Alison D. Axtman

University of North Carolina at Chapel Hill

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 2%percentile

3.0Author DataRank

Indexed papers

4in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 4 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification

International Journal of Molecular Sciences(2021)10.3390/ijms22020566

Top 11%

1.9DataRank

Top 11%110 citations

Hassan Al‐Ali, David Andrews, Christopher R. M. Asquith, Alison D. Axtman, Ivan Đikić +25 more

Papers

Driven by 50 papers — median percentile 57. Top paper: “The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification”.

The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification

International Journal of Molecular Sciences(2021)10.3390/ijms22020566

Top 11%

1.9DataRank

Top 11%110 citations

Hassan Al‐Ali, David Andrews, Christopher R. M. Asquith, Alison D. Axtman, Ivan Đikić +25 more

Illuminating function of the understudied druggable kinome

Drug Discovery Today(2024)10.1016/j.drudis.2024.103881

N/A

0.669DataRank · unranked

17 citations

Alison D. Axtman, Timothy M. Willson, Michael B. Major, Reid Townsend, Peter K. Sorger +2 more

PKIS deep dive yields a chemical starting point for dark kinases and a cell active BRSK2 inhibitor

Scientific Reports(2020)10.1038/s41598-020-72869-9

Top 31%

0.648DataRank

Top 31%18 citations

David H. Drewry, Carrow I. Wells, Michael B. Major, Alison D. Axtman, Tigist Y. Tamir

Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin-dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology

eLife(2023)10.7554/elife.88206

N/A

0.535DataRank · unranked

15 citations

Margaux Silvestre, Carrow I. Wells, Jennifer L. Sanderson, Carla A. Ferrer, Han Wee Ong +14 more

Host Kinase CSNK2 is a Target for Inhibition of Pathogenic SARS-like β-Coronaviruses

ACS Chemical Biology(2022)10.1021/acschembio.2c00378

N/A

0.505DataRank · unranked

28 citations

Rebekah J. Dickmander, Armin Bayati, Sharon Taft-Benz, Jeffery L. Smith, Carrow I. Wells +12 more

Optimization of 3-Cyano-7-cyclopropylamino-pyrazolo[1,5- a ]pyrimidines toward the Development of an In Vivo Chemical Probe for CSNK2A

ACS Omega(2023)10.1021/acsomega.3c05377

N/A

0.442DataRank · unranked

18 citations

Han Wee Ong, Rebekah J. Dickmander, Jeffery L. Smith, Joshua B. Brown, William C. Tao +5 more

Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective

ACS Chemical Neuroscience(2023)10.1021/acschemneuro.3c00135

N/A

0.385DataRank · unranked

12 citations

Yi Liang, William Richardson, Emily R. Lowry, Carrow I. Wells, Xiangrong Chen +11 more

CK2 Chemical Probes: Past, Present, and Future

Kinases and Phosphatases(2023)10.3390/kinasesphosphatases1040017

N/A

0.373DataRank · unranked

11 citations

David H. Drewry, Alison D. Axtman, Han Wee Ong

AD Informer Set: Chemical tools to facilitate Alzheimer's disease drug discovery

Alzheimer s & Dementia Translational Research & Clinical Interventions(2022)10.1002/trc2.12246

Top 55%

0.303DataRank

Top 55%5 citations

Joel K. Annor‐Gyamfi, Jeffrey Aubé, Shaoyou Chu, Ivie L. Conlon, Kevin J. Frankowski +20 more

Modulation of Tau Tubulin Kinases (TTBK1 and TTBK2) Impacts Ciliogenesis

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.06.490937

N/A

0.241DataRank · unranked

4 citations

Ariana Marquez Gonzalez, A. Chaikuad, Stefanie Howell, Andrea S. Dunn, Alvaro A. Beltran +5 more

SGC-CK2-1: The First Selective Chemical Probe for the Pleiotropic Kinase CK2

ChemRxiv(2020)10.26434/chemrxiv.12296180.v1

N/A

0.241DataRank · unranked

4 citations

David H. Drewry, Julie E. Pickett, Alison D. Axtman, Carrow I. Wells

BRSK2 plays a role in autophagy and cancer cell growth and survival under nutrient deprivation stress via the PIK3C3 pathway

Scientific Reports(2025)10.1038/s41598-025-24354-4

N/A

0.208DataRank · unranked

3 citations

Alison D. Axtman, Rongrong Wu, Lydia J. B. Redman, Kazuaki Takabe, Aimee Stablewski +7 more

Strategic Fluorination to Achieve a Potent, Selective, Metabolically Stable, and Orally Bioavailable Inhibitor of CSNK2

Molecules(2024)10.3390/molecules29174158

N/A

0.165DataRank · unranked

2 citations

Xuan Yang, Jeffery L. Smith, Sharon Taft-Benz, Stefanie Howell, Rebekah J. Dickmander +12 more

Identification and Utilization of a Chemical Probe to Interrogate the Roles of PIKfyve in the Lifecycle of β-Coronaviruses

ChemRxiv(2022)10.26434/chemrxiv-2022-bj274

N/A

0.165DataRank · unranked

2 citations

Frances Potjewyd, Jeffrey L. Smith, Rebekah J. Dickmander, Armin Bayati, Stefanie Howell +7 more

PKIS Deep Dive Yields a Chemical Starting Point for Dark Kinases and a Cell Active BRSK2 Inhibitor

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.15.153072

Top 78%

0.104DataRank

Top 78%1 citations

David H. Drewry, Carrow I. Wells, Michael B. Major, Alison D. Axtman, Tigist Y. Tamir

SGC-CK2-1: The First Selective Chemical Probe for the Pleiotropic Kinase CK2

ChemRxiv(2020)10.26434/chemrxiv.12296180

N/A

0.104DataRank · unranked

1 citations

David H. Drewry, Julie E. Pickett, Alison D. Axtman, Carrow I. Wells

Optimization of 3-Cyano-7-cyclopropylamino-pyrazolo[1,5-a]pyrimidines Toward the Development of an In Vivo Chemical Probe for CSNK2A

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.15.540828

N/A

0DataRank · unranked

4 citations

Han Wee Ong, Rebekah J. Dickmander, Jeffery L. Smith, Joshua B. Brown, William C. Tao +5 more

Discovery and Optimization of Narrow Spectrum Inhibitors of Tousled Like Kinase 2 (TLK2) Using Quantitative Structure Activity Relationships

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.28.573261

N/A

0DataRank · unranked

1 citations

Michael P. East, Tuomo Laitinen, Carla Alamillo‐Ferrer, Erkka Hartikainen, Carrow I. Wells +7 more

Editorial: The next generation of tools and technologies for studying human neurons in a dish

Frontiers in Cellular Neuroscience(2023)10.3389/fncel.2023.1196543

N/A

0DataRank · unranked

0 citations

Alison D. Axtman, Thomas M. Durcan

Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.24.538049

N/A

0DataRank · unranked

0 citations

Margaux Silvestre, Carrow I. Wells, Jennifer L. Sanderson, Carla A. Ferrer, Han Wee Ong +14 more

Editorial: The next generation of tools and technologies for studying human neurons in a dish

UNC Libraries(2023)10.17615/frqg-vk25

N/A

0DataRank · unranked

0 citations

Alison D. Axtman, Thomas M. Durcan

More than an Amide Bioisostere: Discovery of 1,2,4-Triazole-containing Pyrazolo[1,5- a ]pyrimidine Host CSNK2 Inhibitors for Combatting β-Coronavirus Replication

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c00962

N/A

0DataRank · unranked

18 citations

Xuan Yang, Jeffery L. Smith, Rebekah J. Dickmander, Jason W. Brown, Tammy M. Havener +13 more

Illumination of understudied ciliary kinases

Frontiers in Molecular Biosciences(2024)10.3389/fmolb.2024.1352781

N/A

0DataRank · unranked

9 citations

Peter Rosston, Cecilia Rocha, Brian Anderson, Jacob L. Capener, Thomas M. Durcan +4 more

Targeting Nav1.7 and Nav1.8 with a PIKfyve inhibitor to reverse inflammatory and neuropathic pain

Neurobiology of Pain(2024)10.1016/j.ynpai.2024.100174

N/A

0DataRank · unranked

4 citations

Santiago Loya‐López, Sophia M. Min, Aida Calderón‐Rivera, Kimberly Gómez, Rajesh Khanna +2 more

Discovery and optimization of narrow spectrum inhibitors of Tousled like kinase 2 (TLK2) using quantitative structure activity relationships

European Journal of Medicinal Chemistry(2024)10.1016/j.ejmech.2024.116357

N/A

0DataRank · unranked

3 citations

Michael P. East, Tuomo Laitinen, Carla Alamillo‐Ferrer, Erkka Hartikainen, Carrow I. Wells +7 more

Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2

ACS Medicinal Chemistry Letters(2024)10.1021/acsmedchemlett.4c00219

N/A

0DataRank · unranked

1 citations

Sophia M. Min, Xiangrong Chen, Stefanie Howell, Caroline H. Rinderle, Gabriel Morel +9 more

Synthesis of 5-Benzylamino and 5-Alkylamino-Substituted Pyrimido[4,5-c]quinoline Derivatives as CSNK2A Inhibitors with Antiviral Activity

Pharmaceuticals(2024)10.3390/ph17030306

N/A

0DataRank · unranked

4 citations

Jeffery L. Smith, Rebekah J. Dickmander, Nathaniel J. Moorman, James Wellnitz, Konstantin I. Popov +3 more

More than an Amide Bioisostere: Discovery of 1,2,4-Triazole-containing Pyrazolo[1,5-a]pyrimidine Host CSNK2 Inhibitors for Combatting β-Coronavirus Replication

ChemRxiv(2024)10.26434/chemrxiv-2024-h2x2b

N/A

0DataRank · unranked

0 citations

Xuan Yang, Jeffery L. Smith, Rebekah J. Dickmander, Joshua B. Brown, Tammy M. Havener +13 more

Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.05.12.593776

N/A

0DataRank · unranked

0 citations

Sophia M. Min, Xiangrong Chen, Stefanie Howell, Caroline H. Rinderle, Gabriel Morel +9 more

Application of Integrated Drug Screening/Kinome Analysis to Identify Inhibitors of Gemcitabine-Resistant Pancreatic Cancer Cell Growth

UNC Libraries(2024)10.17615/jadh-1012

N/A

0DataRank · unranked

0 citations

Laura E. Herring, Alison D. Axtman, Michael P. East, Benjamin Lee, Denis O. Okumu +12 more

Targeting Nav1.7 and Nav1.8 with a PIKfyve inhibitor to Reverse inflammatory and neuropathic pain

UNC Libraries(2024)10.17615/dyhg-n602

N/A

0DataRank · unranked

0 citations

Sophia M. Min, Erick J. Rodríguez‐Palma, Alison D. Axtman, Kimberly Gómez, Aida Calderón‐Rivera +2 more

Development of a Second-Generation, In Vivo Chemical Probe for PIKfyve

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.4c02531

N/A

0DataRank · unranked

9 citations

Frances M. Bashore, Jeffrey L. Smith, Tammy M. Havener, Stefanie Howell, Haoxi Li +4 more

Cellular Context Influences Kinase Inhibitor Selectivity

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.09.681452

N/A

0DataRank · unranked

1 citations

Frances M. Bashore, Kaitlin K. Dunn Hoffman, Cameron Daamgard, Michael R. Slater, David H. Drewry +3 more

Development of a chemical probe to enable characterization of the casein kinase 1γ subfamily

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.10.675406

N/A

0DataRank · unranked

0 citations

Thomas Krämer, Frances M. Bashore, E Flory, F. Li, Blair L. Strang +2 more

PAK1 inhibitor NVS‐PAK1‐1 preserves dendritic spines in amyloid/tau exposed neurons and 5xFAD mice

Alzheimer s & Dementia(2025)10.1002/alz.71033

N/A

0DataRank · unranked

0 citations

Hasi Huhe, Sean-Paul G. Williams, Sukhneet Kaur, Yeonglong Albert Ay, Zachary W. Davis‐Gilbert +20 more

Defining the Neural Kinome: Strategies and Opportunities for Small Molecule Drug Discovery to Target Neurodegenerative Diseases

ACS Chemical Neuroscience(2020)10.1021/acschemneuro.0c00176

N/A

0DataRank · unranked

36 citations

Carrow I. Wells, David H. Drewry, Lenore K. Beitel, Thomas M. Durcan, Alison D. Axtman +1 more

Towards a RIOK2 chemical probe: cellular potency improvement of a selective 2-(acylamino)pyridine series

RSC Medicinal Chemistry(2020)10.1039/d0md00292e

N/A

0DataRank · unranked

5 citations

Álvaro Lorente‐Macías, Carrow I. Wells, Julie E. Pickett, Alfredo Picado, William J. Zuercher +2 more

Development of a potent and selective chemical probe for the pleiotropic kinase CK2

Cell chemical biology(2021)10.1016/j.chembiol.2020.12.013

N/A

0DataRank · unranked

113 citations

David H. Drewry, Julie E. Pickett, Amelie Tjaden, Andreas Krämer, Susanne Müller +6 more

Exploration of Aberrant E3 Ligases Implicated in Alzheimer’s Disease and Development of Chemical Tools to Modulate Their Function

Frontiers in Cellular Neuroscience(2021)10.3389/fncel.2021.768655

N/A

0DataRank · unranked

40 citations

Alison D. Axtman, Frances Potjewyd

Identification of Pyrimidine-Based Lead Compounds for Understudied Kinases Implicated in Driving Neurodegeneration

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.1c00440

N/A

0DataRank · unranked

33 citations

Joel K. Annor‐Gyamfi, Carrow I. Wells, Julie E. Pickett, Verena Dederer, Franziska Preuß +3 more

Strategy for Lead Identification for Understudied Kinases

ChemRxiv(2021)10.26434/chemrxiv.14195207.v1

N/A

0DataRank · unranked

0 citations

Joel K. Annor‐Gyamfi, Carrow I. Wells, Julie E. Pickett, Alison D. Axtman, David H. Drewry

Strategy for Lead Identification for Understudied Kinases

ChemRxiv(2021)10.26434/chemrxiv.14195207

N/A

0DataRank · unranked

0 citations

Joel K. Annor‐Gyamfi, Carrow I. Wells, Julie E. Pickett, Alison D. Axtman, David H. Drewry

Evaluation of a Selective Chemical Probe Validates That CK2 Mediates Neuroinflammation in a Human Induced Pluripotent Stem Cell-Derived Microglial Model

Frontiers in Molecular Neuroscience(2022)10.3389/fnmol.2022.824956

N/A

0DataRank · unranked

22 citations

C. Kinoshita, Alison D. Axtman, Jessica E. Young, Swati Mishra

Protein proximity networks and functional evaluation of the casein kinase 1 gamma family reveal unique roles for CK1γ3 in WNT signaling

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.101986

N/A

0DataRank · unranked

11 citations

Frances Potjewyd, Brittany M. Bowman, Smaranda Solomon, Kyle M. LaPak, Dhaval P. Bhatt +5 more

Evaluation of a Selective Chemical Probe Validates That CK2 Mediates Neuroinflammation in a Human Induced Pluripotent Stem Cell-Derived Mircroglial Model

UNC Libraries(2022)10.17615/8hq9-qz39

N/A

0DataRank · unranked

0 citations

Jessica E. Young, Swati Mishra, Alison D. Axtman, C. Kinoshita

Identification of a chemical probe for lipid kinase phosphatidylinositol-5-phosphate 4-kinase gamma (PI5P4Kγ)

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.08.507203

N/A

0DataRank · unranked

0 citations

Frances Potjewyd, Jeffery L. Smith, Stefanie Howell, Alison D. Axtman, David H. Drewry

Identification and Utilization of a Chemical Probe to Interrogate the Roles of PIKfyve in the Lifecycle of β-Coronaviruses

UNC Libraries(2022)10.17615/cph0-4s39

N/A

0DataRank · unranked

0 citations

Sharon Taft-Benz, Nathaniel J. Moorman, Peter S. McPherson, Alison D. Axtman, David H. Drewry +8 more

Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis

Scientific Reports(2023)10.1038/s41598-023-32854-4

N/A

0DataRank · unranked

20 citations

Ariana Marquez Gonzalez, A. Chaikuad, Stefanie Howell, Andrea S. Dunn, Alvaro A. Beltran +5 more

Discovery of a Potent and Selective Naphthyridine-Based Chemical Probe for Casein Kinase 2

ACS Medicinal Chemistry Letters(2023)10.1021/acsmedchemlett.2c00530

N/A

0DataRank · unranked

16 citations

Andreas Krämer, James E. Dunford, Stefanie Howell, Filiz Senbabaoglu, Carrow I. Wells +8 more

Comparison of CX-4945 and SGC-CK2-1 as inhibitors of CSNK2 using quantitative phosphoproteomics: Triple SILAC in combination with inhibitor-resistant CSNK2

Current Research in Chemical Biology(2023)10.1016/j.crchbi.2023.100041

N/A

0DataRank · unranked

13 citations

Laszlo Gyenis, Kristina Jurčić, Scott E. Roffey, Aakshi Puri, Predrag Jovanović +8 more

Alison D. Axtman

Indexed papers

Top data-sharing exemplar

Papers