Omar Abdel-Wahab

Also affiliated with Kettering University

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 104 papers. Top paper: “Improved prediction of immune checkpoint blockade efficacy across multiple cancer types”.

Improved prediction of immune checkpoint blockade efficacy across multiple cancer types

Nature Biotechnology(2021)10.1038/s41587-021-01070-8

N/A

7.3DataRank · unranked

272 citations

Seong‐Keun Yoo, Cristina Valero, Alessandro Pastore, Chirag Krishna, Mark Lee +29 more

Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer

Cancer Cell(2020)10.1016/j.ccell.2020.05.010

N/A

4.8DataRank · unranked

164 citations

Alex Penson, Ram Kannan, Hana Cho, Chun‐Hao Pan, Rohit K. Singh +39 more

Zanubrutinib, obinutuzumab, and venetoclax with minimal residual disease-driven discontinuation in previously untreated patients with chronic lymphocytic leukaemia or small lymphocytic lymphoma: a multicentre, single-arm, phase 2 trial

The Lancet Haematology(2021)10.1016/s2352-3026(21)00307-0

N/A

3.8DataRank · unranked

110 citations

Anthony R Mato, Ahmet Dogan, Venkatraman E Seshan, Erel Joffe, Kelsey Flaherty +41 more

Single-cell multi-omics defines the cell-type-specific impact of splicing aberrations in human hematopoietic clonal outgrowths

Cell stem cell(2023)10.1016/j.stem.2023.07.012

N/A

1.5DataRank · unranked

63 citations

Paulina Chamely, Allegra G. Hawkins, Robert F. Stanley, Ariel D. Swett, Saravanan Ganesan +29 more

E7820, an anti-cancer sulfonamide, degrades RBM39 in patients with splicing factor mutant myeloid malignancies: a phase II clinical trial

Leukemia(2023)10.1038/s41375-023-02050-4

N/A

0.982DataRank · unranked

52 citations

Maximilian Stahl, Justin Taylor, Xiaoli Mi, Namrata S. Chandhok, Justin M. Watts +11 more

Finding consistency in classifications of myeloid neoplasms: a perspective on behalf of the International Workshop for Myelodysplastic Syndromes

Leukemia(2022)10.1038/s41375-022-01724-9

N/A

0.926DataRank · unranked

28 citations

Jan Philipp Bewersdorf, Rena Buckstein, Mikkael A. Sekeres, David P. Steensma, Uwe Platzbecker +44 more

Safety and activity of selinexor in patients with myelodysplastic syndromes or oligoblastic acute myeloid leukaemia refractory to hypomethylating agents: a single-centre, single-arm, phase 2 trial

The Lancet Haematology(2020)10.1016/s2352-3026(20)30209-x

N/A

0.843DataRank · unranked

21 citations

Xiaoli Mi, Alexander Penson, Stella Paffenholz, Kelsey Alvarez, Allison Sigler +10 more

ARAF protein kinase activates RAS by antagonizing its binding to RASGAP NF1

Molecular Cell(2022)10.1016/j.molcel.2022.04.034

N/A

0.841DataRank · unranked

23 citations

Radha Mukherjee, Rona Yaeger, Jieun Son, Jianing Xu, Na Na +22 more

BRD9 determines the cell fate of hematopoietic stem cells by regulating chromatin state

Nature Communications(2023)10.1038/s41467-023-44081-6

N/A

0.822DataRank · unranked

34 citations

Shinji Kondo, Masaki Nomura, Shinichiro Kato, Koutarou Nishimura, Weijia Zang +25 more

Neurologic and oncologic features of Erdheim–Chester disease: a 30-patient series

Neuro-Oncology(2020)10.1093/neuonc/noaa008

N/A

0.617DataRank · unranked

60 citations

Vaios Hatzoglou, Gary A. Ulaner, Raajit K. Rampal, David M. Hyman, Omar Abdel-Wahab +10 more

NUDT21 limits CD19 levels through alternative mRNA polyadenylation in B cell acute lymphoblastic leukemia

Nature Immunology(2022)10.1038/s41590-022-01314-y

N/A

0.614DataRank · unranked

59 citations

Soobeom Lee, Eric Wang, Anna K. Lee, Alexis Talbot, Chao Ma +15 more

Measurable residual disease by flow cytometry in acute myeloid leukemia is prognostic, independent of genomic profiling

Leukemia Research(2022)10.1016/j.leukres.2022.106971

N/A

0.613DataRank · unranked

9 citations

Zhuoxin Sun, Timour Baslan, Yanming Zhang, Mithat Gönen, Omar Abdel-Wahab +13 more

Impaired Proteolysis of Noncanonical RAS Proteins Drives Clonal Hematopoietic Transformation

Cancer Discovery(2022)10.1158/2159-8290.cd-21-1631

N/A

0.542DataRank · unranked

36 citations

Rahul S. Vedula, Antonio Cuevas-Navarro, Bin Lü, Simon J. Hogg, Eric Wang +22 more

An agenda to advance research in myelodysplastic syndromes: a TOP 10 priority list from the first international workshop in MDS

Blood Advances(2022)10.1182/bloodadvances.2022008747

N/A

0.525DataRank · unranked

11 citations

Omar Abdel-Wahab, Andrew H. Wei, Michael R. Savona, Mina L. Xu, Zhuoer Xie +45 more

Induction of a mismatch repair deficient genotype by tailored chemical mutagenesis in experimental models of cancer

Cancer Cell(2025)10.1016/j.ccell.2025.05.010

N/A

0.385DataRank · unranked

11 citations

Mitesh Patel, Oliver Artz, Georgios Vlachos, Shrey Patel, Omar Hayatt +45 more

Role of clonal inflammatory microglia in histiocytosis-associated neurodegeneration

Neuron(2025)10.1016/j.neuron.2025.02.007

N/A

0.375DataRank · unranked

10 citations

Stamatina Fragkogianni, Maria Pokrovskii, Carina Meyer, Estibaliz Lopez-Rodrigo, Yang Hu +32 more

Proteomic discovery of chemical probes that perturb protein complexes in human cells

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.12.12.520090

N/A

0.373DataRank · unranked

11 citations

Jarrett R. Remsberg, Martin G. Jaeger, Katherine Rothamel, Hsuan-Lin Her, Kristen E. DeMeester +30 more

A microglia clonal inflammatory disorder in Alzheimer’s disease

eLife(2024)10.7554/elife.96519

N/A

0.363DataRank · unranked

7 citations

Stamatina Fragkogianni, Leslie Weber, Tomi Lazarov, Yang Hu, Samantha Y. Hayashi +21 more

A microglia clonal inflammatory disorder in Alzheimer’s Disease

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.25.577216

N/A

0.334DataRank · unranked

5 citations

Stamatina Fragkogianni, Leslie Weber, Tomi Lazarov, Yang Hu, Samantha Y. Hayashi +21 more

Inherited resilience to clonal hematopoiesis by modifying stem cell RNA regulation

Science(2026)10.1126/science.adx4174

N/A

0.312DataRank · unranked

7 citations

Mateusz Antoszewski, Xueqin Xie, Yash Pershad, Uma P. Arora, Chi-Lam Poon +23 more

Phase I first-in-human dose escalation study of the oral casein kinase 1α and cyclin dependent kinase 7/9 inhibitor BTX A51 in advanced MDS and AML

Journal of Hematology & Oncology(2025)10.1186/s13045-025-01724-z

N/A

0.254DataRank · unranked

4 citations

Wenbin Xiao, Gautam Borthakur, Le Xuan Truong Nguyen, Melissa Valerio, Avanthika Venkatachalam +11 more

A microglia clonal inflammatory disorder in Alzheimer’s Disease

eLife(2024)10.7554/elife.96519.1

N/A

0.104DataRank · unranked

1 citations

Stamatina Fragkogianni, Leslie Weber, Tomi Lazarov, Yang Hu, Samantha Y. Hayashi +21 more

Single-cell multi-omics of human clonal hematopoiesis reveals that DNMT3A R882 mutations perturb early progenitor states through selective hypomethylation

Nature Genetics(2022)10.1038/s41588-022-01179-9

N/A

0DataRank · unranked

136 citations

Neville Dusaj, Franco Izzo, Rekha Murali, Robert M. Myers, Tarek H. Mouhieddine +12 more

The Impact of Inflammation-Induced Tumor Plasticity during Myeloid Transformation

Cancer Discovery(2022)10.1158/2159-8290.cd-21-1146

N/A

0DataRank · unranked

95 citations

Geraldine Cayanan, Sanam Loghavi, Igor Dolgalev, Emmett M. Leddin, Christian E. Loo +19 more

Modulation of RNA splicing enhances response to BCL2 inhibition in leukemia

Cancer Cell(2022)10.1016/j.ccell.2022.12.002

N/A

0DataRank · unranked

78 citations

Jose Mario Bello Pineda, Won Jun Kim, Sisi Chen, Jessie Bourcier, Maximilian Stahl +22 more

Synthetic introns enable splicing factor mutation-dependent targeting of cancer cells

Nature Biotechnology(2022)10.1038/s41587-022-01224-2

N/A

0DataRank · unranked

63 citations

Salima Benbarche, Bo Liu, Joseph Pangallo, Sisi Chen, Maximilian Stahl +15 more

Molecular predictors of immunophenotypic measurable residual disease clearance in acute myeloid leukemia

American Journal of Hematology(2022)10.1002/ajh.26757

N/A

0DataRank · unranked

25 citations

Andriy Derkach, Noushin Farnoud, Jan Philipp Bewersdorf, Troy M. Robinson, Christopher Famulare +35 more

Aberrant EVI1 splicing contributes to EVI1-rearranged leukemia

Blood(2022)10.1182/blood.2021015325

N/A

0DataRank · unranked

24 citations

Taizo A. Nakano, Masaki Nomura, Hiromi Yamazaki, Jan Philipp Bewersdorf, Roger Mulet‐Lazaro +26 more

Enhancing CD19 Chimeric Antigen Receptor T Cells Through Memory-Enriched T Cells

Clinical Cancer Research(2022)10.1158/1078-0432.ccr-22-3232

N/A

0DataRank · unranked

7 citations

Omar Abdel-Wahab, Ettaib El Marabti

Translating recent advances in the pathogenesis of acute myeloid leukemia to the clinic

Genes & Development(2022)10.1101/gad.349368.122

N/A

0DataRank · unranked

55 citations

Omar Abdel-Wahab, Jan Philipp Bewersdorf

Single-cell multi-omics of human clonal hematopoiesis reveals that DNMT3A R882 mutations perturb early progenitor states through selective hypomethylation

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.14.476225

N/A

0DataRank · unranked

10 citations

Neville Dusaj, Franco Izzo, Rekha Murali, Robert M. Myers, Tarek H. Mouhieddine +12 more

Integrated Single-Cell Genotyping and Chromatin Accessibility Charts JAK2 V617F Human Hematopoietic Differentiation

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.11.491515

N/A

0DataRank · unranked

10 citations

Franco Izzo, Sanjay Kottapalli, Tamara Prieto, Andrew Dunbar, Robert L. Bowman +15 more

Single-cell multi-omics defines the cell-type specific impact of splicing aberrations in human hematopoietic clonal outgrowths

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.08.495292

N/A

0DataRank · unranked

9 citations

Paulina Chamely, Allegra G. Hawkins, Mariela Cortés-López, Ariel D. Swett, Saravanan Ganesan +21 more

Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS/AML

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.26.509430

N/A

0DataRank · unranked

2 citations

Benjamín Martín, William C. Doyle, Rebecca A. Gorelov, Melanie Donahue, Johann Christoph Jann +8 more

Enhanced clinical assessment of hematologic malignancies through routine paired tumor:normal sequencing

medRxiv(2022)10.1101/2022.10.03.22280675

N/A

0DataRank · unranked

1 citations

Mark D. Ewalt, Gowtham Jayakumaran, Iwona Kiecka, Anita S. Bowman, JinJuan Yao +50 more

Enhanced clinical assessment of hematologic malignancies through routine paired tumor:normal sequencing

Research Square(2022)10.21203/rs.3.rs-2094202/v1

N/A

0DataRank · unranked

0 citations

Mark D. Ewalt, Gowtham Jayakumaran, Iwona Kiecka, Anita S. Bowman, JinJuan Yao +50 more

Interaction between myelodysplasia-related gene mutations and ontogeny in acute myeloid leukemia: an appraisal of the new WHO and IC classifications and ELN risk stratification

medRxiv(2022)10.1101/2022.12.26.22283876

N/A

0DataRank · unranked

0 citations

David Nemirovsky, Christopher Famulare, Noushin Farnoud, Abhinita Mohanty, Zoe S. Stone-Molloy +22 more

Proteomic discovery of chemical probes that perturb protein complexes in human cells

Molecular Cell(2023)10.1016/j.molcel.2023.03.026

N/A

0DataRank · unranked

94 citations

Jarrett R. Remsberg, Martin G. Jaeger, Katherine Rothamel, Hsuan-Lin Her, Kristen E. DeMeester +30 more

SRSF2 plays an unexpected role as reader of m5C on mRNA, linking epitranscriptomics to cancer

Molecular Cell(2023)10.1016/j.molcel.2023.11.003

N/A

0DataRank · unranked

77 citations

Martin Bizet, Christelle Soares Da Costa, Frédéric Murisier, Eric James de Bony, Mengke Wang +25 more

Classification, risk stratification and response assessment in myelodysplastic syndromes/neoplasms (MDS): A state-of-the-art report on behalf of the International Consortium for MDS (icMDS)

Blood Reviews(2023)10.1016/j.blre.2023.101128

N/A

0DataRank · unranked

31 citations

Jan Philipp Bewersdorf, Zhuoer Xie, Matteo Giovanni Della Porta, Rami S. Komrokji, Mina L. Xu +43 more

Enhanced clinical assessment of hematologic malignancies through routine paired tumor and normal sequencing

Nature Communications(2023)10.1038/s41467-023-42585-9

N/A

0DataRank · unranked

29 citations

Mark D. Ewalt, Gowtham Jayakumaran, Iwona Kiecka, Anita S. Bowman, JinJuan Yao +50 more

Systematic evaluation of AML-associated antigens identifies anti-U5 SNRNP200 therapeutic antibodies for the treatment of acute myeloid leukemia

Nature Cancer(2023)10.1038/s43018-023-00656-2

N/A

0DataRank · unranked

23 citations

Jahan Rahman, Caroline Erickson, Eric Wang, Mara Monetti, Zhuoning Li +21 more

Outcomes after interruption of targeted therapy in patients with histiocytic neoplasms

British Journal of Haematology(2023)10.1111/bjh.18964

N/A

0DataRank · unranked

22 citations

Benjamin H. Durham, Mariko Yabe, Kseniya Petrova‐Drus, Jasmine H. Francis, Raajit K. Rampal +6 more

Interaction between myelodysplasia-related gene mutations and ontogeny in acute myeloid leukemia

Blood Advances(2023)10.1182/bloodadvances.2023009675

N/A

0DataRank · unranked

19 citations

David Nemirovsky, Christopher Famulare, Noushin Farnoud, Abhinita Mohanty, Zoe S. Stone-Molloy +22 more

Current landscape of translational and clinical research in myelodysplastic syndromes/neoplasms (MDS): Proceedings from the 1st International Workshop on MDS (iwMDS) Of the International Consortium for MDS (icMDS)

Blood Reviews(2023)10.1016/j.blre.2023.101072

N/A

0DataRank · unranked

18 citations

Zhuoer Xie, Rafael Bejar, Uma Borate, Jacqueline Boultwood, Andrew M. Brunner +37 more

SRSF2 mutation cooperates with ASXL1 truncated alteration to accelerate leukemogenesis

Leukemia(2023)10.1038/s41375-023-02094-6

N/A

0DataRank · unranked

12 citations

Guo Ge, Shi Chen, Jiaojiao Bai, Ivan P. Rubalcava, Hui Yang +9 more

CSF1R inhibition for histiocytic neoplasm with CBL mutations refractory to MEK1/2 inhibition

Leukemia(2023)10.1038/s41375-023-01947-4

N/A

0DataRank · unranked

10 citations

Jasmine H. Francis, Mario E. Lacouture, Veronica Rotemberg, Mariko Yabe, Kseniya Petrova‐Drus +5 more

Mutant PIK3CA is a targetable driver alteration in histiocytic neoplasms

Blood Advances(2023)10.1182/bloodadvances.2022009349

N/A

0DataRank · unranked

10 citations

Oshrat Hershkovitz‐Rokah, Omar Abdel-Wahab, Mariko Yabe, Young Rock Chung, Gilad Itchaki +10 more

Targeting lysine demethylase 6B ameliorates ASXL1 truncation–mediated myeloid malignancies in preclinical models

Journal of Clinical Investigation(2023)10.1172/jci163964

N/A

0DataRank · unranked

10 citations

Peng Zhang, Pinpin Sui, Shi Chen, Hui Yang, Ying Guo +13 more

Genome‐Wide Association Study Identifies the First Germline Genetic Variant Associated With Erdheim‐Chester Disease

Arthritis & Rheumatology(2023)10.1002/art.42673

N/A

0DataRank · unranked

6 citations

Ana Márquez, Francesco Pegoraro, Lourdes Ortiz‐Fernández, Marialbert Acosta‐Herrera, Martin Kerick +19 more

Covalent Targeting of Splicing in T Cells

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.18.572199

N/A

0DataRank · unranked

5 citations

Hiroyuki Kojima, Nathalie Ropek, Charles David Warren, Tiffany L. Zhang, Simon J. Hogg +9 more

A mitochondrial surveillance mechanism activated by SRSF2 mutations in hematologic malignancies

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.25.546449

N/A

0DataRank · unranked

1 citations

Sudhish A. Devadiga, Robert F. Stanley, Ryan Morrow, Kevin A. Janssen, Mathieu Quesnel-Vallières +11 more

Data from Impaired Proteolysis of Noncanonical RAS Proteins Drives Clonal Hematopoietic Transformation

(2023)10.1158/2159-8290.c.6549783

N/A

0DataRank · unranked

0 citations

Rahul S. Vedula, Antonio Cuevas-Navarro, Bin Lü, Simon J. Hogg, Eric Wang +22 more

Drug‐resistance mutations in BTK occur in distinct enzymatic classes and are overcome by BTK degradation

Hematological Oncology(2023)10.1002/hon.3164_403

N/A

0DataRank · unranked

0 citations

J. Bourcie, Arun Sondhi, Jacob Jahn, Alvaro J. Alencar, Omar Abdel-Wahab +2 more

Kinase-impaired BTK mutations are susceptible to clinical-stage BTK and IKZF1/3 degrader NX-2127

Science(2024)10.1126/science.adi5798

N/A

0DataRank · unranked

152 citations

Jessie Bourcier, Mark Noviski, Hao Lu, Meghan C. Thompson, Alexandra Chirino +48 more

Molecular impact of mutations in RNA splicing factors in cancer

Molecular Cell(2024)10.1016/j.molcel.2024.07.019

N/A

0DataRank · unranked

69 citations

Yuxi Ai, Omar Abdel-Wahab, Qian Zhang

Mapping genotypes to chromatin accessibility profiles in single cells

Nature(2024)10.1038/s41586-024-07388-y

N/A

0DataRank · unranked

60 citations

Robert M. Myers, Saravanan Ganesan, Levan Mekerishvili, Sanjay Kottapalli, Tamara Prieto +22 more

GPATCH8 modulates mutant SF3B1 mis-splicing and pathogenicity in hematologic malignancies

Molecular Cell(2024)10.1016/j.molcel.2024.04.006

N/A

0DataRank · unranked

40 citations

Jose Mario Bello Pineda, Laura Baquero Galvis, Jeetayu Biswas, Bo Liu, Eric Wang +19 more

Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS and AML

Science Translational Medicine(2024)10.1126/scitranslmed.ade2774

N/A

0DataRank · unranked

38 citations

Benjamín Martín, William C. Doyle, Sofia Neaher, Caroline A. Conway, C Pitton +13 more

New Means and Challenges in the Targeting of BTK

Clinical Cancer Research(2024)10.1158/1078-0432.ccr-23-0409

N/A

0DataRank · unranked

26 citations

Anya K. Sondhi, Omar Abdel-Wahab, Justin Taylor, Vindhya Nawaratne

A mitochondrial surveillance mechanism activated by SRSF2 mutations in hematologic malignancies

Journal of Clinical Investigation(2024)10.1172/jci175619

N/A

0DataRank · unranked

19 citations

Sudhish A. Devadiga, Robert F. Stanley, Ryan Morrow, Kevin A. Janssen, Mathieu Quesnel-Vallières +11 more

Covalent targeting of splicing in T cells

Cell chemical biology(2024)10.1016/j.chembiol.2024.10.010

N/A

0DataRank · unranked

16 citations

Hiroyuki Kojima, Nathalie Ropek, Charles David Warren, Tiffany L. Zhang, Simon J. Hogg +10 more

Contemporary Approach to the Diagnosis and Classification of Myelodysplastic Neoplasms/Syndromes—Recommendations From the International Consortium for Myelodysplastic Neoplasms/Syndromes (MDS [icMDS])

Modern Pathology(2024)10.1016/j.modpat.2024.100615

N/A

0DataRank · unranked

12 citations

Savanah D. Gisriel, Amer M. Zeidan, John M. Bennett, Rafael Bejar, Jan Philipp Bewersdorf +48 more

Aberrant pre-mRNA processing in cancer

The Journal of Experimental Medicine(2024)10.1084/jem.20230891

N/A

0DataRank · unranked

8 citations

Leora Boussi, Eytan M. Stein, Omar Abdel-Wahab, Jeetayu Biswas

Mixed histiocytic neoplasms: A multicentre series revealing diverse somatic mutations and responses to targeted therapy

British Journal of Haematology(2024)10.1111/bjh.19462

N/A

0DataRank · unranked

16 citations

Benjamin H. Durham, Anne S. Reiner, Mariko Yabe, Kseniya Petrova‐Drus, Ahmet Doǧan +26 more

Augmenting CAR T-cell Functions with LIGHT

Cancer Immunology Research(2024)10.1158/2326-6066.cir-24-0246

N/A

0DataRank · unranked

4 citations

Kento Tanaka, Xiaoli Mi, Vinagolu K. Rajasekhar, Jonathan F. Khan, Sarah Yoo +15 more

Disruption of cotranscriptional splicing suggests RBM39 is a therapeutic target in acute lymphoblastic leukemia

Blood(2024)10.1182/blood.2024024281

N/A

0DataRank · unranked

4 citations

Ethan Harris, Jacquelyn Myers, Rashid Mehmood, Anitria Cotton, Hazheen K. Shirnekhi +16 more

Therapeutic strategies targeting aberrant RNA splicing in myeloid malignancies

British Journal of Haematology(2024)10.1111/bjh.19826

N/A

0DataRank · unranked

4 citations

Jeetayu Biswas, Omar Abdel-Wahab, Eytan M. Stein, Leora Boussi

SWI/SNF regulation of germinal center fate and lymphomagenesis

Cancer Cell(2024)10.1016/j.ccell.2024.02.006

N/A

0DataRank · unranked

2 citations

Omar Abdel-Wahab, Quinlan Sievers

A microglia clonal inflammatory disorder in Alzheimer’s Disease

eLife(2024)10.7554/elife.96519.2

N/A

0DataRank · unranked

2 citations

Stamatina Fragkogianni, Leslie Weber, Tomi Lazarov, Yang Hu, Samantha Y. Hayashi +21 more

Splicing regulation of DNA repair via CCAR1

Molecular Cell(2024)10.1016/j.molcel.2024.06.012

N/A

0DataRank · unranked

0 citations

Omar Abdel-Wahab, Yuxi Ai

Reviewer #1 (Public review): A microglia clonal inflammatory disorder in Alzheimer’s Disease

(2024)10.7554/elife.96519.2.sa2

N/A

0DataRank · unranked

0 citations

Stamatina Fragkogianni, Leslie Weber, Tomi Lazarov, Yang Hu, Samantha Y Hayashi +21 more

Synergistic intragenic epigenetic deregulation by IDH2 and SRSF2 mutations causes mis-splicing of key transcriptional regulators

Science Advances(2026)10.1126/sciadv.adu8292

N/A

0DataRank · unranked

0 citations

Robert F. Stanley, Emmalee R. Adelman, Akihide Yoshimi, Adedamola A. Adele, Angelique Cruz +5 more

Mis-splicing-derived neoantigens and cognate TCRs in splicing factor mutant leukemias

Cell(2025)10.1016/j.cell.2025.03.047

N/A

0DataRank · unranked

38 citations

Edie I. Crosse, Emma De Neef, Iñaki Etxeberría, Erich Sabio, Eric Wang +31 more

A microglia clonal inflammatory disorder in Alzheimer’s disease

eLife(2025)10.7554/elife.96519.3

N/A

0DataRank · unranked

10 citations

Stamatina Fragkogianni, Leslie Weber, Tomi Lazarov, Yang Hu, Samantha Y. Hayashi +21 more

Phase Ib study of PRT543, an oral protein arginine methyltransferase 5 (PRMT5) inhibitor, in patients with advanced splicing factor-mutant myeloid malignancies

Leukemia(2025)10.1038/s41375-025-02515-8

N/A

0DataRank · unranked

13 citations

Xiaoli Mi, Bin Lü, Andrew Kuykendall, David A. Sallman, Manish R. Patel +16 more

RBM10 loss promotes metastases by aberrant splicing of cytoskeletal and extracellular matrix mRNAs

The Journal of Experimental Medicine(2025)10.1084/jem.20241029

N/A

0DataRank · unranked

9 citations

Anthony Glover, Brian R. Untch, Nickole Sigcha‐Coello, Bin Xu, Dina Vukel +15 more

Bone marrow and blood demonstrate distinct immune reconstitution patterns and correlations with relapse posttransplant

Blood Advances(2025)10.1182/bloodadvances.2024015626

N/A

0DataRank · unranked

4 citations

Jason Kuttiyara, Paola Vinci, Teng Fei, John Slingerland, Zoe Katsamakis +25 more

RAF-independent MEK mutations drive refractory histiocytic neoplasms but respond to ERK inhibition

Cancer Cell(2025)10.1016/j.ccell.2025.09.014

N/A

0DataRank · unranked

3 citations

Jean‐François Emile, T Fujino, Julien Haroche, Maxim I. Maron, Alexander M. Lewis +40 more

The Link between Modifiable Risk Factors and Myeloid Disorders—From Plate to Pathogenesis

Blood Cancer Discovery(2025)10.1158/2643-3230.bcd-25-0056

N/A

0DataRank · unranked

1 citations

Omar Abdel-Wahab, Urvi A. Shah, Joshua T. Weinreb

U2af1S34F and U2af1Q157R myeloid neoplasm-associated hotspot mutations induce distinct hematopoietic phenotypes in mice

Research Square(2025)10.21203/rs.3.rs-6377810/v1

N/A

0DataRank · unranked

0 citations

Sridhar Nonavinkere Srivatsan, Jin Shao, Dennis Fei, Mengou Zhu, Clauida Cabrera Pastrana +5 more

RNA Splicing as a Therapeutic Vulnerability in Therapy-Refractory Multiple Myeloma

Blood Cancer Discovery(2025)10.1158/2643-3230.bcd-25-0308

N/A

0DataRank · unranked

0 citations

Omar Abdel-Wahab, Maxim I. Maron

Phase I First-in-Human Dose Escalation Study of the oral Casein Kinase 1α and Cyclin Dependent Kinase 7/9 inhibitor BTX-A51 in advanced MDS and AML

Research Square(2024)10.21203/rs.3.rs-4954060/v1

N/A

0DataRank · unranked

0 citations

Wenbin Xiao, Gautam Borthakur, Le Xuan Truong Nguyen, Melissa Valerio, Avanthika Venkatachalam +11 more

Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia.

Journal of Clinical Investigation(2020)10.1172/jci129126

N/A

0DataRank · unranked

142 citations

Hongzhi Miao, Katarzyna Kempińska, Tao Wu, Trupta Purohit, Eungi Kim +30 more

DNA methylation disruption reshapes the hematopoietic differentiation landscape

Nature Genetics(2020)10.1038/s41588-020-0595-4

N/A

0DataRank · unranked

258 citations

Stanley Chun-Wei Lee, Asaf Poran, Ronan Chaligné, Federico Gaiti, Baptiste Gross +17 more

Mutations in the RNA Splicing Factor SF3B1 Promote Tumorigenesis through MYC Stabilization

Cancer Discovery(2020)10.1158/2159-8290.cd-19-1330

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0DataRank · unranked

123 citations

Akihide Yoshimi, Jiguang Wang, Hana Cho, Stanley Chun-Wei Lee, Michelle Ki +11 more

ZBTB1 Regulates Asparagine Synthesis and Leukemia Cell Response to L-Asparaginase

Cell Metabolism(2020)10.1016/j.cmet.2020.03.008

N/A

0DataRank · unranked

77 citations

Rohiverth Guarecuco, Leah Gates, Douglas Barrows, Maria C. Passarelli, Bryce W. Carey +15 more

Germ cell tumors and associated hematologic malignancies evolve from a common shared precursor

Journal of Clinical Investigation(2020)10.1172/jci139682

N/A

0DataRank · unranked

56 citations

Mark T.A. Donoghue, Caleb Ho, Kseniya Petrova‐Drus, Hikmat Al‐Ahmadie, Samuel A. Funt +22 more

The Contribution of MicroRNAs to the Inflammatory and Neoplastic Characteristics of Erdheim–Chester Disease

Cancers(2020)10.3390/cancers12113240

N/A

0DataRank · unranked

11 citations

Eli L. Diamond, Julien Haroche, Nir Pillar, Guy Shapira, Benjamin Durham +13 more

Rare and private spliceosomal gene mutations drive partial, complete, and dual phenocopies of hotspot alterations

Blood(2020)10.1182/blood.2019002894

N/A

0DataRank · unranked

16 citations

Jean‐Jacques Kiladjian, Bruno Cassinat, Aline Renneville, Justin Taylor, Jacob T. Polaski +4 more

Leveraging Systematic Functional Analysis to Benchmark an In Silico Framework Distinguishes Driver from Passenger MEK Mutants in Cancer

Cancer Research(2020)10.1158/0008-5472.can-20-0865

N/A

0DataRank · unranked

31 citations

Brooke E. Sylvester, Matthew T. Chang, Arijh Elzein, Jianjiong Gao, Weiwei Han +24 more

ABCA1 Exerts Tumor-Suppressor Function in Myeloproliferative Neoplasms

Cell Reports(2020)10.1016/j.celrep.2020.02.056

N/A

0DataRank · unranked

25 citations

Omar Abdel-Wahab, Julie Gall, Stoyan Ivanov, Rodolphe Guinamard, Sophie Sore +10 more

MAP-Kinase-Driven Hematopoietic Neoplasms: A Decade of Progress in the Molecular Age

Cold Spring Harbor Perspectives in Medicine(2020)10.1101/cshperspect.a034892

N/A

0DataRank · unranked

38 citations

Omar Abdel-Wahab, Benjamin H. Durham, Rikhia Chakraborty

Pharmacologic modulation of RNA splicing enhances anti-tumor immunity

Cell(2021)10.1016/j.cell.2021.05.038

N/A

0DataRank · unranked

284 citations

Emma De Neef, James D. Thomas, Erich Sabio, Benoı̂t Rousseau, Mathieu Gigoux +30 more

Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition

Molecular Cell(2021)10.1016/j.molcel.2021.04.015

N/A

0DataRank · unranked

173 citations

Olga Motorna, Leonie A. Cluse, Timothy M. Johanson, Hannah D. Coughlan, Ramya Raviram +37 more

Splicing factor mutations in hematologic malignancies

Blood(2021)10.1182/blood.2019004260

N/A

0DataRank · unranked

97 citations

Salima Benbarche, Omar Abdel-Wahab, Sisi Chen

Histiocytosis and the nervous system: from diagnosis to targeted therapies

Neuro-Oncology(2021)10.1093/neuonc/noab107

N/A

0DataRank · unranked

96 citations

Ahmed Idbaïh, Jean‐François Emile, Zahir Amoura, Omar Abdel-Wahab, Benjamin H. Durham +3 more

Coordinated missplicing of TMEM14C and ABCB7 causes ring sideroblast formation in SF3B1-mutant myelodysplastic syndrome

Blood(2021)10.1182/blood.2021012652

N/A

0DataRank · unranked

84 citations

Joseph Pangallo, Martina Sarchi, Janine O. Ilagan, Khrystyna North, Rochelle Bergantinos +11 more

Therapeutic Modulation of RNA Splicing in Malignant and Non-Malignant Disease

Trends in Molecular Medicine(2021)10.1016/j.molmed.2021.04.005

N/A

0DataRank · unranked

69 citations

Omar Abdel-Wahab, Ettaib El Marabti

U2af1 is required for survival and function of hematopoietic stem/progenitor cells

Leukemia(2021)10.1038/s41375-020-01116-x

N/A

0DataRank · unranked

41 citations

Yue Yang, Bao T. Le, Yifan Zhang, Omar Abdel-Wahab, Chongzhi Zang +2 more

Splicing-Mediated Antigen Escape from Immunotherapy for B-cell Malignancies

Blood Cancer Discovery(2021)10.1158/2643-3230.bcd-21-0200

N/A

0DataRank · unranked

6 citations

Omar Abdel-Wahab, Jessie Bourcier

mRNA Export as a Novel Cancer-Specific Dependency

Cancer Discovery(2021)10.1158/2159-8290.cd-21-0862

N/A

0DataRank · unranked

2 citations

Omar Abdel-Wahab, Eric Wang

Histiocytosis and the nervous system: from diagnosis to targeted therapies

HAL (Le Centre pour la Communication Scientifique Directe)(2021)10.1093/neuonc/noab107/6276475

N/A

0DataRank · unranked

1 citations

Idbaih, Ahmed, Jean‐François Emile, Zahir Amoura, Omar Abdel-Wahab, Benjamin H. Durham +3 more

Repeats Mimic Pathogen-Associated Patterns Across a Vast Evolutionary Landscape

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.04.467016

N/A

0DataRank · unranked

14 citations

Andrea Di Gioacchino, Alexander Solovyov, Sajid A. Marhon, Siyu Sun, Håvard T. Lindholm +13 more