Tudor I. Oprea

Also affiliated with Hydrologic Research Center

Computer ScienceBiochemistry, Genetics and Molecular BiologyPharmacology, Toxicology and PharmaceuticsChemistry

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

24.8Author DataRank

Indexed papers

13in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 13 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

DrugCentral 2021 supports drug discovery and repositioning

Nucleic Acids Research(2020)10.1093/nar/gkaa997

Top 4%

5.5DataRank

Top 4%207 citations

Cristian Bologa, Jayme Holmes, Giovanni Bocci, Thomas B. Wilson, Ðắc-Trung Nguyễn +9 more

Papers

Driven by 60 papers — median percentile 87. Top paper: “DrugCentral 2021 supports drug discovery and repositioning”.

DrugCentral 2021 supports drug discovery and repositioning

Nucleic Acids Research(2020)10.1093/nar/gkaa997

Top 4%

5.5DataRank

Top 4%207 citations

Cristian Bologa, Jayme Holmes, Giovanni Bocci, Thomas B. Wilson, Ðắc-Trung Nguyễn +9 more

TCRD and Pharos 2021: mining the human proteome for disease biology

Nucleic Acids Research(2020)10.1093/nar/gkaa993

Top 5%

4.2DataRank

Top 5%177 citations

Stephen L. Mathias, Keith J. Kelleher, Vishal B. Siramshetty, Ðắc-Trung Nguyễn, Cristian Bologa +14 more

DrugCentral 2023 extends human clinical data and integrates veterinary drugs

Nucleic Acids Research(2022)10.1093/nar/gkac1085

Top 8%

2.7DataRank

Top 8%92 citations

Thomas B. Wilson, Ramona Curpăn, Liliana Halip, Ana Borota, Alina Bora +6 more

Mondo: Unifying diseases for the world, by the world

medRxiv(2022)10.1101/2022.04.13.22273750

Top 8%

2.7DataRank

Top 8%104 citations

Nicolas A Matentzoglu, Sabrina Toro, Joseph E Flack, Harshad Hegde, Deepak R Unni +83 more

Diseases 2.0: a weekly updated database of disease–gene associations from text mining and data integration

Database(2022)10.1093/database/baac019

Top 9%

2.3DataRank

Top 9%140 citations

Alexander Junge, Tudor I. Oprea, Lars Juhl Jensen, Dhouha Grissa

Pharos 2023: an integrated resource for the understudied human proteome

Nucleic Acids Research(2022)10.1093/nar/gkac1033

Top 9%

2.3DataRank

Top 9%133 citations

Timothy Sheils, Stephen L. Mathias, Jeremy J. Yang, Vincent T. Metzger, Vishal B. Siramshetty +12 more

Deciphering the Plasma Proteome of Type 2 Diabetes

Diabetes(2020)10.2337/db20-0296

N/A

2.0DataRank · unranked

64 citations

Christian Jonasson, Cornelia Huth, Rory Wilson, Christian Gieger, Pamela Matias +15 more

Illuminating the druggable genome through patent bioactivity data

PeerJ(2023)10.7717/peerj.15153

Top 13%

1.5DataRank

Top 13%12 citations

Anna Gaulton, Eloy Félix, Tevfik Kizilören, Ricardo Arcila, Tudor I. Oprea +2 more

Machine learning prediction and tau-based screening identifies potential Alzheimer’s disease genes relevant to immunity

Communications Biology(2022)10.1038/s42003-022-03068-7

Top 15%

1.4DataRank

Top 15%52 citations

Oleg Ursu, Cristian Bologa, Shanya Jiang, Nicole Maphis, Somayeh Dadras +8 more

QSAR without borders

Chemical Society Reviews(2020)10.1039/d0cs00098a

N/A

1.0DataRank · unranked

870 citations

Jürgen Bajorath, Robert P. Sheridan, Igor V. Tetko, Dmitry Filimonov, Vladimir Poroikov +14 more

Artificial Intelligence for Drug Discovery: Are We There Yet?

The Annual Review of Pharmacology and Toxicology(2023)10.1146/annurev-pharmtox-040323-040828

N/A

0.806DataRank · unranked

214 citations

Tudor I. Oprea, Catrin Hasselgren

A critical overview of computational approaches employed for COVID-19 drug discovery

Chemical Society Reviews(2021)10.1039/d0cs01065k

N/A

0.804DataRank · unranked

212 citations

Rommie E. Amaro, Carolina Horta Andrade, Nathan Brown, Sean Ekins, Denis Fourches +14 more

Interpretable deep learning translation of GWAS and multi-omics findings to identify pathobiology and drug repurposing in Alzheimer’s disease

Cell Reports(2022)10.1016/j.celrep.2022.111717

N/A

0.702DataRank · unranked

107 citations

Chengsheng Mao, Yuan Hou, Yuan Luo, Jessica Binder, Yadi Zhou +12 more

AlphaFold illuminates half of the dark human proteins

Current Opinion in Structural Biology(2022)10.1016/j.sbi.2022.102372

N/A

0.678DataRank · unranked

91 citations

Joel Berendzen, Amy O. Stevens, Yi He, Jian Wang, Nikolay V. Dokholyan +2 more

Overview of the Knowledge Management Center for Illuminating the Druggable Genome

Drug Discovery Today(2024)10.1016/j.drudis.2024.103882

Top 30%

0.678DataRank

Top 30%13 citations

Cristian Bologa, Jayme Holmes, Stephen L. Mathias, Vincent T. Metzger, Anna Waller +9 more

Crowdsourced mapping of unexplored target space of kinase inhibitors

Nature Communications(2021)10.1038/s41467-021-23165-1

N/A

0.675DataRank · unranked

89 citations

Balaguru Ravikumar, Robert J. Allaway, Fang Wan, Sung‐Joon Park, Olexandr Isayev +94 more

A machine learning platform to estimate anti-SARS-CoV-2 activities

Nature Machine Intelligence(2021)10.1038/s42256-021-00335-w

N/A

0.648DataRank · unranked

74 citations

Giovanni Bocci, Srijan Verma, Md Mahmudulla Hassan, Jayme Holmes, Jeremy J. Yang +3 more

Extensive identification of genes involved in congenital and structural heart disorders and cardiomyopathy

Nature Cardiovascular Research(2022)10.1038/s44161-022-00018-8

N/A

0.635DataRank · unranked

68 citations

Gregor Miller, Tudor I. Oprea, Chih‐Wei Hsu, Gisela Fobo, Goar Frishman +95 more

Crowdsourced mapping extends the target space of kinase inhibitors

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2019.12.31.891812

N/A

0.552DataRank · unranked

11 citations

Balaguru Ravikumar, Robert J. Allaway, Sung‐Joon Park, Fang Wan, Olexandr Isayev +22 more

Getting Started with the IDG KMC Datasets and Tools

Current Protocols(2022)10.1002/cpz1.355

Top 38%

0.511DataRank

Top 38%12 citations

Jessica Binder, Jeremy J. Yang, Jayme Holmes, Alexander Lachmann, Daniel J. B. Clarke +7 more

Toxicology knowledge graph for structural birth defects

Communications Medicine(2023)10.1038/s43856-023-00329-2

N/A

0.470DataRank · unranked

22 citations

Daniel J. B. Clarke, Zhuorui Xie, Giacomo B. Marino, Vivian Utti, Sherry L. Jenkins +13 more

Exploring DrugCentral: from molecular structures to clinical effects

Journal of Computer-Aided Molecular Design(2023)10.1007/s10822-023-00529-x

Top 42%

0.444DataRank

Top 42%10 citations

Sorin Avram, Ramona Curpăn, Ana Borota, Alina Bora, Cristian Bologa +2 more

Mondo: integrating disease terminology across communities

Genetics(2025)10.1093/genetics/iyaf215

N/A

0.425DataRank · unranked

16 citations

Sabrina Toro, Nicolas A Matentzoglu, Joseph E Flack, Kathleen R. Mullen, Harshad Hegde +95 more

CACHE (Critical Assessment of Computational Hit-finding Experiments): A public-private partnership benchmarking initiative to enable the development of computational methods for hit-finding

UCL Discovery (University College London)(2021)10.33774/chemrxiv-2021-rzq4n

N/A

0.396DataRank · unranked

13 citations

Rima Al‐awar, Rommie E. Amaro, C.H. Arrowsmith, Hátylas Azevedo, Robert A. Batey +34 more

Formalizing drug indications on the road to therapeutic intent

Journal of the American Medical Informatics Association(2017)10.1093/jamia/ocx064

N/A

0.345DataRank · unranked

9 citations

Tudor I. Oprea, Oleg Ursu, Cristian G Bologa, Amrapali Zaveri, Jayme Holmes +7 more

Node-degree aware edge sampling mitigates inflated classification performance in biomedical random walk-based graph representation learning

Bioinformatics Advances(2024)10.1093/bioadv/vbae036

N/A

0.330DataRank · unranked

8 citations

Lauren Rekerle, Tommaso Fontana, Peter Hansen, Elena Casiraghi, Vida Ravanmehr +12 more

Supervised learning with word embeddings derived from PubMed captures latent knowledge about protein kinases and cancer

NAR Genomics and Bioinformatics(2021)10.1093/nargab/lqab113

N/A

0.312DataRank · unranked

7 citations

Hannah Blau, Luca Cappelletti, Tommaso Fontana, Leigh C Carmody, Ben D Coleman +13 more

Autophagy dark genes: Can we find them with machine learning?

Natural Sciences(2023)10.1002/ntls.20220067

N/A

0.292DataRank · unranked

6 citations

Jeremy J. Yang, Praveen Kumar, Daniel R. Byrd, Elaine L. Bearer, Tudor I. Oprea +1 more

TIN-X version 3: update with expanded dataset and modernized architecture for enhanced illumination of understudied targets

PeerJ(2024)10.7717/peerj.17470

N/A

0.269DataRank · unranked

4 citations

Daniel C. Cannon, Jeremy J. Yang, Stephen L. Mathias, Cristian Bologa, Anna Waller +9 more

A Workflow of Integrated Resources to Catalyze Network Pharmacology Driven COVID-19 Research

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.04.369041

N/A

0.241DataRank · unranked

4 citations

Vishal B. Siramshetty, Praveen Kumar, Manideep Gurumurthy, Busola Grillo, Biju Mathew +14 more

Illuminating the Druggable Genome through Patent Bioactivity Data

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.15.500187

Top 62%

0.226DataRank

Top 62%2 citations

Anna Gaulton, Eloy Félix, Tevfik Kizilören, Ricardo Arcila, Tudor I. Oprea +2 more

DISEASES 2.0: a weekly updated database of disease–gene associations from text mining and data integration

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.07.471296

Top 63%

0.211DataRank

Top 63%2 citations

Alexander Junge, Tudor I. Oprea, Lars Juhl Jensen, Dhouha Grissa

A machine learning platform to estimate anti-SARS-CoV-2 activities

ChemRxiv(2021)10.26434/chemrxiv.12915779.v3

N/A

0.197DataRank · unranked

2 citations

Giovanni Bocci, Srijan Verma, Mahmudulla Hassan, Jayme Holmes, Jeremy J. Yang +3 more

InContext: curation of medical context for drug indications

Journal of Biomedical Semantics(2021)10.1186/s13326-021-00234-4

N/A

0.165DataRank · unranked

2 citations

Linda Rieswijk, Tudor I. Oprea, Michel J. Dumontier, Kody Moodley

ReproTox-KG: Toxicology Knowledge Graph for Structural Birth Defects

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.15.508198

N/A

0.104DataRank · unranked

1 citations

Daniel J. B. Clarke, Zhuorui Xie, Giacomo B. Marino, Vivian Utti, Taha M. Ahooyi +13 more

Node-degree aware edge sampling mitigates inflated classification performance in biomedical graph representation learning

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.21.517376

N/A

0.104DataRank · unranked

1 citations

Lauren Rekerle, Tommaso Fontana, Peter Hansen, Elena Casiraghi, Vida Ravanmehr +12 more

Supervised learning with word embeddings derived from PubMed captures latent knowledge about protein kinases and cancer

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.11.447943

N/A

0.104DataRank · unranked

1 citations

Hannah Blau, Luca Cappelletti, Tommaso Fontana, Leigh C Carmody, Ben D Coleman +12 more

GLUT3 inhibitor discovery through in silico ligand screening and in vivo validation in eukaryotic expression systems

Scientific Reports(2022)10.1038/s41598-022-05383-9

N/A

0DataRank · unranked

20 citations

Giovanni Bocci, Mohd Ishtikhar, Moumita Khamrai, Mislav Oreb, Tudor I. Oprea +2 more

Novel drug targets in 2021

Nature Reviews Drug Discovery(2022)10.1038/d41573-022-00057-7

N/A

0DataRank · unranked

13 citations

Liliana Halip, Ramona Curpăn, Tudor I. Oprea, Sorin Avram

CACHE (Critical Assessment of Computational Hit-finding Experiments): A public-private partnership benchmarking initiative to enable the development of computational methods for hit-finding

ChemRxiv(2021)10.26434/chemrxiv-2021-rzq4n

N/A

0DataRank · unranked

0 citations

Rima Al‐awar, Rommie E. Amaro, C.H. Arrowsmith, Hátylas Azevedo, Robert A. Batey +34 more

A Workflow of Integrated Resources to Catalyze Network Pharmacology Driven COVID-19 Research

Journal of Chemical Information and Modeling(2022)10.1021/acs.jcim.1c00431

N/A

0DataRank · unranked

8 citations

Vishal B. Siramshetty, Praveen Kumar, Manideep Gurumurthy, Busola Grillo, Biju Mathew +14 more

Annotating off-label drug usage from unconventional sources

medRxiv(2022)10.1101/2022.09.08.22279709

N/A

0DataRank · unranked

4 citations

Liliana Halip, Ramona Curpăn, Ana Borota, Alina Bora, Tudor I. Oprea +1 more

Title: Identification of new GLUT2-selective inhibitors through in silico ligand screening and validation in eukaryotic expression systems

Research Square(2021)10.21203/rs.3.rs-489875/v1

N/A

0DataRank · unranked

0 citations

Oleg Ursu, Cristina V. Iancu, Mislav Oreb, Tudor I. Oprea, Jun‐yong Choe +1 more

A machine learning platform to estimate anti-SARS-CoV-2 activities

ChemRxiv(2020)10.26434/chemrxiv.12915779

N/A

0DataRank · unranked

6 citations

Giovanni Bocci, Srijan Verma, Mahmudulla Hassan, Jayme Holmes, Jeremy J. Yang +3 more

Surely you are joking, Mr Docking!

Chemical Society Reviews(2023)10.1039/d2cs00948j

N/A

0DataRank · unranked

33 citations

Tudor I. Oprea, Alexander Tropsha, Artem Cherkasov, Francesco Gentile

REDIAL-2020: A suite of machine learning models to estimate Anti-SARS-CoV-2 activities

PubMed(2020)10.21203/rs.3.rs-76894/v1

N/A

0DataRank · unranked

6 citations

Giovanni Bocci, Srijan Verma, Md. Rakibul Hassan, Jayme Holmes, Jeremy J. Yang +3 more

SmartGraph: a network pharmacology investigation platform

Journal of Cheminformatics(2020)10.1186/s13321-020-0409-9

N/A

0DataRank · unranked

33 citations

Timothy Sheils, Tudor I. Oprea, Gergely Zahoránszky-Köhalmi

Artificial intelligence, drug repurposing and peer review

Nature Biotechnology(2020)10.1038/s41587-020-0686-x

N/A

0DataRank · unranked

78 citations

Tudor I. Oprea, Sagie Davidovich, Thomas Clozel, John P. Overington, Quentin Vanhaelen +4 more

Prevalent mouse phenotypes in the unexplored druggable genome

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.08.467777

N/A

0DataRank · unranked

0 citations

Zicheng Hu, Tudor I. Oprea, K. C. Kent Lloyd, Shawn M. Gomez, Bryan L. Roth +2 more

Molecular Complexity: You Know It When You See It

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.3c01507

N/A

0DataRank · unranked

31 citations

Cristian Bologa, Tudor I. Oprea

Will Artificial Intelligence for Drug Discovery Impact Clinical Pharmacology?

Clinical Pharmacology & Therapeutics(2020)10.1002/cpt.1795

N/A

0DataRank · unranked

151 citations

Quentin Vanhaelen, Tudor I. Oprea, Alex Zhavoronkov

A critical overview of computational approaches employed for COVID-19 drug discovery

UNC Libraries(2024)10.17615/bwe6-fp72

N/A

0DataRank · unranked

5 citations

Kenneth M. Merz, Matthew H. Todd, José L. Medina‐Franco, Sean Ekins, Alexey Zakharov +14 more

SmartGraph API: ProgrammaticKnowledge Mining in Network-Pharmacology Setting

ChemRxiv(2024)10.26434/chemrxiv-2024-0psx3

N/A

0DataRank · unranked

0 citations

Brandon Walker, Nathan Miller, Brett Yang, Dhatri V. L. Penna, Jessica Binder +10 more

SmartGraph API: Programmatic Knowledge Mining in Network-Pharmacology Setting

Journal of Chemical Information and Modeling(2024)10.1021/acs.jcim.4c00789

N/A

0DataRank · unranked

0 citations

Brandon Walker, Nathan Miller, Brett Yang, Dhatri V. L. Penna, Jessica Maine +10 more

TIGA: target illumination GWAS analytics

Bioinformatics(2021)10.1093/bioinformatics/btab427

N/A

0DataRank · unranked

18 citations

Dhouha Grissa, Christophe G. Lambert, Cristian Bologa, Stephen L. Mathias, Anna Waller +4 more

CACHE Challenge #3: Targeting the Nsp3 Macrodomain of SARS-CoV-2

ChemRxiv(2025)10.26434/chemrxiv-2025-d1v7v

N/A

0DataRank · unranked

0 citations

Madhushika Silva, G.J. Correy, Abd Al‐Aziz A. Abu‐Saleh, Suzanne Ackloo, C. Arrowsmith +74 more

Identification of new GLUT2-selective inhibitors through in silico ligand screening and validation in eukaryotic expression systems

Scientific Reports(2021)10.1038/s41598-021-93063-5

N/A

0DataRank · unranked

21 citations

Oleg Ursu, Cristina V. Iancu, Mislav Oreb, Tudor I. Oprea, Jun‐yong Choe +1 more

A systems chemical biology study of malate synthase and isocitrate lyase inhibition in Mycobacterium tuberculosis during active and NRP growth

UNC Libraries(2020)10.17615/3at9-jd55

N/A

0DataRank · unranked

0 citations

Elebeoba E. May, Tudor I. Oprea, Andrei Leitão, Alexander Tropsha

TIGA: Target illumination GWAS analytics

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.11.378596

N/A

0DataRank · unranked

0 citations

Dhouha Grissa, Christophe G. Lambert, Cristian Bologa, Stephen L. Mathias, Anna Waller +4 more

REDIAL-2020: A Suite of Machine Learning Models to Estimate Anti-SARS-CoV-2 Activities

ChemRxiv(2020)10.26434/chemrxiv.12915779.v2

N/A

0DataRank · unranked

1 citations

Giovanni Bocci, Srijan Verma, Mahmudulla Hassan, Jayme Holmes, Jeremy J. Yang +3 more

Tudor I. Oprea

Indexed papers

Top data-sharing exemplar

Papers