Rajendra Karki

Also affiliated with Nepal Development Research Institute, National University College, Institute of Molecular Biology, NLR Nepal

Biochemistry, Genetics and Molecular BiologyImmunology and MicrobiologyChemistry

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 30 papers. Top paper: “Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes”.

Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes

Cell(2020)10.1016/j.cell.2020.11.025

N/A

1.1DataRank · unranked

1740 citations

Bhesh Raj Sharma, Shraddha Tuladhar, Evan P. Williams, Lillian Zalduondo, Parimal Samir +11 more

TLR2 senses the SARS-CoV-2 envelope protein to produce inflammatory cytokines

Nature Immunology(2021)10.1038/s41590-021-00937-x

N/A

0.964DataRank · unranked

619 citations

Rajendra Karki, Evan P. Williams, Dong Yang, Elizabeth Fitzpatrick, Peter Vogel +3 more

The ‘cytokine storm’: molecular mechanisms and therapeutic prospects

Trends in Immunology(2021)10.1016/j.it.2021.06.001

N/A

0.909DataRank · unranked

428 citations

Thirumala‐Devi Kanneganti, Rajendra Karki

ZBP1 promotes fungi-induced inflammasome activation and pyroptosis, apoptosis, and necroptosis (PANoptosis)

Journal of Biological Chemistry(2020)10.1074/jbc.ra120.015924

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0.820DataRank · unranked

236 citations

Shraddha Tuladhar, Rajendra Karki, Bhesh Raj Sharma, Benoit Briard, Sannula Kesavardhana +3 more

RIPK1 Distinctly Regulates Yersinia-Induced Inflammatory Cell Death, PANoptosis

ImmunoHorizons(2020)10.4049/immunohorizons.2000097

N/A

0.806DataRank · unranked

214 citations

Sannula Kesavardhana, Rajendra Karki, Balabhaskararao Kancharana, Amanda R. Burton, Thirumala‐Devi Kanneganti +1 more

Impaired NLRP3 inflammasome activation/pyroptosis leads to robust inflammatory cell death via caspase-8/RIPK3 during coronavirus infection

Journal of Biological Chemistry(2020)10.1074/jbc.ra120.015036

N/A

0.798DataRank · unranked

204 citations

Evan P. Williams, R. K. Subbarao Malireddi, Rajendra Karki, Balaji Banoth, Amanda R. Burton +5 more

ADAR1 and ZBP1 in innate immunity, cell death, and disease

Trends in Immunology(2023)10.1016/j.it.2023.01.001

N/A

0.708DataRank · unranked

111 citations

Thirumala‐Devi Kanneganti, Rajendra Karki

Immune regulator IRF1 contributes to ZBP1-, AIM2-, RIPK1-, and NLRP12-PANoptosome activation and inflammatory cell death (PANoptosis)

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.105141

N/A

0.706DataRank · unranked

110 citations

Rajendra Karki, Y. Rajesh, Thirumala‐Devi Kanneganti, Bhesh Raj Sharma

Cutting Edge: Caspase-8 Is a Linchpin in Caspase-3 and Gasdermin D Activation to Control Cell Death, Cytokine Release, and Host Defense during Influenza A Virus Infection

The Journal of Immunology(2021)10.4049/jimmunol.2100757

N/A

0.557DataRank · unranked

40 citations

Rajendra Karki, Min Zheng, Balabhaskararao Kancharana, SangJoon Lee, Sannula Kesavardhana +4 more

A comparative study of apoptosis, pyroptosis, necroptosis, and PANoptosis components in mouse and human cells

PLoS ONE(2024)10.1371/journal.pone.0299577

N/A

0.505DataRank · unranked

28 citations

Roman Sarkar, Rajendra Karki, Thirumala‐Devi Kanneganti, Sk Mohiuddin Choudhury

Gasdermin D Promotes AIM2 Inflammasome Activation and Is Required for Host Protection against Francisella novicida

The Journal of Immunology(2020)10.4049/jimmunol.204.supp.227.30

N/A

0.269DataRank · unranked

5 citations

Qi Fan Zhu, Arjun Balakrishnan, Rajendra Karki, Thirumala-Devi Kanneganti, Min zheng

Synergism of TNF-α and IFN-γ triggers inflammatory cell death, tissue damage, and mortality in SARS-CoV-2 infection and cytokine shock syndromes

PubMed(2020)10.1101/2020.10.29.361048

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0DataRank · unranked

36 citations

Bhesh Raj Sharma, Shraddha Tuladhar, Evan P. Williams, Lillian Zalduondo, Parimal Samir +11 more

AIM2 forms a complex with pyrin and ZBP1 to drive PANoptosis and host defence

Nature(2021)10.1038/s41586-021-03875-8

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0DataRank · unranked

762 citations

Rajendra Karki, Yaqiu Wang, Lam Nhat Nguyen, Ravi Kalathur, Thirumala‐Devi Kanneganti +1 more

Interferon inducible GBPs restrict Burkholderia thailandensis motility induced cell-cell fusion

PLoS Pathogens(2020)10.1371/journal.ppat.1008364

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0DataRank · unranked

27 citations

Benoit Briard, Parimal Samir, Rajendra Karki, Anannya Bhattacharya, Clifford S. Guy +7 more

IRF8 Regulates Gram-Negative Bacteria–Mediated NLRP3 Inflammasome Activation and Cell Death

The Journal of Immunology(2020)10.4049/jimmunol.1901508

N/A

0DataRank · unranked

31 citations

Ein Lee, Bhesh Raj Sharma, Balaji Banoth, Thirumala‐Devi Kanneganti, Rajendra Karki

ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis

Cell Reports(2021)10.1016/j.celrep.2021.109858

N/A

0DataRank · unranked

410 citations

Balamurugan Sundaram, Bhesh Raj Sharma, SangJoon Lee, R. K. Subbarao Malireddi, Lam Nhat Nguyen +8 more

Inflammatory Cell Death, PANoptosis, Mediated by Cytokines in Diverse Cancer Lineages Inhibits Tumor Growth

ImmunoHorizons(2021)10.4049/immunohorizons.2100059

N/A

0DataRank · unranked

191 citations

Rajendra Karki, Balamurugan Sundaram, Balabhaskararao Kancharana, SangJoon Lee, Parimal Samir +2 more

DDX3X coordinates host defense against influenza virus by activating the NLRP3 inflammasome and type I interferon response

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.100579

N/A

0DataRank · unranked

60 citations

Parimal Samir, Min Zheng, R. K. Subbarao Malireddi, Rajendra Karki, Bhesh Raj Sharma +5 more

Ets-2 deletion in myeloid cells attenuates IL-1α-mediated inflammatory disease caused by a Ptpn6 point mutation

Cellular and Molecular Immunology(2020)10.1038/s41423-020-0398-7

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0DataRank · unranked

11 citations

Prajwal Gurung, Rajendra Karki, Amanda R. Burton, Paul J. Hertzog, Thirumala‐Devi Kanneganti +1 more

Caspase-6 promotes activation of the caspase-11-NLRP3 inflammasome during gram-negative bacterial infections

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.101379

N/A

0DataRank · unranked

23 citations

Rajendra Karki, Balabhaskararao Kancharana, Hartmut Berns, Shondra M. Pruett‐Miller, Thirumala‐Devi Kanneganti +1 more

Innate immunity, cytokine storm, and inflammatory cell death in COVID-19

Journal of Translational Medicine(2022)10.1186/s12967-022-03767-z

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0DataRank · unranked

122 citations

Thirumala‐Devi Kanneganti, Rajendra Karki

Pancancer transcriptomic profiling identifies key PANoptosis markers as therapeutic targets for oncology

NAR Cancer(2022)10.1093/narcan/zcac033

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0DataRank · unranked

50 citations

Ratnakar R. Bynigeri, Rajendra Karki, R. K. Subbarao Malireddi, Bhesh Raj Sharma, Thirumala‐Devi Kanneganti +1 more

Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation

Cell Reports(2022)10.1016/j.celrep.2022.111434

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0DataRank · unranked

36 citations

Rajendra Karki, Raghvendra Mall, Bhesh Raj Sharma, Ravi Kalathur, SangJoon Lee +5 more

NLRP12-PANoptosome activates PANoptosis and pathology in response to heme and PAMPs

Cell(2023)10.1016/j.cell.2023.05.005

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0DataRank · unranked

392 citations

Pandian Nagakannan, Raghvendra Mall, Yaqiu Wang, Roman Sarkar, Hee Jin Kim +6 more

PANoptosome signaling and therapeutic implications in infection: central role for ZBP1 to activate the inflammasome and PANoptosis

Current Opinion in Immunology(2023)10.1016/j.coi.2023.102348

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0DataRank · unranked

117 citations

Thirumala‐Devi Kanneganti, Rajendra Karki

Galactosaminogalactan activates the inflammasome to provide host protection

Nature(2020)10.1038/s41586-020-2996-z

N/A

0DataRank · unranked

129 citations

Thierry Fontaine, Parimal Samir, David E. Place, Laetitia Muszkieta, R. K. Subbarao Malireddi +13 more

Interferon regulatory factor 1 regulates PANoptosis to prevent colorectal cancer

JCI Insight(2020)10.1172/jci.insight.136720

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0DataRank · unranked

279 citations

Bhesh Raj Sharma, Ein Lee, Balaji Banoth, R. K. Subbarao Malireddi, Parimal Samir +6 more

NINJ1 mediates inflammatory cell death, PANoptosis, and lethality during infection conditions and heat stress

Nature Communications(2024)10.1038/s41467-024-45466-x

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0DataRank · unranked

91 citations

Rajendra Karki, R. K. Subbarao Malireddi, Raghvendra Mall, Roman Sarkar, Bhesh Raj Sharma +7 more

Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense

Cell(2020)10.1016/j.cell.2020.03.040

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0DataRank · unranked

543 citations

Rajendra Karki, Peter Vogel, Thirumala‐Devi Kanneganti, Min Zheng

Identification of the PANoptosome: A Molecular Platform Triggering Pyroptosis, Apoptosis, and Necroptosis (PANoptosis)

Frontiers in Cellular and Infection Microbiology(2020)10.3389/fcimb.2020.00237

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0DataRank · unranked

560 citations

Min Zheng, Sannula Kesavardhana, Rajendra Karki, R. K. Subbarao Malireddi, Balaji Banoth +8 more