inflammatory Profiles Differ in Patients With Pericardial Tuberculosis and Human Immunodeficiency Virus Type 1

Open Forum Infectious Diseases(2023)10.1093/ofid/ofad128

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0DataRank · unranked

2 citations

Elsa Du Bruyn, Sheena Ruzive, Patrick Howlett, Maddalena Cerrone, Alan Sher +6 more

Linezolid population pharmacokinetic model in plasma and cerebrospinal fluid among patients with tuberculosis meningitis

medRxiv(2023)10.1101/2023.04.06.23288230

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0DataRank · unranked

1 citations

Sean Wasserman, Mahmoud Tareq Abdelwahab, Angharad Davis, Cari Stek, Lubbe Wiesner +5 more

A Nanopore sequencing-based pharmacogenomic panel to personalize tuberculosis drug dosing

medRxiv(2023)10.1101/2023.09.08.23295248

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0DataRank · unranked

0 citations

Késia Esther da Silva, Neesha Rockwood, Roeland E. Wasmann, Nombuso Yende, Taeksun Song +5 more

Changing character and waning impact of COVID-19 at a tertiary centre in Cape Town, South Africa

Southern African Journal of Infectious Diseases(2023)10.4102/sajid.v38i1.550

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0DataRank · unranked

0 citations

Petro Booysen, Linda Boloko, Marguerite Adriaanse, Timothy J. de Wet, Aimee Lifson +15 more

Classification of early tuberculosis states to guide research for improved care and prevention: an international Delphi consensus exercise

The Lancet Respiratory Medicine(2024)10.1016/s2213-2600(24)00028-6

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0DataRank · unranked

164 citations

Syed Mohammad Asad Zaidi, Brian W Allwood, Puneet Dewan, Glenda Gray, Mikashmi Kohli +51 more

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