Tamar Tchkonia

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 82 papers. Top paper: “Senescent Cells: Emerging Targets for Human Aging and Age-Related Diseases”.

Senescent Cells: Emerging Targets for Human Aging and Age-Related Diseases

Trends in Biochemical Sciences(2020)10.1016/j.tibs.2020.03.008

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4.2DataRank · unranked

196 citations

Eric W.‐F. Lam, Tamar Tchkonia, James L. Kirkland, Yu Sun, Shuling Song

TNF‐α/IFN‐γ synergy amplifies senescence‐associated inflammation and SARS‐CoV‐2 receptor expression via hyper‐activated JAK/STAT1

Aging Cell(2022)10.1111/acel.13646

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2.8DataRank · unranked

119 citations

Xiaomeng Yang, Tamar Tchkonia, George M. Martin, James L. Kirkland, Junko Oshima +1 more

Interleukin-6 in Patients With Heart Failure and Preserved Ejection Fraction

JACC Heart Failure(2023)10.1016/j.jchf.2023.06.031

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2.1DataRank · unranked

119 citations

Katlyn E. Koepp, Michael S. Sabbah, Jair Machado Espindola Netto, Michael D. Jensen, James L. Kirkland +10 more

Effects of intermittent senolytic therapy on bone metabolism in postmenopausal women: a phase 2 randomized controlled trial

Nature Medicine(2024)10.1038/s41591-024-03096-2

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1.7DataRank · unranked

98 citations

Elizabeth J. Atkinson, Sara J. Achenbach, Tammie L. Volkman, Amanda Tweed, Stephanie J. B. Vos +13 more

Senolytic drugs: from discovery to translation

Journal of Internal Medicine(2020)10.1111/joim.13141

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1.0DataRank · unranked

1050 citations

Tamar Tchkonia, James L. Kirkland

Senolytic Combination of Dasatinib and Quercetin Alleviates Intestinal Senescence and Inflammation and Modulates the Gut Microbiome in Aged Mice

The Journals of Gerontology Series A(2021)10.1093/gerona/glab002

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0.826DataRank · unranked

246 citations

Ravinder Nagpal, Hariom Yadav, Marcelo Borges Cavalcante, Allancer Divino de Carvalho Nunes, Augusto Schneider +9 more

Discovery, development, and future application of senolytics: theories and predictions

FEBS Journal(2020)10.1111/febs.15264

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0.766DataRank · unranked

164 citations

Yi Zhu, Tamar Tchkonia, James L. Kirkland, Erin O. Wissler Gerdes

Dasatinib plus quercetin prevents uterine age-related dysfunction and fibrosis in mice

Aging(2020)10.18632/aging.102772

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0.659DataRank · unranked

80 citations

Tatiana D. Saccon, Allancer Nunes, James L. Kirkland, Tamar Tchkonia, Augusto Schneider +2 more

Selective Vulnerability of Senescent Glioblastoma Cells to BCL-XL Inhibition

Molecular Cancer Research(2022)10.1158/1541-7786.mcr-21-0029

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0.619DataRank · unranked

61 citations

Ian Olson, Moustafa Mansour, Lucas P. Carlstrom, Rujapope Sutiwisesak, Rehan Saber +17 more

Astaxanthin and meclizine extend lifespan in UM-HET3 male mice; fisetin, SG1002 (hydrogen sulfide donor), dimethyl fumarate, mycophenolic acid, and 4-phenylbutyrate do not significantly affect lifespan in either sex at the doses and schedules used

GeroScience(2023)10.1007/s11357-023-01011-0

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0.606DataRank · unranked

56 citations

Randy Strong, Peter C. Reifsnyder, Nadia Rosenthal, Ron Korstanje, Elizabeth Fernández +24 more

Cellular senescence in skin‐related research: Targeted signaling pathways and naturally occurring therapeutic agents

Aging Cell(2023)10.1111/acel.13845

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0.590DataRank · unranked

50 citations

Justyna Gornowicz‐Porowska, Adriana Polańska, Violetta Krajka‐Kuźniak, Maciej Stawny, Aleksandra Gostyńska +9 more

Role of senescence in the chronic health consequences of COVID-19

Translational research(2021)10.1016/j.trsl.2021.10.003

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0.553DataRank · unranked

39 citations

Greg Vanichkachorn, Brandon P. Verdoorn, Gregory J. Hanson, Avni Y. Joshi, Mohammad Hassan Murad +5 more

Evaluation of exploratory fluid biomarkers from a phase 1 senolytic trial in mild Alzheimer’s disease

Neurotherapeutics(2025)10.1016/j.neurot.2025.e00591

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0.548DataRank · unranked

13 citations

Juan Pablo Palavicini, Justin Melendez, Nicolas R. Barthélemy, Yingxin He, Tiffany F. Kautz +22 more

In vitro and in vivo effects of zoledronic acid on senescence and senescence-associated secretory phenotype markers

Aging(2023)10.18632/aging.204701

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0.533DataRank · unranked

34 citations

Dominik Saul, Lei Zhang, Zaira Aversa, Madison L. Doolittle, Jad Sfeir +14 more

Activin A Antagonism with Follistatin Reduces Kidney Fibrosis, Injury, and Cellular Senescence-Associated Inflammation in Murine Diabetic Kidney Disease

Kidney360(2025)10.34067/kid.0000000776

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0.426DataRank · unranked

10 citations

Zachary K. Snow, C. Zinn, Cody Gowan, Sabena M. Conley, Anastasia L. Bratulin +7 more

Senolytics To slOw Progression of Sepsis (STOP-Sepsis) in elderly patients: Study protocol for a multicenter, randomized, adaptive allocation clinical trial

Trials(2024)10.1186/s13063-024-08474-2

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0.425DataRank · unranked

8 citations

David A. Wacker, Brian E. Driver, Abbey Staugaitis, Laura J. Niedernhofer, E Schmidt +19 more

Clinicopathological and cellular senescence biomarkers in chronic stalled wounds

International Journal of Dermatology(2024)10.1111/ijd.17072

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0.396DataRank · unranked

13 citations

P. Gómez, Larissa Prata, Julia S. Lehman, Tamar Tchkonia, James L. Kirkland +3 more

Senescence profiling of monoclonal gammopathies reveals paracrine senescence as a crucial defense against disease progression

Leukemia(2025)10.1038/s41375-025-02572-z

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0.253DataRank · unranked

4 citations

Marta Diaz‐delCastillo, Angelo Jose Guilatco, Bilal Mohamad El-Masri, Fatima Mustapha, Michael Tveden Gundesen +13 more

Partial inhibition of mitochondrial complex I attenuates neurodegeneration and restores energy homeostasis and synaptic function in a symptomatic Alzheimer’s mouse model

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.01.182428

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0.165DataRank · unranked

2 citations

Sergey Trushin, Anthony Sheu, Layla Khalili, Su-Youne Chang, Xing Li +31 more

Effects of inhibition of Janus kinase signalling during controlled mechanical ventilation on the rate of skeletal muscle protein synthesis

The Journal of Physiology(2025)10.1113/jp288982

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0.104DataRank · unranked

1 citations

Mahalakshmi Shankaran, Lars Larsson, Nicola Cacciani, Yvette Hedström, James L. Kirkland +5 more

Fisetin for COVID ‐19 in skilled nursing facilities: Senolytic trials in the COVID era

Journal of the American Geriatrics Society(2021)10.1111/jgs.17416

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0DataRank · unranked

49 citations

Tamara K. Evans, Gregory J. Hanson, Yi Zhu, Larissa Prata, Robert J. Pignolo +22 more

Epigenetic and senescence markers indicate an accelerated ageing-like state in women with preeclamptic pregnancies

EBioMedicine(2021)10.1016/j.ebiom.2021.103536

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0DataRank · unranked

38 citations

Ranine Ghamrawi, Hajrunisa Čubro, Haitao Tu, Wendy White, Yvonne S. Butler Tobah +12 more

miR-146a-5p modulates cellular senescence and apoptosis in visceral adipose tissue of long-lived Ames dwarf mice and in cultured pre-adipocytes

GeroScience(2021)10.1007/s11357-021-00490-3

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0DataRank · unranked

35 citations

Moritz Weigl, Augusto Schneider, Sarah Noureddine, Lin Yu, Collin Lahde +9 more

FBF1 deficiency promotes beiging and healthy expansion of white adipose tissue

Cell Reports(2021)10.1016/j.celrep.2021.109481

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0DataRank · unranked

31 citations

Jielu Hao, Mariana G. Tarragó, Gina M. Warner, Nino Giorgadze, Qing Wei +11 more

SMAD4 mutations and cross-talk between TGF-β/IFNγ signaling accelerate rates of DNA damage and cellular senescence, resulting in a segmental progeroid syndrome—the Myhre syndrome

GeroScience(2021)10.1007/s11357-020-00318-6

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0DataRank · unranked

18 citations

Deyin Hou, Jiaming Zhang, Xiaomeng Yang, Goli Compoginis, Takayasu Mori +6 more

A New Gene Set Identifies Senescent Cells and Predicts Senescence-Associated Pathways Across Tissues

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.10.472095

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0DataRank · unranked

59 citations

Robyn Laura Kosinsky, Elizabeth J. Atkinson, Madison L. Doolittle, Xu Zhang, Nathan K. LeBrasseur +14 more

Accelerated aging in older cancer survivors

Journal of the American Geriatrics Society(2021)10.1111/jgs.17461

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0DataRank · unranked

46 citations

James L. Kirkland, Tamar Tchkonia, George A. Kuchel, Mina S. Sedrak

A New Gene Set Identifies Senescent Cells and Predicts Senescence-Associated Pathways Across Tissues

Research Square(2021)10.21203/rs.3.rs-1034608/v1

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0DataRank · unranked

6 citations

Dominik Saul, Robyn Laura Kosinsky, Elizabeth J. Atkinson, Madison L. Doolittle, Xu Zhang +14 more

Cellular senescence and senolytics: the path to the clinic

Nature Medicine(2022)10.1038/s41591-022-01923-y

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0DataRank · unranked

1054 citations

Tamar Tchkonia, James L. Kirkland, Selim Chaib

A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues

Nature Communications(2022)10.1038/s41467-022-32552-1

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0DataRank · unranked

988 citations

Robyn Laura Kosinsky, Elizabeth J. Atkinson, Madison L. Doolittle, Xu Zhang, Nathan K. LeBrasseur +14 more

Rejuvenation of the aged brain immune cell landscape in mice through p16-positive senescent cell clearance

Nature Communications(2022)10.1038/s41467-022-33226-8

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0DataRank · unranked

106 citations

Vesselina Pearsall, Chase M. Carver, Elizabeth J. Atkinson, Benjamin D. Clarkson, Ethan M. Grund +24 more

BMP4 and Gremlin 1 regulate hepatic cell senescence during clinical progression of NAFLD/NASH

Nature Metabolism(2022)10.1038/s42255-022-00620-x

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0DataRank · unranked

95 citations

Aidin Rawshani, L Bonnet, Xiangyü Li, Hong Yang, Adil Mardinoğlu +8 more

Targeting cellular senescence in metabolic disease

Molecular Metabolism(2022)10.1016/j.molmet.2022.101601

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0DataRank · unranked

67 citations

Tamar Tchkonia, James L. Kirkland, Allyson K. Palmer

Palmitate induces DNA damage and senescence in human adipocytes in vitro that can be alleviated by oleic acid but not inorganic nitrate

Experimental Gerontology(2022)10.1016/j.exger.2022.111798

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0DataRank · unranked

32 citations

Tamar Tchkonia, James L. Kirkland, Mario Siervo, Gabriele Saretzki, Abbas Ishaq

Selective kidney targeting increases the efficacy of mesenchymal stromal/stem cells for alleviation of murine stenotic‐kidney senescence and damage

Journal of Tissue Engineering and Regenerative Medicine(2022)10.1002/term.3299

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0DataRank · unranked

20 citations

Kai Jiang, Xiaojun Chen, Amrutesh S. Puranik, Xiangyang Zhu, Amir Lerman +4 more

The efficacy of chemotherapy is limited by intratumoural senescent cells that persist through the upregulation of PD-L2

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.04.501681

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0DataRank · unranked

7 citations

José A López-Domínguez, Marta Lalinde-Gutiérrez, Neus Prats, Inés Marín, Kathleen Meyer +14 more

Key Elements of Cellular Senescence Involve Transcriptional Repression of Mitotic and DNA Repair Genes Through the p53-p16/pRB-E2F-DREAM Complex

Research Square(2022)10.21203/rs.3.rs-2106211/v1

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0DataRank · unranked

0 citations

Francesc Miro Mur, Jaume Alijotas‐Reig, Tamar Tchkonia, Simó Schwartz, James L. Kirkland +2 more

Senolytics dasatinib and quercetin in idiopathic pulmonary fibrosis: results of a phase I, single-blind, single-center, randomized, placebo-controlled pilot trial on feasibility and tolerability

EBioMedicine(2023)10.1016/j.ebiom.2023.104481

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0DataRank · unranked

267 citations

Dean L. Kellogg, Jaime Justice, Martin Goros, Jonathan Gelfond, Rodolfo M. Pascual +10 more

Senescent Cells: A Therapeutic Target in Cardiovascular Diseases

Cells(2023)10.3390/cells12091296

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0DataRank · unranked

105 citations

Karl H Paul, Tohru Minamino, Jordan D. Miller, Amir Lerman, Georgina M. Ellison +3 more

Local senolysis in aged mice only partially replicates the benefits of systemic senolysis

Journal of Clinical Investigation(2023)10.1172/jci162519

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0DataRank · unranked

75 citations

Dominik Saul, Madison L. Doolittle, Japneet Kaur, Jennifer L. Rowsey, Stephanie J. B. Vos +16 more

Key elements of cellular senescence involve transcriptional repression of mitotic and DNA repair genes through the p53-p16/RB-E2F-DREAM complex

Aging(2023)10.18632/aging.204743

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0DataRank · unranked

48 citations

Francesc Miró‐Mur, Jaume Alijotas‐Reig, Tamar Tchkonia, Simó Schwartz, James L. Kirkland +2 more

An untapped window of opportunity for glioma: targeting therapy-induced senescence prior to recurrence

npj Precision Oncology(2023)10.1038/s41698-023-00476-8

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0DataRank · unranked

33 citations

Lucas P. Carlstrom, Bryan J. Neth, Ian Olson, Karishma Rajani, Masum Rahman +15 more

Transplanting old organs promotes senescence in young recipients

American Journal of Transplantation(2023)10.1016/j.ajt.2023.10.013

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0DataRank · unranked

32 citations

Maximilian J. Roesel, Friederike Martin, Andreas Schroeter, Tomohisa Matsunaga, Ryoichi Maenosono +15 more

Caloric Restriction Intervention Alters Specific Circulating Biomarkers of the Senescence-Associated Secretome in Middle-Aged and Older Adults With Obesity and Prediabetes in an 18-Week Randomized Controlled Trial

The Journals of Gerontology Series A(2023)10.1093/gerona/glad214

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0DataRank · unranked

30 citations

Xiaoyan Leng, Nathan K. LeBrasseur, Tamar Tchkonia, James L. Kirkland, Natalia Mitin +5 more

Potential Clinical Implications of Senotherapies for Cardiovascular Disease

Circulation Journal(2023)10.1253/circj.cj-23-0657

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0DataRank · unranked

27 citations

Goro Katsuumi, Tamar Tchkonia, James L. Kirkland, Tohru Minamino, Masayoshi Suda

Cell senescence, the senescence-associated secretory phenotype, and cancers

PLoS Biology(2023)10.1371/journal.pbio.3002326

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0DataRank · unranked

23 citations

Tamar Tchkonia, James L. Kirkland, Larissa Prata

A chronic wound model to investigate skin cellular senescence

Aging(2023)10.18632/aging.204667

N/A

0DataRank · unranked

17 citations

Parisa Dashti, Tamar Pirtskhalava, Burak Tekin, Christina L. Inman, Lilian Sales Gomez +7 more

The efficacy of chemotherapy is limited by intratumoral senescent cells expressing PD-L2

Nature Cancer(2024)10.1038/s43018-023-00712-x

N/A

0DataRank · unranked

99 citations

José A López-Domínguez, Marta Lalinde-Gutiérrez, Neus Prats, Inés Marín, Olga Boix +18 more

Fisetin as a senotherapeutic agent: Evidence and perspectives for age-related diseases

Mechanisms of Ageing and Development(2024)10.1016/j.mad.2024.111995

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0DataRank · unranked

76 citations

Jan O. Nehlin, Morten Baltzer Houlind, Lene Juel Rasmussen, Tamar Tchkonia, James L. Kirkland +3 more

Targeting Cell Senescence and Senolytics: Novel Interventions for Age-Related Endocrine Dysfunction

Endocrine Reviews(2024)10.1210/endrev/bnae010

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0DataRank · unranked

66 citations

Karl H Paul, Utkarsh Tripathi, Tohru Minamino, Tamar Tchkonia, James L. Kirkland +1 more

Intermittent clearance of p21-highly-expressing cells extends lifespan and confers sustained benefits to health and physical function

Cell Metabolism(2024)10.1016/j.cmet.2024.07.006

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0DataRank · unranked

50 citations

Lichao Wang, Nathan Gasek, Chia‐Ling Kuo, Jia Nie, Taewan Kim +21 more

Mapping epidermal and dermal cellular senescence in human skin aging

Aging Cell(2024)10.1111/acel.14358

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0DataRank · unranked

30 citations

Clarisse Gânier, David B. Allison, Tamar Tchkonia, Sundeep Khosla, James L. Kirkland +3 more

Clearance of p21 highly expressing senescent cells accelerates cutaneous wound healing

Nature Aging(2024)10.1038/s43587-024-00755-4

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0DataRank · unranked

30 citations

Pengyi Yan, Junyu Zhu, K‐Raman Purushothaman, Taewan Kim, Lichao Wang +13 more

Senescent cell transplantation into the skin induces age‐related peripheral dysfunction and cognitive decline

Aging Cell(2024)10.1111/acel.14340

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0DataRank · unranked

26 citations

Hélène Martini, Stella Victorelli, Anthony B. Lagnado, Saranya P. Wyles, Jennifer L. Rowsey +12 more

Patients With Coronary Microvascular Dysfunction Have Less Circulating α‐Klotho

Journal of the American Heart Association(2024)10.1161/jaha.123.031972

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0DataRank · unranked

18 citations

Ilke Ӧzcan, Rajiv Gulati, Abhiram Prasad, Tamar Tchkonia, James L. Kirkland +4 more

Endothelial senescent-cell-specific clearance alleviates metabolic dysfunction in obese mice

Cell Metabolism(2025)10.1016/j.cmet.2025.10.009

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0DataRank · unranked

13 citations

Selim Chaib, Larissa Prata, Yi Zhu, Utkarsh Tripathi, Karl H Paul +21 more

Senolytic‐Resistant Senescent Cells Have a Distinct SASP Profile and Functional Impact: The Path to Developing Senosensitizers

Aging Cell(2025)10.1111/acel.70358

N/A

0DataRank · unranked

6 citations

Masayoshi Suda, Vagisha Kulshreshtha, Bryan T Piatkowski, Allyson K. Palmer, Nino Giorgadze +17 more

Cellular senescence promotes macrophage-to-myofibroblast transition in chronic ischemic renal disease

Cell Death and Disease(2025)10.1038/s41419-025-07666-1

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0DataRank · unranked

12 citations

Xiangyang Zhu, Wenqi Ma, Ying Zhang, Fei Yuan, Seo Rin Kim +7 more

Pharmacological clearance of senescent cells reduces inflammation, endothelial damage and cardiac fibrosis in HFpEF

Cardiovascular Research(2025)10.1093/cvr/cvaf208

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0DataRank · unranked

5 citations

Inês Tomé, Francisco Vasques-Nóvoa, Glória Conceição, Andreia Silva, António S. Barros +23 more

Senotherapeutics for metabolic disease and diabetic complications

Journal of Internal Medicine(2025)10.1111/joim.70039

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0DataRank · unranked

2 citations

Rosa Spinelli, Larissa Prata, Selim Chaib, Masayoshi Suda, Tamar Tchkonia +3 more

Space radiation induces distinct senescent phenotypes: Implications for space travel

npj Aging(2025)10.1038/s41514-025-00272-7

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0DataRank · unranked

1 citations

Bipasha Mukherjee, Ashley M. Saathoff, Zachary A. Eduvas, Joshua Bartz, Xu Zhang +10 more

A human and mouse subpopulation of senescent β-cells induces pathologic dysfunction through targetable paracrine signaling

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.07.648438

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0DataRank · unranked

0 citations

Priscila Carapeto, Cristian Abarca, Francesko Hela, Stephanie Sanjines, Sebastian Pena +20 more

Senolytic-Resistant Senescent Cells Have a Distinct SASP Profile and Functional Impact: The Path to Developing Senosensitizers

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.27.672709

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0DataRank · unranked

0 citations

Masayoshi Suda, Vagisha Kulshreshtha, Bryan Piatkowski, Allyson K. Palmer, Nino Giorgadze +17 more

Senolytics prevent mt-DNA-induced inflammation and promote the survival of aged organs following transplantation

Nature Communications(2020)10.1038/s41467-020-18039-x

N/A

0DataRank · unranked

199 citations

Midas Seyda, Timm Heinbokel, Ryoichi Maenosono, Koichiro Minami, Yeqi Nian +11 more

Reducing Senescent Cell Burden in Aging and Disease

Trends in Molecular Medicine(2020)10.1016/j.molmed.2020.03.005

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0DataRank · unranked

188 citations

João F. Passos, Sundeep Khosla, Tamar Tchkonia, James L. Kirkland, Robert J. Pignolo

Human Obesity Induces Dysfunction and Early Senescence in Adipose Tissue-Derived Mesenchymal Stromal/Stem Cells

Frontiers in Cell and Developmental Biology(2020)10.3389/fcell.2020.00197

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0DataRank · unranked

171 citations

LaTonya J. Hickson, Todd A. Kellogg, Travis J. McKenzie, Julie K. Heimbach, Timucin Taner +10 more

Targeted Reduction of Senescent Cell Burden Alleviates Focal Radiotherapy-Related Bone Loss

Journal of Bone and Mineral Research(2020)10.1002/jbmr.3978

N/A

0DataRank · unranked

139 citations

Anthony B. Lagnado, Joshua N. Farr, David G. Monroe, Sean S. Park, Christine Hachfeld +6 more

Senolytic Drugs: Reducing Senescent Cell Viability to Extend Health Span

The Annual Review of Pharmacology and Toxicology(2020)10.1146/annurev-pharmtox-050120-105018

N/A

0DataRank · unranked

317 citations

Diana Jurk, Sundeep Khosla, James L. Kirkland, Nathan K. LeBrasseur, Jordan D. Miller +5 more

Targeting Senescent Cells for a Healthier Aging: Challenges and Opportunities

Advanced Science(2020)10.1002/advs.202002611

N/A

0DataRank · unranked

131 citations

Tamar Tchkonia, Jing Jiang, James L. Kirkland, Yu Sun, Shuling Song

New Horizons: Novel Approaches to Enhance Healthspan Through Targeting Cellular Senescence and Related Aging Mechanisms

The Journal of Clinical Endocrinology & Metabolism(2020)10.1210/clinem/dgaa728

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0DataRank · unranked

126 citations

Allyson K. Palmer, James L. Kirkland, Tamar Tchkonia

Transplanting cells from old but not young donors causes physical dysfunction in older recipients

Aging Cell(2020)10.1111/acel.13106

N/A

0DataRank · unranked

80 citations

Zukai Liu, Vicky P. Chen, Lichao Wang, Christina L. Inman, Yueying Zhou +8 more

Increased cellular senescence in the murine and human stenotic kidney: Effect of mesenchymal stem cells

Journal of Cellular Physiology(2020)10.1002/jcp.29940

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0DataRank · unranked

47 citations

Xiangyu Zou, Hui Tang, Amrutesh S. Puranik, Abdelrhman Abumoawad, Xiangyang Zhu +6 more

Mechanisms of vascular dysfunction in the interleukin-10–deficient murine model of preeclampsia indicate nitric oxide dysregulation

Kidney International(2020)10.1016/j.kint.2020.09.034

N/A

0DataRank · unranked

23 citations

Karl A. Nath, Sonja Šuvakov, Oscar A. Garcia Valencia, Santosh Parashuram, Wendy White +14 more

Whole‐body senescent cell clearance alleviates age‐related brain inflammation and cognitive impairment in mice

Aging Cell(2021)10.1111/acel.13296

N/A

0DataRank · unranked

409 citations

Shane A. Evans, Edward Fielder, Stella Victorelli, Patrick Krüger, Hanna Salmonowicz +18 more

Neutrophils induce paracrine telomere dysfunction and senescence in ROS‐dependent manner

The EMBO Journal(2021)10.15252/embj.2020106048

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0DataRank · unranked

212 citations

Jack Leslie, Marie‐Hélène Ruchaud‐Sparagano, Stella Victorelli, Petra Hirsova, Mikołaj Ogrodnik +32 more

Targeting p21Cip1 highly expressing cells in adipose tissue alleviates insulin resistance in obesity

Cell Metabolism(2021)10.1016/j.cmet.2021.11.002

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0DataRank · unranked

166 citations

Binsheng Wang, Nathan Gasek, Yueying Zhou, Rachel Cohn, Dominique E. Martin +21 more

Impact of Senescent Cell Subtypes on Tissue Dysfunction and Repair: Importance and Research Questions

Mechanisms of Ageing and Development(2021)10.1016/j.mad.2021.111548

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0DataRank · unranked

101 citations

Avanish Misra, Tamar Tchkonia, James L. Kirkland, Utkarsh Tripathi

Strategies for late phase preclinical and early clinical trials of senolytics

Mechanisms of Ageing and Development(2021)10.1016/j.mad.2021.111591

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0DataRank · unranked

98 citations

Avanish Misra, Jair Machado Espindola Netto, Tamar Tchkonia, James L. Kirkland, Erin O. Wissler Gerdes

SARS-CoV-2 causes senescence in human cells and exacerbates the senescence-associated secretory phenotype through TLR-3

Aging(2021)10.18632/aging.203560

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0DataRank · unranked

88 citations

Rayhane Nchioua, Larissa Prata, Yi Zhu, Erin O. Wissler Gerdes, Nino Giorgadze +14 more

Partial inhibition of mitochondrial complex I ameliorates Alzheimer’s disease pathology and cognition in APP/PS1 female mice

Communications Biology(2021)10.1038/s42003-020-01584-y

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0DataRank · unranked

69 citations

Sergey Trushin, Anthony Sheu, Layla Khalili, Su-Youne Chang, Xing Li +31 more

Quercetin Reverses Cardiac Systolic Dysfunction in Mice Fed with a High‐Fat Diet: Role of Angiogenesis

Oxidative Medicine and Cellular Longevity(2021)10.1155/2021/8875729

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0DataRank · unranked

55 citations

Seo Rin Kim, Kai Jiang, Mikołaj Ogrodnik, Xiang Zhu, Christopher M. Ferguson +5 more

Senolytics: Potential for Alleviating Diabetes and Its Complications

Endocrinology(2021)10.1210/endocr/bqab058

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0DataRank · unranked

49 citations

Tamar Tchkonia, James L. Kirkland, Allyson K. Palmer