Mélanie Ott

Also affiliated with University of California, San Francisco, University of California System, Chan Zuckerberg Initiative (United States), University of San Francisco

MedicineImmunology and MicrobiologyBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 7%percentile

0.104Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Data supporting 'De novo-designed minibinders expand the synthetic biology sensing repertoire'

Zenodo (CERN European Organization for Nuclear Research)(2024)10.5281/zenodo.10480660

Top 78%

0.104DataRank

Top 78%1 citations

Sarah S. Soliman, Matthew S. Kim, Irene P. Chen, Mélanie Ott, Hana El‐Samad +1 more

Papers

Driven by 109 papers — median percentile 11. Top paper: “A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing”.

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.22.002386

N/A

14.3DataRank · unranked

456 citations

Gwendolyn M. Jang, Mehdi Bouhaddou, Jiewei Xu, Kirsten Obernier, Matthew J. O’Meara +95 more

Amplification-free detection of SARS-CoV-2 with CRISPR-Cas13a and mobile phone microscopy

Cell(2020)10.1016/j.cell.2020.12.001

N/A

13.6DataRank · unranked

1034 citations

Sungmin Son, María Díaz de León Derby, Gavin J. Knott, Carley N Gray, Michael V. D’Ambrosio +27 more

The Global Phosphorylation Landscape of SARS-CoV-2 Infection

Cell(2020)10.1016/j.cell.2020.06.034

N/A

10.3DataRank · unranked

1152 citations

Danish Memon, Bjoern Meyer, Kris M. White, Veronica V. Rezelj, Miguel Correa Marrero +73 more

An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike

Science(2020)10.1126/science.abe3255

N/A

9.7DataRank · unranked

468 citations

Bryan Faust, Reuben A. Saunders, Smriti Sangwan, Veronica V. Rezelj, Nick Hoppe +68 more

Neutralizing immunity in vaccine breakthrough infections from the SARS-CoV-2 Omicron and Delta variants

Cell(2022)10.1016/j.cell.2022.03.019

N/A

9.1DataRank · unranked

176 citations

Abdullah M. Syed, Mary Kate Morris, Noah Brazer, Prachi Saldhi, Miguel Garcia-Knight +19 more

Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men

Cell stem cell(2020)10.1016/j.stem.2020.11.009

N/A

7.3DataRank · unranked

251 citations

Homa Majd, Mikayla N Richter, Zaniar Ghazizadeh, Seyedeh M. Zekavat, Albertas Navickas +19 more

Tropism of SARS-CoV-2 for human cortical astrocytes

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2122236119

N/A

3.6DataRank · unranked

163 citations

Tanzila Mukhtar, Ugomma C. Eze, Camille R. Simoneau, Jayden Ross, Neelroop Parikshak +23 more

Fibrin drives thromboinflammation and neuropathology in COVID-19

Nature(2024)10.1038/s41586-024-07873-4

N/A

2.0DataRank · unranked

99 citations

Zhaoqi Yan, Mauricio Montaño, Elif G. Sözmen, Karuna Dixit, Rahul K. Suryawanshi +39 more

An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.08.238469

N/A

2.0DataRank · unranked

49 citations

Bryan Faust, Reuben A. Saunders, Smriti Sangwan, Veronica V. Rezelj, Nick Hoppe +51 more

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

Nature(2020)10.1038/s41586-020-2286-9

N/A

1.3DataRank · unranked

4829 citations

Gwendolyn M. Jang, Mehdi Bouhaddou, Jiewei Xu, Kirsten Obernier, Kris M. White +95 more

Viral E protein neutralizes BET protein-mediated post-entry antagonism of SARS-CoV-2

Cell Reports(2022)10.1016/j.celrep.2022.111088

N/A

1.1DataRank · unranked

25 citations

James E. Longbotham, Sarah McMahon, Rahul K. Suryawanshi, Mir M. Khalid, Taha Y. Taha +17 more

SARS-CoV-2 infection of human iPSC–derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19

Science Translational Medicine(2021)10.1126/scitranslmed.abf7872

N/A

0.835DataRank · unranked

260 citations

Michael S. Kang, Sarah J. Rockwood, Camille R. Simoneau, David Joy, Ana C. Silva +13 more

Omicron mutations enhance infectivity and reduce antibody neutralization of SARS-CoV-2 virus-like particles

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2200592119

N/A

0.802DataRank · unranked

209 citations

Alison Ciling, Taha Y. Taha, Irene P. Chen, Mir M. Khalid, Bharath Sreekumar +16 more

Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo

Cell stem cell(2020)10.1016/j.stem.2020.07.020

N/A

0.757DataRank · unranked

154 citations

Andrew Ha, Wim de Lau, Kanako Yuki, António J. M. Santos, Changjiang You +28 more

SARS-CoV-2 infection of human iPSC-derived cardiac cells predicts novel cytopathic features in hearts of COVID-19 patients

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.25.265561

N/A

0.668DataRank · unranked

85 citations

Michael S. Kang, Sarah J. Rockwood, Camille R. Simoneau, David Joy, Gokul N. Ramadoss +9 more

SARS-CoV-2 evolution balances conflicting roles of N protein phosphorylation

PLoS Pathogens(2024)10.1371/journal.ppat.1012741

N/A

0.655DataRank · unranked

24 citations

Alison Ciling, Irene P. Chen, Christopher R. Carlson, Armin N. Adly, Hannah S. Martin +11 more

Structure-function analysis of enterovirus protease 2A in complex with its essential host factor SETD3

Nature Communications(2022)10.1038/s41467-022-32758-3

N/A

0.612DataRank · unranked

9 citations

Ursula Schulze‐Gahmen, Manon Eckhardt, Gwendolyn M. Jang, Jiewei Xu, Ernst H. Pulido +9 more

Transcriptomics-based drug repositioning pipeline identifies therapeutic candidates for COVID-19

Scientific Reports(2021)10.1038/s41598-021-91625-1

N/A

0.601DataRank · unranked

54 citations

Gaia Andreoletti, Tomiko Oskotsky, Albert Vallejo-Gracia, Romel Rosales, Katharine Yu +10 more

Structure-Based Discovery of Inhibitors of the SARS-CoV-2 Nsp14 N7-Methyltransferase

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.2c02120

N/A

0.587DataRank · unranked

49 citations

Fengling Li, Elissa A. Fink, Irene Chau, Alice Shi Ming Li, Annia Rodríguez‐Hernández +18 more

The lysine methyltransferase SMYD5 amplifies HIV-1 transcription and is post-transcriptionally upregulated by Tat and USP11

Cell Reports(2023)10.1016/j.celrep.2023.112234

N/A

0.457DataRank · unranked

20 citations

Victor L. Lam, Martina Schnölzer, Mélanie Ott, Daniela Boehm

SARS-CoV-2 protein ORF8 limits expression levels of Spike antigen and facilitates immune evasion of infected host cells

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.104955

N/A

0.449DataRank · unranked

19 citations

Yong‐ho Lee, Mir M. Khalid, Irene P. Chen, Yini Zhang, Mélanie Ott +2 more

Transcriptomics-based drug repositioning pipeline identifies therapeutic candidates for COVID-19

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.23.352666

N/A

0.426DataRank · unranked

7 citations

Gaia Andreoletti, Tomiko Oskotsky, Albert Vallejo-Gracia, Romel Rosales, Katharine Yu +10 more

SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.04.474979

N/A

0.425DataRank · unranked

16 citations

Irene P. Chen, Albert Vallejo-Gracia, Ik-Jung Kim, Olga Bielska, Victor L. Lam +9 more

Post-acute immunological and behavioral sequelae in mice after Omicron infection

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.05.543758

N/A

0.360DataRank · unranked

10 citations

Rahul K. Suryawanshi, Stephanie R. Miller, Katie K. Ly, Reuben Thomas, Natalie Elphick +13 more

CRISPR-Cas9 screen of E3 ubiquitin ligases identifies TRAF2 and UHRF1 as regulators of HIV latency in primary human T cells

mBio(2024)10.1128/mbio.02222-23

N/A

0.351DataRank · unranked

8 citations

Paige Haas, Vigneshwari Easwar Kumar, Joseph Hiatt, Kelsey M. Haas, Mehdi Bouhaddou +16 more

Previous exposure to Spike-providing parental strains confers neutralizing immunity to XBB lineage and other SARS-CoV-2 recombinants in the context of vaccination

Emerging Microbes & Infections(2023)10.1080/22221751.2023.2270071

N/A

0.340DataRank · unranked

5 citations

Taha Y. Taha, Maria McCavitt-Malvido, Inês Silva, Mir M. Khalid, Abdullah M. Syed +28 more

NF-κB inhibitor alpha has a cross-variant role during SARS-CoV-2 infection in ACE2-overexpressing human airway organoids

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.02.502100

N/A

0.282DataRank · unranked

3 citations

Peiyi Chen, Galen Xing, Mir M. Khalid, Nathan L. Meyers, Jennifer M. Hayashi +18 more

Transcriptomics-based drug repositioning pipeline identifies therapeutic candidates for COVID-19

Research Square(2021)10.21203/rs.3.rs-333578/v1

N/A

0.241DataRank · unranked

4 citations

Gaia Andreoletti, Tomiko Oskotsky, Albert Vallejo-Gracia, Romel Rosales, Katharine Yu +10 more

Structure-function analysis of enterovirus protease 2A in complex with its essential host factor SETD3

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.22.497068

N/A

0.165DataRank · unranked

2 citations

Ursula Schulze‐Gahmen, Manon Eckhardt, Gwendolyn M. Jang, Jiewei Xu, Ernst H. Pulido +7 more

The Mac1 ADP-ribosylhydrolase is a therapeutic target for SARS-CoV-2

eLife(2025)10.7554/elife.103484.3

N/A

0.104DataRank · unranked

1 citations

Priyadarshini Jaishankar, G.J. Correy, Moira Rachman, Patrick C. O’Leary, Taha Y. Taha +26 more

Data supporting 'De novo-designed minibinders expand the synthetic biology sensing repertoire'

Zenodo (CERN European Organization for Nuclear Research)(2024)10.5281/zenodo.10480660

Top 78%

0.104DataRank

Top 78%1 citations

Sarah S. Soliman, Matthew S. Kim, Irene P. Chen, Mélanie Ott, Hana El‐Samad +1 more

Evaluating a New Class of AKT/mTOR Activators for HIV Latency-Reversing Activity Ex Vivo and In Vivo

Journal of Virology(2021)10.1128/jvi.02393-20

N/A

0DataRank · unranked

25 citations

Roland Schwarzer, William Brantley, Benjamin Varco-Merth, Hannah S. Sperber, Philip A. Hull +27 more

Novel RT-ddPCR assays for simultaneous quantification of multiple noncoding and coding regions of SARS-CoV-2 RNA

Journal of Virological Methods(2021)10.1016/j.jviromet.2021.114115

N/A

0DataRank · unranked

19 citations

Nitasha Kumar, Albert Vallejo-Gracia, G. Renuka Kumar, Chuanyi M. Lu, Mélanie Ott +3 more

Transmission, infectivity, and antibody neutralization of an emerging SARS-CoV-2 variant in California carrying a L452R spike protein mutation

medRxiv(2021)10.1101/2021.03.07.21252647

N/A

0DataRank · unranked

247 citations

Miguel Garcia-Knight, Mir M. Khalid, Venice Servellita, Candace Wang, Mary Kate Morris +41 more

Omicron mutations enhance infectivity and reduce antibody neutralization of SARS-CoV-2 virus-like particles

medRxiv(2021)10.1101/2021.12.20.21268048

N/A

0DataRank · unranked

75 citations

Alison Ciling, Mir M. Khalid, Bharath Sreekumar, Peiyi Chen, G. Renuka Kumar +15 more

Tropism of SARS-CoV-2 for Developing Human Cortical Astrocytes

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.17.427024

N/A

0DataRank · unranked

51 citations

Tanzila Mukhtar, Ugomma C. Eze, Camille R. Simoneau, Yonatan Perez, Mohammed A. Mostajo-Radji +9 more

Accelerated RNA detection using tandem CRISPR nucleases

medRxiv(2021)10.1101/2021.03.19.21253328

N/A

0DataRank · unranked

21 citations

Gavin J. Knott, Dylan C. J. Smock, John J. Desmarais, Sungmin Son, Abdul Bhuiya +29 more

Sensitive and multiplexed RNA detection with Cas13 droplets and kinetic barcoding

medRxiv(2021)10.1101/2021.08.02.21261509

N/A

0DataRank · unranked

15 citations

Amy Lyden, Jeffrey Shu, Stephanie I. Stephens, Parinaz Fozouni, Gavin J. Knott +9 more

Publisher Correction: Accelerated RNA detection using tandem CRISPR nucleases

Nature Chemical Biology(2021)10.1038/s41589-021-00882-8

N/A

0DataRank · unranked

8 citations

Gavin J. Knott, Dylan C. J. Smock, John J. Desmarais, Sungmin Son, Abdul Bhuiya +43 more

EDITORIAL: Hydration for Clean Air Today

Molecular Frontiers Journal(2021)10.1142/s252973252101001x

N/A

0DataRank · unranked

8 citations

Bengt Nordén, Lorie Karnath, Omar M. Yaghi, Chad J. Roy, Donald C. Johanson +6 more

Viral E Protein Neutralizes BET Protein-Mediated Post-Entry Antagonism of SARS-CoV-2

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.14.468537

N/A

0DataRank · unranked

4 citations

James E. Longbotham, Sarah McMahon, Rahul K. Suryawanshi, Jared Carlson-Stevermer, Meghna Gupta +15 more

Hepatitis C Virus Infects and Perturbs Liver Stem Cells

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.26.465357

N/A

0DataRank · unranked

1 citations

Tal Ashuach, Danielle E. Lyons, Camille R. Simoneau, Ann L. Erickson, Mehdi Bouhaddou +15 more

Novel RT-ddPCR Assays for determining the transcriptional profile of SARS-CoV-2

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.12.425991

N/A

0DataRank · unranked

0 citations

Nitasha Kumar, Albert Vallejo-Gracia, G. Renuka Kumar, Chuanyi M. Lu, Mélanie Ott +3 more

Snapshots: Chromatin control of viral infection

UNC Libraries(2021)10.17615/y0kx-xm67

N/A

0DataRank · unranked

0 citations

Jae U. Jung, Michael Nevels, Amelia Nieto, Kevin V. Morris, Alison A. McBride +6 more

Limited cross-variant immunity from SARS-CoV-2 Omicron without vaccination

Nature(2022)10.1038/s41586-022-04865-0

N/A

0DataRank · unranked

214 citations

Irene P. Chen, Tongcui Ma, Abdullah M. Syed, Noah Brazer, Prachi Saldhi +38 more

International AIDS Society global scientific strategy: towards an HIV cure 2016

UNC Libraries(2020)10.17615/7q2b-ex16

N/A

0DataRank · unranked

0 citations

Éric A Cohen, Guido Silvestri, Laurindo Garcia, Janet D. Siliciano, Jeffrey Taylor +50 more

Snapshots: Chromatin control of viral infection

UNC Libraries(2020)10.17615/va0g-q033

N/A

0DataRank · unranked

0 citations

Alison A. McBride, Jae U. Jung, Amelia Nieto, David M. Knipe, Kevin V. Morris +6 more

Zika Virus Infection Prevents Host mRNA Nuclear Export by Disrupting UPF1 Function

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.03.410837

N/A

0DataRank · unranked

3 citations

Ryan A. Flynn, Mir M. Khalid, Krystal A. Fontaine, Tom Nguyen, G. Renuka Kumar +12 more

Accelerating PERx reaction enables covalent nanobodies for potent neutralization of SARS-CoV-2 and variants

Chem(2022)10.1016/j.chempr.2022.07.012

N/A

0DataRank · unranked

64 citations

Shanshan Li, Takako Tabata, Nanxi Wang, Li Cao, G. Renuka Kumar +5 more

SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein

PLoS Pathogens(2022)10.1371/journal.ppat.1010811

N/A

0DataRank · unranked

33 citations

Irene P. Chen, Albert Vallejo-Gracia, Ik-Jung Kim, Olga Bielska, Victor L. Lam +11 more

Screening a library of FDA-approved and bioactive compounds for antiviral activity against SARS-CoV-2

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.30.424862

N/A

0DataRank · unranked

4 citations

Erik Van Dis, Eddie Wehri, Lívia H. Yamashiro, Xammy Nguyenla, Claire Dugast‐Darzacq +18 more

Neutralizing antibody activity against SARS-CoV-2 variants in gestational age–matched mother-infant dyads after infection or vaccination

JCI Insight(2022)10.1172/jci.insight.157354

N/A

0DataRank · unranked

23 citations

Lin Li, Mary Prahl, Arianna G. Cassidy, Nida Özarslan, Yarden Golan +30 more

Neutralizing Immunity Induced Against the Omicron BA.1 and BA.2 Variants in Vaccine Breakthrough Infections

The Journal of Infectious Diseases(2022)10.1093/infdis/jiac384

N/A

0DataRank · unranked

11 citations

Mary Kate Morris, Venice Servellita, Khamal Anglin, Prachi Saldhi, Miguel Garcia-Knight +16 more

FOXO1 promotes HIV Latency by suppressing ER stress in T cells

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.23.058123

N/A

0DataRank · unranked

5 citations

Irene P. Chen, Rosalba Perrone, Emilie Besnard, Daniela Boehm, Emilie Battivelli +12 more

A Single-Component Luminescent Biosensor for the SARS-CoV-2 Spike Protein

Journal of the American Chemical Society(2022)10.1021/jacs.2c04192

N/A

0DataRank · unranked

15 citations

Heegwang Roh, Rahul Suryawanshi, G. Renuka Kumar, John E. Pak, Mélanie Ott +2 more

Catching BETs by viruses

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms(2022)10.1016/j.bbagrm.2022.194859

N/A

0DataRank · unranked

4 citations

Irene P. Chen, Siddappa N. Byrareddy, Danica Galonić Fujimori, Mélanie Ott, Tatiana G. Kutateladze +1 more

Taking cues from convalescence to improve vaccines against hepatitis C virus

Journal of Clinical Investigation(2022)10.1172/jci161819

N/A

0DataRank · unranked

1 citations

Taha Y. Taha, Mélanie Ott, Bharath Sreekumar

Limited Cross-Variant Immunity after Infection with the SARS-CoV-2 Omicron Variant Without Vaccination

medRxiv(2022)10.1101/2022.01.13.22269243

N/A

0DataRank · unranked

35 citations

Irene P. Chen, Tongcui Ma, Abdullah M. Syed, Noah Brazer, Prachi Saldhi +33 more

Neutralizing immunity in vaccine breakthrough infections from the SARS-CoV-2 Omicron and Delta variants

medRxiv(2022)10.1101/2022.01.25.22269794

N/A

0DataRank · unranked

23 citations

Abdullah M. Syed, Noah Brazer, Prachi Saldhi, Miguel Garcia-Knight, Bharath Sreekumar +16 more

Functional genomic screens identify human host factors for SARS-CoV-2 and common cold coronaviruses

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.24.312298

N/A

0DataRank · unranked

33 citations

Camille R. Simoneau, Jessie Kulsuptrakul, Mehdi Bouhaddou, Katherine Travisano, Jennifer M. Hayashi +7 more

Mild SARS-CoV-2 infection results in long-lasting microbiota instability

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.12.07.519508

N/A

0DataRank · unranked

11 citations

Rahul Suryawanshi, Preston Tasoff, Maria McCavitt-Malvido, G. Renuka Kumar, Victoria Murray +11 more

Immediate myeloid depot for SARS-CoV-2 in the human lung

Research Square(2022)10.21203/rs.3.rs-1639631/v1

N/A

0DataRank · unranked

5 citations

Ran You, Arjun A. Rao, Ryan T. Davis, Lauren Rodriguez, Camille R. Simoneau +15 more

Accelerating PERx Reaction Enables Covalent Nanobodies for Potent Neutralization of SARS-Cov-2 and Variants

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.11.483867

N/A

0DataRank · unranked

3 citations

Shanshan Li, Takako Tabata, Nanxi Wang, G. Renuka Kumar, Jun Liu +3 more

Immediate myeloid depot for SARS-CoV-2 in the human lung

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.04.28.489942

N/A

0DataRank · unranked

3 citations

Ran You, Arjun A. Rao, Ryan T. Davis, Lauren Rodriguez, Camille R. Simoneau +15 more

Rapid assembly of SARS-CoV-2 genomes reveals attenuation of the Omicron BA.1 variant through NSP6

Nature Communications(2023)10.1038/s41467-023-37787-0

N/A

0DataRank · unranked

71 citations

Irene P. Chen, Jennifer M. Hayashi, Takako Tabata, Keith Walcott, Gabriella R. Kimmerly +14 more

Direct detection of SARS-CoV-2 using CRISPR-Cas13a and a mobile phone

medRxiv(2020)10.1101/2020.09.28.20201947

N/A

0DataRank · unranked

59 citations

Sungmin Son, María Díaz de León Derby, Gavin J. Knott, Carley N Gray, Michael V. D’Ambrosio +23 more

Mild SARS-CoV-2 infection results in long-lasting microbiota instability

mBio(2023)10.1128/mbio.00889-23

N/A

0DataRank · unranked

37 citations

Rahul K. Suryawanshi, Preston Tasoff, Maria McCavitt-Malvido, Renuka Kumar, Victoria Murray +11 more

A single inactivating amino acid change in the SARS-CoV-2 NSP3 Mac1 domain attenuates viral replication in vivo

PLoS Pathogens(2023)10.1371/journal.ppat.1011614

N/A

0DataRank · unranked

37 citations

Rahul K. Suryawanshi, Irene P. Chen, G.J. Correy, Maria McCavitt-Malvido, Patrick C. O’Leary +12 more

Modeling Multi-organ Infection by SARS-CoV-2 Using Stem Cell Technology

Cell stem cell(2020)10.1016/j.stem.2020.11.012

N/A

0DataRank · unranked

36 citations

Mélanie Ott, Camille R. Simoneau

An ‘Arms Race’ between the Nonsense-mediated mRNA Decay Pathway and Viral Infections

Seminars in Cell and Developmental Biology(2020)10.1016/j.semcdb.2020.05.018

N/A

0DataRank · unranked

37 citations

Mélanie Ott, Kristoffer E. Leon

HIV-1 Remission: Accelerating the Path to Permanent HIV-1 Silencing

Viruses(2023)10.3390/v15112171

N/A

0DataRank · unranked

16 citations

Priti Kumar, Nadia R. Roan, Patricia Defechereux, Cédric Feschotte, Ulrike C. Lange +18 more

SARS-CoV-2 infection of airway organoids reveals conserved use of Tetraspanin-8 by Ancestral, Delta, and Omicron variants

Stem Cell Reports(2023)10.1016/j.stemcr.2023.01.011

N/A

0DataRank · unranked

14 citations

Samantha Little, Kayla Kulhanek, Mélia Magnen, Kriti Bahl, Oghenekevwe M. Gbenedio +37 more

A covalent inhibitor targeting the papain-like protease from SARS-CoV-2 inhibits viral replication

RSC Advances(2023)10.1039/d3ra00426k

N/A

0DataRank · unranked

8 citations

Albert Vallejo Gracia, Joachim Justad Røise, Lydia Boike, Kristoffer E. Leon, Ursula Schulze‐Gahmen +13 more

Mercapto-pyrimidines are reversible covalent inhibitors of the papain-like protease (PLpro) and inhibit SARS-CoV-2 (SCoV-2) replication

RSC Advances(2023)10.1039/d3ra01915b

N/A

0DataRank · unranked

7 citations

Eddie Wehri, Rahul K. Suryawanshi, Elizabeth A. King, Kundansingh Pardeshi, Kamyar Behrouzi +9 more

Comprehensive synergy mapping links a BAF- and NSL-containing “supercomplex” to the transcriptional silencing of HIV-1

Cell Reports(2023)10.1016/j.celrep.2023.113055

N/A

0DataRank · unranked

6 citations

Steven G. Deeks, Mélanie Ott, Warner C. Greene, Zichong Li

Nuclear accumulation of host transcripts during Zika Virus Infection

PLoS Pathogens(2023)10.1371/journal.ppat.1011070

N/A

0DataRank · unranked

6 citations

Mir M. Khalid, Ryan A. Flynn, Krystal A. Fontaine, Thông Nguyen, G. Renuka Kumar +12 more

3D human tissue models and microphysiological systems for HIV and related comorbidities

Trends in biotechnology(2023)10.1016/j.tibtech.2023.10.008

N/A

0DataRank · unranked

6 citations

Amy Palin, Tania Lombo, Robert N. Mahon, Betty Poon, Da-Yu Wu +29 more

A flow cytometry-based assay to investigate HIV-1 expression in SMYD5 shRNA containing primary CD4+ T cells

STAR Protocols(2023)10.1016/j.xpro.2023.102694

N/A

0DataRank · unranked

1 citations

Mélanie Ott, Daniela Boehm

A combinatorial view of old and new RNA polymerase II modifications

Transcription(2020)10.1080/21541264.2020.1762468

N/A

0DataRank · unranked

22 citations

Sarah McMahon, Mélanie Ott, Danielle E. Lyons

Rapid assembly of SARS-CoV-2 genomes reveals attenuation of the Omicron BA.1 variant through NSP6

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.31.525914

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5 citations

Irene P. Chen, Jennifer M. Hayashi, Takako Tabata, Keith Walcott, Gabriella R. Kimmerly +14 more

Assembly reactions of SARS-CoV-2 nucleocapsid protein with nucleic acid

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.22.568361

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5 citations

Abdullah M. Syed, Mir M. Khalid, Ai Nguyen, Alison Ciling, Di Wu +8 more

Colloidal aggregation confounds cell-based Covid-19 antiviral screens

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.27.564435

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4 citations

Lauren N. Hall, Mir M. Khalid, Mélanie Ott, Brian K. Shoichet, Isabella Glenn

A single inactivating amino acid change in the SARS-CoV-2 NSP3 Mac1 domain attenuates viral replication and pathogenesis in vivo

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.18.537104

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3 citations

Rahul K. Suryawanshi, Irene P. Chen, G.J. Correy, Patrick C. O’Leary, Manasi P. Jogalekar +10 more

Structure-based discovery of inhibitors of the SARS-CoV-2 Nsp14 N7 -methyltransferase

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.12.523677

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2 citations

Fengling Li, Elissa A. Fink, Irene Chau, Alice Li, Annia Rodríguez‐Hernández +18 more

Protocol for an in vitro assay to study HIV-1 Tat methylation

STAR Protocols(2023)10.1016/j.xpro.2023.102687

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0 citations

Katrin Kaehlcke, Martina Schnoelzer, Mélanie Ott, Daniela Boehm

Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages

Nature Metabolism(2020)10.1038/s42255-020-00305-3

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0DataRank · unranked

413 citations

Abhijit Kale, Rosalba Perrone, José A López-Domínguez, Angela Oliveira Pisco, Herbert G. Kasler +26 more

Assembly of SARS-CoV-2 nucleocapsid protein with nucleic acid

Nucleic Acids Research(2024)10.1093/nar/gkae256

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44 citations

Abdullah M. Syed, Mir M. Khalid, Ai Nguyen, Alison Ciling, Di Wu +8 more

Genetic Screens Identify Host Factors for SARS-CoV-2 and Common Cold Coronaviruses

Cell(2020)10.1016/j.cell.2020.12.004

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0DataRank · unranked

460 citations

Camille R. Simoneau, Jessie Kulsuptrakul, Mehdi Bouhaddou, Katherine Travisano, Jennifer M. Hayashi +15 more

Colloidal Aggregation Confounds Cell-Based Covid-19 Antiviral Screens

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c00597

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0DataRank · unranked

18 citations

Lauren N. Hall, Mir M. Khalid, Mélanie Ott, Brian K. Shoichet, Isabella Glenn

NF-κB inhibitor alpha controls SARS-CoV-2 infection in ACE2-overexpressing human airway organoids

Scientific Reports(2024)10.1038/s41598-024-66003-2

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14 citations

Peiyi Chen, Galen Xing, Jennifer M. Hayashi, Irene P. Chen, Mir M. Khalid +21 more

Immediate myeloid depot for SARS-CoV-2 in the human lung

Science Advances(2024)10.1126/sciadv.adm8836

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12 citations

Ran You, Arjun A. Rao, Ryan T. Davis, Lauren Rodriguez, O Bernard +20 more

SIRT1 is downregulated by autophagy in senescence and ageing

Nature Cell Biology(2020)10.1038/s41556-020-00579-5

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0DataRank · unranked

465 citations

Lu Wang, Parinaz Fozouni, Gry Evjen, Vemika Chandra, Jing Jiang +13 more

Neutralizing and binding antibody responses to SARS-CoV-2 with hybrid immunity in pregnancy

npj Vaccines(2024)10.1038/s41541-024-00948-3

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0DataRank · unranked

4 citations

Yusuke Matsui, Mary Prahl, Arianna G. Cassidy, Yarden Golan, Unurzul Jigmeddagva +20 more

Regulation of virion production by the ORF8 signal peptide across SARS-CoV-2 variants

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.05.583578

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8 citations

Irene P. Chen, Frank S Soveg, Taha Y. Taha, Takako Tabata, Rahul Suryawanshi +16 more

Torsional Twist of the SARS-CoV and SARS-CoV-2 SUD-N and SUD-M domains

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.08.13.607777

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2 citations

G. Minasov, J.S. Brunzelle, Taha Y. Taha, Sofia Lemak, Shaohui Yin +9 more

De novo -designed minibinders expand the synthetic biology sensing repertoire

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.12.575267

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0DataRank · unranked

1 citations

Sarah S. Soliman, Matthew S. Kim, Devan H Shah, Irene P. Chen, Mélanie Ott +3 more

De novo-designed minibinders expand the synthetic biology sensing repertoire

eLife(2024)10.7554/elife.96154.1

N/A

0DataRank · unranked

1 citations

Sarah S. Soliman, Matthew S. Kim, Irene P. Chen, Mélanie Ott, Hana El‐Samad +1 more

Data supporting 'De novo-designed minibinders expand the synthetic biology sensing repertoire'

Zenodo (CERN European Organization for Nuclear Research)(2024)10.5281/zenodo.10480659

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Sarah S. Soliman, Shah, Devan, Matthew S. Kim, Irene P. Chen, Mélanie Ott +3 more

A non-spike nucleocapsid R204P mutation in SARS-CoV-2 Omicron XEC enhances inflammation and pathogenicity

Nature Communications(2025)10.1038/s41467-025-67455-4

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0DataRank · unranked

1 citations

Masumi Tsuda, Sayaka Deguchi, Jumpei Ito, Taha Y. Taha, Hesham Nasser +71 more

The Mac1 ADP-ribosylhydrolase is a therapeutic target for SARS-CoV-2

eLife(2025)10.7554/elife.103484

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0DataRank · unranked

7 citations

Priyadarshini Jaishankar, G.J. Correy, Moira Rachman, Patrick C. O’Leary, Taha Y. Taha +26 more

Discovery of AVI-6451, a Potent and Selective Inhibitor of the SARS-CoV-2 ADP-Ribosylhydrolase Mac1 with Oral Efficacy in vivo

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.11.681833

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3 citations

G.J. Correy, Yusuke Matsui, Takaya Togo, Moira Rachman, Maisie GV Stevens +14 more

Programmable kinetic barcoding for multiplexed RNA detection with Cas13a

medRxiv(2025)10.1101/2025.07.03.25328829

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0DataRank · unranked

0 citations

Amy Lyden, Carlos Ng Pitti, Andres Dextre, Jeffrey Shu, Stephanie I Stephens +11 more

Accelerated RNA detection using tandem CRISPR nucleases

Nature Chemical Biology(2021)10.1038/s41589-021-00842-2

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0DataRank · unranked

265 citations

Gavin J. Knott, Dylan C. J. Smock, John J. Desmarais, Sungmin Son, Abdul Bhuiya +43 more

Programmable translational inhibition by a molecular glue-oligonucleotide conjugate

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.15.664547

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0DataRank · unranked

0 citations

Joanna Kovalski, Francisco J. Zapatero‐Belinchón, Maxwell R. Bennett, Duygu Kuzuoğlu‐Öztürk, Qiongyu Li +9 more

Rapid assessment of SARS-CoV-2–evolved variants using virus-like particles

Science(2021)10.1126/science.abl6184

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0DataRank · unranked

356 citations

Taha Y. Taha, Takako Tabata, Irene P. Chen, Alison Ciling, Mir M. Khalid +7 more

Identification of a therapeutic interfering particle—A single-dose SARS-CoV-2 antiviral intervention with a high barrier to resistance

Cell(2021)10.1016/j.cell.2021.11.004

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0DataRank · unranked

82 citations

Gustavo Vasen, Michael Pablo, Xinyue Chen, Nathan Beutler, Arjun J. Kumar +13 more

A genome-wide CRISPR screen identifies UFMylation and TRAMP-like complexes as host factors required for hepatitis A virus infection

Cell Reports(2021)10.1016/j.celrep.2021.108859

N/A

0DataRank · unranked

74 citations

Ruofan Wang, Nathan L. Meyers, Mélanie Ott, Andreas S. Puschnik, Jessie Kulsuptrakul

Transmission, infectivity, and neutralization of a spike L452R SARS-CoV-2 variant

Cell(2021)10.1016/j.cell.2021.04.025

N/A

0DataRank · unranked

542 citations

Miguel Garcia-Knight, Mir M. Khalid, Venice Servellita, Candace Wang, Mary Kate Morris +41 more

Novel RT-ddPCR assays for measuring the levels of subgenomic and genomic SARS-CoV-2 transcripts

Methods(2021)10.1016/j.ymeth.2021.04.011

N/A

0DataRank · unranked

38 citations

Holly Anne Martin, Ryan Marczak, Parinaz Fozouni, Albert Vallejo-Gracia, G. Renuka Kumar +6 more

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