Creg J. Workman

Also affiliated with UPMC Hillman Cancer Center, University of Pittsburgh Medical Center

Immunology and MicrobiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 33 papers. Top paper: “People critically ill with COVID-19 exhibit peripheral immune profiles predictive of mortality and reflective of SARS-CoV-2 lung viral burden”.

People critically ill with COVID-19 exhibit peripheral immune profiles predictive of mortality and reflective of SARS-CoV-2 lung viral burden

Cell Reports Medicine(2021)10.1016/j.xcrm.2021.100476

N/A

0.457DataRank · unranked

20 citations

Ashwin Somasundaram, Feng Shan, Carly Cardello, Creg J. Workman, Georgios D. Kitsios +24 more

Neuropilin-1 is a T cell memory checkpoint limiting long-term antitumor immunity

Nature Immunology(2020)10.1038/s41590-020-0733-2

N/A

0DataRank · unranked

151 citations

Ashwin Somasundaram, Sasikanth Manne, Angela M. Gocher, Andrea L. Szymczak-Workman, Kate M. Vignali +9 more

Neuropilin-1: a checkpoint target with unique implications for cancer immunology and immunotherapy

Journal for ImmunoTherapy of Cancer(2020)10.1136/jitc-2020-000967

N/A

0DataRank · unranked

146 citations

Chang Liu, Tullia C. Bruno, Creg J. Workman, Dario A.A. Vignali, Christopher A Chuckran

Competition for Active TGFβ Cytokine Allows for Selective Retention of Antigen-Specific Tissue- Resident Memory T Cells in the Epidermal Niche

Immunity(2020)10.1016/j.immuni.2020.10.022

N/A

0DataRank · unranked

120 citations

Yi Yang, Yukari Zenke, Haiyue Li, Virendra K. Chaudhri, Jacinto S. De La Cruz Diaz +10 more

Resistance to PD1 blockade in the absence of metalloprotease-mediated LAG3 shedding

Science Immunology(2020)10.1126/sciimmunol.abc2728

N/A

0DataRank · unranked

86 citations

Ashwin Somasundaram, Jessica Moskovitz, Andrea L. Szymczak-Workman, Chang Liu, Anthony R. Cillo +12 more

Regulatory T Cells: Barriers of Immune Infiltration Into the Tumor Microenvironment

Frontiers in Immunology(2021)10.3389/fimmu.2021.702726

N/A

0DataRank · unranked

189 citations

Angela M. Gocher, Creg J. Workman, Dario A.A. Vignali, Ellen Scott

Intractable Coronavirus Disease 2019 (COVID-19) and Prolonged Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Replication in a Chimeric Antigen Receptor-Modified T-Cell Therapy Recipient: A Case Study

Clinical Infectious Diseases(2021)10.1093/cid/ciab072

N/A

0DataRank · unranked

140 citations

William Bain, Jana L. Jacobs, Sham Nambulli, Urvi M. Parikh, Anthony R. Cillo +28 more

The costimulatory activity of Tim-3 requires Akt and MAPK signaling and its recruitment to the immune synapse

Science Signaling(2021)10.1126/scisignal.aba0717

N/A

0DataRank · unranked

53 citations

Priyanka Manandhar, Judong Lee, Creg J. Workman, Hridesh Banerjee, Andrea L. Szymczak-Workman +4 more

A Cre-driven allele-conditioning line to interrogate CD4+ conventional T cells

Immunity(2021)10.1016/j.immuni.2021.08.029

N/A

0DataRank · unranked

20 citations

Kate M. Vignali, Andrea L. Szymczak-Workman, Amanda R. Burton, Erin A. Brunazzi, Shin Foong Ngiow +7 more

Regulatory T Cell–Derived TRAIL Is Not Required for Peripheral Tolerance

ImmunoHorizons(2021)10.4049/immunohorizons.2000098

N/A

0DataRank · unranked

6 citations

Stephanie Grebinoski, Qianxia Zhang, Erin A. Brunazzi, Amanda R. Burton, Creg J. Workman +2 more

Bifurcated monocyte states are predictive of mortality in severe COVID-19

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.10.430499

N/A

0DataRank · unranked

9 citations

Ashwin Somasundaram, Feng Shan, Carly Cardello, Creg J. Workman, Georgios D. Kitsios +24 more

Therapeutic targeting of regulatory T cells in cancer

Trends in cancer(2022)10.1016/j.trecan.2022.06.008

N/A

0DataRank · unranked

232 citations

Ashwin Somasundaram, Tullia C. Bruno, Creg J. Workman, Dario A.A. Vignali, Feng Shan

LAG3 associates with TCR–CD3 complexes and suppresses signaling by driving co-receptor–Lck dissociation

Nature Immunology(2022)10.1038/s41590-022-01176-4

N/A

0DataRank · unranked

212 citations

Diana M. Mitrea, Po-Chien Chou, Jamshid Temirov, Kate M. Vignali, Xueyan Liu +7 more

Autoreactive CD8+ T cells are restrained by an exhaustion-like program that is maintained by LAG3

Nature Immunology(2022)10.1038/s41590-022-01210-5

N/A

0DataRank · unranked

108 citations

Qianxia Zhang, Anthony R. Cillo, Sasikanth Manne, Hanxi Xiao, Erin A. Brunazzi +10 more

Systemic Immune Dysfunction in Cancer Patients Driven by IL6 Induction of LAG3 in Peripheral CD8+ T Cells

Cancer Immunology Research(2022)10.1158/2326-6066.cir-20-0736

N/A

0DataRank · unranked

30 citations

Anthony R. Cillo, Caleb Lampenfeld, Creg J. Workman, Sheryl Kunning, Lauren Oliveri +14 more

Antibodies targeting conserved non-canonical antigens and endemic coronaviruses associate with favorable outcomes in severe COVID-19

Cell Reports(2022)10.1016/j.celrep.2022.111020

N/A

0DataRank · unranked

21 citations

Syed A. Rahman, Anthony R. Cillo, Godhev Manakkat Vijay, Ashwin Somasundaram, Creg J. Workman +14 more

Epitope Mapping of Therapeutic Antibodies Targeting Human LAG3

The Journal of Immunology(2022)10.4049/jimmunol.2200309

N/A

0DataRank · unranked

11 citations

Arjun K. Mishra, Priyanka Agarwal, Kate M. Vignali, Creg J. Workman, Dario A.A. Vignali +2 more

952 The temporal contribution of interferon-γ in driving T-cell exhaustion and response to immune checkpoint blockade

Regular and Young Investigator Award Abstracts(2022)10.1136/jitc-2022-sitc2022.0952

N/A

0DataRank · unranked

0 citations

Chang Liu, Lawrence P. Andrews, Madhu Malinee, Carly Cardello, Creg J. Workman +2 more

LAG-3 as the third checkpoint inhibitor

Nature Immunology(2023)10.1038/s41590-023-01569-z

N/A

0DataRank · unranked

330 citations

Creg J. Workman, Dario A.A. Vignali, Vaishali Aggarwal

IFNγ-induction of TH1-like regulatory T cells controls antiviral responses

Nature Immunology(2023)10.1038/s41590-023-01453-w

N/A

0DataRank · unranked

60 citations

Jian Cui, Andrea L. Szymczak-Workman, Kate M. Vignali, Julianna Latini, Gwen P. Pieklo +11 more

Integrated BATF transcriptional network regulates suppressive intratumoral regulatory T cells

Science Immunology(2023)10.1126/sciimmunol.adf6717

N/A

0DataRank · unranked

33 citations

Anthony R. Cillo, Carly Cardello, Daniel Y. Yuan, Sheryl Kunning, Jian Cui +12 more

Pathological Tau transmission initiated by binding lymphocyte-activation gene 3

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.16.541015

N/A

0DataRank · unranked

7 citations

Ramhari Kumbhar, Hu Wang, Xiuli Yang, Kundlik Gadhave, Cyrus Rastegar +20 more

LAG-3 and PD-1 synergize on CD8+ T cells to drive T cell exhaustion and hinder autocrine IFN-γ-dependent anti-tumor immunity

Cell(2024)10.1016/j.cell.2024.07.016

N/A

0DataRank · unranked

244 citations

Samuel C. Butler, Jian Cui, Anthony R. Cillo, Carly Cardello, Chang Liu +15 more

Blockade of LAG-3 and PD-1 leads to co-expression of cytotoxic and exhaustion gene modules in CD8+ T cells to promote antitumor immunity

Cell(2024)10.1016/j.cell.2024.06.036

N/A

0DataRank · unranked

157 citations

Carly Cardello, Feng Shan, Lilit Karapetyan, Sheryl Kunning, Cindy Sander +9 more

Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein

Nature Communications(2024)10.1038/s41467-024-49016-3

N/A

0DataRank · unranked

40 citations

Hao Gu, Donghoon Kim, Yasuyoshi Kimura, Ning Wang, Enquan Xu +37 more

Advances in LAG3 cancer immunotherapeutics

Trends in cancer(2024)10.1016/j.trecan.2024.10.009

N/A

0DataRank · unranked

24 citations

Samuel C. Butler, Creg J. Workman, Dario A.A. Vignali, Kieran Adam

Lymphocyte‐Activation Gene 3 Facilitates Pathological Tau Neuron‐to‐Neuron Transmission

Advanced Science(2024)10.1002/advs.202303775

N/A

0DataRank · unranked

13 citations

Ramhari Kumbhar, Hu Wang, Xiuli Yang, Kundlik Gadhave, Cyrus Rastegar +25 more

Regulatory T Cell Insufficiency in Autoimmune Diabetes Is Driven by Selective Loss of Neuropilin-1 on Intraislet Regulatory T Cells

The Journal of Immunology(2024)10.4049/jimmunol.2300216

N/A

0DataRank · unranked

11 citations

Gwenyth Pieklo, Qianxia Zhang, Anabelle Visperas, Jian Cui, J. R. Goulet +8 more

Ebi3 Binding to IFN-γ and IL-10 Limits Their Function

The Journal of Immunology(2024)10.4049/jimmunol.2400236

N/A

0DataRank · unranked

7 citations

Ye Cheng, Hiroshi Yano, Zhanna Lipatova, Erin A. Brunazzi, Kate M. Vignali +3 more

Ligand-induced ubiquitination unleashes LAG3 immune checkpoint function by hindering membrane sequestration of signaling motifs

Cell(2025)10.1016/j.cell.2025.02.014

N/A

0DataRank · unranked

63 citations

Anran Dai, Yuwei Huang, Hua Li, Jian Cui, Haochen Yang +27 more

Regulatory T cells in the tumor microenvironment display a unique chromatin accessibility profile

ImmunoHorizons(2025)10.1093/immhor/vlae014

N/A

0DataRank · unranked

2 citations

Jian Cui, Dhivyaa Rajasundaram, Hiroshi Yano, Chang Liu, Jonathan Cohen +5 more

Treg-Cell-Derived IL-35-Coated Extracellular Vesicles Promote Infectious Tolerance

Cell Reports(2020)10.1016/j.celrep.2019.12.081

N/A

0DataRank · unranked

161 citations

Yusuke Tomita, Ewa Jankowska−Gan, Diego Lema, Matt Arvedson, Ashita Nair +12 more

Neuronal LAG3 facilitates pathogenic α-synuclein neuron-to-neuron propagation

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.03.631221

N/A

0DataRank · unranked

7 citations

Deok Jeong, Graziella Madeo, Ramhari Kumbhar, Ning Wang, Lili Niu +13 more