Gang Greg Wang

Also affiliated with Duke Medical Center

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 58 papers. Top paper: “DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation”.

DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation

Nature Communications(2021)10.1038/s41467-021-22665-4

N/A

0.722DataRank · unranked

122 citations

Huitao Fan, Sara A. Grimm, Jae Jin Kim, Linhui Li, Yiran Guo +21 more

Structural basis for the H2AK119ub1-specific DNMT3A-nucleosome interaction

Nature Communications(2024)10.1038/s41467-024-50526-3

N/A

0.704DataRank · unranked

26 citations

Yiran Guo, Ting Zhao, Jiuwei Lu, Jian Fang, Yinsheng Wang +3 more

REPROGRAMMING CBX8-PRC1 FUNCTION WITH A POSITIVE ALLOSTERIC MODULATOR

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.23.432388

N/A

0.208DataRank · unranked

3 citations

Daniel Bsteh, Yibo Si, Bryce Hart, Tyler Weaver, Carina Pribitzer +22 more

The sotos syndrome gene Nsd1 safeguards developmental gene enhancers poised for transcription by maintaining the precise deposition of histone methylation

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.108423

N/A

0.176DataRank · unranked

2 citations

Zhucui Li, Jiekai Yin, Yinsheng Wang, Deyou Zheng, Ling Cai +2 more

Epigenetic Control of Cdkn2a.Arf Protects Tumor-Infiltrating Lymphocytes from Metabolic Exhaustion

Cancer Research(2020)10.1158/0008-5472.can-20-0524

N/A

0DataRank · unranked

30 citations

Bradley D. Shields, Erin M. Taylor, Aaron J. Storey, Stephanie D. Byrum, Allen Gies +14 more

Mechanistic insights into chromatin targeting by leukemic NUP98-PHF23 fusion

Nature Communications(2020)10.1038/s41467-020-17098-4

N/A

0DataRank · unranked

27 citations

Yiran Guo, Sheryl M. Gough, Jinyong Zhang, Kendra R. Vann, Kuai Li +6 more

Targeting EZH2 and PRC2 dependence as novel anticancer therapy

UNC Libraries(2020)10.17615/98b2-s982

N/A

0DataRank · unranked

7 citations

Kyle D. Konze, Jian Jin, Gang Greg Wang, Bowen Xu

Histone modifications change with age, dietary restriction and rapamycin treatment in mouse brain

UNC Libraries(2020)10.17615/qvzg-4p31

N/A

0DataRank · unranked

3 citations

Robin P. Ertl, Gang Greg Wang, Clinton M. Astle, X.Z. Shawn Xu, David E. Harrison +2 more

An Orally Bioavailable Chemical Probe of the Lysine Methyltransferases EZH2 and EZH1

Figshare(2020)10.17615/q3bp-3c89

N/A

0DataRank · unranked

3 citations

Feng Liu, Masoud Vedadi, Kyle D. Konze, C.H. Arrowsmith, Gang Greg Wang +18 more

Direct readout of heterochromatic H3K9me3 regulates DNMT1-mediated maintenance DNA methylation

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.27.064493

N/A

0DataRank · unranked

11 citations

Huitao Fan, Sara A. Grimm, Yiran Guo, Jae Jin Kim, Linhui Li +20 more

Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.27.064386

N/A

0DataRank · unranked

2 citations

Max Emperle, Yiran Guo, Sara A. Grimm, Wendan Ren, Sabrina Adam +15 more

YY1 cistrome analysis uncovers an essential requirement of the YY1:BRD4-PFKP regulatory axis for promoting tumorigenesis of castration-resistant prostate cancer

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.17.302596

N/A

0DataRank · unranked

0 citations

Yi‐Hsuan Tsai, Phillip M. Galbo, Weida Gong, Aaron J. Storey, Yuemei Xu +12 more

BPTF Is Essential for T Cell Homeostasis and Function

UNC Libraries(2020)10.17615/get8-vg29

N/A

0DataRank · unranked

0 citations

Yisong Y. Wan, Yunqi Wang, Gang Greg Wang, Bing Wu, Chaojun Wang

An Allosteric Interaction Links USP7 to Deubiquitination and Chromatin Targeting of UHRF1

UNC Libraries(2020)10.17615/v54g-vw65

N/A

0DataRank · unranked

0 citations

Lin Li, Yinsheng Wang, Jikui Song, David F. Allison, Scott B. Rothbart +5 more

Bmi1 Is a Key Epigenetic Barrier to Direct Cardiac Reprogramming

UNC Libraries(2020)10.17615/jgv0-pk80

N/A

0DataRank · unranked

0 citations

Gang Greg Wang, Chaoying Yin, Ji‐Dong Fu, Qian Li, Sahar Alimohamadi +6 more

NUP98-PHF23 Is a Chromatin-Modifying Oncoprotein That Causes a Wide Array of Leukemias Sensitive to Inhibition of PHD Histone Reader Function

UNC Libraries(2020)10.17615/tzed-va89

N/A

0DataRank · unranked

0 citations

Sheryl M. Gough, John M. Denu, Paul S. Meltzer, Masahiro Onozawa, Fan Yang +11 more

Phase separation drives aberrant chromatin looping and cancer development

Nature(2021)10.1038/s41586-021-03662-5

N/A

0DataRank · unranked

470 citations

Eric S. Davis, Timothy A. Daugird, Shuai Zhao, Ivana Yoseli Quiroga, Hidetaka Uryu +14 more

The language of chromatin modification in human cancers

Nature reviews. Cancer(2021)10.1038/s41568-021-00357-x

N/A

0DataRank · unranked

410 citations

C. David Allis, Gang Greg Wang, Shuai Zhao

Polycomb Gene Silencing Mechanisms: PRC2 Chromatin Targeting, H3K27me3 'Readout', and Phase Separation-Based Compaction

Trends in Genetics(2021)10.1016/j.tig.2020.12.006

N/A

0DataRank · unranked

184 citations

Shuai Zhao, Gang Greg Wang, Yiran Guo

A selective WDR5 degrader inhibits acute myeloid leukemia in patient-derived mouse models

Science Translational Medicine(2021)10.1126/scitranslmed.abj1578

N/A

0DataRank · unranked

158 citations

Dongxu Li, Jithesh Kottur, Yudao Shen, Huen Suk Kim, Kwang‐Su Park +14 more

Harnessing the E3 Ligase KEAP1 for Targeted Protein Degradation

Journal of the American Chemical Society(2021)10.1021/jacs.1c04841

N/A

0DataRank · unranked

144 citations

Fanye Meng, Kwang‐Su Park, Hyerin Yim, Julia Velez, Prashasti Kumar +11 more

A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells

Cell chemical biology(2021)10.1016/j.chembiol.2021.08.004

N/A

0DataRank · unranked

62 citations

Fanye Meng, Kwang‐Su Park, Aaron J. Storey, Weida Gong, Yi‐Hsuan Tsai +12 more

Cistrome analysis of YY1 uncovers a regulatory axis of YY1:BRD2/4-PFKP during tumorigenesis of advanced prostate cancer

Nucleic Acids Research(2021)10.1093/nar/gkab252

N/A

0DataRank · unranked

53 citations

Yi‐Hsuan Tsai, Phillip M. Galbo, Weida Gong, Aaron J. Storey, Yuemei Xu +13 more

ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanism

Nature Communications(2021)10.1038/s41467-021-21357-3

N/A

0DataRank · unranked

42 citations

Phillip M. Galbo, Weida Gong, Aaron J. Storey, Yi‐Hsuan Tsai, Xufen Yu +13 more

R-loop and its functions at the regulatory interfaces between transcription and (epi)genome

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms(2021)10.1016/j.bbagrm.2021.194750

N/A

0DataRank · unranked

44 citations

Gang Greg Wang, Arum Kim

A conserved BAH module within mammalian BAHD1 connects H3K27me3 to Polycomb gene silencing

Nucleic Acids Research(2021)10.1093/nar/gkab210

N/A

0DataRank · unranked

30 citations

Yiran Guo, Yi‐Hsuan Tsai, Aaron J. Storey, Arum Kim, Weida Gong +8 more

EZH2 noncanonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis

Nature Cell Biology(2022)10.1038/s41556-022-00850-x

N/A

0DataRank · unranked

184 citations

Xufen Yu, Weida Gong, Xijuan Liu, Kwang‐Su Park, Anqi Ma +12 more

Discovery of a First-in-Class Degrader for Nuclear Receptor Binding SET Domain Protein 2 (NSD2) and Ikaros/Aiolos

Journal of Medicinal Chemistry(2022)10.1021/acs.jmedchem.2c00807

N/A

0DataRank · unranked

58 citations

Chenxi Xu, Kwang‐Su Park, H. Ümit Kanıskan, Gang Greg Wang, Jian Jin +1 more

Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic

Oncogene(2022)10.1038/s41388-022-02340-8

N/A

0DataRank · unranked

56 citations

Xufen Yu, Jithesh Kottur, Weida Gong, Zhao Zhang, Aaron J. Storey +14 more

A cryptic transactivation domain of EZH2 binds AR and AR’s splice variant, promoting oncogene activation and tumorous transformation

Nucleic Acids Research(2022)10.1093/nar/gkac861

N/A

0DataRank · unranked

41 citations

Kwang‐Su Park, Xufen Yu, Weida Gong, H. Shelton Earp, Gang Greg Wang +3 more

DOT1L activity in leukemia cells requires interaction with ubiquitylated H2B that promotes productive nucleosome binding

Cell Reports(2022)10.1016/j.celrep.2022.110369

N/A

0DataRank · unranked

24 citations

Satya P. Yadav, Dongxu Li, Carinne N. Geil, C. B. Smith, Gang Greg Wang +3 more

Structure of DNMT3B homo-oligomer reveals vulnerability to impairment by ICF mutations

Nature Communications(2022)10.1038/s41467-022-31933-w

N/A

0DataRank · unranked

21 citations

Yiran Guo, Mahamaya Biswal, Jiuwei Lu, Jiekai Yin, Jian Fang +7 more

Modulation of the high-order chromatin structure by Polycomb complexes

Frontiers in Cell and Developmental Biology(2022)10.3389/fcell.2022.1021658

N/A

0DataRank · unranked

16 citations

Gang Greg Wang, Yiran Guo

Ribosomal protein RPL11 haploinsufficiency causes anemia in mice via activation of the RP-MDM2-p53 pathway

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102739

N/A

0DataRank · unranked

12 citations

Shijie Liu, Aiwen Jin, Pengfei Cui, Zengli Guo, Kyle C. Arend +6 more

Cell type-specific chromatin topology and gene regulation

Trends in Genetics(2022)10.1016/j.tig.2022.02.008

N/A

0DataRank · unranked

5 citations

Gang Greg Wang, Douglas H. Phanstiel

A cryptic transactivation domain of EZH2 binds AR and AR’s splice variant promoting oncogene activation and tumorous transformation

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.04.502794

N/A

0DataRank · unranked

5 citations

Kwang‐Su Park, Xufen Yu, Weida Gong, H. Shelton Earp, Gang Greg Wang +3 more

Targeted degradation of PRC1 components, BMI1 and RING1B, via a novel protein complex degrader strategy

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.19.517138

N/A

0DataRank · unranked

2 citations

Lihuai Qin, Md Kabir, Kaixiu Luo, Brandon Dale, Yue Zhong +5 more

TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons

Nature(2023)10.1038/s41586-023-06688-z

N/A

0DataRank · unranked

69 citations

Jiuwei Lu, Bo Pan, Huitao Fan, Stephanie D. Byrum, Chenxi Xu +18 more

Discovery of a Potent and Selective Targeted NSD2 Degrader for the Reduction of H3K36me2

Journal of the American Chemical Society(2023)10.1021/jacs.3c01421

N/A

0DataRank · unranked

64 citations

David Y. Nie, John R. Tabor, Fengling Li, Amin Sobh, Chenxi Xu +14 more

Discovery of Potent and Selective WDR5 Proteolysis Targeting Chimeras as Potential Therapeutics for Pancreatic Cancer

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.3c01521

N/A

0DataRank · unranked

51 citations

Dongxu Li, Jithesh Kottur, Huen Suk Kim, Laura E. Herring, Yao Yu +9 more

Targeted Degradation of PRC1 Components, BMI1 and RING1B, via a Novel Protein Complex Degrader Strategy

Advanced Science(2023)10.1002/advs.202205573

N/A

0DataRank · unranked

28 citations

Lihuai Qin, Md Kabir, Kaixiu Luo, Brandon Dale, Yue Zhong +5 more

Onco-condensates: formation, multi-component organization, and biological functions

Trends in cancer(2023)10.1016/j.trecan.2023.05.006

N/A

0DataRank · unranked

27 citations

Arum Kim, Joshua M. Corbin, Gang Greg Wang, Chenxi Xu

Dissecting and targeting noncanonical functions of EZH2 in multiple myeloma via an EZH2 degrader

Oncogene(2023)10.1038/s41388-023-02618-5

N/A

0DataRank · unranked

26 citations

Jun Wang, Weida Gong, Anqi Ma, Yudao Shen, Chengwei Zhang +6 more

An EZH2-NF-κB regulatory axis drives expression of pro-oncogenic gene signatures in triple negative breast cancer

iScience(2023)10.1016/j.isci.2023.107115

N/A

0DataRank · unranked

24 citations

Jun Wang, Jeremy M. Simon, Gang Greg Wang, Albert S. Baldwin, Gabrielle Dardis

Structure-guided functional suppression of AML-associated DNMT3A hotspot mutations

Nature Communications(2024)10.1038/s41467-024-47398-y

N/A

0DataRank · unranked

17 citations

Yiran Guo, Jiekai Yin, Jianbin Chen, Yinsheng Wang, Gang Greg Wang +2 more

TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons

UNC Libraries(2024)10.17615/cd08-n795

N/A

0DataRank · unranked

0 citations

Arum Kim, Nathaniel T. Burkholder, Krishna Kanchi, Yiran Guo, Jikui Song +18 more

Ribosomal protein RPL11 haploinsufficiency causes anemia in mice via activation of the RP-MDM2-p53 pathway

UNC Libraries(2024)10.17615/qxtm-f803

N/A

0DataRank · unranked

0 citations

Shijie Liu, Zengli Guo, Nathaniel J. Moorman, Yanping Zhang, Pengfei Cui +6 more

An EZH2-NF-κB regulatory axis drives expression of pro-oncogenic gene signatures in triple negative breast cancer

UNC Libraries(2024)10.17615/vrqh-4z70

N/A

0DataRank · unranked

0 citations

Jun Wang, Gang Greg Wang, Albert S. Baldwin, Jeremy M. Simon, Gabrielle J Dardis

Biomolecular condensation of human IDRs initiates endogenous transcription via intrachromosomal looping or high-density promoter localization

Nucleic Acids Research(2025)10.1093/nar/gkaf056

N/A

0DataRank · unranked

6 citations

Shizhe Liu, Sung Hwan Kim, Jacob Goell, Zachary Drum, John Patrick Flores +15 more

BAHCC1 binds H4K20me1 to facilitate the MCM complex loading and DNA replication

Nature Communications(2025)10.1038/s41467-025-61284-1

N/A

0DataRank · unranked

3 citations

Zhimin Zhang, Mei Liu, Yu Yao, Yiran Guo, Samuel G. Mackintosh +12 more

Multiple transactivation domains of EZH2 bind to the TAZ2 domain of p300 and stimulate the acetyltransferase function of p300

Biochemical Journal(2025)10.1042/bcj20253037

N/A

0DataRank · unranked

1 citations

Soumi Biswas, Chenxi Xu, Hongwen Xuan, Moustafa Khalil, Ling Cai +7 more

Stress-induced loss of CTCF reveals an alternative, promoter-based mode of cohesin looping

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.64898/2025.12.19.695003

N/A

0DataRank · unranked

1 citations

Andrea A. Perreault, Zachary Drum, Chenxi Xu, Doris Cruz Alonso, Gelila Petros +9 more

YY1 relieves p300 autoinhibition to promote histone acetylation in advanced prostate cancer, enhancing the oncogenic signaling of Androgen Receptor Splice Variant 7

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.04.668477

N/A

0DataRank · unranked

0 citations

Dongyu Wu, Bo Pan, Xiaoxiao Ren, Samuel G. Mackintosh, Kanishk Jain +9 more

Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms

Nature Communications(2020)10.1038/s41467-020-17109-4

N/A

0DataRank · unranked

197 citations

Max Emperle, Yiran Guo, Sara A. Grimm, Wendan Ren, Sabrina Adam +15 more

Epigenetic priming promotes tyrosine kinase inhibitor resistance and oncogene amplification

Nature Structural & Molecular Biology(2025)10.1038/s41594-025-01685-4

N/A

0DataRank · unranked

0 citations

Eric G. Sun, Rana Gbyli, Jonathan S. D. Radda, Jiuwei Lu, Tyler B Jensen +15 more

Direct readout of heterochromatic H3K9me3 regulates DNMT1-mediated maintenance DNA methylation

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.2009316117

N/A

0DataRank · unranked

116 citations

Huitao Fan, Sara A. Grimm, Yiran Guo, Jae Jin Kim, Jiekai Yin +20 more

No Easy Way Out for EZH2: Its Pleiotropic, Noncanonical Effects on Gene Regulation and Cellular Function

International Journal of Molecular Sciences(2020)10.3390/ijms21249501

N/A

0DataRank · unranked

81 citations

Gang Greg Wang, Jun Wang

An H3K36 Methylation-Engaging Tudor Motif of Polycomb-like Proteins Mediates PRC2 Complex Targeting

UNC Libraries(2020)10.17615/q67p-3n83

N/A

0DataRank · unranked

9 citations

Dinshaw J. Patel, Bowen Xu, Deyou Zheng, Shira Rockowitz, Brian D. Strahl +8 more