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Structure activity relationship of 3-nitro-2-(trifluoromethyl)-2H-chromene derivatives as P2Y6 receptor antagonists

Bioorganic & Medicinal Chemistry Letters(2021)10.1016/j.bmcl.2021.128008Source: DataRank Database

Structure activity relationship of 3-nitro-2-(trifluoromethyl)-2H-chromene derivatives as P2Y6 receptor antagonists is a research paper published in Bioorganic & Medicinal Chemistry Letters (2021). On theSindex it has a DataRank of 0.449. It has been cited 19 times.

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0.449DataRank · unranked

Scored on demand from live citation data

Open Access19 citations
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›Methodology & internals
datarank_citation_only_1hop_v6· scope data_onlyMethodology
Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring
Enrichment:Funding (2 grants)Impact (FWCI 2.06)OA: greenTopics (30)IDs (PubMed, OpenAlex)

FAIR Checklist

Context only (not used in score)
Findable (1/2)
  • Has DOI
Accessible (1/2)
  • Open Access
Interoperable (0/2)
    Reusable (0/3)

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      DataRank Breakdown

      Base Score 100%Citation Network 0%

      Base Score Contribution

      0.449

      From this paper's citation signal

      Citation Network Contribution

      0

      Citation network not refreshed for this result

      This paper's DataRank is currently driven only by its base citation score. Citation network data was not refreshed for this result.

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      Authors (6)

      Shanu JainORCID,Varun GopinatthORCID,Ngan B. PhungORCID,Zhan‐Guo GaoORCID,Kenneth A. JacobsonORCID
      Live enrichment
      PubMed:33831560OpenAlex:https://openalex.org/W3149954020

      National Institute of Diabetes and Digestive and Kidney Diseases

      Grant: HHSN-271-2008-00025-C

      National Institute of Diabetes and Digestive and Kidney Diseases

      Grant: ZIADK31116

      FWCI

      2.06

      Citation Percentile

      0.8%

      Citation Trend

      2021
      2022
      2023
      2024
      2025
      2026

      greenLicense: https://www.elsevier.com/legal/tdmrep-license
      repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8240625
      repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8240625
      publisherhttps://api.elsevier.com/content/article/PII:S0960894X21002341?httpAccept=text/xml
      publisherhttps://api.elsevier.com/content/article/PII:S0960894X21002341?httpAccept=text/plain
      journalhttps://doi.org/10.1016/j.bmcl.2021.128008

      Fields of Study

      Adenosine and Purinergic SignalingNitric Oxide and Endothelin EffectsSynthesis and Catalytic Reactions

      MeSH Terms

      BenzopyransDose-Response Relationship, DrugHumansStructure-Activity RelationshipMolecular StructureReceptors, Purinergic P2Purinergic P2Y Receptor Antagonists

      Keywords

      ChemistryBioisostereTrifluoromethylStereochemistryNitroArylAmidineLigand (biochemistry)Sonogashira couplingChemical synthesisSteric effectsAgonistCarboxylateCarboxylic acidAlkylReceptorIn vitroBiochemistryPalladiumOrganic chemistry

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