P. Jeffrey Conn

Also affiliated with Vanderbilt University, Center for Discovery

NeuroscienceBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 31 papers. Top paper: “Pharmacology and physiology of metabotropic glutamate receptors in mammalian central nervous system”.

Pharmacology and physiology of metabotropic glutamate receptors in mammalian central nervous system

Drug Development Research(1991)10.1002/ddr.430240303

N/A

0.584DataRank · unranked

48 citations

Manisha A. Desai, P. Jeffrey Conn

mGlu1 potentiation enhances prelimbic somatostatin interneuron activity to rescue schizophrenia-like physiological and cognitive deficits

Cell Reports(2021)10.1016/j.celrep.2021.109950

N/A

0.561DataRank · unranked

41 citations

Nellie Byun, Deborah J. Luessen, Brianna Li, Robert Barry, John C. Gore +5 more

A GRM7 mutation associated with developmental delay reduces mGlu7 expression and produces neurological phenotypes

JCI Insight(2021)10.1172/jci.insight.143324

N/A

0.520DataRank · unranked

31 citations

Aqeela AlHashim, Aditi Buch, Hana Badivuku, Manar Samman, Kelly Weiss +8 more

Discovery of VU0467319: an M1 Positive Allosteric Modulator Candidate That Advanced into Clinical Trials

ACS Chemical Neuroscience(2024)10.1021/acschemneuro.4c00769

N/A

0.457DataRank · unranked

11 citations

Michael R. Wood, Changho Han, Shaun R. Stauffer, Joseph D. Panarese, Bruce J. Melancon +21 more

Frontal cortex genetic ablation of metabotropic glutamate receptor subtype 3 (mGlu3) impairs postsynaptic plasticity and modulates affective behaviors

Neuropsychopharmacology(2021)10.1038/s41386-021-01041-2

N/A

0.385DataRank · unranked

12 citations

Chiaki I. Santiago, Sheryl Anne D. Vermudez, Nicole M. Fisher, Shalini Dogra, Colleen M. Niswender +2 more

Synthesis and pharmacological evaluation of bivalent tethered ligands to target the mGlu2/4 heterodimeric receptor results in a compound with mGlu2/2 homodimer selectivity

Bioorganic & Medicinal Chemistry Letters(2020)10.1016/j.bmcl.2020.127212

N/A

0.330DataRank · unranked

8 citations

Matthew T. Loch, Alice L. Rodriguez, Xin Lin, Jonathan A. Javitch, P. Jeffrey Conn +3 more

Modeling intrahippocampal effects of anterior hippocampal hyperactivity relevant to schizophrenia using chemogenetic excitation of long axis-projecting mossy cells in the mouse dentate gyrus

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.15.422938

N/A

0DataRank · unranked

0 citations

Sarah L. Rader, Max E. Joffe, Wooseok Kwon, Juliana Quay, Leann Seanez +4 more

Targeting muscarinic receptors to treat schizophrenia

Behavioural Brain Research(2021)10.1016/j.bbr.2021.113201

N/A

0DataRank · unranked

95 citations

Zoey Bryant, P. Jeffrey Conn, Daniel J. Foster

Targeting metabotropic glutamate receptors for the treatment of depression and other stress-related disorders

Neuropharmacology(2021)10.1016/j.neuropharm.2021.108687

N/A

0DataRank · unranked

72 citations

P. Jeffrey Conn, Shalini Dogra

Activating mGlu3 Metabotropic Glutamate Receptors Rescues Schizophrenia-like Cognitive Deficits Through Metaplastic Adaptations Within the Hippocampus

Biological Psychiatry(2021)10.1016/j.biopsych.2021.02.970

N/A

0DataRank · unranked

47 citations

Branden J. Stansley, Zixiu Xiang, Weilun Qian, Rocco G. Gogliotti, Ferdinando Nicoletti +5 more

Activating mGlu 3 metabotropic glutamate receptors rescues schizophrenia-like cognitive deficits through metaplastic adaptations within the hippocampus

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.27.356196

N/A

0DataRank · unranked

1 citations

Branden J. Stansley, Zixiu Xiang, Weilun Qian, Rocco G. Gogliotti, Ferdinando Nicoletti +5 more

Discovery of the first selective M 4 muscarinic acetylcholine receptor antagonists with in vivo anti-parkinsonian and anti-dystonic efficacy

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.12.324152

N/A

0DataRank · unranked

1 citations

Aaron M. Bender, Jonathan W. Dickerson, Daniel J. Foster, Yuping Donsante, Weimin Peng +14 more

Profiling beneficial and potential adverse effects of MeCP2 overexpression in a hypomorphic Rett syndrome mouse model

Genes Brain & Behavior(2021)10.1111/gbb.12752

N/A

0DataRank · unranked

14 citations

Rocco G. Gogliotti, Bright Arthur, Aditi Buch, Clarissa Morales, Yuta Moxley +4 more

Modeling Intrahippocampal Effects of Anterior Hippocampal Hyperactivity Relevant to Schizophrenia Using Chemogenetic Excitation of Long Axis–Projecting Mossy Cells in the Mouse Dentate Gyrus

Biological Psychiatry Global Open Science(2021)10.1016/j.bpsgos.2021.04.005

N/A

0DataRank · unranked

16 citations

Sarah L. Rader, Max E. Joffe, Wooseok Kwon, Juliana Quay, Leann Seanez +4 more

Discovery of structurally distinct tricyclic M4 positive allosteric modulator (PAM) chemotypes – Part 2

Bioorganic & Medicinal Chemistry Letters(2021)10.1016/j.bmcl.2021.128416

N/A

0DataRank · unranked

8 citations

Rory A. Capstick, Paul K. Spearing, Julie L. Engers, Alison R. Gregro, Sean R. Bollinger +11 more

Contrasting sex-dependent adaptations to synaptic physiology and membrane properties of prefrontal cortex interneuron subtypes in a mouse model of binge drinking

Neuropharmacology(2020)10.1016/j.neuropharm.2020.108126

N/A

0DataRank · unranked

62 citations

Danny G. Winder, P. Jeffrey Conn, Max E. Joffe

Allosteric Modulators of Metabotropic Glutamate Receptors as Novel Therapeutics for Neuropsychiatric Disease

Pharmacological Reviews(2022)10.1124/pharmrev.121.000540

N/A

0DataRank · unranked

36 citations

P. Jeffrey Conn, Deborah J. Luessen

Prefrontal cortex parvalbumin interneurons exhibit decreased excitability and potentiated synaptic strength after ethanol reward learning

Alcohol(2022)10.1016/j.alcohol.2022.02.003

N/A

0DataRank · unranked

23 citations

Kari A. Johnson, Danny G. Winder, P. Jeffrey Conn, Max E. Joffe, Anthony S. Ferranti

Development of VU6019650: A Potent, Highly Selective, and Systemically Active Orthosteric Antagonist of the M5 Muscarinic Acetylcholine Receptor for the Treatment of Opioid Use Disorder

Journal of Medicinal Chemistry(2022)10.1021/acs.jmedchem.2c00192

N/A

0DataRank · unranked

23 citations

Douglas L. Orsi, Rory A. Capstick, David Whomble, Jinming Li, Trever R. Carter +21 more

Metabotropic glutamate receptor 3 as a potential therapeutic target for psychiatric and neurological disorders

Pharmacology Biochemistry and Behavior(2022)10.1016/j.pbb.2022.173493

N/A

0DataRank · unranked

16 citations

Jason Putnam, P. Jeffrey Conn, Shalini Dogra

Activation of group II metabotropic glutamate (mGlu2/3) receptors regulates excitatory synaptic plasticity in the nucleus accumbens: Implications for the treatment of schizophrenia

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r6041

N/A

0DataRank · unranked

0 citations

P. Jeffrey Conn, Shalini Dogra

D1 and D2 medium spiny neurons in the nucleus accumbens core have distinct and valence-independent roles in learning

Neuron(2023)10.1016/j.neuron.2023.11.023

N/A

0DataRank · unranked

77 citations

Munir Gunes Kutlu, Hye Jean Yoon, Michael Z. Leonard, Maxime Chevée, Dev Patel +13 more

Activation of Metabotropic Glutamate Receptor 3 Modulates Thalamo-accumbal Transmission and Rescues Schizophrenia-Like Physiological and Behavioral Deficits

Biological Psychiatry(2023)10.1016/j.biopsych.2023.11.023

N/A

0DataRank · unranked

3 citations

Caleb Aguayo, Zixiu Xiang, Jason Putnam, J. R. Smith, Curran Johnston +5 more

Discovery of VU6007496: Challenges in the Development of an M1 Positive Allosteric Modulator Backup Candidate

ACS Chemical Neuroscience(2024)10.1021/acschemneuro.4c00508

N/A

0DataRank · unranked

8 citations

Katrina A. Bollinger, Rory A. Capstick, Madeline F. Long, Aaron M. Bender, Jonathan W. Dickerson +14 more

Discovery of VU6008677: A Structurally Distinct Tricyclic M4 Positive Allosteric Modulator with Improved CYP450 Profile

ACS Medicinal Chemistry Letters(2024)10.1021/acsmedchemlett.4c00249

N/A

0DataRank · unranked

6 citations

Sean R. Bollinger, Julie L. Engers, Madeline F. Long, Sichen Chang, Vincent B. Luscombe +9 more

Discovery of VU6024578/BI02982816: An mGlu1 Positive Allosteric Modulator with Efficacy in Preclinical Antipsychotic and Cognition Models

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c02554

N/A

0DataRank · unranked

3 citations

Jacob F. Kalbfleisch, Jeremy A. Turkett, Trevor A. Trombley, Anthony F. Nastase, Paul K. Spearing +17 more

Discovery of Thieno[3,2-b]pyridine-5-carboxamide and 2,3-Difluorobenzamide Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5

ACS Medicinal Chemistry Letters(2025)10.1021/acsmedchemlett.5c00119

N/A

0DataRank · unranked

2 citations

Scott H. Henderson, Rory A. Capstick, David Whomble, Aaron M. Bender, Andrew S. Felts +18 more

Further Optimization of the mGlu1 PAM VU6024578/BI02982816: Discovery and Characterization of VU6033685

ACS Chemical Neuroscience(2025)10.1021/acschemneuro.5c00014

N/A

0DataRank · unranked

0 citations

Jacob F. Kalbfleisch, Jeremy A. Turkett, Trevor A. Trombley, Paul K. Spearing, Daniel H. Haymer +16 more

Discovery of VU6052254: A Novel, Potent M 1 Positive Allosteric Modulator

ACS Chemical Neuroscience(2025)10.1021/acschemneuro.5c00825

N/A

0DataRank · unranked

0 citations

Joseph D. Bungard, Christopher C. Presley, Irène Zagol-Ikapitte, Katherine J. Watson, Sichen Chang +15 more

Contrasting adaptations to synaptic physiology of prefrontal cortex interneuron subtypes in a mouse model of binge drinking

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.05.895169

N/A

0DataRank · unranked

0 citations

Danny G. Winder, P. Jeffrey Conn, Max E. Joffe

Modulation of arousal and sleep/wake architecture by M1 PAM VU0453595 across young and aged rodents and nonhuman primates

Neuropsychopharmacology(2020)10.1038/s41386-020-00812-7

N/A

0DataRank · unranked

20 citations

Jason K Russell, Michael T. Nedelcovych, Michael Bubser, Anna L. Blobaum, Thomas M. Bridges +6 more