Gary L. Johnson

University of North Carolina at Chapel Hill

Also affiliated with UNC Lineberger Comprehensive Cancer Center

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

7.4Author DataRank

Indexed papers

3in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 3 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Analysis of Orthologous Gene Expression between Human Pulmonary Adenocarcinoma and a Carcinogen-Induced Murine Model

The American Journal of Pathology(2005)10.1016/s0002-9440(10)61257-6

Top 2%

7.4DataRank

Top 2%314 citations

Lori Dwyer-Nield, Laura Zerbe, Stacy A. Blaine, Zeng Chan, Paul A. Bunn +14 more

Papers

Driven by 79 papers — median percentile 0. Top paper: “Analysis of Orthologous Gene Expression between Human Pulmonary Adenocarcinoma and a Carcinogen-Induced Murine Model”.

Analysis of Orthologous Gene Expression between Human Pulmonary Adenocarcinoma and a Carcinogen-Induced Murine Model

The American Journal of Pathology(2005)10.1016/s0002-9440(10)61257-6

Top 2%

7.4DataRank

Top 2%314 citations

Lori Dwyer-Nield, Laura Zerbe, Stacy A. Blaine, Zeng Chan, Paul A. Bunn +14 more

Receptor activation of G proteins

The FASEB Journal(1988)10.1096/fasebj.2.13.3139484

N/A

4.7DataRank · unranked

85 citations

Daniel J. Kelleher, Chee Wai Woon, Sidhartha Soparkar, Shoji Osawa, Lynn E. Heasley +2 more

Cabozantinib for neurofibromatosis type 1–related plexiform neurofibromas: a phase 2 trial

Nature Medicine(2021)10.1038/s41591-020-01193-6

N/A

2.0DataRank · unranked

96 citations

Chie‐Schin Shih, Steven D. Rhodes, Amy E. Armstrong, Pamela L. Wolters, Eva Dombi +25 more

Limited inhibition of multiple nodes in a driver network blocks metastasis

eLife(2021)10.7554/elife.59696

N/A

0.964DataRank · unranked

35 citations

Dongbo Yang, Andrea Valdespino, Payal Tiwari, Alan U. Sabino, Long C. Nguyen +13 more

The NH2‐terminal α subunit attenuator domain confers regulation of G protein activation by βγ complexes

Journal of Cellular Biochemistry(1991)10.1002/jcb.240470409

N/A

0.563DataRank · unranked

8 citations

Shoji Osawa, Gary L. Johnson, N. Dhanasekaran

Supplementary Figures from Mass Spectrometry–Based Proteomics Reveals Potential Roles of NEK9 and MAP2K4 in Resistance to PI3K Inhibition in Triple-Negative Breast Cancers

(2023)10.1158/0008-5472.22416134

N/A

0DataRank · unranked

0 citations

Sandeep Rajput, Shunqiang Li, Kelly V. Ruggles, Arshag D. Mooradian, Philipp Mertins +28 more

Supplementary File 1 from Mass Spectrometry–Based Proteomics Reveals Potential Roles of NEK9 and MAP2K4 in Resistance to PI3K Inhibition in Triple-Negative Breast Cancers

INDIGO (University of Illinois at Chicago)(2023)10.1158/0008-5472.22416131.v1

N/A

0DataRank · unranked

0 citations

Sandeep Rajput, Shunqiang Li, Kelly V. Ruggles, Arshag D. Mooradian, Philipp Mertins +28 more

Supplementary File 5 from Mass Spectrometry–Based Proteomics Reveals Potential Roles of NEK9 and MAP2K4 in Resistance to PI3K Inhibition in Triple-Negative Breast Cancers

(2023)10.1158/0008-5472.22416119

N/A

0DataRank · unranked

0 citations

Sandeep Rajput, Shunqiang Li, Kelly V. Ruggles, Arshag D. Mooradian, Philipp Mertins +28 more

Supplementary tables 1 and 2 from Mass Spectrometry–Based Proteomics Reveals Potential Roles of NEK9 and MAP2K4 in Resistance to PI3K Inhibition in Triple-Negative Breast Cancers

INDIGO (University of Illinois at Chicago)(2023)10.1158/0008-5472.22416116.v1

Top 100%

0DataRank

Top 100%0 citations

Sandeep Rajput, Shunqiang Li, Kelly V. Ruggles, Arshag D. Mooradian, Philipp Mertins +28 more

Data from Mass Spectrometry–Based Proteomics Reveals Potential Roles of NEK9 and MAP2K4 in Resistance to PI3K Inhibition in Triple-Negative Breast Cancers

(2023)10.1158/0008-5472.c.6509465

N/A

0DataRank · unranked

0 citations

Sandeep Rajput, Shunqiang Li, Kelly V. Ruggles, Arshag D. Mooradian, Philipp Mertins +28 more

Extended Methods from Mass Spectrometry–Based Proteomics Reveals Potential Roles of NEK9 and MAP2K4 in Resistance to PI3K Inhibition in Triple-Negative Breast Cancers

(2023)10.1158/0008-5472.22416140

N/A

0DataRank · unranked

0 citations

Sandeep Rajput, Shunqiang Li, Kelly V. Ruggles, Arshag D. Mooradian, Philipp Mertins +28 more

Supplementary File 2 from Mass Spectrometry–Based Proteomics Reveals Potential Roles of NEK9 and MAP2K4 in Resistance to PI3K Inhibition in Triple-Negative Breast Cancers

(2023)10.1158/0008-5472.22416128

N/A

0DataRank · unranked

0 citations

Sandeep Rajput, Shunqiang Li, Kelly V. Ruggles, Arshag D. Mooradian, Philipp Mertins +28 more

Supplementary File 4 from Mass Spectrometry–Based Proteomics Reveals Potential Roles of NEK9 and MAP2K4 in Resistance to PI3K Inhibition in Triple-Negative Breast Cancers

INDIGO (University of Illinois at Chicago)(2023)10.1158/0008-5472.22416122.v1

N/A

0DataRank · unranked

0 citations

Sandeep Rajput, Shunqiang Li, Kelly V. Ruggles, Arshag D. Mooradian, Philipp Mertins +28 more

Extended Methods from Mass Spectrometry–Based Proteomics Reveals Potential Roles of NEK9 and MAP2K4 in Resistance to PI3K Inhibition in Triple-Negative Breast Cancers

INDIGO (University of Illinois at Chicago)(2023)10.1158/0008-5472.22416140.v1

N/A

0DataRank · unranked

0 citations

Sandeep Rajput, Shunqiang Li, Kelly V. Ruggles, Arshag D. Mooradian, Philipp Mertins +28 more

Supplementary Figures from Mass Spectrometry–Based Proteomics Reveals Potential Roles of NEK9 and MAP2K4 in Resistance to PI3K Inhibition in Triple-Negative Breast Cancers

INDIGO (University of Illinois at Chicago)(2023)10.1158/0008-5472.22416134.v1

N/A

0DataRank · unranked

0 citations

Sandeep Rajput, Shunqiang Li, Kelly V. Ruggles, Arshag D. Mooradian, Philipp Mertins +28 more

Nf1 -Mutant Tumors Undergo Transcriptome and Kinome Remodeling after Inhibition of either mTOR or MEK

Molecular Cancer Therapeutics(2020)10.1158/1535-7163.mct-19-1017

N/A

0DataRank · unranked

6 citations

Steven P. Angus, Benjamin J. Huang, Chi Zhang, Hiroki J. Nakaoka, Ganesh Krishnamurthi +6 more

Discrete Adaptive Responses to MEK Inhibitor in Subpopulations of Triple-Negative Breast Cancer

Molecular Cancer Research(2020)10.1158/1541-7786.mcr-19-1011

N/A

0DataRank · unranked

9 citations

Joseph P. Foster, Jon S. Zawistowski, Samantha M. Bevill, Mélodie P. Noël, José F. Olivares-Quintero +7 more

Inhibition of Lapatinib-Induced Kinome Reprogramming in ERBB2-Positive Breast Cancer by Targeting BET Family Bromodomains

UNC Libraries(2020)10.17615/vnt3-7a98

N/A

0DataRank · unranked

3 citations

Jon S. Zawistowski, Lisa A. Carey, Rachel A. Reuther, Kazuhiro Nakamura, Steven P. Angus +15 more

Tracking the intermediate stages of epithelial-mesenchymal transition in epithelial stem cells and cancer

UNC Libraries(2020)10.17615/2dgt-7318

N/A

0DataRank · unranked

2 citations

Amy N. Abell, Nicole Vincent Jordan, Gary L. Johnson

UNC569, a Novel Small-Molecule Mer Inhibitor with Efficacy against Acute Lymphoblastic Leukemia In Vitro and In Vivo

UNC Libraries(2020)10.17615/4pj9-cy35

N/A

0DataRank · unranked

3 citations

Sandra Christoph, Dmitri Kireev, Emily A. Hull-Ryde, Chao Yang, Deborah DeRyckere +16 more

Efficiently identifying genome-wide changes with next-generation sequencing data

UNC Libraries(2020)10.17615/zj9w-fv15

N/A

0DataRank · unranked

3 citations

Nicole Vincent Jordan, Gary L. Johnson, Amy N. Abell, Leping Li, David M. Umbach +1 more

Dynamic Reprogramming of the Kinome in Response to Targeted MEK Inhibition in Triple-Negative Breast Cancer

UNC Libraries(2020)10.17615/ebx5-w380

N/A

0DataRank · unranked

1 citations

Deborah A. Granger, Jon S. Zawistowski, David B. Darr, Alicia A. Midland, Jerry Usary +22 more

Combined PI3K/mTOR and MEK Inhibition Provides Broad Antitumor Activity in Faithful Murine Cancer Models

UNC Libraries(2020)10.17615/n3y7-sa69

N/A

0DataRank · unranked

0 citations

Jian Jin, Søren M. Johnson, Patrick M. Dillon, Austin J. Combest, David B. Darr +9 more

PB1 Domain Interaction of p62/Sequestosome 1 and MEKK3 Regulates NF-κB Activation

UNC Libraries(2020)10.17615/nngg-g171

N/A

0DataRank · unranked

0 citations

David P. Siderovski, Gary L. Johnson, Kazuhiro Nakamura, Adam J. Kimple

Defining the Functional Domain of Programmed Cell Death 10 through Its Interactions with Phosphatidylinositol-3,4,5-Trisphosphate

UNC Libraries(2020)10.17615/ak3d-af68

N/A

0DataRank · unranked

0 citations

Brenda Temple, Sompop Bencharit, Holly Cheeseman, Justin R. Barbaro, Jeremy A. Horst +4 more

The Role of MEKK1 in Hypertrophic Cardiomyopathy

UNC Libraries(2020)10.17615/jwnr-ss02

N/A

0DataRank · unranked

0 citations

Dana Boucek, Gary L. Johnson, Todd R. Horn, John P. Konhilas, Leslie A. Leinwand

Molecular Pathways: Adaptive Kinome Reprogramming in Response to Targeted Inhibition of the BRAF-MEK-ERK Pathway in Cancer

UNC Libraries(2020)10.17615/cx2z-ty05

N/A

0DataRank · unranked

0 citations

Steven P. Angus, Gary L. Johnson, Jon S. Zawistowski, Lee M. Graves, Timothy J. Stuhlmiller

MAP3K4 Controls the Chromatin Modifier HDAC6 during Trophoblast Stem Cell Epithelial-to-Mesenchymal Transition

UNC Libraries(2020)10.17615/kxrt-6272

N/A

0DataRank · unranked

0 citations

Sujoy Roy, Amy N. Abell, Jon S. Zawistowski, Kayley Abell-Hart, Robert J. Mobley +6 more

MAP3K4/CBP-Regulated H2B Acetylation Controls Epithelial-Mesenchymal Transition in Trophoblast Stem Cells

UNC Libraries(2020)10.17615/awxx-pc97

N/A

0DataRank · unranked

0 citations

Leping Li, Piotr A. Mieczkowski, Weichun Huang, Aleix Prat, Alicia A. Midland +7 more

Kinome and Transcriptome Profiling Reveal Broad and Distinct Activities of Erlotinib, Sunitinib, and Sorafenib in the Mouse Heart and Suggest Cardiotoxicity From Combined Signal Transducer and Activator of Transcription and Epidermal Growth Factor Receptor Inhibition

UNC Libraries(2020)10.17615/x5w4-8c48

N/A

0DataRank · unranked

0 citations

Wei Huang, Brian C. Jensen, Ju Youn Beak, Timothy J. Stuhlmiller, Xin Chen +7 more

Rho Kinase Inhibition Rescues the Endothelial Cell Cerebral Cavernous Malformation Phenotype

UNC Libraries(2020)10.17615/c7e9-mq69

N/A

0DataRank · unranked

0 citations

Amy N. Abell, Sompop Bencharit, Gary L. Johnson, Asya L. Borikova, Christopher M. Welch +2 more

Development and Validation of a High-Throughput Intrinsic ATPase Activity Assay for the Discovery of MEKK2 Inhibitors

UNC Libraries(2020)10.17615/a58s-em90

N/A

0DataRank · unranked

0 citations

Mark Hughes, Syed A. Ahmad, J. E. Scott, Gary L. Johnson

Crizotinib inhibits NF2-associated schwannoma through inhibition of focal adhesion kinase 1

UNC Libraries(2020)10.17615/76hc-t002

N/A

0DataRank · unranked

0 citations

Gary L. Johnson, Scott Troutman, K.W. Nettles, Smitha Kota, Joseph L. Kissil +2 more

An Unbiased Proteomic Screen Reveals Caspase Cleavage Is Positively and Negatively Regulated by Substrate Phosphorylation

UNC Libraries(2020)10.17615/xyag-1203

N/A

0DataRank · unranked

0 citations

Shawn S.‐C. Li, Lee M. Graves, Stephanie A. Zukowski, Gilles Lajoie, James D.R. Knight +4 more

The dynamic nature of the kinome

UNC Libraries(2020)10.17615/6bjg-5d28

N/A

0DataRank · unranked

0 citations

James S. Duncan, Martin C. Whittle, Gary L. Johnson, Lee M. Graves

Identification of ponatinib and other known kinase inhibitors with potent MEKK2 inhibitory activity

UNC Libraries(2020)10.17615/mz5e-y796

N/A

0DataRank · unranked

0 citations

Syed A. Ahmad, J. E. Scott, Gary L. Johnson

Coordination of Rho GTPase activities during cell protrusion

UNC Libraries(2020)10.17615/3a4c-w564

N/A

0DataRank · unranked

0 citations

Amy N. Abell, Christopher J. Welch, Klaus M. Hahn, Matthias Macháček, Hunter Elliott +5 more

Application of Multiplexed Kinase Inhibitor Beads to Study Kinome Adaptations in Drug-Resistant Leukemia

UNC Libraries(2020)10.17615/5gg8-3m30

N/A

0DataRank · unranked

0 citations

Nathan J. Cox, Stephen V. Frye, Gary L. Johnson, David M. Smalley, Martin C. Whittle +13 more

Kinome Profiling Identifies Druggable Targets for Novel Human Cytomegalovirus (HCMV) Antivirals

UNC Libraries(2020)10.17615/4en3-d531

N/A

0DataRank · unranked

0 citations

Laura E. Herring, Heather A. Vincent, Kyle C. Arend, Ian M. McDonald, Thomas S.K. Gilbert +7 more

Loss of Arp2/3 induces an NF-κB–dependent, nonautonomous effect on chemotactic signaling

UNC Libraries(2020)10.17615/n796-qd81

N/A

0DataRank · unranked

0 citations

James E. Bear, Gary L. Johnson, Jeremy M. Simon, Sreeja B. Asokan, Norman E. Sharpless +4 more

Cerebral cavernous malformation is a vascular disease associated with activated RhoA signaling

UNC Libraries(2020)10.17615/97qf-9n45

N/A

0DataRank · unranked

0 citations

Bryan Richardson, Asya L. Borikova, Christopher F. Dibblel, Gary L. Johnson

New strategies for targeting kinase networks in cancer

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.101128

N/A

0DataRank · unranked

56 citations

Gary L. Johnson, Alexandre F. Ramos, Marsha Rich Rosner, Ali E. Yesilkanal

SOX4 and SMARCA4 cooperatively regulate PI3k signaling through transcriptional activation of TGFBR2

npj Breast Cancer(2021)10.1038/s41523-021-00248-2

N/A

0DataRank · unranked

26 citations

Steven P. Angus, Christen A. Khella, Kevin Tong, Pooja Khanna, Shelley A.H. Dixon +4 more

PRM-LIVE with Trapped Ion Mobility Spectrometry and Its Application in Selectivity Profiling of Kinase Inhibitors

Analytical Chemistry(2021)10.1021/acs.analchem.1c02349

N/A

0DataRank · unranked

30 citations

Scott B. Ficarro, William M. Alexander, Laura E. Fleming, Guillaume Adelmant, Tinghu Zhang +10 more

FOXA1 and adaptive response determinants to HER2 targeted therapy in TBCRC 036

npj Breast Cancer(2021)10.1038/s41523-021-00258-0

N/A

0DataRank · unranked

24 citations

Timothy J. Stuhlmiller, Gaurav Mehta, Samantha M. Bevill, Daniel R. Goulet, José F. Olivares-Quintero +25 more

Adaptive chromatin remodeling and transcriptional changes of the functional kinome in tumor cells in response to targeted kinase inhibition

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.101525

N/A

0DataRank · unranked

22 citations

Gary L. Johnson, Michael P. East

Synthesis and Evaluation of Novel 1,2,6-Thiadiazinone Kinase Inhibitors as Potent Inhibitors of Solid Tumors

Molecules(2021)10.3390/molecules26195911

N/A

0DataRank · unranked

5 citations

Michael P. East, Tuomo Laitinen, Chad Torrice, Kaitlyn Maffuid, David H. Drewry +5 more

PB1 Domains of MEKK2 and MEKK3 Interact with the MEK5 PB1 Domain for Activation of the ERK5 Pathway

UNC Libraries(2021)10.17615/cz48-ja72

N/A

0DataRank · unranked

5 citations

Gary L. Johnson, Kazuhiro Nakamura

MEKK4 Is an Effector of the Embryonic TRAF4 for JNK Activation

UNC Libraries(2021)10.17615/8zva-5e68

N/A

0DataRank · unranked

0 citations

Amy N. Abell, Gary L. Johnson

Small-molecule inhibition of the archetypal UbiB protein COQ8

Nature Chemical Biology(2022)10.1038/s41589-022-01168-3

N/A

0DataRank · unranked

10 citations

Christopher R. M. Asquith, Zixiang Fang, Michael P. East, Naomi Ptak, Robert Smith +8 more

Identification of 4‐Anilinoquin(az)oline as a Cell‐Active Protein Kinase Novel 3 (PKN3) Inhibitor Chemotype**

ChemMedChem(2022)10.1002/cmdc.202200161

N/A

0DataRank · unranked

3 citations

Louisa Temme, Michael P. East, Tuomo Laitinen, Julie E. Pickett, Frank E. Kwarcinski +6 more

Numb-associated kinases are required for SARS-CoV-2 infection and are cellular targets for therapy

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.18.484178

N/A

0DataRank · unranked

1 citations

Sirle Saul, Luca Ghita, Malaya K. Sahoo, Chengjin Ye, Nishank Bhalla +12 more

Combined CDK4/6 and ERK1/2 Inhibition Enhances Antitumor Activity in NF1-Associated Plexiform Neurofibroma

Clinical Cancer Research(2023)10.1158/1078-0432.ccr-22-2854

N/A

0DataRank · unranked

16 citations

Dana K. Mitchell, Steven P. Angus, Abbi E. Smith, Waylan Bessler, Li Jiang +19 more

Combined kinome inhibition states are predictive of cancer cell line sensitivity to kinase inhibitor combination therapies

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.01.551346

N/A

0DataRank · unranked

1 citations

Kevin A. Chen, Samantha Beville, Timothy J. Stuhlmiller, Matthew E. Berginski, Denis O. Okumu +4 more

Discovery and Optimization of Narrow Spectrum Inhibitors of Tousled Like Kinase 2 (TLK2) Using Quantitative Structure Activity Relationships

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.28.573261

N/A

0DataRank · unranked

1 citations

Michael P. East, Tuomo Laitinen, Carla Alamillo‐Ferrer, Erkka Hartikainen, Carrow I. Wells +7 more

Combined kinome inhibition states are predictive of cancer cell line sensitivity to kinase inhibitor combination therapies

PubMed(2023)10.1142/9789811286421_0022

N/A

0DataRank · unranked

0 citations

Kevin A. Chen, Samantha Beville, Timothy J. Stuhlmiller, Matthew E. Berginski, Denis O. Okumu +5 more

Illuminating function of the understudied druggable kinome

Drug Discovery Today(2024)10.1016/j.drudis.2024.103881

N/A

0DataRank · unranked

17 citations

Alison D. Axtman, Timothy M. Willson, Michael B. Major, Reid Townsend, Peter K. Sorger +2 more

Phase II study of MEK inhibitor trametinib alone and in combination with AKT inhibitor GSK2141795/uprosertib in patients with metastatic triple negative breast cancer

Breast Cancer Research and Treatment(2024)10.1007/s10549-024-07551-z

N/A

0DataRank · unranked

12 citations

H. Boutrid, Mahmoud Kassem, Mahmoud Abdel‐Rasoul, Cynthia Timmers, Maryam B. Lustberg +19 more

Tumor-Intrinsic Kinome Landscape of Pancreatic Cancer Reveals New Therapeutic Approaches

Cancer Discovery(2024)10.1158/2159-8290.cd-23-1480

N/A

0DataRank · unranked

5 citations

Xianlu Laura Peng, Michael P. East, Ian C. McCabe, Grace C. Stroman, Madison R. Jenner +16 more

Discovery and optimization of narrow spectrum inhibitors of Tousled like kinase 2 (TLK2) using quantitative structure activity relationships

European Journal of Medicinal Chemistry(2024)10.1016/j.ejmech.2024.116357

N/A

0DataRank · unranked

3 citations

Michael P. East, Tuomo Laitinen, Carla Alamillo‐Ferrer, Erkka Hartikainen, Carrow I. Wells +7 more

Kinome state is predictive of cell viability in pancreatic cancer tumor and cancer-associated fibroblast cell lines

PeerJ(2024)10.7717/peerj.17797

N/A

0DataRank · unranked

3 citations

Madison R. Jenner, Chinmaya U. Joisa, Gabriela Herrera Loeza, Brian T. Golitz, Matthew B. Lipner +6 more

PIP4K2C inhibition reverses autophagic flux impairment induced by SARS-CoV-2

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.15.589676

N/A

0DataRank · unranked

2 citations

Manjari Mishra, Chieh‐Wen Lo, Sirle Saul, H. Busra Cagirici, Do Hoang Nhu Tran +22 more

Quantitative proteomic mass spectrometry of protein kinases to determine dynamic heterogeneity of the human kinome

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.10.04.614143

N/A

0DataRank · unranked

2 citations

Robert W. Sprung, Denis O. Okumu, José F. Olivares-Quintero, Chinmaya U. Joisa, Xin Chen +21 more

Kinase Plasticity with Vandetanib Treatment Enhances Sensitivity to Tamoxifen in Estrogen Receptor Positive Breast Cancer

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.12.19.629395

N/A

0DataRank · unranked

2 citations

Rasha T. Kakati, Santiago Haase, Christine Thai, Attila Szénási, Elizabeth Brunk +10 more

Correction: Combined CDK4/6 and ERK1/2 Inhibition Enhances Antitumor Activity in NF1-Associated Plexiform Neurofibroma

Clinical Cancer Research(2024)10.1158/1078-0432.ccr-24-0635

N/A

0DataRank · unranked

0 citations

Dana K. Mitchell, Steven P. Angus, Abbi E. Smith, Waylan Bessler, Li Jiang +19 more

Irreversible JNK1-JUN inhibition by JNK-IN-8 sensitizes pancreatic cancer to 5-FU/FOLFOX chemotherapy

UNC Libraries(2024)10.17615/76z2-h138

N/A

0DataRank · unranked

0 citations

Silvia G. Herrera Loeza, Yi Xu, Richard A. Moffitt, Chong Jin, Ashley B. Morrison +10 more

Application of Integrated Drug Screening/Kinome Analysis to Identify Inhibitors of Gemcitabine-Resistant Pancreatic Cancer Cell Growth

UNC Libraries(2024)10.17615/jadh-1012

N/A

0DataRank · unranked

0 citations

Laura E. Herring, Alison D. Axtman, Michael P. East, Benjamin Lee, Denis O. Okumu +12 more

Intra-tumoral hypoxia promotes CD8+ T cell dysfunction via chronic activation of integrated stress response transcription factor ATF4

Immunity(2025)10.1016/j.immuni.2025.09.003

N/A

0DataRank · unranked

33 citations

Brian Riesenberg, Evelyn J. Gandy, Andrew S. Kennedy, Genevieve Clutton, Jessica Hem +19 more

PIP4K2C inhibition reverses autophagic flux impairment induced by SARS-CoV-2

Nature Communications(2025)10.1038/s41467-025-61759-1

N/A

0DataRank · unranked

10 citations

Manjari Mishra, Chieh‐Wen Lo, Sirle Saul, H. Busra Cagirici, Manon Gourdelier +29 more

Kinome Reprogramming of G2/M Kinases and Repression of MYCN Contribute to Superior Efficacy of Lorlatinib in ALK-Driven Neuroblastoma

Molecular Cancer Therapeutics(2025)10.1158/1535-7163.mct-24-0684

N/A

0DataRank · unranked

4 citations

Michael P. East, Timothy J. Stuhlmiller, Gabriela M. Witek, Alvin Farrel, Steven Pastor +13 more

Combined kinome inhibition states are predictive of cancer cell line sensitivity to kinase inhibitor combination therapies.

UNC Libraries(2025)10.17615/tg7c-sn11

N/A

0DataRank · unranked

0 citations

Shawn M. Gomez, Gary L. Johnson, Chinmaya U. Joisa, Kevin A. Chen, Samantha Beville +5 more

Kinome reprogramming of G2/M kinases and repression of MYCN contribute to superior efficacy of lorlatinib in ALK-driven neuroblastoma.

UNC Libraries(2025)10.17615/pbz0-mn14

N/A

0DataRank · unranked

0 citations

Mark Gerelus, Michael P. East, Alvin Farrel, Steven Pastor, John M. Maris +13 more

Combined CDK4/6 and ERK1/2 Inhibition Enhances Antitumor Activity in NF1-Associated Plexiform Neurofibroma.

UNC Libraries(2025)10.17615/y9hc-s085

N/A

0DataRank · unranked

0 citations

D. Wade Clapp, George E. Sandusky, Gregory P. Donoho, Steven P. Angus, Andrea R. Masters +19 more

Supplementary File 5 from Mass Spectrometry–Based Proteomics Reveals Potential Roles of NEK9 and MAP2K4 in Resistance to PI3K Inhibition in Triple-Negative Breast Cancers

INDIGO (University of Illinois at Chicago)(2023)10.1158/0008-5472.22416119.v1

N/A

0DataRank · unranked

0 citations

Sandeep Rajput, Shunqiang Li, Kelly V. Ruggles, Arshag D. Mooradian, Philipp Mertins +28 more

Kinome state is predictive of cell viability in pancreatic cancer tumor and cancer-associated fibroblast cell lines.

UNC Libraries(2025)10.17615/zk43-2w75

N/A

0DataRank · unranked

0 citations

Brian T. Golitz, Madison R. Jenner, Chinmaya U. Joisa, Naim Rashid, Jen Jen Yeh +6 more

Supplementary File 2 from Mass Spectrometry–Based Proteomics Reveals Potential Roles of NEK9 and MAP2K4 in Resistance to PI3K Inhibition in Triple-Negative Breast Cancers

INDIGO (University of Illinois at Chicago)(2023)10.1158/0008-5472.22416128.v1

N/A

0DataRank · unranked

0 citations

Sandeep Rajput, Shunqiang Li, Kelly V. Ruggles, Arshag D. Mooradian, Philipp Mertins +28 more

Supplementary File 4 from Mass Spectrometry–Based Proteomics Reveals Potential Roles of NEK9 and MAP2K4 in Resistance to PI3K Inhibition in Triple-Negative Breast Cancers

(2023)10.1158/0008-5472.22416122

N/A

0DataRank · unranked

0 citations

Sandeep Rajput, Shunqiang Li, Kelly V. Ruggles, Arshag D. Mooradian, Philipp Mertins +28 more

Supplementary tables 1 and 2 from Mass Spectrometry–Based Proteomics Reveals Potential Roles of NEK9 and MAP2K4 in Resistance to PI3K Inhibition in Triple-Negative Breast Cancers

(2023)10.1158/0008-5472.22416116

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Sandeep Rajput, Shunqiang Li, Kelly V. Ruggles, Arshag D. Mooradian, Philipp Mertins +28 more

Data from Mass Spectrometry–Based Proteomics Reveals Potential Roles of NEK9 and MAP2K4 in Resistance to PI3K Inhibition in Triple-Negative Breast Cancers

(2023)10.1158/0008-5472.c.6509465.v1

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Sandeep Rajput, Shunqiang Li, Kelly V. Ruggles, Arshag D. Mooradian, Philipp Mertins +28 more

Gary L. Johnson

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