Alec A. Desai

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 17 papers. Top paper: “Co-optimization of therapeutic antibody affinity and specificity using machine learning models that generalize to novel mutational space”.

Co-optimization of therapeutic antibody affinity and specificity using machine learning models that generalize to novel mutational space

Nature Communications(2022)10.1038/s41467-022-31457-3

N/A

4.2DataRank · unranked

160 citations

Patrick C. Kinnunen, Jie Huang, Lina Wu, Matthew D. Smith, Tiexin Wang +8 more

Engineered Multivalent Nanobodies Potently and Broadly Neutralize SARS‐CoV‐2 Variants

Advanced Therapeutics(2021)10.1002/adtp.202100099

N/A

1.3DataRank · unranked

44 citations

John S. Schardt, Alec A. Desai, Emily K. Makowski, Matthew D. Smith, Ghasidit Pornnoppadol +5 more

Highly sensitive detection of antibody nonspecific interactions using flow cytometry

mAbs(2021)10.1080/19420862.2021.1951426

N/A

1.1DataRank · unranked

47 citations

Lina Wu, Alec A. Desai, Peter M. Tessier, Emily K. Makowski

Reduction of therapeutic antibody self-association using yeast-display selections and machine learning

mAbs(2022)10.1080/19420862.2022.2146629

N/A

1.0DataRank · unranked

28 citations

Hongwei Chen, Matthew Lambert, Eric M. Bennett, Nicole S. Eschmann, Yulei Zhang +10 more

Rational affinity maturation of anti-amyloid antibodies with high conformational and sequence specificity

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.100508

N/A

0.786DataRank · unranked

34 citations

Matthew D. Smith, Yulei Zhang, Emily K. Makowski, Julia E. Gerson, Edward Ionescu +9 more

Facile generation of biepitopic antibodies with intrinsic agonism for activating receptors in the tumor necrosis factor superfamily

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.11.571146

N/A

0DataRank · unranked

0 citations

John S. Schardt, Namir Khalasawi, Emily L. Yao, Timon S. Lwo, Na-Young Kwon +4 more

Human antibody polyreactivity is governed primarily by the heavy-chain complementarity-determining regions

Cell Reports(2024)10.1016/j.celrep.2024.114801

N/A

0DataRank · unranked

15 citations

Yulei Zhang, Jie Huang, Manali Sawant, Matthew D. Smith, Nandhini Rajagopal +8 more

Development of a pan‐tau multivalent nanobody that binds tau aggregation motifs and recognizes pathological tau aggregates

Biotechnology Progress(2024)10.1002/btpr.3463

N/A

0DataRank · unranked

13 citations

B Y Kang, Felix G. Rivera Moctezuma, Akber T. Shaikh, Kathryn Loeffler, Nemil Bhatt +10 more

Facile generation of biepitopic antibodies with intrinsic agonism for activating tumor necrosis factor receptors

Cell chemical biology(2024)10.1016/j.chembiol.2024.03.010

N/A

0DataRank · unranked

5 citations

John S. Schardt, Namir Khalasawi, Emily L. Yao, Timon S. Lwo, Na-Young Kwon +4 more

Native ion mobility‐mass spectrometry reveals the binding mechanisms of anti‐amyloid therapeutic antibodies

Protein Science(2024)10.1002/pro.5008

N/A

0DataRank · unranked

6 citations

Alec A. Desai, Jennifer M. Zupancic, Matthew D. Smith, Peter M. Tessier, Brandon T. Ruotolo +1 more

Affinity targeting of therapeutic proteins to the bone surface—local delivery of sclerostin–neutralizing antibody enhances efficacy

Journal of Bone and Mineral Research(2024)10.1093/jbmr/zjae050

N/A

0DataRank · unranked

3 citations

W. Benton Swanson, Margaret Durdan, Heather N Livingston, Michaela Dodd, Sachith M. Vidanapathirana +6 more

Directed evolution of potent neutralizing nanobodies against SARS-CoV-2 using CDR-swapping mutagenesis

Cell chemical biology(2021)10.1016/j.chembiol.2021.05.019

N/A

0DataRank · unranked

59 citations

Alec A. Desai, John S. Schardt, Ghasidit Pornnoppadol, Emily K. Makowski, Matthew D. Smith +7 more

Directed evolution of drug-like Aβ conformation-specific antibodies

Frontiers in Immunology(2025)10.3389/fimmu.2025.1655893

N/A

0DataRank · unranked

1 citations

Matthew D. Smith, Jennifer M. Zupancic, Emily K. Makowski, Yulei Zhang, Julia E. Gerson +8 more

Discovery and characterization of high-affinity, potent SARS-CoV-2 neutralizing antibodies via single B cell screening

Scientific Reports(2021)10.1038/s41598-021-99401-x

N/A

0DataRank · unranked

25 citations

Ghasidit Pornnoppadol, Alec A. Desai, Kyung Soo Park, Jennifer M. Zupancic, Emily K. Makowski +8 more

A hybridoma-derived monoclonal antibody with high homology to the aberrant myeloma light chain

PLoS ONE(2021)10.1371/journal.pone.0252558

N/A

0DataRank · unranked

6 citations

Boya Zhang, Alec A. Desai, Anthony Berardi, Henriette A. Remmer, Peter M. Tessier +2 more

Facile isolation of high-affinity nanobodies from synthetic libraries using CDR-swapping mutagenesis

STAR Protocols(2022)10.1016/j.xpro.2021.101101

N/A

0DataRank · unranked

11 citations

Alec A. Desai, Peter M. Tessier, Jennifer M. Zupancic

Flow cytometric isolation of drug-like conformational antibodies specific for amyloid fibrils

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.04.547698

N/A

0DataRank · unranked

5 citations

Jennifer M. Zupancic, Hanna Trzeciakiewicz, Julia E. Gerson, Kelly N. Dubois, Mary E. Skinner +14 more