Alexandra C. Newton

Also affiliated with University of California San Diego

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 26 papers. Top paper: “Zeta Inhibitory Peptide Disrupts Electrostatic Interactions That Maintain Atypical Protein Kinase C in Its Active Conformation on the Scaffold p62”.

Zeta Inhibitory Peptide Disrupts Electrostatic Interactions That Maintain Atypical Protein Kinase C in Its Active Conformation on the Scaffold p62

Journal of Biological Chemistry(2015)10.1074/jbc.m115.676221

N/A

0.538DataRank · unranked

35 citations

Lei Xie, Kim Dore, Li Xie, Jason C. Del Rio, Charles C. King +8 more

Location-specific inhibition of Akt reveals regulation of mTORC1 activity in the nucleus

Nature Communications(2020)10.1038/s41467-020-19937-w

N/A

0DataRank · unranked

54 citations

Yanghao Zhong, Olivia Molinar‐Inglis, Maya T. Kunkel, Ming‐Yuan Chen, Tengqian Sun +7 more

Hypothesis: Unifying model of domain architecture for conventional and novel protein kinase C isozymes

IUBMB Life(2020)10.1002/iub.2401

N/A

0DataRank · unranked

16 citations

Susan S. Taylor, Alexandra C. Newton, Alexandr P. Kornev, Alexander C. Jones

Pharmacology on Target

Trends in Pharmacological Sciences(2020)10.1016/j.tips.2020.02.002

N/A

0DataRank · unranked

2 citations

Alexandra C. Newton, Agnieszka T. Kawashima

mTORC2 controls the activity of PKC and Akt by phosphorylating a conserved TOR interaction motif

Science Signaling(2021)10.1126/scisignal.abe4509

N/A

0DataRank · unranked

113 citations

Gema Lordén, Jacob M. Wozniak, Andreas Feichtner, Wayland Yeung, Alexandr P. Kornev +13 more

Protein kinase C fusion proteins are paradoxically loss of function in cancer

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.100445

N/A

0DataRank · unranked

52 citations

Maya T. Kunkel, Timothy R. Baffi, Gema Lordén, Corina E. Antal, Sourav Banerjee +2 more

PKCα Is Recruited to Staphylococcus aureus-Containing Phagosomes and Impairs Bacterial Replication by Inhibition of Autophagy

Frontiers in Immunology(2021)10.3389/fimmu.2021.662987

N/A

0DataRank · unranked

11 citations

Alexandra C. Newton, María Isabel Colombo, Maria Celeste Gaurón

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch

Molecular and Cellular Biology(2021)10.1128/mcb.00333-20

N/A

0DataRank · unranked

8 citations

Cassandra J. Wong, Gema Lordén, Charles C. King, Pablo Lara-González, Arshad Desai +3 more

Enhanced Activity of Alzheimer Disease-associated Variant ofProtein Kinase Cα Drives Cognitive Decline

Research Square(2021)10.21203/rs.3.rs-894083/v1

N/A

0DataRank · unranked

1 citations

Jacob M. Wozniak, Kim Doré, Lara E. Dozier, Chelsea Cates‐Gatto, Gentry N. Patrick +5 more

Protein Kinase Cγ Mutations Drive Spinocerebellar Ataxia Type 14 by Impairing Autoinhibition

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.24.449810

N/A

0DataRank · unranked

0 citations

Timothy R. Baffi, Alexandr P. Kornev, Maya T. Kunkel, Mario Malfavon, Donghui Chen +9 more

Enhanced activity of Alzheimer disease-associated variant of protein kinase Cα drives cognitive decline in a mouse model

Nature Communications(2022)10.1038/s41467-022-34679-7

N/A

0DataRank · unranked

44 citations

Jacob M. Wozniak, Kim Doré, Lara E. Dozier, Chelsea Cates‐Gatto, Gentry N. Patrick +5 more

Two Sides of the Same Coin: Protein Kinase C γ in Cancer and Neurodegeneration

Frontiers in Cell and Developmental Biology(2022)10.3389/fcell.2022.929510

N/A

0DataRank · unranked

42 citations

Alexandra C. Newton, Caila A. Pilo

Protein kinase C: release from quarantine by mTORC2

Trends in Biochemical Sciences(2022)10.1016/j.tibs.2022.03.003

N/A

0DataRank · unranked

24 citations

Alexandra C. Newton, Timothy R. Baffi

Fructose-1,6-bisphosphatase is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness

Cell Metabolism(2023)10.1016/j.cmet.2023.03.021

N/A

0DataRank · unranked

38 citations

Yahui Zhu, Kosuke Watari, Maiya Lee, Junlai Liu, Sofia Perez +18 more

Single-residue mutation in protein kinase C toggles between cancer and neurodegeneration

Biochemical Journal(2023)10.1042/bcj20220397

N/A

0DataRank · unranked

5 citations

Alexandr P. Kornev, Jui‐Hung Weng, Gerard Manning, Susan S. Taylor, Alexandra C. Newton +1 more

FBP1 is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.05.531181

N/A

0DataRank · unranked

0 citations

Yahui Zhu, Kosuke Watari, Maiya Lee, Junlai Liu, Sofia Perez +18 more

Single-residue mutation in protein kinase C toggles between cancer and neurodegeneration

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.16.532226

N/A

0DataRank · unranked

0 citations

Alexandr P. Kornev, Jui‐Hung Weng, Gerard Manning, Susan S. Taylor, Alexandra C. Newton +1 more

Post-translational modification-centric base editor screens to assess phosphorylation site functionality in high throughput

Nature Methods(2024)10.1038/s41592-024-02256-z

N/A

0DataRank · unranked

22 citations

Amin Alborzian Deh Sheikh, Matthew Balakar, Alexander C. Jones, Meagan E. Olive, Mudra Hegde +15 more

Sensitive fluorescent biosensor reveals differential subcellular regulation of PKC

Nature Chemical Biology(2024)10.1038/s41589-024-01758-3

N/A

0DataRank · unranked

13 citations

Jing Zhang, Wei Lin, Jinfan Zhang, Alexandra C. Newton, Sohum Mehta +3 more

Cancer-associated mutations in protein kinase C theta are loss-of-function

Biochemical Journal(2024)10.1042/bcj20240148

N/A

0DataRank · unranked

10 citations

Nathan Gravel, Natarajan Kannan, Alexandra C. Newton, Stefanie Hodapp

Sensitive Fluorescent Biosensor Reveals Differential Subcellular Regulation of PKC

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.29.587373

N/A

0DataRank · unranked

5 citations

Jing Zhang, Wei Lin, Jin-fan Zhang, Alexandra C. Newton, Sohum Mehta +3 more

Mutant prion protein enhances NMDA receptor activity, activates PKC, and triggers rapid excitotoxicity in mice

Journal of Clinical Investigation(2025)10.1172/jci186432

N/A

0DataRank · unranked

6 citations

Julia A. Callender, Joshua E. Mayfield, Daniel B. McClatchy, Daniel Ojeda-Juárez, Mahsa Pourhamzeh +26 more

C-spine mutations of protein kinase C and Akt as a novel generalizable approach to create stable pseudokinases

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110921

N/A

0DataRank · unranked

2 citations

Tiffany Kao, Jian Wu, Nileeka Balasuriya, Corina E. Antal, Susan S. Taylor +2 more

Protein kinase C eta enhances Golgi-localized signaling and is associated with Alzheimer’s disease using a recessive mode of inheritance

medRxiv(2025)10.1101/2025.05.13.25327562

N/A

0DataRank · unranked

2 citations

Dmitry Prokopenko, Sanghun Lee, Sarah A. Wolfe, Julian Hecker, Julian Willett +15 more

Scaffolding of atypical protein kinase C to p62 is disrupted by the pseudosubstrate peptide ZIP (802.4)

The FASEB Journal(2014)10.1096/fasebj.28.1_supplement.802.4

N/A

0DataRank · unranked

0 citations

Lei Xie, Li Xie, Philip E. Bourne, Alexandra C. Newton, Li‐Chun Tsai

A Catalytically Inactive Protein Kinase C alpha Mutation Drives Chordoid Glioma by Pathway Rewiring

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.30.657104

N/A

0DataRank · unranked

1 citations

Hannah Tovell, Selina Schwaighofer, Timothy R. Baffi, Janan Arslan, Quentin Letourneur +15 more