Peter J. Brown

University of North Carolina at Chapel Hill

Also affiliated with University of Toronto, Structural Genomics Consortium

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

A resource to enable chemical biology and drug discovery of WDR Proteins

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.03.583197

Top 100%

0DataRank

Top 100%0 citations

Fengling Li, Magda Szewczyk, Almagul Seitova, P. Loppnau, Hong Zeng +65 more

Papers

Driven by 48 papers — median percentile 0. Top paper: “Enantioselective Chemical Probe for Chikungunya nsP2 Helicase with Antialphaviral Activity”.

Enantioselective Chemical Probe for Chikungunya nsP2 Helicase with Antialphaviral Activity

ACS Infectious Diseases(2025)10.1021/acsinfecdis.5c00351

N/A

0.292DataRank · unranked

6 citations

Hans J. Oh, John D. Sears, Chun‐Hsing Chen, Anand Vala, Shubin Liu +20 more

CACHE Challenge #2: Targeting the RNA Site of the SARS-CoV-2 Helicase Nsp13

Journal of Chemical Information and Modeling(2025)10.1021/acs.jcim.5c00535

N/A

0.292DataRank · unranked

6 citations

Madhushika Silva, Ayaz Ahmad, Oscar E. A. Arce, Roly J. Armstrong, Cheryl Arrowsmith +105 more

CACHE Challenge #2: Targeting the RNA Site of the SARS-CoV-2 Helicase Nsp13

ChemRxiv(2025)10.26434/chemrxiv-2025-8f0rq-v3

N/A

0.165DataRank · unranked

2 citations

Madhushika Silva, Abd Al‐Aziz A. Abu‐Saleh, Ayaz Ahmad, Jesus Antonio Alvarado-Huayhuaz, Oscar E. A. Arce +104 more

CACHE Challenge #2: Targeting the RNA Site of the SARS-CoV-2 Helicase Nsp13

ChemRxiv(2025)10.26434/chemrxiv-2025-8f0rq

N/A

0.150DataRank · unranked

1 citations

Madhushika Silva, Abd Al‐Aziz A. Abu‐Saleh, Ayaz Ahmad, Jesus Antonio Alvarado-Huayhuaz, Oscar E. A. Arce +104 more

Protein Lysine Methyltransferase G9a Inhibitors: Design, Synthesis, and Structure Activity Relationships of 2,4-Diamino-7-aminoalkoxy-quinazolines.

INDIGO (University of Illinois at Chicago)(2020)10.17615/0ecj-ye88

N/A

0DataRank · unranked

5 citations

C.H. Arrowsmith, Irene Chau, Guillermo Senisterra, Masoud Vedadi, Jian Jin +16 more

An Orally Bioavailable Chemical Probe of the Lysine Methyltransferases EZH2 and EZH1

Figshare(2020)10.17615/q3bp-3c89

N/A

0DataRank · unranked

3 citations

Feng Liu, Masoud Vedadi, Kyle D. Konze, C.H. Arrowsmith, Gang Greg Wang +18 more

Discovery of Small-Molecule Antagonists of the PWWP Domain of NSD2

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.25.398586

N/A

0DataRank · unranked

5 citations

Yanli Liu, Magdalena M. Szewczyk, Naimee Mehta, Fengling Li, David McLeod +14 more

A First-in-class, Highly Selective and Cell-active Allosteric Inhibitor of Protein Arginine Methyltransferase 6 (PRMT6)

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.04.412569

N/A

0DataRank · unranked

1 citations

Fengling Li, Magdalena M. Szewczyk, Levon Halebelian, Irene Chau, Mohammad S. Eram +19 more

Discovery of a Selective, Substrate-Competitive Inhibitor of the Lysine Methyltransferase SETD8

UNC Libraries(2020)10.17615/x53z-fd51

N/A

0DataRank · unranked

0 citations

Jian Jin, Rachel M. Bleich, Anqi Ma, Fengling Li, Stephen V. Frye +1 more

A Potent, Selective and Cell-Active Allosteric Inhibitor of Protein Arginine Methyltransferase 3 (PRMT3)

UNC Libraries(2020)10.17615/s278-v194

N/A

0DataRank · unranked

0 citations

Luo Xiao, Magdalena M. Szewczyk, Masoud Vedadi, Aiping Dong, David Smil +24 more

Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain

UNC Libraries(2020)10.17615/17wc-xm97

N/A

0DataRank · unranked

0 citations

Christopher J. MacNevin, Stephen V. Frye, William P. Janzen, Dalia Barsyte-Lovejoy, Xi‐Ping Huang +19 more

A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

UNC Libraries(2020)10.17615/h6h3-eh02

N/A

0DataRank · unranked

0 citations

Peter A. DiMaggio, Dalia Barsyte-Lovejoy, Sylvie Rival‐Gervier, W. Tempel, Feng Liu +27 more

A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization

Nature Chemical Biology(2021)10.1038/s41589-021-00898-0

N/A

0DataRank · unranked

109 citations

Ronan P. Hanley, Renato Ferreira de Freitas, Abdellah Allali‐Hassani, Mengqi Zhou, Naimee Mehta +35 more

Probing the SAM Binding Site of SARS-CoV-2 Nsp14 In Vitro Using SAM Competitive Inhibitors Guides Developing Selective Bisubstrate Inhibitors

SLAS DISCOVERY(2021)10.1177/24725552211026261

N/A

0DataRank · unranked

89 citations

Matthieu Schapira, Sumera Perveen, Aliakbar Khalili Yazdi, Fengling Li, Irene Chau +15 more

A First-in-Class, Highly Selective and Cell-Active Allosteric Inhibitor of Protein Arginine Methyltransferase 6

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.0c02160

N/A

0DataRank · unranked

27 citations

Fengling Li, Magdalena M. Szewczyk, Levon Halabelian, Irene Chau, Mohammad S. Eram +22 more

Identification of small molecule allosteric modulators of 5,10-methylenetetrahydrofolate reductase (MTHFR) by targeting its unique regulatory domain

Biochimie(2021)10.1016/j.biochi.2021.01.007

N/A

0DataRank · unranked

12 citations

Alexander Holenstein, William R. Foster, Bing Xie, Kevin B. Hicks, Céline Bürer +12 more

Probing the SAM Binding Site of SARS-CoV-2 nsp14 in vitro Using SAM Competitive Inhibitors Guides Developing Selective bi-substrate Inhibitors

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.19.424337

N/A

0DataRank · unranked

11 citations

Matthieu Schapira, Sumera Perveen, Aliakbar Khalili Yazdi, Fengling Li, Irene Chau +15 more

Pharmacological targeting of a PWWP domain demonstrates cooperative control of NSD2 localization

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.05.433782

N/A

0DataRank · unranked

3 citations

Ronan P. Hanley, Renato Ferreira de Freitas, Abdellah Allali‐Hassani, Mengqi Zhou, Naimee Mehta +29 more

Small-molecule ligands of methyl-lysine binding proteins: Optimization of selectivity for L3MBTL3

Figshare(2021)10.17615/x6qe-4112

N/A

0DataRank · unranked

0 citations

Masoud Vedadi, Lindsey A. Ingerman, Robert Lam, Victoria Korboukh, J. Martin Herold +11 more

A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II

Nature Communications(2022)10.1038/s41467-022-33229-5

N/A

0DataRank · unranked

20 citations

Aman Iqbal, Weiguo Li, Zuyao Ni, Yalong Wang, Jurupula Ramprasad +16 more

Reference compounds for characterizing cellular injury in high-content cellular morphology assays

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.12.499781

N/A

0DataRank · unranked

1 citations

Bruce K. Hua, Beth E. Zucconi, Shawn D. Nelson, Shantanu Singh, Anne E. Carpenter +21 more

Discovery of a Potent and Selective Targeted NSD2 Degrader for the Reduction of H3K36me2

Journal of the American Chemical Society(2023)10.1021/jacs.3c01421

N/A

0DataRank · unranked

64 citations

David Y. Nie, John R. Tabor, Fengling Li, Amin Sobh, Chenxi Xu +14 more

Discovery of Nanomolar DCAF1 Small Molecule Ligands

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.2c02132

N/A

0DataRank · unranked

63 citations

Serah Kimani, Brian J. Wilson, Mahmoud Noureldin, Héctor González-Álvarez, Ahmed Mamai +29 more

Reference compounds for characterizing cellular injury in high-content cellular morphology assays

Nature Communications(2023)10.1038/s41467-023-36829-x

N/A

0DataRank · unranked

42 citations

Bruce K. Hua, Beth E. Zucconi, Shawn D. Nelson, Shantanu Singh, Anne E. Carpenter +21 more

Discovery of a Druggable, Cryptic Pocket in SARS-CoV-2 nsp16 Using Allosteric Inhibitors

ACS Infectious Diseases(2023)10.1021/acsinfecdis.3c00203

N/A

0DataRank · unranked

22 citations

Ján Kozic, Fengling Li, Mónica Rosas‐Lemus, G. Minasov, Jiří Rybáček +19 more

Discovery of a First-in-Class Small-Molecule Ligand for WDR91 Using DNA-Encoded Chemical Library Selection Followed by Machine Learning

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.3c01471

N/A

0DataRank · unranked

18 citations

Jin Xu, Jianwen A. Feng, Ashley Hutchinson, Hong Zeng, Pegah Ghiabi +20 more

Discovery and Characterization of a Chemical Probe Targeting the Zinc-Finger Ubiquitin-Binding Domain of HDAC6

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.3c00314

N/A

0DataRank · unranked

10 citations

Ivan Franzoni, Mandeep Mann, Magdalena M. Szewczyk, Bijan Mirabi, Renato Ferreira de Freitas +14 more

Discovery of a first-in-class small molecule ligand for WDR91 using DNA-encoded chemical library selection followed by machine learning

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.21.552681

N/A

0DataRank · unranked

2 citations

Jin Xu, Jianwen A. Feng, Ashley Hutchinson, Hong Zeng, Pegah Ghiabi +19 more

Discovery and characterization of a chemical probe targeting the zinc-finger ubiquitin-binding domain of HDAC6

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.21.525740

N/A

0DataRank · unranked

1 citations

Ivan Franzoni, Mandeep Mann, Magdalena M. Szewczyk, Bijan Mirabi, Dominic D. G. Owens +13 more

Identification of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2409166121

N/A

0DataRank · unranked

31 citations

John D. Sears, Tina M. Leisner, P. Brian Hardy, Anirban Ghoshal, Mohammad Anwar Hossain +24 more

Structure Activity of β-Amidomethyl Vinyl Sulfones as Covalent Inhibitors of Chikungunya nsP2 Cysteine Protease with Antialphavirus Activity

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c01346

N/A

0DataRank · unranked

28 citations

Kesatebrhan Haile Asressu, Mohammad Anwar Hossain, Peter J. Brown, Meganathan Nandakumar, Anand Vala +12 more

A Target Class Ligandability Evaluation of WD40 Repeat-Containing Proteins

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c02010

N/A

0DataRank · unranked

22 citations

Fengling Li, Magda Szewczyk, Almagul Seitova, P. Loppnau, Hong Zeng +67 more

Discovery of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.22.586341

N/A

0DataRank · unranked

7 citations

John D. Sears, Tina M. Leisner, P. Brian Hardy, Anirban Ghoshal, Mohammad Anwar Hossain +20 more

Identification of Inhibitors of Chikungunya virus nsP2 ATPase

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.12.02.625520

N/A

0DataRank · unranked

4 citations

J. E. Scott, Ginger R. Smith, Pegah Ghiabi, Elisa Gibson, P. Loppnau +8 more

Structure Activity of β-Amidomethyl Vinyl Sulfones as Covalent Inhibitors of Chikungunya nsP2 Cysteine Protease with Anti-alphavirus Activity

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.06.12.598722

N/A

0DataRank · unranked

2 citations

Kesatebrhan Haile Asressu, Mohammad Anwar Hossain, Peter J. Brown, Eric M. Merten, John D. Sears +7 more

A resource to enable chemical biology and drug discovery of WDR Proteins

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.03.583197

Top 100%

0DataRank

Top 100%0 citations

Fengling Li, Magda Szewczyk, Almagul Seitova, P. Loppnau, Hong Zeng +65 more

Exploring the Ligandability of 53BP1 Through Fragment-Based Approaches

ChemRxiv(2024)10.26434/chemrxiv-2024-lng9q

N/A

0DataRank · unranked

0 citations

Menachem J. Gunzburg, Caroline A. Foley, Hong Zeng, A. Dong, Peter J. Brown +9 more

Identification of Direct-Acting nsP2 Helicase Inhibitors with Antialphaviral Activity

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.5c00635

N/A

0DataRank · unranked

9 citations

John D. Sears, Kacey M. Talbot, Yuan-Wei Norman Su, Scott Houliston, Mohammad Anwar Hossain +27 more

A covalent chemical probe for Chikungunya nsP2 cysteine protease with antialphaviral activity and proteome-wide selectivity

Scientific Reports(2025)10.1038/s41598-025-91673-x

N/A

0DataRank · unranked

9 citations

Edwin G. Tse, Mohammad Anwar Hossain, Kesatebrhan Haile Asressu, Eric M. Merten, John D. Sears +22 more

Nucleosome context regulates chromatin reader preference

Nucleic Acids Research(2025)10.1093/nar/gkaf1061

N/A

0DataRank · unranked

5 citations

Irina K Popova, Nathan W Hall, Anup Vaidya, James R. Bone, Brandon A. Boone +41 more

Enantioselective protein affinity selection mass spectrometry (E-ASMS)

Nature Communications(2025)10.1038/s41467-025-67403-2

N/A

0DataRank · unranked

1 citations

Jianxian Sun, Shabbir Ahmad, Diwen Yang, Fengling Li, U Hang Chan +34 more

Enantioselective Protein Affinity Selection Mass Spectrometry (E-ASMS)

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.17.633682

N/A

0DataRank · unranked

7 citations

Jianxian Sun, Shabbir Ahmad, Diwen Yang, Fengling Li, U Hang Chan +33 more

Nucleosome context regulates chromatin reader preference

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.29.651129

N/A

0DataRank · unranked

3 citations

Irina K Popova, Nathan W Hall, Anup Vaidya, James R. Bone, Brandon A. Boone +40 more

An Enantioselective Chemical Probe for Chikungunya nsP2 Helicase with Antialphaviral Activity

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.24.650479

N/A

0DataRank · unranked

1 citations

Hans J. Oh, John D. Sears, Chun‐Hsing Chen, Anand Vala, Shubin Liu +20 more

Discovery of a First-in-Class Small-Molecule Ligand for WDR91 Using DNA-Encoded Chemical Library Selection Followed by Machine Learning

UNC Libraries(2025)10.17615/d4ft-pp53

N/A

0DataRank · unranked

0 citations

John W. Cuozzo, Peter J. Brown, Jianwen A. Feng, Pegah Ghiabi, Ashley Hutchinson +20 more

Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response

Nature Communications(2020)10.1038/s41467-020-16271-z

N/A

0DataRank · unranked

108 citations

Yoshinori Ishikawa, Shawna Organ, Nozomu Sakai, Fengling Li, Levon Halabelian +26 more

Discovery of a First-in-Class Protein Arginine Methyltransferase 6 (PRMT6) Covalent Inhibitor

Journal of Medicinal Chemistry(2020)10.1021/acs.jmedchem.0c00406

N/A

0DataRank · unranked

42 citations

Fengling Li, Magdalena M. Szewczyk, Levon Halabelian, Kwang‐Su Park, Irene Chau +11 more

Optimization of Cellular Activity of G9a Inhibitors 7-Aminoalkoxy-quinazolines

Figshare(2020)10.17615/66q8-7d37

N/A

0DataRank · unranked

5 citations

Masoud Vedadi, Peter J. Brown, Jian Jin, Stephen V. Frye, Abdellah Allali‐Hassani +8 more

Peter J. Brown

Indexed papers

Top data-sharing exemplar

Papers