Jillian Caiazzi

University of Massachusetts Chan Medical School

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 14 papers. Top paper: “The chemical structure and phosphorothioate content of hydrophobically modified siRNAs impact extrahepatic distribution and efficacy”.

The chemical structure and phosphorothioate content of hydrophobically modified siRNAs impact extrahepatic distribution and efficacy

Nucleic Acids Research(2020)10.1093/nar/gkaa595

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0DataRank · unranked

76 citations

Jillian Caiazzi, Sarah M. Davis, Nicholas McHugh, Jacquelyn Sousa, Anastasia Khvorova +1 more

Docosanoic acid conjugation to siRNA enables functional and safe delivery to skeletal and cardiac muscles

Molecular Therapy(2020)10.1016/j.ymthe.2020.12.023

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76 citations

Jillian Caiazzi, Nicholas McHugh, Vignesh Hariharan, Manish Muhuri, Anastasia Khvorova +1 more

Comparative route of administration studies using therapeutic siRNAs show widespread gene modulation in Dorset sheep

JCI Insight(2021)10.1172/jci.insight.152203

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29 citations

Bruno M.D.C. Godinho, Julia F. Alterman, Andrew H. Coles, Matthew Hassler, Dimas Echeverria +13 more

Structurally constrained phosphonate internucleotide linkage impacts oligonucleotide-enzyme interaction, and modulates siRNA activity and allele specificity

Nucleic Acids Research(2021)10.1093/nar/gkab1126

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20 citations

Samuel Hildebrand, Sarah M. Davis, Rachael Miller, Faith Conroy, Ellen Sapp +10 more

PK-modifying anchors significantly alter clearance kinetics, tissue distribution, and efficacy of therapeutics siRNAs

Molecular Therapy — Nucleic Acids(2022)10.1016/j.omtn.2022.06.005

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27 citations

Emily G. Knox, Samuel Hildebrand, James W. Gilbert, Dimas Echeverria, Zachary Kennedy +9 more

Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2219523120

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48 citations

Minwook Shin, Ching‐Wen Chang, Daniel O’Reilly, Annabelle Biscans, Ken Yamada +41 more

Single intravitreal administration of a tetravalent siRNA exhibits robust and efficient gene silencing in mouse and pig photoreceptors

Molecular Therapy — Nucleic Acids(2023)10.1016/j.omtn.2023.102088

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16 citations

Jillian Caiazzi, Annabelle Biscans, Julia F. Alterman, Dimas Echeverria, Nicholas McHugh +7 more

Extended Nucleic Acid (exNA): A Novel, Biologically Compatible Backbone that Significantly Enhances Oligonucleotide Efficacy in vivo

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.26.542506

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7 citations

Vignesh Hariharan, Jillian Caiazzi, Rachael Miller, Chantal Furguson, Ellen Sapp +18 more

Extended Nucleic Acid (exNA): A Novel, Biologically Compatible Backbone that Significantly Enhances Oligonucleotide Efficacy in vivo

Research Square(2023)10.21203/rs.3.rs-2987323/v1

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4 citations

Jillian Caiazzi, Rachael Miller, Chantal Ferguson, Ellen Sapp, Hassan Fakih +18 more

Single intravitreal administration of a tetravalent siRNA exhibits robust and efficient gene silencing in rodent and swine photoreceptors

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.20.558641

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0DataRank · unranked

0 citations

Jillian Caiazzi, Annabelle Biscans, Julia F. Alterman, Dimas Echeverria, Nicholas McHugh +7 more

Phosphatidylcholine head group chemistry alters the extrahepatic accumulation of lipid-conjugated siRNA

Molecular Therapy — Nucleic Acids(2024)10.1016/j.omtn.2024.102230

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5 citations

Takahiro Nakamura, Minwook Shin, Qi Tang, Vyankat A. Sontakke, Jillian Caiazzi +4 more

An Aptamer‐Based EXACT Anticoagulant as a Sustainable, Animal‐Free Alternative to Unfractionated Heparin

Advanced Science(2025)10.1002/advs.202509867

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1 citations

George A. Pitoc, Manqi Zhang, Jeffrey Clancy, James W. Frederiksen, Amy Yan +7 more

Potent and durable gene modulation in heart and muscle with chemically defined lipophilic siRNAs

Nucleic Acids Research(2025)10.1093/nar/gkaf1374

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1 citations

Clemens Lochmann, Rosemary Gagnon, Ashley Summers, Jillian Caiazzi, Julianna Buchwald +15 more

Single-dose administration of therapeutic divalent siRNA targeting MECP2 prevents lethality for one year in an MECP2 duplication mouse model

Research Square(2025)10.21203/rs.3.rs-6465542/v1

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0DataRank · unranked

0 citations

Ashley Summers, Amy E. Clipperton‐Allen, Jillian Caiazzi, Samuel Hildebrand, Daniel O’Reilly +11 more