scREAD: A Single-Cell RNA-Seq Database for Alzheimer's Disease is a dataset published in iScience (2020). On theSindex it has a DataRank of 3.3, placing it in the top 6.7% of the data-sharing corpus. It has been cited 154 times, with 100 citing works in its 1-hop citation network. Its calibrated FAIR score is 50/100.
Ranks in the top 7% for downstream scientific impact
Linked data & code
DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?
FAIR checklist signals are shown for context only and do not affect DataRank scoring.
Full FAIR picture · advisory
The headline score is computed from the scored criteria — the fact-shaped checks (a repository, an accession, a licence) that two independent models agree on. The advisory criteria below are real FAIR guidance but rest on judgment calls that models read differently, so they inform without moving the number.
“scREAD is a one-stop and user-friendly interface and freely available at https://bmbls.bmi.osumc.edu/scread/”
The paper gives a web URL, not a persistent identifier scheme (DOI, Handle, ARK, or repository accession). [majority verdict 'partial' (4/5 passes agreed)]
RDA-F1-01D — FAIR Data Maturity Model: 'Data is identified by a persistent identifier' (priorit · RDA-F1-02D — FAIR Data Maturity Model: 'Data is identified by a globally unique identifier' · FsF-F1-02D — F-UJI/FAIRsFAIR: 'Data is assigned a persistent identifier'
“scREAD is a one-stop and user-friendly interface and freely available at https://bmbls.bmi.osumc.edu/scread/”
The holder is a university website (OSU BMBL), not a recognised data repository. [majority verdict 'partial' (4/5 passes agreed)]
RDA-F4-01M — FAIR Data Maturity Model: metadata is offered so it can be harvested and indexed ( · NIH DMS Policy Element 4 (NOT-OD-21-014) — name the repository where data will be archived · NSTC Desirable Characteristics of Data Repositories (2022) — 'Long-Term Sustainability', 'Reten
“scREAD is a one-stop and user-friendly interface and freely available at https://bmbls.bmi.osumc.edu/scread/”
The dataset identifier (URL) appears only in the body text, not as a reference-list entry. [majority verdict 'partial' (4/5 passes agreed)]
FORCE11 Joint Declaration of Data Citation Principles (2014) — data should be cited as a first- · RDA-F3-01M — metadata clearly and explicitly includes the identifier of the data it describes · FsF-F3-01M — F-UJI: 'Metadata includes the identifier of the data it describes'
Advisory · not in the published score
“All data sets used in this work are available from publicly available sources as cited in the manuscript. scREAD is a one-stop and user-friendly interface and freely available at https://bmbls.bmi.osumc.edu/scread/ . The backend workflow can be downloaded from https://github.com/OSU-BMBL/scread/tree/master/script to enable more discovery-driven analyses.”
The statement points to a URL (the scREAD website) and GitHub, not to a repository record with an accession. [majority verdict 'partial' (4/5 passes agreed)]
Colavizza, Hrynaszkiewicz, Staden, Whitaker & McGillivray (2020), 'The citation advantage of li · Springer Nature research data policy — Data Availability Statements: standard statement templat · RDA-F3-01M — metadata clearly and explicitly includes the identifier of the data it describes
“scREAD provides comprehensive analysis results for 73 data sets from 10 brain regions, including control atlas construction, cell-type prediction, identification of differentially expressed genes, and identification of cell-type-specific regulons.”
The dataset content is described in running prose, not in an itemised inventory section or table.
RDA-F2-01M — 'Rich metadata is provided to allow discovery' (priority Essential) · FsF-F2-01M — F-UJI: 'Metadata includes descriptive core elements to support data findability' · FsF-R1-01MD — F-UJI: 'Metadata specifies the content of the data'
“scREAD is a one-stop and user-friendly interface and freely available at https://bmbls.bmi.osumc.edu/scread/”
The text states the scREAD database is freely available without any precondition. [majority verdict 'yes' (4/5 passes agreed)]
RDA-A1.1-01D — 'Data is accessible through a free access protocol' · FsF-A1-01M — F-UJI: 'Metadata contains access level and access conditions of the data' · NSTC Desirable Characteristics of Data Repositories (2022) — 'Free and Easy Access'
Advisory · not in the published score
“scREAD is a one-stop and user-friendly interface and freely available at https://bmbls.bmi.osumc.edu/scread/”
The paper uses the natural-language label 'freely available' to describe the access level of the scREAD database. [majority verdict 'yes' (4/5 passes agreed)]
FsF-A1-01M — F-UJI: 'Metadata contains access level and access conditions of the data' · RDA-A1-01M — metadata contains information to enable the user to get access to the data · COAR Controlled Vocabularies — Access Rights v1.0 (open / embargoed / restricted / metadata-onl
The scREAD database is aggregated from public data and is freely available; no gatekeeper is named.
NIH Genomic Data Sharing Policy (NOT-OD-14-124) — controlled-access via a Data Access Committee · RDA-A1.2-01D — 'Data is accessible through an access protocol that supports authentication and · NIH DMS Policy Element 5 (NOT-OD-21-014) — Access, Distribution, or Reuse Considerations (conse
No sentence states how long the data will persist or when they become available; only a vague future enrichment is mentioned. [majority verdict 'no' (3/5 passes agreed)]
NIH DMS Plan Element 4 (NOT-OD-21-014) — Data Preservation, Access, and Associated Timelines · NSTC Desirable Characteristics (2022), Organizational Infrastructure: 'Retention Policy' · RDA-A2-01M — 'Metadata is guaranteed to remain available after data is no longer available'
No file format is named for the released data (the scREAD database is a web interface).
FsF-R1.3-02D — F-UJI: 'Data is available in a file format recommended by the target research co · RDA-R1.3-02D — data is expressed in a machine-understandable community standard · RDA-I1-01D — data uses a knowledge representation expressed in a standardised format
Advisory · not in the published score
No community standard for data or metadata (e.g., MIAME, BIDS, an ontology) is named as applied to the scREAD data. [majority verdict 'no' (2/5 passes agreed)]
RDA-R1.3-01M — 'Metadata complies with a community standard' (priority Essential) · RDA-R1.3-01D — 'Data complies with a community standard' · RDA-I2-01M — '(Meta)data use vocabularies that follow FAIR principles'
No identifier for a resource other than the paper's own dataset appears in the text (GEO/Synapse are mentioned only as sources, without specific accessions).
RDA-I3-01M — '(meta)data include references to other (meta)data' · RDA-I3-03M — 'metadata includes qualified references to other metadata' · FsF-I3-01M — F-UJI: 'Metadata includes links between the data and its related entities'
No licence is stated for the scREAD database; the CC BY-NC-ND licence applies only to the article.
RDA-R1.1-01M — 'Metadata includes information about the licence under which the data can be reu · RDA-R1.1-02M — 'Metadata refers to a standard reuse licence' · RDA-R1.1-03M — 'Metadata refers to a machine-understandable reuse licence'
“These data sets have been published and freely accessible in the public domain as of September 22nd, 2020.”— not found in the paper; verdict downgraded
A date (September 22nd, 2020) is given, but no version token. [downgraded to 'no' — no verifiable quote from the paper] [majority verdict 'no' (3/5 passes agreed)]
DataCite Metadata Schema 4.6 — the 'Version' property · RDA-R1.2-01M — provenance information (which version was used is provenance) · NSTC Desirable Characteristics of Data Repositories (2022) — 'Provenance', 'Retention Policy'
“The backend workflow can be downloaded from https://github.com/OSU-BMBL/scread/tree/master/script to enable more discovery-driven analyses.”
A machine-resolvable code repository URL is provided. [majority verdict 'yes' (4/5 passes agreed)]
NIH DMS Policy Element 2 (NOT-OD-21-014) — 'Related Tools, Software and/or Code' · FAIR4RS Principles v1.0 (Chue Hong et al., 2022; RDA/FORCE11/ReSA) — FAIR Principles for Resear · FORCE11 Software Citation Principles (Smith, Katz & Niemeyer, 2016, PeerJ CS 2:e86)
“This work was supported by the National Institutes of Health [R01 GM131399-01, Q.M.; K01 AG056673, H.F.], the Department of Defense [W81XWH1910309, H.F.]”
Award/grant numbers are given (R01 GM131399-01, K01 AG056673, W81XWH1910309). [majority verdict 'yes' (4/5 passes agreed)]
DataCite Metadata Schema 4.6 — 'FundingReference' property (funderName, funderIdentifier, award · Crossref Funder Registry — canonical funder identifiers for funding metadata · RDA-F2-01M — rich metadata provided to allow discovery (funding is part of the descriptive reco
Advisory · not in the published score
“Cell types of these 23 control atlases were assigned using Seurat and Semi-supervised Category Identification and Assignment (SCINA)”— not found in the paper; verdict downgraded
The paper names specific software tools (Seurat, SCINA) used to produce the data. [downgraded to 'partial' — no verifiable quote from the paper]
RDA-R1.2-01M — 'Metadata includes provenance information according to community- specific standa · FsF-R1.2-01M — F-UJI: 'Metadata includes provenance information about data creation or generati · W3C PROV-O (W3C Recommendation, 2013) — the entity/activity/agent model of provenance
No documentation object (README, codebook) is mentioned as accompanying the data, and no variable-definition table is present in the article. [majority verdict 'no' (3/5 passes agreed)]
RDA-R1-01M — '(Meta)data are richly described with a plurality of accurate and relevant attribu · FsF-R1-01MD — F-UJI: 'Metadata specifies the content of the data' · NIH DMS Policy Element 3 (NOT-OD-21-014) — Standards (documentation and metadata to accompany t
Calibrated FAIR score — a parallel quality metric, independent of the DataRank citation score. See the full evaluation →
Base Score Contribution
0.757
From this paper's citation signal
Citation Network Contribution
2.6
From 100 citing papers with measurable signal
Ranked by each citer's contribution to N(p) — log1p(Cq) divided by its reference count — out of 100 citers.
National Institutes of Health
Grant: 1K01AG056673-01
Investigating the vulnerability of WFS1-expressing excitatory neurons to tau pathology in early Alzheimer's disease.
National Institutes of Health
Grant: 7R01GM131399-02
Construction of cell specific gene co-regulations signatures based on single cell transcriptomics analysis
FWCI
7.86
Citation Percentile
1.0%
Citation Trend
Fields of Study
Keywords
Sustainable Development Goals
Additional file 10 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions
Additional file 10 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions
Additional file 11 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions
Additional file 11 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions
Additional file 1 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions
Additional file 1 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions
Additional file 2 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions
Additional file 2 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions
Additional file 3 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions
Additional file 3 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions
Additional file 4 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions
Additional file 4 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions
Additional file 5 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions
Additional file 5 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions
Additional file 6 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions
Additional file 6 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions
Additional file 7 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions
Additional file 7 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions
Additional file 8 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions
Additional file 8 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions