Igor Vorobyov

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 27 papers. Top paper: “CHARMM general force field: A force field for drug‐like molecules compatible with the CHARMM all‐atom additive biological force fields”.

CHARMM general force field: A force field for drug‐like molecules compatible with the CHARMM all‐atom additive biological force fields

Journal of Computational Chemistry(2009)10.1002/jcc.21367

N/A

1.3DataRank · unranked

7386 citations

E. Hatcher, C. Acharya, S. Kundu, S. Zhong, J. Shim +16 more

Harnessing AlphaFold to reveal hERG channel conformational state secrets

eLife(2024)10.7554/elife.104901

N/A

0.406DataRank · unranked

9 citations

Pei‐Chi Yang, Vladimir Yarov‐Yarovoy, Colleen E. Clancy, Igor Vorobyov, Khoa Ngo

Elucidating molecular mechanisms of protoxin-II state-specific binding to the human NaV1.7 channel

The Journal of General Physiology(2023)10.1085/jgp.202313368

N/A

0.382DataRank · unranked

10 citations

Diego López Mateos, Yanxiao Han, Kyle C. Rouen, Surl-Hee Ahn, Heike Wulff +4 more

Structural modeling of hERG channel–drug interactions using Rosetta

Frontiers in Pharmacology(2023)10.3389/fphar.2023.1244166

N/A

0.299DataRank · unranked

5 citations

Kevin R. DeMarco, Kazuharu Furutani, Slava Bekker, Jon T. Sack, Heike Wulff +4 more

Harnessing AlphaFold to reveal hERG channel conformational state secrets

(2024)10.1101/2024.01.27.577468

N/A

0.182DataRank · unranked

2 citations

Pei‐Chi Yang, Vladimir Yarov‐Yarovoy, Colleen E. Clancy, Igor Vorobyov, Khoa Ngo

Molecular determinants of pro-arrhythmia proclivity of d- and l-sotalol via a multi-scale modeling pipeline

Journal of Molecular and Cellular Cardiology(2021)10.1016/j.yjmcc.2021.05.015

N/A

0DataRank · unranked

24 citations

Pei‐Chi Yang, Vikrant Singh, Kazuharu Furutani, John R.D. Dawson, Mao-Tsuen Jeng +10 more

Structural modeling of the hERG potassium channel and associated drug interactions

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.08.451699

N/A

0DataRank · unranked

1 citations

Aiyana M. Emigh, Kevin R. DeMarco, Kazuharu Furutani, Jon T. Sack, Colleen E. Clancy +3 more

Rearrangement of a unique Kv1.3 selectivity filter conformation upon binding of a drug

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2113536119

N/A

0DataRank · unranked

52 citations

Tofayel Ahmed, Shi Jian, Saumya Bajaj, Seow Theng Ong, Stephanie Shee Min Goay +6 more

Structural modeling of the hERG potassium channel and associated drug interactions

Frontiers in Pharmacology(2022)10.3389/fphar.2022.966463

N/A

0DataRank · unranked

23 citations

Aiyana M. Emigh, Kevin R. DeMarco, Kazuharu Furutani, Jon T. Sack, Colleen E. Clancy +3 more

Elucidation of a dynamic interplay between a beta-2 adrenergic receptor, its agonist, and stimulatory G protein

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2215916120

N/A

0DataRank · unranked

25 citations

John R.D. Dawson, Kevin R. DeMarco, Kyle C. Rouen, Slava Bekker, Vladimir Yarov‐Yarovoy +4 more

Toward Digital Twin Technology for Precision Pharmacology

JACC. Clinical electrophysiology(2023)10.1016/j.jacep.2023.10.024

N/A

0DataRank · unranked

21 citations

Mao-Tsuen Jeng, Vladimir Yarov‐Yarovoy, Luis F. Santana, Igor Vorobyov, Colleen E. Clancy +1 more

A multiscale predictive digital twin for neurocardiac modulation

The Journal of Physiology(2023)10.1113/jp284391

N/A

0DataRank · unranked

23 citations

Adam J. Rose, Kevin R. DeMarco, John R.D. Dawson, Yanxiao Han, Mao-Tsuen Jeng +7 more

A deep learning algorithm to translate and classify cardiac electrophysiology

eLife(2021)10.7554/elife.68335

N/A

0DataRank · unranked

30 citations

Pei‐Chi Yang, Divya C. Kernik, K. Sakamoto, Yasunari Kanda, Junko Kurokawa +3 more

Selectivity filter modalities and rapid inactivation of the hERG1 channel

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.1909196117

N/A

0DataRank · unranked

52 citations

Kevin R. DeMarco, Jiqing Guo, Henry J. Duff, Igor Vorobyov, Colleen E. Clancy +2 more

Elucidating Molecular Mechanisms of Protoxin-2 State-specific Binding to the Human Na V 1.7 Channel

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.27.530360

N/A

0DataRank · unranked

1 citations

Diego López Mateos, Yanxiao Han, Kyle C. Rouen, Surl-Hee Ahn, Heike Wulff +4 more

Modeling Stereospecific Drug Interactions with Beta-Adrenergic Receptors

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.01.560334

N/A

0DataRank · unranked

1 citations

Kevin R. DeMarco, Yanxiao Han, Slava Bekker, Colleen E. Clancy, Vladimir Yarov‐Yarovoy +2 more

The Membrane Dipole Potential and the Roles of Interfacial Water and Lipid Hydrocarbon Chains

The Journal of Physical Chemistry B(2024)10.1021/acs.jpcb.4c04469

N/A

0DataRank · unranked

14 citations

Igor Vorobyov, Ronald J. Clarke, Toby W. Allen, Bogdan Lev

Atomistic mechanisms of the regulation of small-conductance Ca 2+ -activated K + channel (SK2) by PIP2

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2318900121

N/A

0DataRank · unranked

11 citations

Yang Zheng, Woori Choi, Khoa Ngo, Pauline Trinh, Lu Ren +14 more

A Computational Pipeline to Predict Cardiotoxicity

Circulation Research(2020)10.1161/circresaha.119.316404

N/A

0DataRank · unranked

84 citations

Kevin R. DeMarco, Parya Aghasafari, Mao-Tsuen Jeng, John R.D. Dawson, Slava Bekker +5 more

Reviewer #1 (Public review): Harnessing AlphaFold to reveal hERG channel conformational state secrets

(2024)10.7554/elife.104901.1.sa2

N/A

0DataRank · unranked

0 citations

Pei-Chi Yang, Vladimir Yarov-Yarovoy, Colleen E Clancy, Igor Vorobyov, Khoa Ngo

Author response: Harnessing AlphaFold to reveal hERG channel conformational state secrets

(2024)10.7554/elife.104901.1.sa4

N/A

0DataRank · unranked

0 citations

Pei‐Chi Yang, Vladimir Yarov‐Yarovoy, Colleen E. Clancy, Igor Vorobyov, Khoa Ngo

Ligand Dissociation Pathways from Membrane Receptors Revealed by Weighted Ensemble Simulations

The Journal of Physical Chemistry B(2025)10.1021/acs.jpcb.5c04545

N/A

0DataRank · unranked

3 citations

Kyle C. Rouen, Vladimir Yarov‐Yarovoy, Colleen E. Clancy, Yang K. Xiang, Igor Vorobyov +2 more

Molecular simulations reveal intricate coupling between agonist-bound β-adrenergic receptors and G protein

iScience(2025)10.1016/j.isci.2024.111741

N/A

0DataRank · unranked

5 citations

John R.D. Dawson, Kevin R. DeMarco, Kyle C. Rouen, Khoa Ngo, Slava Bekker +6 more

6,7-Dichloro-1H-indole-2,3-dione-3-oxime functions as a superagonist for the intermediate-conductance Ca2+-activated K+ channel KCa3.1

Molecular Pharmacology(2025)10.1016/j.molpha.2025.100018

N/A

0DataRank · unranked

3 citations

Kyle C. Rouen, Connor Dietrich, Heesung Shim, Miao Zhang, Igor Vorobyov +2 more

Prediction of TdP Arrhythmia Risk Through Molecular Simulations of Conformation-specific Drug Interactions with the hERG K + , Na V 1.5, and Ca V 1.2 Channels

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.25.678690

N/A

0DataRank · unranked

1 citations

Kush Narang, Yanxiao Han, David Wang, Ensley Jang, Sophia Brunkow +4 more

Molecular Dynamics Simulations Based on Polarizable Models Show that Ion Permeation Interconverts between Different Mechanisms as a Function of Membrane Thickness

The Journal of Physical Chemistry B(2021)10.1021/acs.jpcb.0c08613

N/A

0DataRank · unranked

25 citations

Igor Vorobyov, Benoı̂t Roux, Toby W. Allen, Peiran Chen

Harnessing AlphaFold to reveal hERG channel conformational state secrets

eLife(2025)10.7554/elife.104901.3

N/A

0DataRank · unranked

0 citations

Pei‐Chi Yang, Vladimir Yarov‐Yarovoy, Colleen E. Clancy, Igor Vorobyov, Khoa Ngo