🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Fostering Data Sharing

Search Papers Authors Institutions Grants FAIR About

TheSindex

Fostering Data Sharing

Empowering the data sharing that empowers science — an open, citation-grounded index for datasets.

Product

Search
API
Explore
Rankings

Resources

Methodology
Data Sources
Documentation
Press

Organization

About
Team
Wikidata

© 2026 theSindex. All rights reserved.

Home
Papers
Structure and mechanism of human cystine exporter cystinosin

Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

Structure and mechanism of human cystine exporter cystinosin

Cell(2022)10.1016/j.cell.2022.08.020Source: DataRank Database

Structure and mechanism of human cystine exporter cystinosin is a research paper published in Cell (2022). On theSindex it has a DataRank of 0. It has been cited 50 times.

N/A

0DataRank · unranked

Scored on demand from live citation data

Open Access50 citations

Cite:

Linked data & code

gen cellosaurus uniprot pdb

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (38 grants)Impact (FWCI 5.46)OA: greenTopics (49)IDs (PubMed, PMC, OpenAlex)Annotations (4)

FAIR Checklist

Context only (not used in score)

FFindable (1/2)

Has DOI

AAccessible (1/2)

Open Access

IInteroperable (0/2)

RReusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

Run a calibrated FAIR evaluation for this paper →

We only score data papers we can read in full — never from an abstract alone.

Authors (12)

Philip Schmiege ORCID,Tufa E. Assafa ORCID,Rong Wang ORCID,Yan Xu ORCID,Linda Donnelly ORCID

Live enrichment

PubMed:36113465 PMC:PMC9530027 OpenAlex:https://openalex.org/W4295960241

National Institute of General Medical Sciences

Grant: S10OD024980

National Institute of General Medical Sciences

Grant: AGM-12006

National Institute of General Medical Sciences

Grant: P30GM138396

National Institute of General Medical Sciences

Grant: P30GM133894

National Institute of General Medical Sciences

Grant: R01 GM117108

G. Harold and Leila Y. Mathers Charitable Foundation

Grant: R01 GM135343

G. Harold and Leila Y. Mathers Charitable Foundation

Grant: P01 HL160487

G. Harold and Leila Y. Mathers Charitable Foundation

Grant: R35GM131781

American Pain Society

Grant: 12-2

Cancer Prevention and Research Institute of Texas

Grant: RP170644

Argonne National Laboratory

Grant: DE-AC02-06CH11357

Basic Energy Sciences

Grant: DE-AC02-76SF00515

National Cancer Institute

Grant: ACB-12002

Welch Foundation

Grant: I-1957

Welch Foundation

Grant: T32GM131963

National Institutes of Health

Grant: RR029205

National Institutes of Health

Grant: GM124165

National Institutes of Health

Grant: OD021527

National Institutes of Health

Grant: S10 OD012289

NIGMS NIH HHS

Grant: P30 GM124165

NCRR NIH HHS

Grant: S10 RR029205

NIH HHS

Grant: S10 OD021527

National Institutes of Health

Grant: 5R01GM117108-04

Structure and Function of SWEET Sugar Transporters

National Institutes of Health

Grant: 5R35GM131781-03

Discovering How Cu(II)/Zn(II) Uptake by the Prion Protein Controls Structure, Function and Neurotoxicity

National Institutes of Health

Grant: 3P30GM124165-03S1

NE-CAT: A Resource for Advanced Macromolecular Crystallography

National Institutes of Health

Grant: 5T32GM131963-04

Molecular Biophysics Training Program

National Institutes of Health

Grant: 1P01HL160487-01

New Approaches to Reduce Residual Cardiovascular Risk

National Institutes of Health

Grant: 5F32GM012006-03

MOLECULAR GENETIC ANALYSIS OF THE DROSOPHILA 205K MAP

National Institutes of Health

Grant: 3P30GM133894-06S1

A Synchrotron Radiation Structural Biology Resource

National Institutes of Health

Grant: 1S10OD024980-01

Upgrade of a Pulsed Electron Paramagnetic Resonance Spectrometer

National Institutes of Health

Grant: 5R01GM135343-03

Structural and Functional investigations of Hedgehog Signaling Transduction

National Institutes of Health

Grant: 1S10OD012289-01A1

High-Speed High-Sensitivity Detector for X-ray Micro-Crystallography at GM/CA@APS

Biological and Environmental Research

Cystinosis Research Foundation

Stanford University

U.S. Department of Energy

Office of Science

National Heart, Lung, and Blood Institute

FWCI

5.46

Citation Percentile

1.0%

Citation Trend

2022

2023

2024

2025

2026

greenLicense: Elsevier Non-Commercial

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/9530027

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/9530027

publisherhttps://api.elsevier.com/content/article/PII:S009286742201114X?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S009286742201114X?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.cell.2022.08.020

Fields of Study

Biomedical Research and PathophysiologyNeonatal Health and BiochemistryAmino Acid Enzymes and Metabolism0301 basic medicine0303 health sciences03 medical and health sciencesAmino Acid Transport SystemsCysteineCystineHumansLysosomesProtonsTOR Serine-Threonine Kinases

MeSH Terms

CysteineCystineHumansLysosomesProtonsAmino Acid Transport SystemsTOR Serine-Threonine Kinases

Keywords

BiologyBiochemistryAmino acidCytosolTransporterCystineCysteineEffluxCell biologyProtonationEnzymeChemistryGeneX-ray crystallographyDeerCystinosisKeywordsLysosomal Storage DiseaseCryo-emMembrane Protein DynamicsLysosomal TransporterCystinosinFast AdaptationRagulator-rag ComplexAmino Acid Transport SystemsTOR Serine-Threonine KinasesHumansProtonsLysosomes

Related Papers (10)

In vivo CRISPR screening reveals nutrient signaling processes underpinning CD8+ T cell fate decisions

Cell(2021)

co-citedsame journal

10.1016/j.cell.2021.02.021

LRRK2 mediates tubulation and vesicle sorting from lysosomes

Science Advances(2020)

co-cited

10.1126/sciadv.abb2454

Maintaining Iron Homeostasis Is the Key Role of Lysosomal Acidity for Cell Proliferation

Molecular Cell(2020)

co-cited

10.1016/j.molcel.2020.01.003

NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis and Is a Targetable Pathway in Niemann-Pick Type C

Developmental Cell(2020)

co-cited

10.1016/j.devcel.2020.11.016

The Lysosome at the Intersection of Cellular Growth and Destruction

Developmental Cell(2020)

co-cited

10.1016/j.devcel.2020.06.010

Iron chelation inhibits mTORC1 signaling involving activation of AMPK and REDD1/Bnip3 pathways

Oncogene(2020)

co-cited

10.1038/s41388-020-1366-5

AMPK regulation of Raptor and TSC2 mediate metformin effects on transcriptional control of anabolism and inflammation

Genes & Development(2020)

co-cited

10.1101/gad.339895.120

Tonic prime-boost of STING signalling mediates Niemann–Pick disease type C

Nature(2021)

co-cited

10.1038/s41586-021-03762-2

GABARAP sequesters the FLCN-FNIP tumor suppressor complex to couple autophagy with lysosomal biogenesis

N/A

3.4DataRank · unranked

Science Advances(2021)

co-cited

10.1126/sciadv.abj2485

Post-Golgi carriers, not lysosomes, confer lysosomal properties to pre-degradative organelles in normal and dystrophic axons

N/A

0.683DataRank · unranked

Cell Reports(2021)

co-cited

10.1016/j.celrep.2021.109034