Amr H. Sawalha

Also affiliated with Children's Hospital of Pittsburgh

MedicineImmunology and MicrobiologyBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 42 papers. Top paper: “COVID-19: A review of therapeutic strategies and vaccine candidates”.

COVID-19: A review of therapeutic strategies and vaccine candidates

Clinical Immunology(2020)10.1016/j.clim.2020.108634

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291 citations

Matlock A. Jeffries, Amr H. Sawalha, Vladislav Izda

Epigenetic dysregulation of ACE2 and interferon-regulated genes might suggest increased COVID-19 susceptibility and severity in lupus patients

Clinical Immunology(2020)10.1016/j.clim.2020.108410

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271 citations

Ming Zhao, Patrick Coit, Qianjin Lu, Amr H. Sawalha

A longitudinal and transancestral analysis of DNA methylation patterns and disease activity in lupus patients

JCI Insight(2020)10.1172/jci.insight.143654

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66 citations

Lourdes Ortiz‐Fernández, Emily E. Lewis, W. Joseph McCune, Kathleen Maksimowicz‐McKinnon, Amr H. Sawalha +1 more

Glycoprotein nonmetastatic melanoma protein B: A key mediator and an emerging therapeutic target in autoimmune diseases

The FASEB Journal(2020)10.1096/fj.202000651

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57 citations

Amr H. Sawalha, Pei‐Suen Tsou

Genetic variability in the expression of the SARS-CoV-2 host cell entry factors across populations

Genes and Immunity(2020)10.1038/s41435-020-0107-7

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57 citations

Amr H. Sawalha, Lourdes Ortiz‐Fernández

Patients with lupus are not protected from COVID-19

Annals of the Rheumatic Diseases(2020)10.1136/annrheumdis-2020-217656

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14 citations

Amr H. Sawalha

DNA methylation patterns and disease activity in a longitudinal cohort of lupus patients

medRxiv(2020)10.1101/2020.09.18.20197525

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0 citations

Lourdes Ortiz‐Fernández, Emily E. Lewis, W. Joseph McCune, Kathleen Maksimowicz‐McKinnon, Amr H. Sawalha +1 more

Clinical subgroup clustering analysis in a systemic lupus erythematosus cohort from Western Pennsylvania

medRxiv(2020)10.1101/2020.11.12.20230789

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0 citations

Lacy Ruffalo, Amr H. Sawalha, Patrick Coit

Genetics of Behçet's Disease: Functional Genetic Analysis and Estimating Disease Heritability

Frontiers in Medicine(2021)10.3389/fmed.2021.625710

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44 citations

Amr H. Sawalha, Lourdes Ortiz‐Fernández

Genetic Association of a Gain‐of‐Function IFNGR1 Polymorphism and the Intergenic Region LNCAROD/DKK1 With Behçet’s Disease

Arthritis & Rheumatology(2021)10.1002/art.41637

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28 citations

Patrick Coit, Vuslat Yılmaz, Sibel P. Yentür, Fatma Alıbaz-Öner, Kenan Aksu +32 more

HLA-DRB1 allelic epitopes that associate with autoimmune disease risk or protection activate reciprocal macrophage polarization

Scientific Reports(2021)10.1038/s41598-021-82195-3

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26 citations

Bruna Miglioranza Scavuzzi, Sarah Veloso Nogueira, Frederick W. Miller, Amr H. Sawalha, Joseph Holoshitz +1 more

Genome‐Wide Reduction in Chromatin Accessibility and Unique Transcription Factor Footprints in Endothelial Cells and Fibroblasts in Scleroderma Skin

Arthritis & Rheumatology(2021)10.1002/art.41694

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23 citations

Pamela J. Palisoc, Mustafa Ali, Dinesh Khanna, Amr H. Sawalha, Pei‐Suen Tsou

Systemic lupus erythematosus as a genetic disease

Clinical Immunology(2022)10.1016/j.clim.2022.108953

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61 citations

Amr H. Sawalha, Isaac T. W. Harley

Centromere defects, chromosome instability, and cGAS-STING activation in systemic sclerosis

Nature Communications(2022)10.1038/s41467-022-34775-8

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44 citations

Mark H. Kaplan, Dinesh Khanna, Preston M. McCourt, Anjan K. Saha, Pei‐Suen Tsou +7 more

Sex-specific analysis in Behçet's disease reveals higher genetic risk in male patients

Journal of Autoimmunity(2022)10.1016/j.jaut.2022.102882

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32 citations

Lourdes Ortiz‐Fernández, Patrick Coit, Vuslat Yılmaz, Sibel P. Yentür, Fatma Alıbaz-Öner +27 more

Post-GWAS functional analysis identifies CUX1 as a regulator of p16INK4a and cellular senescence

Nature Aging(2022)10.1038/s43587-022-00177-0

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25 citations

Wei Sun, Ting Wu, Meijuan Zou, Sathish Babu Vasamsetti, Xiaoyu Zhang +15 more

Inhibition of bromodomain extraterminal histone readers alleviates skin fibrosis in experimental models of scleroderma

JCI Insight(2022)10.1172/jci.insight.150871

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23 citations

Mikel Gurrea‐Rubio, M. Asif Amin, Phillip L. Campbell, Qi Wu, Megan N. Mattichak +14 more

The lupus susceptibility allele DRB1*03:01 encodes a disease-driving epitope

Communications Biology(2022)10.1038/s42003-022-03717-x

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21 citations

Vincent van Drongelen, Bhavneet Kaur, Jennifer Callahan Fox, Jianhua Liu, Raquel Agnelli Mesquita‐Ferrari +7 more

Hypomethylation of miR-17-92 cluster in lupus T cells and no significant role for genetic factors in the lupus-associated DNA methylation signature

Annals of the Rheumatic Diseases(2022)10.1136/annrheumdis-2022-222656

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14 citations

Xiavan Roopnarinesingh, Lourdes Ortiz‐Fernández, Kathleen McKinnon-Maksimowicz, Emily E. Lewis, Joan T. Merrill +4 more

Reduced SPAG17 Expression in Systemic Sclerosis Triggers Myofibroblast Transition and Drives Fibrosis

Journal of Investigative Dermatology(2022)10.1016/j.jid.2022.08.052

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14 citations

Elisha Roberson, Bo Shi, Shervin Assassi, Brian Skaug, Fred Lee +18 more

Sex-based comparison of CD4+ T cell DNA methylation in lupus reveals proinflammatory epigenetic changes in men

Clinical Immunology(2022)10.1016/j.clim.2022.109116

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6 citations

Patrick Coit, Amr H. Sawalha, Mustafa Ali

Hypomethylation of miR-17-92 cluster in lupus T cells and no significant role for genetic factors in the lupus-associated DNA methylation signature

medRxiv(2022)10.1101/2022.02.21.22271293

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1 citations

Xiavan Roopnarinesingh, Lourdes Ortiz‐Fernández, Kathleen Maksimowicz‐McKinnon, Emily E. Lewis, Joan T. Merrill +4 more

The lupus susceptibility allele DRB1*03:01 encodes a disease-driving epitope

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.31.494172

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1 citations

Vincent van Drongelen, Bhavneet Kaur, Jennifer Callahan Fox, Jianhua Liu, Raquel Agnelli Mesquita‐Ferrari +7 more

Ezh2 knockout in B cells impairs plasmablast differentiation and ameliorates lupus-like disease in MRL/ lpr mice

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.21.500990

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0 citations

Mikhail G. Dozmorov, Colleen E Strohlein, Sheldon Bastacky, Amr H. Sawalha, Xiaoqing Zheng

Regulation of Photosensitivity by the Hippo Pathway in Lupus Skin

Arthritis & Rheumatology(2023)10.1002/art.42460

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20 citations

Patrick Coit, Bin Xu, Amanda Victory, Mehrnaz Gharaee‐Kermani, Shannon N. Estadt +12 more

Clinical trait-specific genetic analysis in Behçet's disease identifies novel loci associated with ocular and neurological involvement

Clinical Immunology(2023)10.1016/j.clim.2023.109657

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13 citations

Deren Esencan, Fatma Alıbaz-Öner, Ayşe Çefle, Ayten Yazıcı, Nurşen Düzgün +10 more

Ezh2 Knockout in B Cells Impairs Plasmablast Differentiation and Ameliorates Lupus‐like Disease in MRL/lpr Mice

Arthritis & Rheumatology(2023)10.1002/art.42492

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12 citations

Mikhail G. Dozmorov, Colleen E Strohlein, Sheldon Bastacky, Amr H. Sawalha, Xiaoqing Zheng

Phenotype Risk Score but Not Genetic Risk Score Aids in Identifying Individuals With Systemic Lupus Erythematosus in the Electronic Health Record

Arthritis & Rheumatology(2023)10.1002/art.42544

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5 citations

Lee Wheless, Alex Camai, Sarah Green, Bryan Han, Anish Katta +3 more

A genome-wide association study suggests new susceptibility loci for primary antiphospholipid syndrome

medRxiv(2023)10.1101/2023.12.05.23299396

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1 citations

Manuel Martínez‐Bueno, María Orietta Borghi, Guillermo Pons‐Estel, Guillermo Reales, Yu Zuo +13 more

Neutrophil glucose flux as a therapeutic target in antiphospholipid syndrome

Journal of Clinical Investigation(2024)10.1172/jci169893

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15 citations

Alyssa Harbaugh, Somanathapura K. NaveenKumar, Megan D. Radyk, Christine E. Rysenga, Kaitlyn Sabb +15 more

A Genome‐Wide Association Study Suggests New Susceptibility Loci for Primary Antiphospholipid Syndrome

Arthritis & Rheumatology(2024)10.1002/art.42947

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10 citations

Manuel Martínez‐Bueno, María Orietta Borghi, Guillermo Pons‐Estel, Guillermo Reales, Yu Zuo +13 more

Intestinal permeability correlates with disease activity and DNA methylation changes in lupus patients

Clinical Immunology(2024)10.1016/j.clim.2024.110173

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10 citations

Desiré Casares‐Marfil, Amr H. Sawalha, Mckenna M Bowes

Inducible deletion of Ezh2 in CD4+ T cells inhibits kidney T cell infiltration and prevents interstitial nephritis in MRL/lpr lupus-prone mice

iScience(2024)10.1016/j.isci.2024.111114

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3 citations

Mikhail G. Dozmorov, Luis Espinoza, Mckenna M Bowes, Sheldon Bastacky, Amr H. Sawalha +1 more

Functional and Practical Insights Into the Genetic Basis of Takayasu Arteritis

ACR Open Rheumatology(2024)10.1002/acr2.11766

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6 citations

Amr H. Sawalha, Desiré Casares‐Marfil

Unraveling the immunomodulatory impact of hydroxychloroquine on peripheral T cells using single-cell RNA sequencing

Journal of Autoimmunity(2024)10.1016/j.jaut.2024.103324

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4 citations

Luis Espinosa, Amr H. Sawalha, Huizhong Long

Childhood-onset systemic lupus erythematosus: A descriptive and comparative study of clinical, laboratory, and treatment characteristics in two populations

Lupus(2024)10.1177/09612033241265975

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2 citations

Deren Esencan, Vafa Guliyeva, Selen Duygu Arık, Şeyma Türkmen, Sezgin Şahin +7 more

Rare Turner syndrome and lupus coexistence with insights from DNA methylation patterns

Clinical Immunology(2024)10.1016/j.clim.2024.110310

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1 citations

Desiré Casares‐Marfil, Sezgin Şahin, Özgür Kasapçopur, Betül Sözeri, Nuray Aktay Ayaz +2 more

Genetic Analysis of Asymptomatic Antinuclear Antibody Production

Arthritis & Rheumatology(2024)10.1002/art.43032

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5 citations

Desiré Casares‐Marfil, Amr H. Sawalha, Mehmet Hocaoǧlu

Inducible deletion of Ezh2 in CD4+ T cells inhibits kidney T cell infiltration and prevents interstitial nephritis in MRL/ lpr lupus-prone mice

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.04.583401

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0 citations

Mikhail G. Dozmorov, Luis Espinoza, Mckenna M Bowes, Sheldon Bastacky, Amr H. Sawalha +1 more

Integrated analysis of polygenic and environmental risk scores for late-onset systemic lupus erythematosus

Journal of Autoimmunity(2025)10.1016/j.jaut.2025.103441

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6 citations

Amr H. Sawalha, Mehmet Hocaoǧlu

The role of epigenetic modifications in systemic autoinflammatory diseases

Current Opinion in Immunology(2025)10.1016/j.coi.2025.102599

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1 citations

Desiré Casares‐Marfil, Erkan Demirkaya, Amr H. Sawalha, Kader Cetin Gedik

DNA Methylation Profiling in Childhood-Onset Lupus Reveals Distinct Epigenetic Clusters and Suggests Epigenetic Drivers of Disease Activity

medRxiv(2025)10.1101/2025.09.30.25337006

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0 citations

Gülşah Kavrul Kayaalp, Vafa Guliyeva, Özlem Akgün, Şeyma Türkmen, Elif Kılıç Könte +9 more