Eric R. Gamazon

Also affiliated with University of Cambridge, University of Chicago, Bridge University, Vanderbilt University Medical Center

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

40.2Author DataRank

Indexed papers

12in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 12 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Genetic effects on gene expression across human tissues

Nature(2017)10.1038/nature24277

Top 1%

10.1DataRank

Top 1%4706 citations

Barbara E. Engelhardt, Stephen B. Montgomery, Sara Mostafavi, Ayellet V. Segrè, Hailei Zhang +227 more

Papers

Driven by 118 papers — median percentile 86. Top paper: “Correction: Corrigendum: Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases”.

Correction: Corrigendum: Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases

Scientific Reports(2016)10.1038/srep19384

N/A

10.4DataRank · unranked

722 citations

Tao Huang, Francesca Petralia, Quan Long, Bin Zhang, Carmen Argmann +129 more

Cell type–specific genetic regulation of gene expression across human tissues

Science(2020)10.1126/science.aaz8528

N/A

10.3DataRank · unranked

596 citations

François Aguet, Meritxell Oliva, Manuel Muñoz-Aguirre, Silva Kasela, Valentin Wucher +77 more

Genetic effects on gene expression across human tissues

Nature(2017)10.1038/nature24277

Top 1%

10.1DataRank

Top 1%4706 citations

Barbara E. Engelhardt, Stephen B. Montgomery, Sara Mostafavi, Ayellet V. Segrè, Hailei Zhang +227 more

The impact of sex on gene expression across human tissues

Science(2020)10.1126/science.aba3066

N/A

9.0DataRank · unranked

727 citations

Manuel Muñoz-Aguirre, Sarah Kim-Hellmuth, Valentin Wucher, Ariel DH Gewirtz, Daniel J. Cotter +72 more

Determinants of telomere length across human tissues

Science(2020)10.1126/science.aaz6876

N/A

8.6DataRank · unranked

501 citations

Farzana Jasmine, Lin Chen, Meytal Chernoff, Tong Lin, Dayana Delgado +90 more

The GTEx Consortium atlas of genetic regulatory effects across human tissues

Science(2020)10.1126/science.aaz1776

Top 2%

8.0DataRank

Top 2%5930 citations

Shankara Anand, Kristin G. Ardlie, Stacey Gabriel, Gad Getz, Aaron Graubert +95 more

Using an atlas of gene regulation across 44 human tissues to inform complex disease- and trait-associated variation

Nature Genetics(2018)10.1038/s41588-018-0154-4

Top 3%

6.3DataRank

Top 3%492 citations

Eric R. Gamazon, Ayellet V. Segrè, Martijn van de Bunt, Xiaoquan Wen, Emilio Rodríguez-Ruiz +14 more

The Genotype-Tissue Expression (GTEx) project

Nature Genetics(2013)10.1038/ng.2653

Top 3%

6.0DataRank

Top 3%10097 citations

Mike Salvatore, Rebecca Phillips, Bernadette Mestichelli, Saboor Shad, Richard Hasz +144 more

A Quantitative Proteome Map of the Human Body

Cell(2020)10.1016/j.cell.2020.08.036

Top 4%

5.1DataRank

Top 4%487 citations

Meng Wang, Shin Lin, Ruiqi Jian, Xiao Li, Joanne Chan +95 more

Transcriptomic signatures across human tissues identify functional rare genetic variation

Science(2020)10.1126/science.aaz5900

N/A

5.0DataRank · unranked

166 citations

Benjamin J. Strober, Jonah Einson, Nathan S. Abell, François Aguet, Alvaro N. Barbeira +183 more

Rare and common genetic determinants of metabolic individuality and their effects on human health

Nature Medicine(2022)10.1038/s41591-022-02046-0

N/A

4.1DataRank · unranked

157 citations

Isobel D. Stewart, Victoria P. W. Au Yeung, Maik Pietzner, Johannes Raffler, Maria A. Wörheide +31 more

Genetic architecture of host proteins involved in SARS-CoV-2 infection

Nature Communications(2020)10.1038/s41467-020-19996-z

N/A

3.4DataRank · unranked

152 citations

Eleanor Wheeler, Julia Carrasco-Zanini, Johannes Raffler, Nicola D. Kerrison, Erin Oerton +13 more

A vast resource of allelic expression data spanning human tissues

Genome Biology(2020)10.1186/s13059-020-02122-z

Top 8%

2.7DataRank

Top 8%147 citations

François Aguet, Pejman Mohammadi, Kristin G. Ardlie, Anthony Philippakis, Leanne Haggerty +159 more

Best practices for multi-ancestry, meta-analytic transcriptome-wide association studies: Lessons from the Global Biobank Meta-analysis Initiative

Cell Genomics(2022)10.1016/j.xgen.2022.100180

N/A

1.1DataRank · unranked

40 citations

Jibril Hirbo, Dan Zhou, Wei Zhou, Jie Zheng, Masahiro Kanai +4 more

The genetic architecture of type 2 diabetes

Nature(2016)10.1038/nature18642

N/A

1.1DataRank · unranked

1106 citations

Menachem Fromer, Tanya M. Teslovich, Anubha Mahajan, Vineeta Agarwala, Kyle J. Gaulton +334 more

Integrative Network-Based Analysis Reveals Gene Networks and Novel Drug Repositioning Candidates for Alzheimer Disease

Neurology Genetics(2021)10.1212/nxg.0000000000000622

Top 21%

0.989DataRank

Top 21%36 citations

Eric R. Gamazon, Anthony R. White, Eske M. Derks, Zachary F. Gerring

Effect of predicted protein-truncating genetic variants on the human transcriptome

Science(2015)10.1126/science.1261877

N/A

0.877DataRank · unranked

345 citations

Matti Pirinen, Donald F. Conrad, Monkol Lek, Emily K. Tsang, Konrad J. Karczewski +206 more

SLC25A39 is necessary for mitochondrial glutathione import in mammalian cells

Nature(2021)10.1038/s41586-021-04025-w

N/A

0.833DataRank · unranked

257 citations

Frederick S. Yen, Xiphias Ge Zhu, Rebecca C. Timson, Ross Weber, Changrui Xing +11 more

Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases

Scientific Reports(2015)10.1038/srep15145

N/A

0.811DataRank · unranked

222 citations

Tao Huang, Francesca Petralia, Quan Long, Bin Zhang, Carmen Argmann +128 more

Population-scale tissue transcriptomics maps long non-coding RNAs to complex disease

Cell(2021)10.1016/j.cell.2021.03.050

N/A

0.804DataRank · unranked

212 citations

Daniel C. Nachun, Nicole M. Ferraro, Michael J. Gloudemans, Abhiram S. Rao, Craig Smail +168 more

Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts

Cell Genomics(2023)10.1016/j.xgen.2022.100241

N/A

0.710DataRank · unranked

113 citations

Shinichi Namba, Esteban A. Lopera-Maya, Sini Kerminen, Kristin Tsuo, Kristi Läll +83 more

Meta-analysis fine-mapping is often miscalibrated at single-variant resolution

Cell Genomics(2022)10.1016/j.xgen.2022.100210

N/A

0.670DataRank · unranked

86 citations

Roy Elzur, Wei Zhou, Kuan-Han Wu, Humaira Rasheed, Kristin Tsuo +91 more

Multi-omic analysis elucidates the genetic basis of hydrocephalus

Cell Reports(2021)10.1016/j.celrep.2021.109085

N/A

0.571DataRank · unranked

44 citations

Lisa Bastarache, Diego M. Morales, John C. Wellons, David D. Limbrick, Eric R. Gamazon +1 more

A Transcriptome-Wide Association Study Identifies Candidate Susceptibility Genes for Pancreatic Cancer Risk

Cancer Research(2020)10.1158/0008-5472.can-20-1353

N/A

0.571DataRank · unranked

44 citations

Dan Zhou, Yanfa Sun, Jingjing Zhu, Dalia Ghoneim, Chong Wu +5 more

Multilayer modelling of the human transcriptome and biological mechanisms of complex diseases and traits

npj Systems Biology and Applications(2021)10.1038/s41540-021-00186-6

Top 35%

0.563DataRank

Top 35%14 citations

Giovanna Maria Dimitri, Píetro Lió, Eric R. Gamazon, Tiago Azevedo

Multiplexed Assays of Variant Effect and Automated Patch Clamping Improve KCNH2 -LQTS Variant Classification and Cardiac Event Risk Stratification

Circulation(2024)10.1161/circulationaha.124.069828

N/A

0.553DataRank · unranked

39 citations

Chai‐Ann Ng, Takanori Aizawa, Luca Sala, Sahej Bains, Annika Winbo +37 more

Genome-wide association studies in women of African ancestry identified 3q26.21 as a novel susceptibility locus for oestrogen receptor negative breast cancer

UNC Libraries(2020)10.17615/45kg-tz48

N/A

0.551DataRank · unranked

9 citations

Oladosu Ojengbede, Jennifer J. Hu, Christine B. Ambrosone, Kathryn L. Lunetta, Stephen A. Haddad +42 more

A transcriptome‐wide association study identifies novel candidate susceptibility genes for prostate cancer risk

International Journal of Cancer(2021)10.1002/ijc.33808

N/A

0.529DataRank · unranked

33 citations

Jingjing Zhu, Dan Zhou, Emily G. Nikas, Nikos T. Mitanis, Yanfa Sun +10 more

A Genome-wide Association Study of Early-Onset Breast Cancer Identifies PFKM as a Novel Breast Cancer Gene and Supports a Common Genetic Spectrum for Breast Cancer at Any Age

UNC Libraries(2021)10.17615/nrx2-ar02

N/A

0.520DataRank · unranked

6 citations

Nancy J. Cox, Maria Argos, Jennifer Stone, Shantanu Roy, Bertram Müller-Myhsok +71 more

Novel ancestry-specific primary open-angle glaucoma loci and shared biology with vascular mechanisms and cell proliferation

Cell Reports Medicine(2024)10.1016/j.xcrm.2024.101430

N/A

0.510DataRank · unranked

29 citations

Arjun Bhattacharya, Wei Zhou, Dan Zhou, Ying Wang, Kristi Läll +31 more

Metabolic gene function discovery platform GeneMAP identifies SLC25A48 as necessary for mitochondrial choline import

Nature Genetics(2024)10.1038/s41588-024-01827-2

N/A

0.500DataRank · unranked

27 citations

Gökhan Ünlü, Phillip Lin, Yuyang Liu, Ece Kılıç, Timothy C. Kenny +3 more

Transcriptome-wide association study and Mendelian randomization in pancreatic cancer identifies susceptibility genes and causal relationships with type 2 diabetes and venous thromboembolism

EBioMedicine(2024)10.1016/j.ebiom.2024.105233

N/A

0.497DataRank · unranked

15 citations

Chelsea A. Isom, Yangzi Liu, David-Alexandre Trégouët, Sara Lindström, Lu Wang +52 more

CD36 maintains the gastric mucosa and associates with gastric disease

Communications Biology(2021)10.1038/s42003-021-02765-z

N/A

0.457DataRank · unranked

20 citations

Zhi‐Feng Miao, Vivek S. Peche, Edward F. Morris, Ramkumar Narendran, Kathryn M. Pietka +11 more

Novel diabetes gene discovery through comprehensive characterization and integrative analysis of longitudinal gene expression changes

Human Molecular Genetics(2022)10.1093/hmg/ddac039

N/A

0.457DataRank · unranked

20 citations

Lauren E. Petty, Kari E. North, Joseph B. McCormick, Susan P. Fisher‐Hoch, Eric R. Gamazon +2 more

A prognostic molecular signature of hepatic steatosis is spatially heterogeneous and dynamic in human liver

Cell Reports Medicine(2024)10.1016/j.xcrm.2024.101871

N/A

0.406DataRank · unranked

14 citations

Niran Hadad, Emeli Chatterjee, Maria Jiménez Ramos, Eric Farber‐Eger, Rashedeh Roshani +38 more

Network reconstruction for trans acting genetic loci using multi-omics data and prior information

Genome Medicine(2022)10.1186/s13073-022-01124-9

N/A

0.269DataRank · unranked

5 citations

Ashis Saha, Melanie Waldenberger, Sonja Kunze, Simone Wahl, Martina Müller-Nurasyid +14 more

Integration of estimated regional gene expression with neuroimaging and clinical phenotypes at biobank scale

PLoS Biology(2024)10.1371/journal.pbio.3002782

Top 59%

0.256DataRank

Top 59%3 citations

Neda Sardaripour, Grace D Ramey, Kurt Schilling, Emily Liao, Yi-Ting Chen +8 more

Genome sequencing of 35,024 predominantly African ancestry persons addresses gaps in genomics and healthcare

medRxiv(2025)10.1101/2025.10.30.25338549

N/A

0.241DataRank · unranked

4 citations

Mojgan Babanejad, James Baker, Xavier Bledsoe, Freida Blostein, Robert W. Corty +26 more

Genomic Variants of Cytarabine Sensitivity Associated with Treatment-Related Mortality in Pediatric AML: A Report from the Children's Oncology Group

Clinical Cancer Research(2020)10.1158/1078-0432.ccr-19-3117

N/A

0.241DataRank · unranked

4 citations

Adam Lane, Robert B. Gerbing, Todd A. Alonzo, Alyss Wilkey, Gretchen A. Radloff +5 more

Genetic analysis in African ancestry populations reveals genetic contributors to lung cancer susceptibility

The American Journal of Human Genetics(2025)10.1016/j.ajhg.2025.07.009

N/A

0.208DataRank · unranked

3 citations

James Jaworski, Shilin Zhao, Jinmeng Rao, Bríd M. Ryan, Ann G. Schwartz +9 more

Mapping dynamic regulation of gene expression using single-cell transcriptomics and application to complex disease genetics

Human Genetics and Genomics Advances(2024)10.1016/j.xhgg.2024.100397

N/A

0.208DataRank · unranked

3 citations

P. Charles Lin, Dan Zhou, Douglas M. Ruderfer, Eric R. Gamazon, Hanna Abe

Microvascular insulin resistance associates with enhanced muscle glucose disposal in CD36 deficiency.

medRxiv(2024)10.1101/2024.02.16.24302950

N/A

0.165DataRank · unranked

2 citations

Vivek S. Peche, Ian M. Williams, Dmitri Samovski, Terri Pietka, Naji N. Abumrad +5 more

Multiancestry transferability of a polygenic risk score for diverticulitis

BMJ Open Gastroenterology(2024)10.1136/bmjgast-2024-001474

N/A

0.165DataRank · unranked

2 citations

Jonathan D. Mosley, Christopher J. Neylan, John P. Shelley, Jamie R. Robinson, Eric R. Gamazon +4 more

Plasma Proteomic Signatures for Diverticulitis Risk Stratification

Journal of Surgical Research(2025)10.1016/j.jss.2025.06.093

N/A

0.165DataRank · unranked

2 citations

John P. Shelley, Jonathan D. Mosley, Jamie R. Robinson, Eric R. Gamazon, Lillias H. Maguire +3 more

Multiplexed Assays of Variant Effect and Automated Patch-clamping Improve KCNH2 -LQTS Variant Classification and Cardiac Event Risk Stratification

medRxiv(2024)10.1101/2024.02.01.24301443

N/A

0.104DataRank · unranked

1 citations

Chai‐Ann Ng, Takanori Aizawa, Luca Sala, Sahej Bains, Annika Winbo +37 more

A Transcriptomic Atlas of the Human Brain Reveals Genetically Determined Aspects of Neuropsychiatric Health

medRxiv(2023)10.1101/2023.03.10.23287072

Top 78%

0.104DataRank

Top 78%1 citations

Eric R. Gamazon, Xavier Bledsoe

A prognostic molecular signature of hepatic steatosis is spatially heterogeneous and dynamic in human liver

UNC Libraries(2024)10.17615/rgww-7041

N/A

0.104DataRank · unranked

1 citations

Kendall Van Keuren‐Jensen, Susan P. Fisher‐Hoch, Nataraja Sarma Vaitinadin, Kaushik Amancherla, Andrew Perry +38 more

Discovering root causal genes with high-throughput perturbations

eLife(2024)10.7554/elife.100949

N/A

0.104DataRank · unranked

1 citations

Eric R. Gamazon, Eric V Strobl

The broad impact of cell death genes on the human disease phenome

Cell Death and Disease(2024)10.1038/s41419-024-06632-7

N/A

0DataRank · unranked

4 citations

Phillip Lin, Eric R. Gamazon, Sandra S. Zinkel, Abigail Rich

BMP Antagonist Gremlin 2 Regulates Hippocampal Neurogenesis and Is Associated with Seizure Susceptibility and Anxiety

eNeuro(2024)10.1523/eneuro.0213-23.2024

N/A

0DataRank · unranked

4 citations

Garrett A. Kaas, Caroline G Firmin, Eric R. Gamazon, Antonis K. Hatzopoulos, Nicolette B Frazer

A multi-modal framework improves prediction of tissue-specific gene expression from a surrogate tissue

EBioMedicine(2024)10.1016/j.ebiom.2024.105305

N/A

0DataRank · unranked

3 citations

Chunfeng He, Jiayao Fan, Yuan Zhou, Chunxiao Cheng, Ran Meng +5 more

NeuroimaGene: an R package for assessing the neurological correlates of genetically regulated gene expression

BMC Bioinformatics(2024)10.1186/s12859-024-05936-x

N/A

0DataRank · unranked

1 citations

Eric R. Gamazon, Xavier Bledsoe

Cardiomyocyte-derived circulating extracellular vesicles allow a non-invasive liquid biopsy of myocardium in health and disease

medRxiv(2024)10.1101/2024.09.19.24314009

N/A

0DataRank · unranked

6 citations

Priyanka Gokulnath, Guoping Li, Elizabeth Hutchins, Bessie Meechoovet, Quanhu Sheng +36 more

Discovering Root Causal Genes with High Throughput Perturbations

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.13.574491

N/A

0DataRank · unranked

1 citations

Eric R. Gamazon, Eric V Strobl

Functionally oriented analysis of cardiometabolic traits in a trans-ethnic sample

UNC Libraries(2024)10.17615/9n0h-7g83

N/A

0DataRank · unranked

0 citations

Richard A. Gibbs, Mandar Karhade, Adán Valladares‐Salgado, D.E. Arking, J.E. Below +20 more

IMMerge: merging imputation data at scale

UNC Libraries(2024)10.17615/0f9j-5h68

N/A

0DataRank · unranked

0 citations

Wenkun Zhu, Hannah G. Polikowsky, Eric R. Gamazon, Hsiao‐Hwa Chen, Alexander S Petty +3 more

Revisiting Some Useful Statistical Guidelines in Circulation Research in Response to a Changing Landscape

UNC Libraries(2024)10.17615/hhsn-ry07

N/A

0DataRank · unranked

0 citations

Jennifer E. Below, Eric R. Gamazon, Heather M. Highland

Transcriptome-Wide Root Causal Inference

medRxiv(2024)10.1101/2024.07.22.24310837

N/A

0DataRank · unranked

0 citations

Eric R. Gamazon, Eric V Strobl

Discovering Root Causal Genes with High Throughput Perturbations

eLife(2024)10.7554/elife.100949.1

N/A

0DataRank · unranked

0 citations

Eric R. Gamazon, Eric V Strobl

Integrated multiomics of pressure overload in the human heart prioritizes targets relevant to heart failure

Nature Communications(2025)10.1038/s41467-025-62201-2

N/A

0DataRank · unranked

8 citations

Andrew Perry, Michelle L Lance, Kaushik Amancherla, Namju Kim, Quanhu Sheng +26 more

The extracellular vesicle transcriptome provides tissue-specific functional genomic annotation relevant to disease susceptibility in obesity

Cell Genomics(2025)10.1016/j.xgen.2025.100925

N/A

0DataRank · unranked

6 citations

Michael J. Betti, Quanhu Sheng, Phillip Lin, Margo P. Emont, Guoping Li +20 more

Transcriptome-wide root causal inference

PLoS Computational Biology(2025)10.1371/journal.pcbi.1013461

N/A

0DataRank · unranked

3 citations

Eric R. Gamazon, Eric V Strobl

Multiomics reveal key inflammatory drivers of severe obesity: IL4R, LILRA5, and OSM

Cell Genomics(2025)10.1016/j.xgen.2025.100784

N/A

0DataRank · unranked

6 citations

Heather M. Highland, Eitan Frankel, Alyssa Scartozzi, Xinruo Zhang, Rashedeh Roshani +34 more

Genetically regulated eRNA expression predicts chromatin contact frequency and reveals genetic mechanisms at GWAS loci

Nature Communications(2025)10.1038/s41467-025-58023-x

N/A

0DataRank · unranked

2 citations

Phillip Lin, Melinda C. Aldrich, Eric R. Gamazon, Michael J. Betti

Human Physiologic Responses to Insulin in Indigenous Americans Identify a Metabolic Susceptibility Profile Linked to Diabetes

Diabetes Care(2025)10.2337/dc25-0151

N/A

0DataRank · unranked

2 citations

Paolo Piaggi, Phillip Lin, Shilin Zhao, Lindsey K. Stolze, Andrew Perry +10 more

Integrating population-level and cell-based signatures for drug repositioning

Bioinformatics(2025)10.1093/bioinformatics/btaf498

N/A

0DataRank · unranked

1 citations

Yue Xu, Yuan Zhou, Jiayao Fan, Chunxiao Cheng, Ran Meng +6 more

Author response: Discovering Root Causal Genes with High Throughput Perturbations

(2025)10.7554/elife.100949.2.sa0

N/A

0DataRank · unranked

0 citations

Eric R. Gamazon, Eric V Strobl

Discovering Root Causal Genes with High Throughput Perturbations

eLife(2025)10.7554/elife.100949.2

N/A

0DataRank · unranked

0 citations

Eric R. Gamazon, Eric V Strobl

First clinical diagnosis of FAME3 via commercial Long-Read sequencing reveals mosaic repeat expansion in MARCHF6 gene

Neurogenetics(2025)10.1007/s10048-025-00835-6

N/A

0DataRank · unranked

0 citations

Russell J. Stewart, Yutaka Furuta, Kimberly Ezell, Lynette Rives, Bethany Nunley +12 more

Neuroimaging transcriptomic analyses of Parkinson’s disease highlight molecular, cellular, and neurobiological mechanisms

npj Parkinson s Disease(2025)10.1038/s41531-025-01149-y

N/A

0DataRank · unranked

0 citations

Michael J. Betti, Eric R. Gamazon, Xavier Bledsoe

A novel serum glucocorticoid regulated kinase 1 inhibitor improves cardiac structure and function in heart failure

Research Square(2025)10.21203/rs.3.rs-7539711/v1

N/A

0DataRank · unranked

0 citations

Sabindra Pradhananga, Dinesh Srinivasan, Marc Vidal, Delphine Labit, Kayluz Frias Boligan +8 more

Additional file 2 of Network reconstruction for trans acting genetic loci using multi-omics data and prior information

Open MIND(2022)10.6084/m9.figshare.21520295

Top 100%

0DataRank

Top 100%0 citations

Ashis Saha, Mélanie Waldenberger, Sonja Kunze, Simone Wahl, Martina Müller‐Nurasyid +11 more

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

UNC Libraries(2020)10.17615/3we9-ae42

Top 100%

0DataRank

Top 100%0 citations

David S. DeLuca, Ayellet V. Segrè, Timothy J. Sullivan, Timothy R. Young, Ellen T. Gelfand +27 more

Epidemiology and Natural History of Preclinical and Clinical Obesity: Insights From a UK Cohort

Obesity(2026)10.1002/oby.70126

N/A

0DataRank · unranked

0 citations

Zhiqi Yao, Seraj N. Grimes, April Kim, Allison W. Peng, Roger S. Blumenthal +6 more

Phenome-based approach identifies RIC1-linked Mendelian syndrome through zebrafish models, biobank associations and clinical studies

Nature Medicine(2020)10.1038/s41591-019-0705-y

N/A

0DataRank · unranked

51 citations

Xinzi Qi, Eric R. Gamazon, D. Melville, Nisha Patel, Amy R. Rushing +8 more

Electronic health record phenotypes associated with genetically regulated expression of CFTR and application to cystic fibrosis

Genetics in Medicine(2020)10.1038/s41436-020-0786-5

N/A

0DataRank · unranked

13 citations

Zhijun Yin, Gengjie Jia, Dan Zhou, Qiang Wei, Annika Faucon +8 more

An analysis of genetically regulated gene expression across multiple tissues implicates novel gene candidates in Alzheimer’s disease

Alzheimer s Research & Therapy(2020)10.1186/s13195-020-00611-8

N/A

0DataRank · unranked

31 citations

Michelle K. Lupton, Daniel Edey, Eric R. Gamazon, Eske M. Derks, Zachary F. Gerring

An integrative systems‐based analysis of substance use: eQTL‐informed gene‐based tests, gene networks, and biological mechanisms

American Journal of Medical Genetics Part B Neuropsychiatric Genetics(2020)10.1002/ajmg.b.32829

N/A

0DataRank · unranked

5 citations

Angela Mina-Vargas, Eric R. Gamazon, Eske M. Derks, Zachary F. Gerring

Genetic architecture of host proteins interacting with SARS-CoV-2

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.01.182709

N/A

0DataRank · unranked

15 citations

Eleanor Wheeler, Julia Carrasco-Zanini, Johannes Raffler, Nicola D. Kerrison, Erin Oerton +13 more

The genetic architecture of human infectious diseases and pathogen-induced cellular phenotypes

medRxiv(2020)10.1101/2020.07.19.20157404

N/A

0DataRank · unranked

6 citations

Dan Zhou, Rebecca L. Sale, Lisa Bastarache, Liuyang Wang, Sandra S. Zinkel +4 more

Gene Expression Imputation with Generative Adversarial Imputation Nets

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.09.141689

N/A

0DataRank · unranked

4 citations

Tiago Azevedo, Eric R. Gamazon, Píetro Lió, Ramon Viñas

Multilayer modelling and analysis of the human transcriptome

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.21.109082

N/A

0DataRank · unranked

0 citations

Giovanna Maria Dimitri, Píetro Lió, Eric R. Gamazon, Tiago Azevedo

Discovery and Functional Assessment of Gene Variants in the Vascular Endothelial Growth Factor Pathway

UNC Libraries(2020)10.17615/g5yd-3r34

N/A

0DataRank · unranked

0 citations

Dylan M. Glubb, Amy S. Etheridge, Shiwei Duan, Anna Di Rienzo, Patrick Evans +5 more

A transcriptome-wide association study of Alzheimer’s disease using prediction models of relevant tissues identifies novel candidate susceptibility genes

Genome Medicine(2021)10.1186/s13073-021-00959-y

N/A

0DataRank · unranked

84 citations

Jingjing Zhu, Dan Zhou, Saranya Canchi, Chong Wu, Nancy J. Cox +4 more

E-MAGMA: an eQTL-informed method to identify risk genes using genome-wide association study summary statistics

Bioinformatics(2021)10.1093/bioinformatics/btab115

N/A

0DataRank · unranked

67 citations

Angela Mina-Vargas, Eric R. Gamazon, Eske M. Derks, Zachary F. Gerring

Genetically regulated expression in late-onset Alzheimer’s disease implicates risk genes within known and novel loci

Translational Psychiatry(2021)10.1038/s41398-021-01677-0

N/A

0DataRank · unranked

40 citations

Lauren E. Petty, Jin Sha, Yi Zhao, Amanda B Kuzma, Otto Valladares +5 more

Contextualizing genetic risk score for disease screening and rare variant discovery

Nature Communications(2021)10.1038/s41467-021-24387-z

N/A

0DataRank · unranked

31 citations

Dongmei Yu, Jeremiah M. Scharf, Carol A. Mathews, Lauren M. McGrath, Edwin H. Cook +4 more

A transcriptome-wide association study identifies novel blood-based gene biomarker candidates for Alzheimer’s disease risk

Human Molecular Genetics(2021)10.1093/hmg/ddab229

N/A

0DataRank · unranked

19 citations

Dan Zhou, Md Rezanur Rahman, Jingjing Zhu, Dalia Ghoneim, Nancy J. Cox +5 more

Deep Learning Enables Fast and Accurate Imputation of Gene Expression

Frontiers in Genetics(2021)10.3389/fgene.2021.624128

N/A

0DataRank · unranked

18 citations

Tiago Azevedo, Eric R. Gamazon, Píetro Lió, Ramon Viñas

Global biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts

medRxiv(2021)10.1101/2021.11.18.21266545

N/A

0DataRank · unranked

25 citations

Shinichi Namba, Esteban A. Lopera-Maya, Sini Kerminen, Kristin Tsuo, Kristi Läll +25 more

Best practices for multi-ancestry, meta-analytic transcriptome-wide association studies: lessons from the Global Biobank Meta-analysis Initiative

medRxiv(2021)10.1101/2021.11.24.21266825

N/A

0DataRank · unranked

11 citations

Jibril Hirbo, Dan Zhou, Wei Zhou, Jie Zheng, Masahiro Kanai +5 more

Modeling mutational effects on biochemical phenotypes using convolutional neural networks: application to SARS-CoV-2

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.28.428521

N/A

0DataRank · unranked

5 citations

Eric R. Gamazon, Bo Wang

Genome-wide association study reveals genetic risk factors for trigeminal neuralgia

medRxiv(2021)10.1101/2021.02.08.21251349

N/A

0DataRank · unranked

5 citations

Jing He, Oluwatoyin Akinnusotu, Rebecca L. Sale, Janey Wang, Lisa Bastarache +2 more

Towards mechanistic models of mutational effects: Deep Learning on Alzheimer’s Aβ peptide

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.19.473403

N/A

0DataRank · unranked

1 citations

Eric R. Gamazon, Bo Wang

A Local Genetic Correlation Analysis Provides Biological Insights Into the Shared Genetic Architecture of Psychiatric and Substance Use Phenotypes

Biological Psychiatry(2022)10.1016/j.biopsych.2022.03.001

N/A

0DataRank · unranked

28 citations

Jackson G. Thorp, Eric R. Gamazon, Eske M. Derks, Zachary F. Gerring

An analysis of genetically regulated gene expression and the role of co-expression networks across 16 psychiatric and substance use phenotypes

European Journal of Human Genetics(2022)10.1038/s41431-022-01037-6

N/A

0DataRank · unranked

11 citations

Jackson G. Thorp, Eric R. Gamazon, Eske M. Derks, Zachary F. Gerring

Modeling mutational effects on biochemical phenotypes using convolutional neural networks: application to SARS-CoV-2

iScience(2022)10.1016/j.isci.2022.104500

N/A

0DataRank · unranked

6 citations

Eric R. Gamazon, Bo Wang

IMMerge: merging imputation data at scale

Bioinformatics(2022)10.1093/bioinformatics/btac750

N/A

0DataRank · unranked

7 citations

Hung‐Hsin Chen, Alexander S Petty, Lauren E. Petty, Hannah G. Polikowsky, Eric R. Gamazon +3 more

Integrative transcriptomic, evolutionary, and causal inference framework for region-level analysis: Application to COVID-19

npj Genomic Medicine(2022)10.1038/s41525-022-00296-y

N/A

0DataRank · unranked

4 citations

Eric R. Gamazon, Dan Zhou

Hypergraph factorisation for multi-tissue gene expression imputation

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.31.502211

N/A

0DataRank · unranked

1 citations

Chaitanya K. Joshi, Dobrik Georgiev, Bianca Dumitrascu, Eric R. Gamazon, Píetro Lió +1 more

Integrative genetic analysis identifies FLVCR1 as an essential component of choline transport in mammals

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.05.509986

N/A

0DataRank · unranked

1 citations

Artem Khan, Yeeun Son, Lishu Yue, Søren Heissel, Eric R. Gamazon +4 more

Mechanistic Deep Learning Framework on Cell Traits Derived from Single-Cell Mass Cytometry Data

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.22.504669

N/A

0DataRank · unranked

0 citations

Sandra S. Zinkel, Eric R. Gamazon, Bo Wang

Integrative genetic analysis identifies FLVCR1 as a plasma-membrane choline transporter in mammals

Cell Metabolism(2023)10.1016/j.cmet.2023.04.003

N/A

0DataRank · unranked

74 citations

Artem Khan, Yeeun Son, Lishu Yue, Søren Heissel, Anurag Sharma +7 more

Hypergraph factorization for multi-tissue gene expression imputation

Nature Machine Intelligence(2023)10.1038/s42256-023-00684-8

N/A

0DataRank · unranked

30 citations

Chaitanya K. Joshi, Dobrik Georgiev, Phillip Lin, Bianca Dumitrascu, Eric R. Gamazon +2 more

A phenome-wide scan reveals convergence of common and rare variant associations

Genome Medicine(2023)10.1186/s13073-023-01253-9

N/A

0DataRank · unranked

16 citations

Yuan Zhou, Yue Xu, Ran Meng, Eric R. Gamazon, Dan Zhou

Analysis of genetically determined gene expression suggests role of inflammatory processes in exfoliation syndrome

BMC Genomics(2023)10.1186/s12864-023-09179-7

N/A

0DataRank · unranked

10 citations

Francesca Pasutto, Eric R. Gamazon, Patrick Evans, Priyanka Pawar, Daniel Berner +12 more

Identification of drug repurposing candidates for the treatment of anxiety: A genetic approach

Psychiatry Research(2023)10.1016/j.psychres.2023.115343

N/A

0DataRank · unranked

9 citations

Jackson G. Thorp, Wọlé Akóṣílè, Jue‐Sheng Ong, Eric R. Gamazon, Eske M. Derks +2 more

Towards mechanistic models of mutational effects: Deep learning on Alzheimer’s Aβ peptide

Computational and Structural Biotechnology Journal(2023)10.1016/j.csbj.2023.03.051

N/A

0DataRank · unranked

3 citations

Shahab Razavi, Eric R. Gamazon, Bo Wang

Minimum entropy framework identifies a novel class of genomic functional elements and reveals regulatory mechanisms at human disease loci

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.11.544507

N/A

0DataRank · unranked

6 citations

Melinda C. Aldrich, Eric R. Gamazon, Michael J. Betti

Integrating population-level and cell-based signatures for drug repositioning

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.25.564079

N/A

0DataRank · unranked

2 citations

Yue Xu, Yuan Zhou, Jiayao Fan, Chunxiao Cheng, Ran Meng +6 more

Mapping the landscape of lineage-specific dynamic regulation of gene expression using single-cell transcriptomics and application to genetics of complex disease

medRxiv(2023)10.1101/2023.10.24.23297476

N/A

0DataRank · unranked

2 citations

P. Charles Lin, Dan Zhou, Douglas M. Ruderfer, Eric R. Gamazon, Hanna Abe

The broad impact of cell death genes on the human disease phenome

medRxiv(2023)10.1101/2023.06.11.23291256

N/A

0DataRank · unranked

1 citations

Phillip Lin, Eric R. Gamazon, Sandra S. Zinkel, Abigail Rich

Data from Integration of Cell Line and Clinical Trial Genome-Wide Analyses Supports a Polygenic Architecture of Paclitaxel-Induced Sensory Peripheral Neuropathy

(2023)10.1158/1078-0432.c.6523037

N/A

0DataRank · unranked

0 citations

Eric R. Gamazon, Claudia Wing, Uchenna O. Njiaju, Chidiamara Njoku, Robert Michael Baldwin +15 more

Transcriptome analysis of cardiac endothelial cells after myocardial infarction reveals temporal changes and long-term deficits

Scientific Reports(2024)10.1038/s41598-024-59155-8

N/A

0DataRank · unranked

24 citations

Presley L. Cannon, Cassandra P. Awgulewitsch, Cristi L. Galindo, Eric R. Gamazon, Antonis K. Hatzopoulos +1 more

Cross-ancestry analysis of brain QTLs enhances interpretation of schizophrenia genome-wide association studies

The American Journal of Human Genetics(2024)10.1016/j.ajhg.2024.09.001

N/A

0DataRank · unranked

18 citations

Sihan Liu, Zongyao Ren, Feiran Wang, Qiuman Liang, Yi Jiang +23 more

Transcriptome‐Wide Association Studies (TWAS): Methodologies, Applications, and Challenges

Current Protocols(2024)10.1002/cpz1.981

N/A

0DataRank · unranked

16 citations

Taylor Nagai, Anuar Konkashbaev, Dan Zhou, Ela W. Knapik, Eric R. Gamazon +1 more

Myeloid-Specific JAK2 Contributes to Inflammation and Salt Sensitivity of Blood Pressure

Circulation Research(2024)10.1161/circresaha.124.323595

N/A

0DataRank · unranked

16 citations

Luul A. Aden, Ashley Pitzer Mutchler, C. Basu, Lale A. Ertuğlu, Quanhu Sheng +23 more

A transcriptomic atlas of the human brain reveals genetically determined aspects of neuropsychiatric health

The American Journal of Human Genetics(2024)10.1016/j.ajhg.2024.06.002

N/A

0DataRank · unranked

9 citations

Eric R. Gamazon, Xavier Bledsoe

Eric R. Gamazon

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