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AIM2 forms a complex with pyrin and ZBP1 to drive PANoptosis and host defence

Nature(2021)10.1038/s41586-021-03875-8Source: DataRank Database

AIM2 forms a complex with pyrin and ZBP1 to drive PANoptosis and host defence is a research paper published in Nature (2021). On theSindex it has a DataRank of 0. It has been cited 762 times.

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Open Access762 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (16 grants)Impact (FWCI 29.85)OA: greenTopics (57)Linked Datasets (24)DataCite Reuse (24)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

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Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

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Reusable (0/3)

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Authors (6)

Rajendra Karki ORCID,Yaqiu Wang ORCID,Lam Nhat Nguyen ORCID,Ravi Kalathur ORCID,Thirumala‐Devi Kanneganti ORCID

Live enrichment

PubMed:34471287 PMC:PMC8603942 OpenAlex:https://openalex.org/W3197986920

NIH HHS

Grant: AI101935

NCI NIH HHS

Grant: R35 CA253095

NIAID NIH HHS

Grant: R37 AI101935

NIH HHS

Grant: AR056296

NIH HHS

Grant: AI124346

NIAID NIH HHS

Grant: R01 AI101935

NIH HHS

Grant: AI160179

NIAID NIH HHS

Grant: R01 AI124346

NIAMS NIH HHS

Grant: R01 AR056296

NIH HHS

Grant: CA253095

NIAID NIH HHS

Grant: R01 AI160179

National Institutes of Health

Grant: 5R01AI124346-07

Innate immune signaling and stress response

National Institutes of Health

Grant: 5R01AI160179-02

Targeting innate immune pathways, and inflammatory cell death in cytokine-mediated diseases

National Institutes of Health

Grant: 5R01AR056296-15

Role of IL-1alpha signaling in inflammatory diseases and host defense

National Institutes of Health

Grant: 5R35CA253095-04

Innate immune sensors, inflammasomes, and inflammasome-mediated processes in cancer

National Institutes of Health

Grant: 5R37AI101935-10

Inflammatory Caspases in Innate Immunity and Inflammation

FWCI

29.85

Citation Percentile

1.0%

Citation Trend

2013

2021

2022

2023

2024

2025

2026

greenLicense: cc-by

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8603942

publisherhttps://www.nature.com/articles/s41586-021-03875-8.pdf

publisherhttps://www.nature.com/articles/s41586-021-03875-8

journalhttps://doi.org/10.1038/s41586-021-03875-8

Fields of Study

Inflammasome and immune disordersinterferon and immune responsesImmune Response and Inflammation0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

PyroptosisPyrinTHP-1 CellsNecroptosisAnimalsCells, CulturedDNA-Binding ProteinsFemaleFrancisellaHumansMaleMice, Inbred C57BLCytokinesRNA-Binding ProteinsApoptosisHerpesvirus 1, HumanCaspase 1Mice

Keywords

AIM2Pyrin domainInflammasomeInnate immune systemBiologyCaspase 1Programmed cell deathNALP3RIPK1Cell biologyImmunologyImmune systemNecroptosisInflammationApoptosisGeneticsMale571THP-1 CellsRNA-Binding ProteinsHerpesvirus 1, HumanPyrinArticleDNA-Binding ProteinsMice, Inbred C57BLMicePyroptosisAnimalsCytokinesHumansFemaleFrancisellaCells, Cultured

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

Additional file 1 of Systematic transcriptome profiling of pyroptosis related signature for predicting prognosis and immune landscape in lower grade glioma

10.6084/m9.figshare.20488440.v1figshare

Additional file 1 of Systematic transcriptome profiling of pyroptosis related signature for predicting prognosis and immune landscape in lower grade glioma

10.6084/m9.figshare.20488440figshare

Additional file 2 of Systematic transcriptome profiling of pyroptosis related signature for predicting prognosis and immune landscape in lower grade glioma

10.6084/m9.figshare.20488443.v1figshare

Additional file 2 of Systematic transcriptome profiling of pyroptosis related signature for predicting prognosis and immune landscape in lower grade glioma

10.6084/m9.figshare.20488443figshare

Additional file 3 of Systematic transcriptome profiling of pyroptosis related signature for predicting prognosis and immune landscape in lower grade glioma

10.6084/m9.figshare.20488446.v1figshare

Additional file 3 of Systematic transcriptome profiling of pyroptosis related signature for predicting prognosis and immune landscape in lower grade glioma

10.6084/m9.figshare.20488446figshare

Additional file 2 of Fusobacterium nucleatum triggers proinflammatory cell death via Z-DNA binding protein 1 in apical periodontitis

10.6084/m9.figshare.22609025.v1figshare

Additional file 2 of Fusobacterium nucleatum triggers proinflammatory cell death via Z-DNA binding protein 1 in apical periodontitis

10.6084/m9.figshare.22609025figshare

Additional file 1 of Multiomics characterization of pyroptosis in the tumor microenvironment and therapeutic relevance in metastatic melanoma

10.6084/m9.figshare.25010344.v1figshare

Additional file 1 of Multiomics characterization of pyroptosis in the tumor microenvironment and therapeutic relevance in metastatic melanoma

10.6084/m9.figshare.25010344figshare

Additional file 1 of Identification of PANoptosis-related signature reveals immune infiltration characteristics and immunotherapy responses for renal cell carcinoma

10.6084/m9.figshare.25341104.v1figshare

Additional file 1 of Identification of PANoptosis-related signature reveals immune infiltration characteristics and immunotherapy responses for renal cell carcinoma

10.6084/m9.figshare.25341104figshare

Additional file 2 of Multiomics characterization of pyroptosis in the tumor microenvironment and therapeutic relevance in metastatic melanoma

10.6084/m9.figshare.25010519figshare

Additional file 2 of Multiomics characterization of pyroptosis in the tumor microenvironment and therapeutic relevance in metastatic melanoma

10.6084/m9.figshare.25010519.v1figshare

Additional file 1 of A slow-releasing donor of hydrogen sulfide inhibits neuronal cell death via anti-PANoptosis in rats with spinal cord ischemia‒reperfusion injury

10.6084/m9.figshare.24993699.v1figshare

Additional file 1 of A slow-releasing donor of hydrogen sulfide inhibits neuronal cell death via anti-PANoptosis in rats with spinal cord ischemia‒reperfusion injury

10.6084/m9.figshare.24993699figshare

Additional file 7 of Systematic transcriptome profiling of pyroptosis related signature for predicting prognosis and immune landscape in lower grade glioma

10.6084/m9.figshare.20488458.v1figshare

Additional file 6 of Systematic transcriptome profiling of pyroptosis related signature for predicting prognosis and immune landscape in lower grade glioma

10.6084/m9.figshare.20488455figshare

Additional file 5 of Systematic transcriptome profiling of pyroptosis related signature for predicting prognosis and immune landscape in lower grade glioma

10.6084/m9.figshare.20488452.v1figshare

Additional file 7 of Systematic transcriptome profiling of pyroptosis related signature for predicting prognosis and immune landscape in lower grade glioma

10.6084/m9.figshare.20488458figshare