Natarajan Kannan

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 5%percentile

0.538Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Dark kinase annotation, mining, and visualization using the Protein Kinase Ontology

PeerJ(2023)10.7717/peerj.16087

Top 36%

0.538DataRank

Top 36%12 citations

Nathan Gravel, Liang‐Chin Huang, Wayland Yeung, Elika Bozorgi, N. George Bendzunas +3 more

Papers

Driven by 67 papers — median percentile 64. Top paper: “Deep evolutionary analysis reveals the design principles of fold A glycosyltransferases”.

Deep evolutionary analysis reveals the design principles of fold A glycosyltransferases

eLife(2020)10.7554/elife.54532

N/A

2.4DataRank · unranked

99 citations

Aarya Venkat, Liang‐Chin Huang, Zhongliang Zhou, Wayland Yeung, Khaled Rasheed +5 more

Dark kinase annotation, mining, and visualization using the Protein Kinase Ontology

PeerJ(2023)10.7717/peerj.16087

Top 36%

0.538DataRank

Top 36%12 citations

Nathan Gravel, Liang‐Chin Huang, Wayland Yeung, Elika Bozorgi, N. George Bendzunas +3 more

Mechanistic and evolutionary insights into isoform-specific ‘supercharging’ in DCLK family kinases

eLife(2023)10.7554/elife.87958

N/A

0.450DataRank · unranked

13 citations

Grace Watterson, Dominic P. Byrne, Brady O’Boyle, Safal Shrestha, Nathan Gravel +10 more

Extensive non-canonical phosphorylation in human cells revealed using strong-anion exchange-mediated phosphoproteomics

10.1101/202820

N/A

0.416DataRank · unranked

15 citations

Simon Perkins, Zheng Ruan, Natarajan Kannan, Philip Brownridge, Dominic P Byrne +4 more

Redox regulation and dynamic control of brain-selective kinases BRSK1/2 in the AMPK family through cysteine-based mechanisms

eLife(2024)10.7554/elife.92536

N/A

0.165DataRank · unranked

2 citations

Dominic P. Byrne, Safal Shrestha, Leonard A. Daly, Sally O. Oswald, Samiksha Katiyar +6 more

GTXplorer: A portal to navigate and visualize the evolutionary information encoded in fold A glycosyltransferases

Glycobiology(2021)10.1093/glycob/cwab082

N/A

0.104DataRank · unranked

1 citations

Saber Soleymani, Amitabh Priyadarshi, Aarya Venkat, Wayland Yeung, Krzysztof Kochut +2 more

Nucleotide Binding, Evolutionary Insights, and Interaction Partners of the Pseudokinase Unc-51-like Kinase 4

Structure(2020)10.1016/j.str.2020.07.016

N/A

0DataRank · unranked

39 citations

Deep Chatterjee, Sebastian Mathea, Safal Shrestha, Jonathan St‐Germain, Manipa Saha +5 more

A Chemical Probe for Dark Kinase STK17B Derives Its Potency and High Selectivity through a Unique P-Loop Conformation

Journal of Medicinal Chemistry(2020)10.1021/acs.jmedchem.0c01174

N/A

0DataRank · unranked

30 citations

A. Chaikuad, Carrow I. Wells, Safal Shrestha, William J. Zuercher, Julie E. Pickett +10 more

A redox-active switch in fructosamine-3-kinases expands the regulatory repertoire of the protein kinase superfamily

Science Signaling(2020)10.1126/scisignal.aax6313

N/A

0DataRank · unranked

24 citations

Samiksha Katiyar, Carlos E. Sanz-Rodríguez, Nolan R. Kemppinen, Hyun W. Kim, Renuka Kadirvelraj +12 more

A resource for exploring the understudied human kinome for research and therapeutic opportunities

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.02.022277

N/A

0DataRank · unranked

26 citations

Changchang Liu, Benjamin M. Gyori, John A. Bachman, Albert Steppi, Clemens Hug +7 more

Nucleotide binding, evolutionary insights and interaction partners of the pseudokinase Unc-51-like kinase 4

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.18.159293

N/A

0DataRank · unranked

2 citations

Deep Chatterjee, Sebastian Mathea, Safal Shrestha, Jonathan St‐Germain, Manipa Saha +5 more

A Chemical Probe for Dark Kinase STK17B Derives its Potency and High Selectivity Through a Unique P-loop Conformation

ChemRxiv(2020)10.26434/chemrxiv.12616178

N/A

0DataRank · unranked

2 citations

A. Chaikuad, Carrow I. Wells, Safal Shrestha, William J. Zuercher, Julie E. Pickett +10 more

A Chemical Probe for Dark Kinase STK17B Derives its Potency and High Selectivity Through a Unique P-loop Conformation

ChemRxiv(2020)10.26434/chemrxiv.12616178.v1

N/A

0DataRank · unranked

1 citations

A. Chaikuad, Carrow I. Wells, Safal Shrestha, William J. Zuercher, Julie E. Pickett +10 more

mTORC2 controls the activity of PKC and Akt by phosphorylating a conserved TOR interaction motif

Science Signaling(2021)10.1126/scisignal.abe4509

N/A

0DataRank · unranked

113 citations

Gema Lordén, Jacob M. Wozniak, Andreas Feichtner, Wayland Yeung, Alexandr P. Kornev +13 more

Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis

Nature Communications(2021)10.1038/s41467-021-22400-z

N/A

0DataRank · unranked

107 citations

Yanxiang Meng, Akiko Koide, Jarrod J. Sandow, Eric Denbaum, Annette V. Jacobsen +14 more

Mapping the glycosyltransferase fold landscape using interpretable deep learning

Nature Communications(2021)10.1038/s41467-021-25975-9

N/A

0DataRank · unranked

54 citations

Zhongliang Zhou, Wayland Yeung, Kelley W. Moremen, Sheng Li, Natarajan Kannan +1 more

KinOrtho: a method for mapping human kinase orthologs across the tree of life and illuminating understudied kinases

BMC Bioinformatics(2021)10.1186/s12859-021-04358-3

N/A

0DataRank · unranked

32 citations

Rahil Taujale, Nathan Gravel, Aarya Venkat, Wayland Yeung, Dominic P. Byrne +3 more

Evolution of Functional Diversity in the Holozoan Tyrosine Kinome

Molecular Biology and Evolution(2021)10.1093/molbev/msab272

N/A

0DataRank · unranked

29 citations

Annie Kwon, Rahil Taujale, Claire Bunn, Aarya Venkat, Natarajan Kannan +1 more

Peters plus syndrome mutations affect the function and stability of human β1,3-glucosyltransferase

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.100843

N/A

0DataRank · unranked

12 citations

Aarya Venkat, Rahil Taujale, James L. Mull, Atsuko Ito, Natarajan Kannan +2 more

Granulovirus PK-1 kinase activity relies on a side-to-side dimerization mode centered on the regulatory αC helix

Nature Communications(2021)10.1038/s41467-021-21191-7

N/A

0DataRank · unranked

7 citations

Christopher R. Horne, Safal Shrestha, J.R. Keown, Lung‐Yu Liang, Samuel N. Young +8 more

KinOrtho: a method for mapping human kinase orthologs across the tree of life and illuminating understudied kinases

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.05.434161

N/A

0DataRank · unranked

2 citations

Rahil Taujale, Nathan Gravel, Aarya Venkat, Wayland Yeung, Dominic P. Byrne +3 more

Evolution of functional diversity in the holozoan tyrosine kinome

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.03.454916

N/A

0DataRank · unranked

1 citations

Annie Kwon, Rahil Taujale, Claire Bunn, Aarya Venkat, Natarajan Kannan +1 more

Protein Kinase Cγ Mutations Drive Spinocerebellar Ataxia Type 14 by Impairing Autoinhibition

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.24.449810

N/A

0DataRank · unranked

0 citations

Timothy R. Baffi, Alexandr P. Kornev, Maya T. Kunkel, Mario Malfavon, Donghui Chen +9 more

Mapping the glycosyltransferase fold landscape using deep learning

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.05.451183

N/A

0DataRank · unranked

0 citations

Zhongliang Zhou, Wayland Yeung, Kelley W. Moremen, Sheng Li, Natarajan Kannan +1 more

Functional classification and validation of yeast prenylation motifs using machine learning and genetic reporters

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.30.470454

N/A

0DataRank · unranked

0 citations

Wayland Yeung, Arnav Goyal, Zhongliang Zhou, Emily R. Hildebrandt, Natarajan Kannan +2 more

Polymerization of the backbone of the pectic polysaccharide rhamnogalacturonan I

Nature Plants(2022)10.1038/s41477-022-01270-3

N/A

0DataRank · unranked

51 citations

Melani A. Atmodjo, Chin Huang, Zhongwei Gao, Aarya Venkat, Rahil Taujale +4 more

Functional classification and validation of yeast prenylation motifs using machine learning and genetic reporters

PLoS ONE(2022)10.1371/journal.pone.0270128

N/A

0DataRank · unranked

12 citations

Wayland Yeung, Arnav Goyal, Zhongliang Zhou, Emily R. Hildebrandt, Natarajan Kannan +2 more

Protein kinase inhibitor selectivity “hinges” on evolution

Structure(2022)10.1016/j.str.2022.11.004

N/A

0DataRank · unranked

7 citations

George Bendzunas, Natarajan Kannan, Safal Shrestha

Computational tools and resources for pseudokinase research

Methods in enzymology on CD-ROM/Methods in enzymology(2022)10.1016/bs.mie.2022.03.040

N/A

0DataRank · unranked

10 citations

Safal Shrestha, Krzysztof Kochut, Patrick A. Eyers, Natarajan Kannan, Brady O’Boyle

Modularity of the hydrophobic core and evolution of functional diversity in fold A glycosyltransferases

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102212

N/A

0DataRank · unranked

8 citations

Daniel Tehrani, Rahil Taujale, Wayland Yeung, Nathan Gravel, Kelley W. Moremen +2 more

Evolutionary and cellular analysis of the ‘dark’ pseudokinase PSKH2

Biochemical Journal(2022)10.1042/bcj20220474

N/A

0DataRank · unranked

5 citations

Safal Shrestha, Leonard A. Daly, Vanessa Marensi, Krithika Ramakrishnan, Claire E. Eyers +3 more

Defining pseudoenzymes in glycosylation pathways

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.0i208

N/A

0DataRank · unranked

0 citations

Natarajan Kannan

Polymerization of the backbone of the pectic polysaccharide rhamnogalacturonan I

Research Square(2022)10.21203/rs.3.rs-1475173/v1

N/A

0DataRank · unranked

0 citations

Melani A. Atmodjo, Chin Pao Huang, Zhongwei Gao, Aarya Venkat, Rahil Taujale +4 more

Evolutionary and cellular analysis of the dark pseudokinase PSKH2

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.10.507278

N/A

0DataRank · unranked

0 citations

Safal Shrestha, Leonard A. Daly, Vanessa Marensi, Krithika Ramakrishnan, Claire E. Eyers +3 more

Phosphorylation-dependent pseudokinase domain dimerization drives full-length MLKL oligomerization

Nature Communications(2023)10.1038/s41467-023-42255-w

N/A

0DataRank · unranked

36 citations

Sarah E. Garnish, Katherine A. Davies, Katrina A. Black, Andrew Leis, Christopher R. Horne +14 more

Phosformer: an explainable transformer model for protein kinase-specific phosphorylation predictions

Bioinformatics(2023)10.1093/bioinformatics/btad046

N/A

0DataRank · unranked

34 citations

Wayland Yeung, Nathan Gravel, Mariah Salcedo, Saber Soleymani, Sheng Li +2 more

Alignment-free estimation of sequence conservation for identifying functional sites using protein sequence embeddings

Briefings in Bioinformatics(2023)10.1093/bib/bbac599

N/A

0DataRank · unranked

33 citations

Zhongliang Zhou, Sheng Li, Natarajan Kannan, Wayland Yeung

Tree visualizations of protein sequence embedding space enable improved functional clustering of diverse protein superfamilies

Briefings in Bioinformatics(2023)10.1093/bib/bbac619

N/A

0DataRank · unranked

27 citations

Zhongliang Zhou, Liju Mathew, Nathan Gravel, Rahil Taujale, Brady O’Boyle +6 more

Structural and biochemical insight into a modular β-1,4-galactan synthase in plants

Nature Plants(2023)10.1038/s41477-023-01358-4

N/A

0DataRank · unranked

13 citations

J.H. Pereira, Rahil Taujale, Wanchen Shao, Vivek S. Bharadwaj, Digantkumar Chapla +9 more

A comprehensive in vivo screen of yeast farnesyltransferase activity reveals broad reactivity across a majority of CXXX sequences

G3 Genes Genomes Genetics(2023)10.1093/g3journal/jkad094

N/A

0DataRank · unranked

13 citations

Emily R. Hildebrandt, Anushka Sarkar, Wayland Yeung, La Ryel A Waldon, Natarajan Kannan +2 more

Predicting protein and pathway associations for understudied dark kinases using pattern-constrained knowledge graph embedding

PeerJ(2023)10.7717/peerj.15815

N/A

0DataRank · unranked

3 citations

Nathan Gravel, Abbas Keshavarzi, Liang‐Chin Huang, Krzysztof Kochut, Natarajan Kannan +1 more

Mechanistic and evolutionary insights into isoform-specific ‘supercharging’ in DCLK family kinases

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.29.534689

N/A

0DataRank · unranked

6 citations

Grace Watterson, Dominic P. Byrne, Brady O’Boyle, Safal Shrestha, Nathan Gravel +10 more

Author Correction: Polymerization of the backbone of the pectic polysaccharide rhamnogalacturonan I

Nature Plants(2023)10.1038/s41477-023-01395-z

N/A

0DataRank · unranked

2 citations

Melani A. Atmodjo, Chin Huang, Zhongwei Gao, Aarya Venkat, Rahil Taujale +4 more

Mechanistic and evolutionary insights into isoform-specific ‘supercharging’ in DCLK family kinases

(2023)10.7554/elife.87958.2

N/A

0DataRank · unranked

2 citations

Grace Watterson, Dominic P. Byrne, Brady O’Boyle, Safal Shrestha, Nathan Gravel +10 more

Redox Regulation of Brain Selective Kinases BRSK1/2: Implications for Dynamic Control of the Eukaryotic AMPK family through Cys-based mechanisms

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.05.561145

N/A

0DataRank · unranked

2 citations

Dominic P. Byrne, Safal Shrestha, Leonard A. Daly, Sally O. Oswald, Samiksha Katiyar +6 more

Mechanistic and evolutionary insights into isoform-specific ‘supercharging’ in DCLK family kinases

(2023)10.7554/elife.87958.1

N/A

0DataRank · unranked

1 citations

Grace Watterson, Dominic P. Byrne, Brady O’Boyle, Safal Shrestha, Nathan Gravel +10 more

Using explainable machine learning to uncover the kinase–substrate interaction landscape

Bioinformatics(2024)10.1093/bioinformatics/btae033

N/A

0DataRank · unranked

15 citations

Wayland Yeung, Saber Soleymani, Nathan Gravel, Mariah Salcedo, Sheng Li +2 more

Discovery of a Cushing’s syndrome protein kinase A mutant that biases signaling through type I AKAPs

Science Advances(2024)10.1126/sciadv.adl1258

N/A

0DataRank · unranked

11 citations

Dominic P. Byrne, Safal Shrestha, Tyler M. Lakey, Kyung‐Soon Lee, Sophia M. Lauer +9 more

Cancer-associated mutations in protein kinase C theta are loss-of-function

Biochemical Journal(2024)10.1042/bcj20240148

N/A

0DataRank · unranked

10 citations

Nathan Gravel, Natarajan Kannan, Alexandra C. Newton, Stefanie Hodapp

Multi-omics reveals new links between Fructosamine-3-Kinase (FN3K) and core metabolic pathways

npj Systems Biology and Applications(2024)10.1038/s41540-024-00390-0

N/A

0DataRank · unranked

6 citations

Rahil Taujale, Samiksha Katiyar, Natarajan Kannan, Safal Shrestha

Informatic challenges and advances in illuminating the druggable proteome

Drug Discovery Today(2024)10.1016/j.drudis.2024.103894

N/A

0DataRank · unranked

5 citations

Nathan Gravel, Zhongliang Zhou, Wayland Yeung, Krystof Kochut, Natarajan Kannan +1 more

Illuminating the functions of the understudied Fructosamine-3-kinase (FN3K) using a multi-omics approach reveals new links to lipid, carbon, and co-factor metabolic pathways

Research Square(2024)10.21203/rs.3.rs-3934957/v1

N/A

0DataRank · unranked

3 citations

Safal Shrestha, Rahil Taujale, Samiksha Katiyar, Natarajan Kannan

Redox Regulation of Brain Selective Kinases BRSK1/2: Implications for Dynamic Control of the Eukaryotic AMPK family through Cys-based mechanisms

eLife(2024)10.7554/elife.92536.1

N/A

0DataRank · unranked

1 citations

Dominic P. Byrne, Safal Shrestha, Leonard A. Daly, Sally O. Oswald, Samiksha Katiyar +6 more

Aurora A regulation by reversible cysteine oxidation reveals evolutionarily conserved redox control of Ser/Thr protein kinase activity

Science Signaling(2020)10.1126/scisignal.aax2713

N/A

0DataRank · unranked

113 citations

Safal Shrestha, Martin Galler, Min Cao, Leonard A. Daly, A. Campbell +5 more

Modeling glycans with AlphaFold 3: capabilities, caveats, and limitations

Glycobiology(2025)10.1093/glycob/cwaf048

N/A

0DataRank · unranked

20 citations

Natarajan Kannan, Kelley W. Moremen, Chin Huang

Redox regulation and dynamic control of brain-selective kinases BRSK1/2 in the AMPK family through cysteine-based mechanisms

eLife(2025)10.7554/elife.92536.4

N/A

0DataRank · unranked

5 citations

Dominic P. Byrne, Safal Shrestha, Leonard A. Daly, Sally O. Oswald, Samiksha Katiyar +6 more

Deciphering the unique autoregulatory mechanisms and substrate specificity of the understudied DCLK3 kinase linked to neurodegenerative diseases

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110664

N/A

0DataRank · unranked

2 citations

Peng Zhao, Anup Kumar Prasad, Neha Gupta, Nathan Gravel, Tej Shidhaye +4 more

Identification and classification of ion-channels across the tree of life provide functional insights into understudied CALHM channels

eLife(2025)10.7554/elife.106134.2

N/A

0DataRank · unranked

2 citations

Sung Jin Park, Nathan Gravel, Saber Soleymani, Rayna Carter, Kennady Boyd +5 more

Task Splitting and Prompt Engineering for Cypher Query Generation in Domain-Specific Knowledge Graphs

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.23.649790

N/A

0DataRank · unranked

1 citations

Nathan Gravel, Krzysztof Kochut, Natarajan Kannan, Saber Soleymani

Identification and classification of ion-channels across the tree of life provide functional insights into understudied CALHM channels

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.02.10.637530

N/A

0DataRank · unranked

0 citations

Sung Jin Park, Nathan Gravel, Saber Soleymani, Rayna Carter, Kennady Boyd +5 more

Identification and classification of ion channels across the tree of life provide functional insights into understudied CALHM channels

eLife(2025)10.7554/elife.106134

N/A

0DataRank · unranked

0 citations

Sung Jin Park, Nathan Gravel, Saber Soleymani, Rayna Carter, Kennady Boyd +5 more

Author response: Redox Regulation of Brain Selective Kinases BRSK1/2: Implications for Dynamic Control of the Eukaryotic AMPK family through Cys-based mechanisms

(2024)10.7554/elife.92536.3.sa3

N/A

0DataRank · unranked

0 citations

Dominic P. Byrne, Safal Shrestha, Leonard A. Daly, Sally O. Oswald, Samiksha Katiyar +6 more

Distinct pseudokinase domain conformations underlie divergent activation mechanisms among vertebrate MLKL orthologues

Nature Communications(2020)10.1038/s41467-020-16823-3

N/A

0DataRank · unranked

64 citations

Cheree Fitzgibbon, Samuel N. Young, Sarah E. Garnish, Wayland Yeung, Diane Coursier +12 more

Emerging roles of the αC‐β4 loop in protein kinase structure, function, evolution, and disease

IUBMB Life(2020)10.1002/iub.2253

N/A

0DataRank · unranked

46 citations

Zheng Ruan, Natarajan Kannan, Wayland Yeung

Cataloguing the dead: breathing new life into pseudokinase research

FEBS Journal(2020)10.1111/febs.15246

N/A

0DataRank · unranked

60 citations

Dominic P. Byrne, John A. Harris, Natarajan Kannan, Patrick A. Eyers, Safal Shrestha

Mutual antagonism between Hippo signaling and cyclin E drives intracellular pattern formation

The Journal of Cell Biology(2020)10.1083/jcb.202002077

N/A

0DataRank · unranked

14 citations

Wolfgang Maier, Uzoamaka N. Chukka, Michael Choromanski, Chinkyu Lee, Ewa Joachimiak +6 more

Quantitative Structure–Mutation–Activity Relationship Tests (QSMART) model for protein kinase inhibitor response prediction

BMC Bioinformatics(2020)10.1186/s12859-020-03842-6

N/A

0DataRank · unranked

14 citations

Wayland Yeung, Ye Wang, Huimin Cheng, Aarya Venkat, Sheng Li +4 more

Natarajan Kannan

Indexed papers

Top data-sharing exemplar

Papers