Stefan G. Sarafianos

Also affiliated with Children's Healthcare of Atlanta

Immunology and MicrobiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 51 papers. Top paper: “HIV-1 usurps mixed-charge domain-dependent CPSF6 phase separation for higher-order capsid binding, nuclear entry and viral DNA integration”.

HIV-1 usurps mixed-charge domain-dependent CPSF6 phase separation for higher-order capsid binding, nuclear entry and viral DNA integration

Nucleic Acids Research(2024)10.1093/nar/gkae769

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0.535DataRank · unranked

24 citations

Gregory J. Bedwell, Satya P. Singh, Hyun Jae Yu, Bjarki Arnarson, Parmit K. Singh +14 more

Effect of P‐body component Mov10 on HCV virus production and infectivity

The FASEB Journal(2020)10.1096/fj.201800641r

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0DataRank · unranked

17 citations

Tanyaradzwa P. Ndongwe, Maritza Puray‐Chavez, Mary C. Casey, T Izumi, Vinay K. Pathak +3 more

Novel HIV-1 capsid-targeting small molecules of the PF74 binding site

European Journal of Medicinal Chemistry(2020)10.1016/j.ejmech.2020.112626

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28 citations

Mary C. Casey, Sanjeev Kumar V. Vernekar, Rajkumar Lalji Sahani, Jayakanth Kankanala, Karen A. Kirby +8 more

Chemical profiling of HIV-1 capsid-targeting antiviral PF74

European Journal of Medicinal Chemistry(2020)10.1016/j.ejmech.2020.112427

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26 citations

Mary C. Casey, Sanjeev Kumar V. Vernekar, Ha T., Rajkumar Lalji Sahani, Karen A. Kirby +8 more

7-Deaza-7-fluoro modification confers on 4′-cyano-nucleosides potent activity against entecavir/adefovir-resistant HBV variants and favorable safety

Antiviral Research(2020)10.1016/j.antiviral.2020.104744

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7 citations

Nobuyo Higashi‐Kuwata, Debananda Das, Kota Tomaya, Kohei Yamada, Shuko Murakami +7 more

Proteins and Disease | Structural Basis of HIV Reverse Transcription, Inhibition, and Drug Resistance

Elsevier eBooks(2020)10.1016/b978-0-12-809633-8.21570-7

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0DataRank · unranked

1 citations

Karen A. Kirby, Philip R. Tedbury, Stefan G. Sarafianos, Maria E. Cilento

Baicalein and Baicalin Inhibit SARS-CoV-2 RNA-Dependent-RNA Polymerase

Microorganisms(2021)10.3390/microorganisms9050893

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136 citations

Katie Musall, Adrian Oo, Dongdong Cao, Bo Liang, Pouya Hassandarvish +10 more

The SMC5/6 complex compacts and silences unintegrated HIV-1 DNA and is antagonized by Vpr

Cell Host & Microbe(2021)10.1016/j.chom.2021.03.001

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87 citations

Stuart Bloor, James C. Williamson, Sergio Martinez Cuesta, Raven Shah, Ana Teixeira-Silva +6 more

Rotten to the core: antivirals targeting the HIV-1 capsid core

Retrovirology(2021)10.1186/s12977-021-00583-z

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68 citations

Alexa A. Snyder, Karen A. Kirby, Philip R. Tedbury, Monika Raj, Zhengqiang Wang +2 more

Comparison of anti-SARS-CoV-2 activity and intracellular metabolism of remdesivir and its parent nucleoside

Current Research in Pharmacology and Drug Discovery(2021)10.1016/j.crphar.2021.100045

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33 citations

Keivan Zandi, Leda Bassit, Yee Tsuey Ong, Kiran Verma, Peng Liu +10 more

Discovery of New Small Molecule Hits as Hepatitis B Virus Capsid Assembly Modulators: Structure and Pharmacophore-Based Approaches

Viruses(2021)10.3390/v13050770

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18 citations

Haijuan Du, Huanchun Zhang, Karen A. Kirby, Philip R. Tedbury, Jiashu Xie +3 more

Specific mutations in the HIV-1 G-tract of the 3′-polypurine tract cause resistance to integrase strand transfer inhibitors

Journal of Antimicrobial Chemotherapy(2021)10.1093/jac/dkab448

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14 citations

Mai Kubota, Urara Shigemi, Hirotaka Ode, Yoshiyuki Yokomaku, Karen A. Kirby +3 more

Molecular Dynamics Free Energy Simulations Reveal the Mechanism for the Antiviral Resistance of the M66I HIV-1 Capsid Mutation

Viruses(2021)10.3390/v13050920

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18 citations

Ronald M. Levy, Karen A. Kirby, Zhengqiang Wang, Stefan G. Sarafianos, Nanjie Deng +1 more

Design, Synthesis and Characterization of HIV-1 CA-Targeting Small Molecules: Conformational Restriction of PF74

Viruses(2021)10.3390/v13030479

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16 citations

Raquel Diana‐Rivero, Sanjeev Kumar V. Vernekar, Lei Wang, Haijuan Du, Huanchun Zhang +8 more

Potency and metabolic stability: a molecular hybrid case in the design of novel PF74-like small molecules targeting HIV-1 capsid protein

RSC Medicinal Chemistry(2021)10.1039/d1md00292a

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4 citations

Thamina Akther, Maria E. Cilento, Andres Emanuelli Castaner, Huanchun Zhang, Karen A. Kirby +4 more

Subgenomic SARS-CoV-2 replicon and reporter replicon cell lines enable ultrahigh throughput antiviral screening and mechanistic studies with antivirals, viral mutations or host factors that affect COVID-19 replication

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.29.474471

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9 citations

Philip R. Tedbury, Yee Tsuey Ong, Raven Shah, Ryan L. Slack, Maria E. Cilento +10 more

Biochemical and structural insights into SARS-CoV-2 polyprotein processing by Mpro

Science Advances(2022)10.1126/sciadv.add2191

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34 citations

Valentine V. Courouble, Sanjay Kumar Dey, Jerry Joe E.K. Harrison, Jennifer Timm, Jesse B. Hopkins +6 more

Marine Natural Products as Leads against SARS-CoV-2 Infection

Journal of Natural Products(2022)10.1021/acs.jnatprod.2c00015

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35 citations

Philip R. Tedbury, Anne Marie Sweeney-Jones, Luke Mani, Katy Soapi, Candela Manfredi +4 more

TRIM5α Restriction of HIV-1-N74D Viruses in Lymphocytes Is Caused by a Loss of Cyclophilin A Protection

Viruses(2022)10.3390/v14020363

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16 citations

Lacy M. Simons, Karen A. Kirby, Ángel Bulnes‐Ramos, Pan Hu, Stefan G. Sarafianos +3 more

Activation of HIV-1 proviruses increases downstream chromatin accessibility

iScience(2022)10.1016/j.isci.2022.105490

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15 citations

Christian M. Gallardo, Yoonhee Jung, Ben Clock, Jesse R. Dixon, William M. McFadden +7 more

Structure-based virtual screening workflow to identify antivirals targeting HIV-1 capsid

Journal of Computer-Aided Molecular Design(2022)10.1007/s10822-022-00446-5

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8 citations

Avik Biswas, R. S. K. Vijayan, Pierrick Craveur, Stefano Forli, Arthur J. Olson +6 more

Adaptation of HIV-1/HIV-2 Chimeras with Defects in Genome Packaging and Viral Replication

mBio(2022)10.1128/mbio.02220-22

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6 citations

Olga A. Nikolaitchik, Jennifer A. Yoo, Xayathed Somoulay, Matthew Brown, Franck S. Mbuntcha Bogni +6 more

Biochemical and structural insights into SARS-CoV-2 polyprotein processing by Mpro

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.27.493767

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1 citations

Valentine V. Courouble, Sanjay Kumar Dey, Jerry Joe E.K. Harrison, Jennifer Timm, Jesse B. Hopkins +6 more

The HIV-1 capsid core is an opportunistic nuclear import receptor

Nature Communications(2023)10.1038/s41467-023-39146-5

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38 citations

Hyun Jae Yu, Cindy Buffone, Szu‐Wei Huang, Kyeongeun Lee, Shih Lin Goh +7 more

Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization

Nature Communications(2023)10.1038/s41467-023-41197-7

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20 citations

Karen A. Kirby, William M. McFadden, Haijuan Du, Dandan Liu, Chaoyi Xu +10 more

Discovery of Nirmatrelvir Resistance Mutations in SARS-CoV-2 3CLpro: A Computational-Experimental Approach

Journal of Chemical Information and Modeling(2023)10.1021/acs.jcim.3c01269

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17 citations

Robel Demissie, Hyun Lee, Shuiyun Lan, Huanchun Zhang, Stefan G. Sarafianos +3 more

Biology of the hepatitis B virus (HBV) core and capsid assembly modulators (CAMs) for chronic hepatitis B (CHB) cure

Global Health & Medicine(2023)10.35772/ghm.2023.01065

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15 citations

Stefan G. Sarafianos, William M. McFadden

Targeting the HIV-1 and HBV Capsids, an EnCore

Viruses(2023)10.3390/v15040896

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8 citations

Stefan G. Sarafianos, William M. McFadden

SARS-CoV-2 Induces Epithelial-Enteric Neuronal Crosstalk Stimulating VIP Release

Biomolecules(2023)10.3390/biom13020207

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7 citations

Philip R. Tedbury, Simon M. Mwangi, Yunshan Liu, Ge Li, Didier Merlin +5 more

HIV-2 inhibits HIV-1 gene expression via two independent mechanisms during cellular co-infection

Journal of Virology(2023)10.1128/jvi.01870-22

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6 citations

Kinjal Majumder, Philip R. Tedbury, Xin Wen, Yee Tsuey Ong, Marc C. Johnson +2 more

Mechanisms by which the cystic fibrosis transmembrane conductance regulator may influence SARS‐CoV ‐2 infection and COVID ‐19 disease severity

The FASEB Journal(2023)10.1096/fj.202300077r

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5 citations

Candela Manfredi, Frauke Degenhardt, Joseph Conway, Michael Horwath, Courtney McCracken +33 more

Mechanisms of Action of the Host-Targeting Agent Cyclosporin A and Direct-Acting Antiviral Agents against Hepatitis C Virus

Viruses(2023)10.3390/v15040981

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2 citations

Tanya P. Ndongwe, Juan Ji, Andrew D. Huber, Eleftherios Michailidis, Charles M. Rice +4 more

Nirmatrelvir Resistance in SARS-CoV-2 Omicron_BA.1 and WA1 Replicons and Escape Strategies

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2022.12.31.522389

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24 citations

Grace Neilsen, Ryan L. Slack, William A. Cantara, Andres Emanuelli Castaner, Zachary C. Lorson +7 more

HIV-1 resistance to islatravir/tenofovir combination therapy in wild-type or NRTI resistant strains of diverse HIV-1 subtypes

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.18.545484

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3 citations

Xin Wen, Aaron B. Reeve, Obiaara Ukah, Alexa A. Snyder, Ciro M. Carrillo +10 more

TSAR, “Thermal Shift Analysis in R”, identifies endogenous molecules that interact with HIV-1 capsid hexamers

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.29.569293

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1 citations

Xinlin Gao, Zhijiang Ye, Xin Wen, Zachary C. Lorson, Hua Zheng +5 more

State of the ART (antiretroviral therapy): Long-acting HIV-1 therapeutics

Global Health & Medicine(2024)10.35772/ghm.2024.01049

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11 citations

William M. McFadden, Alexa A. Snyder, Stefan G. Sarafianos, S Ravichandran

A Tag‐Free Platform for Synthesis and Screening of Cyclic Peptide Libraries

Angewandte Chemie International Edition(2024)10.1002/anie.202320045

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18 citations

Victor Adebomi, Patrick Czabala, Jonathan Palmer, William M. McFadden, Zachary C. Lorson +5 more

Identification of clickable HIV-1 capsid-targeting probes for viral replication inhibition

Cell chemical biology(2024)10.1016/j.chembiol.2024.02.012

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12 citations

Mary C. Casey, Grant A. L. Bare, Karen A. Kirby, Xin Wen, Gencheng Li +13 more

Design and Synthesis of New GS-6207 Subtypes for Targeting HIV-1 Capsid Protein

International Journal of Molecular Sciences(2024)10.3390/ijms25073734

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9 citations

William M. McFadden, Huanchun Zhang, Karen A. Kirby, Stefan G. Sarafianos, Zhengqiang Wang +1 more

Synthesis and biological evaluation of novel peptidomimetic inhibitors of the coronavirus 3C-like protease

European Journal of Medicinal Chemistry(2024)10.1016/j.ejmech.2024.116263

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9 citations

Julia C. LeCher, Ramyani De, Shaoman Zhou, Peng Liu, Shu Ling Goh +15 more

A Tag‐Free Platform for Synthesis and Screening of Cyclic Peptide Libraries

Angewandte Chemie(2024)10.1002/ange.202320045

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3 citations

Victor Adebomi, Patrick Czabala, Jonathan Palmer, William M. McFadden, Zachary C. Lorson +5 more

Dimming the corona: studying SARS-coronavirus-2 at reduced biocontainment level using replicons and virus-like particles

mBio(2024)10.1128/mbio.03368-23

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1 citations

Asha Maria Mathew, J.M. Castro, William M. McFadden, Xin Wen, Yee Tsuey Ong +4 more

Disruption of LEDGF/p75-directed integration derepresses antisense transcription of the HIV-1 genome

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.12.06.627169

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3 citations

Darius Mahboubi, Maritza Puray‐Chavez, Raven Shah, Obiaara B. Ukah, Claudia C. Wahoski +14 more

Adapting a trapped ion mobility spectrometry-Q-TOF mass spectrometer for native mass spectrometry

ChemRxiv(2024)10.26434/chemrxiv-2024-xmjml-v3

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0DataRank · unranked

0 citations

Benjamin Jones, Mark E. Ridgeway, Erin Panczyk, Árpád Somogyi, Desmond A. Kaplan +8 more

Adapting a Trapped Ion Mobility Spectrometry-Q-TOF for High m/z Native Mass Spectrometry and Surface-Induced Dissociation

Analytical Chemistry(2025)10.1021/acs.analchem.4c03557

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10 citations

Benjamin J. Jones, Mark E. Ridgeway, Erin Panczyk, Árpád Somogyi, Desmond A. Kaplan +8 more

Strategy to overcome a nirmatrelvir resistance mechanism in the SARS-CoV-2 nsp5 protease

Science Advances(2025)10.1126/sciadv.adv8875

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0DataRank · unranked

10 citations

Shuiyun Lan, Ryan L. Slack, Zachary C. Lorson, Andres Emanuelli Castaner, Rachel Lee +13 more

Considerations for capsid-targeting antiretrovirals in pre-exposure prophylaxis

Trends in Molecular Medicine(2025)10.1016/j.molmed.2025.01.013

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5 citations

Mia Færch, Karen A. Kirby, Robert A. Dick, Bruce E. Torbett, Stefan G. Sarafianos +1 more

Monkeypox Virus Is Inhibited by Nucleoside Analogues Including the Acyclic Phosphonates Adefovir and Tenofovir In Vitro

Journal of Medical Virology(2025)10.1002/jmv.70669

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1 citations

Huanchun Zhang, Emerson Ailidh Boggs, Jesse Kilcullen, Margaret Moriarty, Yuhong Du +7 more

Structural, biophysical, and virological mechanistic characterization of HIV-1 capsid-targeting antivirals

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.64898/2025.12.30.696960

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1 citations

William M. McFadden, Lin Wang, Haijuan Du, Huanchun Zhang, Andres Emanuelli Castaner +16 more

HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains

Nature Communications(2020)10.1038/s41467-020-17256-8

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172 citations

Mariana Marin, Parmit K. Singh, Vasudevan Achuthan, M Prellberg, Kristina Palermino-Rowland +6 more

Translocation of HIV capsid core through the Nuclear Pore Complex by affinity gradient

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.02.680059

N/A

0DataRank · unranked

0 citations

Ryan L. Slack, Zachary C. Lorson, Andres Emanuelli Castaner, Krisztina Ambrus, Jonathan S. Winkjer +4 more