Robyn T. Rebbeck

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 34 papers. Top paper: “The functional significance of redox-mediated intersubunit cross-linking in regulation of human type 2 ryanodine receptor”.

The functional significance of redox-mediated intersubunit cross-linking in regulation of human type 2 ryanodine receptor

Redox Biology(2020)10.1016/j.redox.2020.101729

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0DataRank · unranked

15 citations

Elisa Bovo, Robyn T. Rebbeck, Daniel Kahn, David D. Thomas, Rǎzvan L. Cornea +2 more

Novel drug discovery platform for spinocerebellar ataxia, using fluorescence technology targeting β-III-spectrin

Journal of Biological Chemistry(2020)10.1074/jbc.ra120.015417

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11 citations

Anna Andrick, Sarah A. Denha, Bengt Svensson, Piyali Guhathakurta, David D. Thomas +3 more

Mechanical factors tune the sensitivity of mdx muscle to eccentric strength loss and its protection by antioxidant and calcium modulators

Skeletal Muscle(2020)10.1186/s13395-020-0221-2

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44 citations

Cory W. Baumann, Robyn T. Rebbeck, Samantha L. Yuen, William M. Southern, James S. Hodges +5 more

RyR1-targeted drug discovery pipeline integrating FRET-based high-throughput screening and human myofiber dynamic Ca2+ assays

Scientific Reports(2020)10.1038/s41598-020-58461-1

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37 citations

Daniel P. Singh, Kevyn A. Janicek, Donald M. Bers, David D. Thomas, Bradley S. Launikonis +2 more

Met125 is essential for maintaining the structural integrity of calmodulin’s C-terminal domain

Scientific Reports(2020)10.1038/s41598-020-78270-w

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2 citations

Daniel K. Weber, Robyn T. Rebbeck, Rǎzvan L. Cornea, Gianluigi Veglia, David D. Thomas +1 more

High-Throughput Screening Yields Allosteric Inhibitors of Leaky RyRs for Therapeutic Development

Biophysical Journal(2020)10.1016/j.bpj.2019.11.3095

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0 citations

Gabrielle M. Evans, Kaja Rožman, Jacob Schwarz, Michael C. Wold, Marzena Baran +5 more

CaMKIIδ post-translational modifications increase affinity for calmodulin inside cardiac ventricular myocytes

Journal of Molecular and Cellular Cardiology(2021)10.1016/j.yjmcc.2021.08.002

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14 citations

Christopher Y. Ko, Robyn T. Rebbeck, Sonya Baidar, Rǎzvan L. Cornea, Donald M. Bers +1 more

Identification of a dihydropyridine scaffold that blocks ryanodine receptors

iScience(2021)10.1016/j.isci.2021.103706

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3 citations

Robyn T. Rebbeck, Lindsey M. McGurran, Yasheng Yan, Thiago Arzua, Talia Frolkis +6 more

Cardiac RyR N-terminal region biosensors for FRET-based high-throughput screening

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.07.430153

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0 citations

Siobhan M. Wong King Yuen, Jacob Schwarz, Levy M. Treinen, Ching‐Chieh Tung, Robyn T. Rebbeck +7 more

High-Throughput Screening and Drug Development to Fix RyR Pathology

Biophysical Journal(2021)10.1016/j.bpj.2020.11.1089

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0 citations

Kaja Rožman, Gabrielle M. Evans, Jacob Schwarz, Marzena Baran, Courtney C. Aldrich +4 more

FRET-based trilateration resolves distinct structural states and transitions of calmodulin bound to ryanodine receptors

Biophysical Journal(2022)10.1016/j.bpj.2021.11.864

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0 citations

Robyn T. Rebbeck, Jingyan Zhang, Donald M. Bers, David D. Thomas, Rǎzvan L. Cornea +1 more

FRET assays for RyR-targeted drug discovery platforms

Biophysical Journal(2022)10.1016/j.bpj.2021.11.1857

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0 citations

Kaja Berg, Gabrielle M. Evans, Jacob Schwarz, Jake R. Trask, Lindsey M. McGurran +5 more

Identification of β-III-spectrin actin-binding modulators for treatment of spinocerebellar ataxia

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.08.515660

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0 citations

Robyn T. Rebbeck, Sarah A. Denha, Amanda R. Keller, Anna L. Carter, Alexandra E. Atang +5 more

Fluorescence lifetime FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulators

Scientific Reports(2023)10.1038/s41598-023-37704-x

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18 citations

Samantha L. Yuen, Andrew R. Thompson, Lauren N. Roelike, Robyn T. Rebbeck, Philip A. Bidwell +4 more

Regulation of cardiac calcium signaling by newly identified calcium pump modulators

Biochemical and Biophysical Research Communications(2023)10.1016/j.bbrc.2023.149136

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7 citations

Robyn T. Rebbeck, Osha Roopnarine, Rǎzvan L. Cornea, David D. Thomas, Aleksey V. Zima +1 more

Early-phase drug discovery of β-III-spectrin actin-binding modulators for treatment of spinocerebellar ataxia type 5

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.102956

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7 citations

Robyn T. Rebbeck, Sarah A. Denha, Amanda R. Keller, Anna L. Carter, Alexandra E. Atang +5 more

RyR2 Binding of an Antiarrhythmic Cyclic Depsipeptide Mapped Using Confocal Fluorescence Lifetime Detection of FRET

ACS Chemical Biology(2023)10.1021/acschembio.3c00376

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6 citations

Jacob Schwarz, Abigail N. Smith, Bengt Svensson, Daniel J. Blackwell, Taylor A. Phillips +11 more

Indirubin Inhibits TRAIL-Induced Activation of Death Receptor 5 in Jurkat Cells

Natural Product Communications(2023)10.1177/1934578x221144580

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4 citations

Nagamani Vunnam, Robyn T. Rebbeck, Samantha L. Yuen, David D. Thomas, Jonathan N. Sachs +1 more

Molecular Mechanism of a FRET Biosensor for the Cardiac Ryanodine Receptor Pathologically Leaky State

International Journal of Molecular Sciences(2023)10.3390/ijms241612547

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4 citations

Florentin R. Nitu, Robyn T. Rebbeck, Lindsey M. McGurran, Tetsuro Oda, David D. Thomas +3 more

Molecular Mechanism of a FRET Biosensor for the Cardiac Ryanodine Receptor Pathologically Leaky State

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.07.548138

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1 citations

Florentin R. Nitu, Robyn T. Rebbeck, Lindsey M. McGurran, Tetsuro Oda, David D. Thomas +3 more

FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulators

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.22.529557

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0DataRank · unranked

0 citations

Samantha L. Yuen, Andrew R. Thompson, Lauren N. Roelike, Robyn T. Rebbeck, Philip A. Bidwell +4 more

FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulators

Research Square(2023)10.21203/rs.3.rs-2596384/v1

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0 citations

Samantha L. Yuen, Andrew R. Thompson, Lauren N. Roelike, Robyn T. Rebbeck, Phillip A. Bidwell +4 more

RyR2 Binding of an Antiarrhythmic Cyclic Depsipeptide Mapped Using Confocal Fluorescence Lifetime Detection of FRET

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.22.546083

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0DataRank · unranked

0 citations

Jacob Schwarz, Abigail N. Smith, Bengt Svensson, Daniel J. Blackwell, Taylor A. Phillips +11 more

Kinetics and mapping of Ca-driven calmodulin conformations on skeletal and cardiac muscle ryanodine receptors

Nature Communications(2024)10.1038/s41467-024-48951-5

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7 citations

Bengt Svensson, Jingyan Zhang, Montserrat Samsó, David D. Thomas, Donald M. Bers +2 more

Small-molecule allosteric modulators of SERCA2a for pharmaceutical therapy of heart failure

Biophysical Journal(2024)10.1016/j.bpj.2023.11.2087

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0 citations

Samantha L. Yuen, Elisa Bovo, Marzena Baran, Andrew R. Thompson, Robyn T. Rebbeck +4 more

Calcium channel-targeted modulators identified by FRET-based high-throughput screening

Biophysical Journal(2024)10.1016/j.bpj.2023.11.2777

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0 citations

Benjamin D. Van Setters, Marzena Brinkmann, Andrew R. Thompson, Courtney C. Aldrich, Donald M. Bers +3 more

Impaired Atrial Mitochondrial Calcium Handling in Patients With Atrial Fibrillation

Circulation Research(2025)10.1161/circresaha.124.325658

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10 citations

Fleur E. Mason, Eva A. Rog‐Zielinska, Funsho E. Fakuade, Donata Bülow, Marcell Tóth +39 more

Catecholaminergic polymorphic ventricular tachycardia–linked ryanodine receptor variants exhibit domain‐specific calcium leak and calmodulin affinity properties

The Journal of Physiology(2025)10.1113/jp288499

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6 citations

Xiaoqiong Dong, Ivanita Stefanon, Yi Yang, Eduardo Hertel Ribeiro, Bengt Svensson +7 more

Large-scale high-throughput screen for cardiac ryanodine receptor targeted therapeutics

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110951

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1 citations

Elisa Bovo, Jonathan Solberg, Marzena Brinkmann, Levy M. Treinen, Andrew R. Thompson +9 more

BPS2025 - Calcium channel and transporter targeted modulators identified by FRET-based high-throughput screening

Biophysical Journal(2025)10.1016/j.bpj.2024.11.648

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0 citations

Samantha L. Yuen, Michael E. Fealey, Marzena Brinkmann, Benjamin D. Van Setters, Andrew R. Thompson +5 more

BPS2025 - Live-cell FRET biosensors for high-throughput screening targeting the SERCA2a-DWORF complex

Biophysical Journal(2025)10.1016/j.bpj.2024.11.1623

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0 citations

Ingrid Hayden, Samantha L. Yuen, Andrew R. Thompson, Bengt Svensson, Osha Roopnarine +3 more

BPS2025 - SERCA2a-targeted drugs for treatment of heart failure: Medicinal chemistry development of a compound identified via high-throughput screening

Biophysical Journal(2025)10.1016/j.bpj.2024.11.1614

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0 citations

Marzena Brinkmann, Samantha L. Yuen, Tien Yin Wong, Kaja Berg, Rǎzvan L. Cornea +4 more

Introduction of a single carboxylic acid converts the cyclic oligomeric depsipeptide ent-verticilide from a ryanodine receptor 2 (RyR2) inhibitor to RyR2 activator

Molecular Pharmacology(2025)10.1016/j.molpha.2025.100086

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0 citations

Daniel J. Blackwell, Abigail N. Smith, Madelaine P. Thorpe, Robyn T. Rebbeck, Derek R. Laver +3 more

Development of activators for SERCA2a for heart failure treatments

European Journal of Medicinal Chemistry(2025)10.1016/j.ejmech.2025.118408

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0 citations

Tsung-Yun Wong, Osha Roopnarine, Samantha L. Yuen, Kaja Berg, Rǎzvan L. Cornea +4 more