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Shape shifting: The multiple conformational substates of the PTEN N‐terminal PIP2‐binding domain

Protein Science(2022)10.1002/pro.4308Source: DataRank Database

Shape shifting: The multiple conformational substates of the PTEN N‐terminal PIP2‐binding domain is a research paper published in Protein Science (2022). On theSindex it has a DataRank of 0. It has been cited 13 times.

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Open Access13 citations

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Enrichment:Funding (16 grants)OA: hybridTopics (24)IDs (PubMed, PMC)Annotations (1)SDGs (1)

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Authors (6)

Iris Nira Smith ORCID,William R. Martin ORCID,Krishnendu Khan ORCID,Feixiong Cheng ORCID,Charis Eng ORCID

Live enrichment

PubMed:35481646 PMC:PMC9004235

National Institute of General Medical Sciences

Grant: 1K99GM143552‐01

National Institute on Aging

Grant: R01AG066707

National Institute on Aging

Grant: U01AG073323

National Institutes of Health

Grant: 1S10OD023436‐01

NIGMS NIH HHS

Grant: 1K99GM143552-01

NIH HHS

Grant: 1S10OD023436-01

High-End Instrumentation (HEI) Grant Program (S10)

NIH HHS

Grant: S10 OD023436

NIGMS NIH HHS

Grant: K99 GM143552

National Institutes of Health

Grant: 5U01AG073323-05

Alzheimer's MultiOme Data Repurposing: Artificial Intelligence, Network Medicine, and Therapeutics Discovery

European Commission

Grant: 777536

Integrating and managing services for the European Open Science Cloud

National Institutes of Health

Grant: 5K99GM143552-02

Unraveling the PTEN Interactome: Modeling Structural and Functional Dynamic Network Architecture for Therapeutic Modulation in Cancer and Autism

European Commission

Grant: 261572

A worldwide e-Infrastructure for NMR and structural biology

European Commission

Grant: 675858

World-wide E-infrastructure for structural biology

European Commission

Grant: 101017567

EGI Advanced Computing for EOSC

National Institutes of Health

Grant: 5R01AG066707-04

Endophenotype Network-based Approaches to Prediction and Population-based Validation of in Silico Drug Repurposing for Alzheimers Disease

Ambrose Monell Foundation

hybridLicense: cc-by-nc-nd

publisherhttps://doi.org/10.1002/pro.4308

publisherhttps://onlinelibrary.wiley.com/doi/pdf/10.1002/pro.4308

publisherhttps://onlinelibrary.wiley.com/doi/full-xml/10.1002/pro.4308

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/9004235

Europe_PMChttps://europepmc.org/articles/PMC9004235

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences0103 physical sciences01 natural sciences

MeSH Terms

LipidsSignal TransductionCell ProliferationPhosphatidylinositol 3-KinasesMolecular Docking Simulation

Keywords

Molecular dockingPTENMolecular Dynamics SimulationsResidue Interaction NetworkCrosslinking Mass SpectrometryIntegrative Structural ModelingAlphafoldRosettafoldMolecular Docking SimulationPhosphatidylinositol 3-KinasesAccelerated CommunicationsLipidsCell ProliferationSignal Transduction

Sustainable Development Goals

SDG 3: 3. Good health