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A molecular sensor determines the ubiquitin substrate specificity of SARS-CoV-2 papain-like protease

Cell Reports(2021)10.1016/j.celrep.2021.109754Source: DataRank Database

A molecular sensor determines the ubiquitin substrate specificity of SARS-CoV-2 papain-like protease is a research paper published in Cell Reports (2021). On theSindex it has a DataRank of 0. It has been cited 53 times.

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Open Access53 citations

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cellosaurus refseq pdb

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (26 grants)OA: goldTopics (42)IDs (PubMed, PMC)Annotations (3)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (7)

Zongyang Lv ORCID,Wioletta Rut ORCID,Miklós Békés ORCID,Marcin Drąg ORCID,Shaun K. Olsen ORCID

Live enrichment

PubMed:34547223 PMC:PMC8423903

NCI NIH HHS

Grant: P30 CA054174

American Cancer Society

Grant: PF-18-235-01-RMC

Cancer Prevention and Research Institute of Texas

Grant: R01 GM128731

Cancer Prevention and Research Institute of Texas

Grant: RR200030

NIGMS NIH HHS

Grant: P30 GM124165

Cancer Prevention and Research Institute of Texas

Grant: R35 GM139610

NIGMS NIH HHS

Grant: R01 GM115568

Narodowe Centrum Nauki

Grant: 2015/17/N/ST5/03072

NIH HHS

Grant: S10 OD021527

Narodowe Centrum Nauki

Grant: UMO-2020/01/0/NZ1/00063

NIEHS NIH HHS

Grant: R01 ES025166

Narodowe Centrum Nauki

Grant: TEAM/2017-4/32

Argonne National Laboratory

Grant: DE-AC02-06CH11357

National Institutes of Health

Grant: 3P30GM124165-03S1

NE-CAT: A Resource for Advanced Macromolecular Crystallography

National Institutes of Health

Grant: 5R01GM115568-09

Structural Biology of the Ubiquitin Conjugation System

National Institutes of Health

Grant: 7R01GM128731-03

Structure and Function of the Essential Cell Cycle Regulator Cdc34

National Institutes of Health

Grant: 5R35GM139610-03

Understanding the mechanistic role of genome stability pathways in regulating cell homeostasis

National Institutes of Health

Grant: 5R01ES025166-04

Mechanisms of reversible DUB oxidation in genome stability pathways

National Institutes of Health

Grant: 1S10OD021527-01

Pixel Array Detector for Macromolecular Crystallography

National Institutes of Health

Grant: 5P30CA054174-16

SAN ANTONIO CANCER INSTITUTE

Fundacja na rzecz Nauki Polskiej

European Regional Development Fund

National Institute of General Medical Sciences

Office of Science

U.S. Department of Energy

European Commission

goldLicense: CC BY NC ND

publisherhttps://doi.org/10.1016/j.celrep.2021.109754

repositoryhttps://doaj.org/article/06ae877aa85148879905aa3b2b01ed9c

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8423903

Europe_PMChttps://europepmc.org/articles/PMC8423903

Europe_PMChttps://europepmc.org/articles/PMC8423903?pdf=render

Fields of Study

0301 basic medicine03 medical and health sciences

MeSH Terms

HumansPeptide HydrolasesPapainUbiquitinsUbiquitinViral ProteinsBinding SitesAmino Acid SequenceProtein BindingSubstrate SpecificityHEK293 CellsCOVID-19SARS-CoV-2Coronavirus Papain-Like Proteases

Keywords

Cysteine proteaseUbiquitinCoronavirusDubIsg15DeubiquitinasePapain-like ProteasePlproCovid-19Sars-cov-2Sars-cov-1K48-Linked UbBinding SitesQH301-705.5Coronavirus Papain-Like ProteasesSubstrate SpecificityViral ProteinsHEK293 CellsReportPapainHumansAmino Acid SequenceBiology (General)UbiquitinsPeptide HydrolasesProtein Binding

Sustainable Development Goals

SDG 3: 3. Good health