Michael Karin

Also affiliated with University of California San Diego

Biochemistry, Genetics and Molecular BiologyImmunology and MicrobiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 59 papers. Top paper: “A guideline on the molecular ecosystem regulating ferroptosis”.

A guideline on the molecular ecosystem regulating ferroptosis

Nature Cell Biology(2024)10.1038/s41556-024-01360-8

N/A

4.1DataRank · unranked

257 citations

Xin Chen, Andreas Linkermann, Xuejun Jiang, Rui Kang, Valerian E. Kagan +43 more

mAChR4 suppresses liver disease via GAP-induced antimicrobial immunity

Nature(2025)10.1038/s41586-025-09395-z

N/A

0.523DataRank · unranked

17 citations

Fernanda Raya Tonetti, Ryan Bruellman, Rocío Brea, Núria Pell, Phillipp Hartmann +22 more

Fructose stimulated de novo lipogenesis is promoted by inflammation

Nature Metabolism(2020)10.1038/s42255-020-0261-2

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0DataRank · unranked

320 citations

Giuseppe Di, Saskia Reibe, Darren C. Henstridge, Courtney R. Green, Alison Vrbanac +21 more

NRF2 as a regulator of cell metabolism and inflammation in cancer

Carcinogenesis(2020)10.1093/carcin/bgaa039

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0DataRank · unranked

317 citations

Laura Antonucci, Michael Karin, Feng He

Immunotherapy, Inflammation and Colorectal Cancer

Cells(2020)10.3390/cells9030618

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0DataRank · unranked

302 citations

Rachael Katie Ngu, Shabnam Shalapour, Michael Karin, Charles Robert Lichtenstern

Sestrins are evolutionarily conserved mediators of exercise benefits

Nature Communications(2020)10.1038/s41467-019-13442-5

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0DataRank · unranked

115 citations

Alyson Sujkowski, Sim Namkoong, Bondong Gu, Tyler Cobb, Bo Young Kim +10 more

NRF2 activates growth factor genes and downstream AKT signaling to induce mouse and human hepatomegaly

Journal of Hepatology(2020)10.1016/j.jhep.2020.01.023

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0DataRank · unranked

107 citations

Laura Antonucci, Shinichiro Yamachika, Zechuan Zhang, Koji Taniguchi, Atsushi Umemura +9 more

NF-κB-p62-NRF2 survival signaling is associated with high ROR1 expression in chronic lymphocytic leukemia

Cell Death and Differentiation(2020)10.1038/s41418-020-0496-1

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0DataRank · unranked

51 citations

Emanuela M. Ghia, Laura Antonucci, Natasha Sharma, Laura Z. Rassenti, Jinyi Xu +4 more

Interplay of IKK/NF-κB signaling in macrophages and myofibers promotes muscle degeneration in Duchenne muscular dystrophy

UNC Libraries(2020)10.17615/9t1d-hf29

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0DataRank · unranked

0 citations

Michael Karin, Zarife Sahenk, Micheal Carathers, Michael I. Weinstein, Tepmanas Bupha‐Intr +12 more

Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation

Immunity(2021)10.1016/j.immuni.2021.05.004

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0DataRank · unranked

408 citations

Yuan Liu, A. Nilsson, Raphaella Gatchalian, Timothy R. Crother, Warren G. Tourtellotte +15 more

Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis

Cancer Cell(2021)10.1016/j.ccell.2021.02.016

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0DataRank · unranked

221 citations

Fei Yang, Rao Fu, Xin Li, Randall P. French, Evangeline Mose +15 more

“Sweet death”: Fructose as a metabolic toxin that targets the gut-liver axis

Cell Metabolism(2021)10.1016/j.cmet.2021.09.004

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0DataRank · unranked

177 citations

Michael Karin, Mark A. Febbraio

Soluble α-synuclein–antibody complexes activate the NLRP3 inflammasome in hiPSC-derived microglia

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2025847118

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0DataRank · unranked

135 citations

Kristopher L. Nazor, Yvonne S. Eisele, Titas Grabauskas, Nima Dolatabadi, James Parker +12 more

Activation of NF-κB and p300/CBP potentiates cancer chemoimmunotherapy through induction of MHC-I antigen presentation

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2025840118

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0DataRank · unranked

99 citations

Ingmar N. Bastian, Mark D. Long, Michelle T. Dow, Weihua Li, Tao Liu +28 more

Autophagy-mitophagy induction attenuates cardiovascular inflammation in a murine model of Kawasaki disease vasculitis

JCI Insight(2021)10.1172/jci.insight.151981

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0DataRank · unranked

92 citations

Asli Beyza Ozdemir, Debbie Moreira, Angela C. Gomez, Malcolm Lane, Rebecca A. Porritt +15 more

CRIg on liver macrophages clears pathobionts and protects against alcoholic liver disease

Nature Communications(2021)10.1038/s41467-021-27385-3

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0DataRank · unranked

75 citations

Huikuan Chu, Katharina Brandl, Lu Jiang, Su-Ling Zeng, Nairika Meshgin +18 more

Regulation of antitumor immunity by inflammation-induced epigenetic alterations

Cellular and Molecular Immunology(2021)10.1038/s41423-021-00756-y

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0DataRank · unranked

61 citations

Shabnam Shalapour, Michael Karin

Seroprevalence of antibodies to SARS-CoV-2 in healthcare workers: a cross-sectional study

BMJ Open(2021)10.1136/bmjopen-2020-043584

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0DataRank · unranked

49 citations

Gregory J. Botwin, Christine M. Albert, Mona Alotaibi, Moshe Arditi, Anders H. Berg +34 more

The neglected brothers come of age: B cells and cancer

Seminars in Immunology(2021)10.1016/j.smim.2021.101479

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0DataRank · unranked

49 citations

Michael Karin, Shabnam Shalapour

From Liver Fat to Cancer: Perils of the Western Diet

Cancers(2021)10.3390/cancers13051095

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0DataRank · unranked

35 citations

Feng He, Michael Karin, Ju Youn Kim

Nondegradable Collagen Increases Liver Fibrosis but Not Hepatocellular Carcinoma in Mice

American Journal Of Pathology(2021)10.1016/j.ajpath.2021.05.019

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0DataRank · unranked

25 citations

Cuili Zhang, Shuang Liang, Xiao Liu, Takahiro Nishio, Sara Brin Rosenthal +9 more

Concurrent Disruption of the Ras/MAPK and NF-κB Pathways Induces Circadian Deregulation and Hepatocarcinogenesis

Molecular Cancer Research(2021)10.1158/1541-7786.mcr-21-0479

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0DataRank · unranked

12 citations

Yan Liang, Gaowei Wang, Xiaoxue Lin, Meixiang Yang, Michael Karin +3 more

IL6ST–induced muscarinic receptor opens goblet cell associated antigen passages to suppress alcoholic liver disease

Research Square(2021)10.21203/rs.3.rs-366644/v1

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0DataRank · unranked

4 citations

Cristina Llorente, Ryan Bruellman, Noemí Cabré, Rocío Brea, Núria Pell +13 more

Genuine Selective Caspase-2 Inhibition with new Irreversible Small Peptidomimetics

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.13.472505

N/A

0DataRank · unranked

0 citations

Julie Anastasie, Feryel Soualmia, Pascale Coric, Ju Youn Kim, Gullen Lacin +9 more

Tumor necrosis factor alpha stimulates AP-1 activity through prolonged activation of the c-Jun kinase.

UNC Libraries(2021)10.17615/afbz-da02

N/A

0DataRank · unranked

0 citations

Audrey Minden, Michael Karin, John Westwick, C Weitzel, David A. Brenner

Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis

Nature(2022)10.1038/s41586-022-05289-6

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0DataRank · unranked

336 citations

Yoshinobu Saito, Ajay Nair, Dianne H. Dapito, Le‐Xing Yu, Aashreya Ravichandra +33 more

Aberrant iron distribution via hepatocyte-stellate cell axis drives liver lipogenesis and fibrosis

Cell Metabolism(2022)10.1016/j.cmet.2022.07.006

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0DataRank · unranked

213 citations

Zhongmou Jin, Gautam Bandyopadhyay, Gaowei Wang, Dinghong Zhang, Karina Cunha e Rocha +7 more

NF-κB: A Double-Edged Sword Controlling Inflammation

Biomedicines(2022)10.3390/biomedicines10061250

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0DataRank · unranked

136 citations

Zhenyu Zhong, Michael Karin, Danhui Liu

PIDDosome-SCAP crosstalk controls high-fructose-diet-dependent transition from simple steatosis to steatohepatitis

Cell Metabolism(2022)10.1016/j.cmet.2022.08.005

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0DataRank · unranked

37 citations

Lily Q. Wang, Valentina C. Sladky, Tae Gyu Oh, Junlai Liu, Kaitlyn Trinh +8 more

Lactational delivery of Triclosan promotes non-alcoholic fatty liver disease in newborn mice

Nature Communications(2022)10.1038/s41467-022-31947-4

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0DataRank · unranked

29 citations

Xiaojing Yang, Elvira Mennillo, Jeffrey Ding, Jeramie D. Watrous, Mohit Jain +4 more

Genuine selective caspase-2 inhibition with new irreversible small peptidomimetics

Cell Death and Disease(2022)10.1038/s41419-022-05396-2

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0DataRank · unranked

18 citations

Julie Anastasie, Feryel Soualmia, Pascale Coric, Ju Youn Kim, Lily Q. Wang +15 more

IKKα-deficient lung adenocarcinomas generate an immunosuppressive microenvironment by overproducing Treg-inducing cytokines

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2120956119

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0DataRank · unranked

19 citations

Xin Li, Buyong Ma, Jami Willette‐Brown, Feng Zhu, Chengfei Jiang +11 more

Diabesity? No worries, FKBP11 to the rescue

Cell Metabolism(2022)10.1016/j.cmet.2022.06.006

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0DataRank · unranked

2 citations

Michael Karin

Collagen remodeling dictates pancreatic cancer bioenergetics and outcome through DDR1 activation or degradation

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.04.02.486837

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0DataRank · unranked

0 citations

Fei Yang, Rao Fu, Brittney Trinh, Nina Sun, Junlai Liu +16 more

ATF4 suppresses hepatocarcinogenesis by inducing SLC7A11 (xCT) to block stress-related ferroptosis

Journal of Hepatology(2023)10.1016/j.jhep.2023.03.016

N/A

0DataRank · unranked

375 citations

Peng Zhang, Junlai Liu, Ruolei Wang, Randal J. Kaufman, Benjamin C. Yaden +2 more

Collagen architecture and signaling orchestrate cancer development

Trends in cancer(2023)10.1016/j.trecan.2023.06.002

N/A

0DataRank · unranked

87 citations

Michael Karin, Hua Su

Oxidized mitochondrial DNA: a protective signal gone awry

Trends in Immunology(2023)10.1016/j.it.2023.01.006

N/A

0DataRank · unranked

80 citations

Michael Karin, Hongxu Xian

Multifaceted collagen-DDR1 signaling in cancer

Trends in Cell Biology(2023)10.1016/j.tcb.2023.08.003

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0DataRank · unranked

47 citations

Michael Karin, Hua Su

Angiotensin II receptor inhibition ameliorates liver fibrosis and enhances hepatocellular carcinoma infiltration by effector T cells

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2300706120

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0DataRank · unranked

46 citations

Yahui Zhu, Maiya Lee, Albert Nguyen, Nicolas T. Ryujin, Jian Yu Huang +8 more

Fructose-1,6-bisphosphatase is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness

Cell Metabolism(2023)10.1016/j.cmet.2023.03.021

N/A

0DataRank · unranked

38 citations

Yahui Zhu, Kosuke Watari, Maiya Lee, Junlai Liu, Sofia Perez +18 more

Angiotensin II receptor inhibition ameliorates liver fibrosis and enhances hepatocellular carcinoma infiltration by effector T cells

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.05.531188

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0DataRank · unranked

5 citations

Yahui Zhu, Maiya Lee, Albert Nguyen, Nicolas T. Ryujin, Jian Yu Huang +7 more

IRF1 regulates self-renewal and stress-responsiveness to support hematopoietic stem cell maintenance

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.24.525321

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0DataRank · unranked

4 citations

Hongxu Xian, Shabnam Shalapour, Jörg Cammenga, Michael Karin, A. Nilsson

FBP1 is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.05.531181

N/A

0DataRank · unranked

0 citations

Yahui Zhu, Kosuke Watari, Maiya Lee, Junlai Liu, Sofia Perez +18 more

Data from c-Jun NH2-Terminal Kinase 1 Is a Critical Regulator for the Development of Gastric Cancer in Mice

(2023)10.1158/0008-5472.c.6497559

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0DataRank · unranked

0 citations

Shin Maeda, Yohko Hikiba, Ayako Yanai, Kei Sakamoto, Hayato Nakagawa +4 more

Data from Macrophage Expression of Hypoxia-Inducible Factor-1α Suppresses T-Cell Function and Promotes Tumor Progression

(2023)10.1158/0008-5472.c.6500715

N/A

0DataRank · unranked

0 citations

Christian Stockmann, Mark P. Rubinstein, Debbie Liao, Na Zhang, David G. DeNardo +5 more

IL-22 resolves MASLD via enterocyte STAT3 restoration of diet-perturbed intestinal homeostasis

Cell Metabolism(2024)10.1016/j.cmet.2024.08.012

N/A

0DataRank · unranked

48 citations

Junlai Liu, Allen Lee, Irene Tsaur, Masafumi Ohira, Vivian Duong +20 more

MASH as an emerging cause of hepatocellular carcinoma: current knowledge and future perspectives

Molecular Oncology(2024)10.1002/1878-0261.13685

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0DataRank · unranked

35 citations

Ju Youn Kim, Michael Karin

The Past and Future of Inflammation as a Target to Cancer Prevention

Cancer Prevention Research(2024)10.1158/1940-6207.capr-23-0423

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0DataRank · unranked

21 citations

Michael Karin, Laura Antonucci

Triclosan administration to humanized UDP-glucuronosyltransferase 1 neonatal mice induces UGT1A1 through a dependence on PPARα and ATF4

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.107340

N/A

0DataRank · unranked

4 citations

Xiaojing Yang, Elvira Mennillo, Samantha Wong, Sabrina Le, Jia Ying Ashley Teo +8 more

FBP1 controls liver cancer evolution from senescent MASH hepatocytes

Nature(2025)10.1038/s41586-024-08317-9

N/A

0DataRank · unranked

47 citations

Yahui Zhu, Shuvro P. Nandi, Maiya Lee, Kosuke Watari, Breanna Bareng +25 more

Mitochondrial DNA oxidation propagates autoimmunity by enabling plasmacytoid dendritic cells to induce TFH differentiation

Nature Immunology(2025)10.1038/s41590-025-02179-7

N/A

0DataRank · unranked

16 citations

Kosuke Watari, Masafumi Ohira, Jonathan S. Brito, Peng He, Janset Onyuru +4 more

Innate immune cells link dietary cues to normal and abnormal metabolic regulation

Nature Immunology(2025)10.1038/s41590-024-02037-y

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0DataRank · unranked

14 citations

Kosuke Watari, Michael Karin, Peng Zhang

Endoplasmic reticulum stress at the forefront of fatty liver diseases and cancer

Pharmacological Reviews(2025)10.1016/j.pharmr.2025.100096

N/A

0DataRank · unranked

10 citations

Ju Youn Kim, Michael Karin

Self-amplifying NRF2–EZH2 epigenetic loop converts KRAS-initiated progenitors to invasive pancreatic cancer

Nature Cancer(2025)10.1038/s43018-025-01003-3

N/A

0DataRank · unranked

9 citations

Na Li, Ángeles Durán, Isidoro Cobo, Chiara Nicoletti, Kosuke Watari +37 more

The FBP1‐TP53‐NRF2 metabolic switch in metabolic dysfunction‐associated steatohepatitis‐hepatocellular carcinoma progression and senescence reversal

Clinical and Translational Medicine(2025)10.1002/ctm2.70293

N/A

0DataRank · unranked

4 citations

Donglin Wei, Michael Karin, Li Gu, Yahui Zhu

Obesity rewires CD8+ T cell iron metabolism in adipose tissue to fuel metabolic inflammation

Metabolism(2025)10.1016/j.metabol.2025.156438

N/A

0DataRank · unranked

1 citations

Zixuan Zeng, Lishuan Wang, Wei Yuan, Karina Cunha e Rocha, Jun-Ho Park +12 more

PKCλ/ι Loss Induces Autophagy, Oxidative Phosphorylation, and NRF2 to Promote Liver Cancer Progression

Cancer Cell(2020)10.1016/j.ccell.2020.05.018

N/A

0DataRank · unranked

154 citations

Masayuki Sugimoto, Esperanza Arias, Hiroaki Kasashima, Thekla Cordes, Juan F. Linares +14 more

Author Correction: FBP1 controls liver cancer evolution from senescent MASH hepatocytes

Nature(2025)10.1038/s41586-025-08653-4

N/A

0DataRank · unranked

1 citations

Yahui Zhu, Shuvro P. Nandi, Maiya Lee, Kosuke Watari, Breanna Bareng +26 more

Sestrin prevents atrophy of disused and aging muscles by integrating anabolic and catabolic signals

Nature Communications(2020)10.1038/s41467-019-13832-9

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0DataRank · unranked

153 citations

Eusebio Perdiguero, Antonio L. Serrano, Pedro Sousa‐Victor, Laura Ortet, Mercè Jardı́ +8 more