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Quantification of Cas9 binding and cleavage across diverse guide sequences maps landscapes of target engagement

Science Advances(2021)10.1126/sciadv.abe5496Source: DataRank Database

Quantification of Cas9 binding and cleavage across diverse guide sequences maps landscapes of target engagement is a research paper published in Science Advances (2021). On theSindex it has a DataRank of 0. It has been cited 65 times.

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Open Access65 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (23 grants)Impact (FWCI 3.48)OA: goldTopics (16)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Winston R. Becker ORCID,Hua Bai ORCID,Janice S. Chen ORCID,Jennifer A. Doudna ORCID,William J. Greenleaf ORCID

Live enrichment

PubMed:33608277 PMC:PMC7895440 OpenAlex:https://openalex.org/W3131855456

National Institutes of Health

Grant: R01GM111990

National Institutes of Health

Grant: P50HG007735

National Institutes of Health

Grant: R01HG009909

National Institutes of Health

Grant: P01GM066275

National Institutes of Health

Grant: UM1HG009436

National Institutes of Health

Grant: R01GM121487

NIAID NIH HHS

Grant: U19 AI057266

NIGMS NIH HHS

Grant: T32 GM007365

NHGRI NIH HHS

Grant: T32 HG000044

NHGRI NIH HHS

Grant: RM1 HG007735

National Institutes of Health

Grant: 5P50HG007735-02

Project 4

National Institutes of Health

Grant: 5R01GM111990-02

Quantitative high-throughput nucleic acid assays on a sequencing chip

National Institutes of Health

Grant: 3P01GM066275-09S1

Fundamental Studies of RNA Folding

National Institutes of Health

Grant: 5R01GM121487-02

High-resolution modeling of protein-RNA interfaces

National Institutes of Health

Grant: 5R01HG009909-02

Genome wide identification and functional analysis of chromatin regulatory RNAs

National Institutes of Health

Grant: 1F32GM013039-01

MOLECULAR ANALYSIS OF THE YEAST HEAT SHOCK TRANSCRIPTION

National Institutes of Health

Grant: 5UM1HG009436-02

High-throughput systematic characterization of regulatory element function

National Institutes of Health

Grant: 3U19AI057266-05S1

IMMUNOLOGICAL MEMORY TO VACCINATION

National Institutes of Health

Grant: 5T32GM007365-23

MEDICAL SCIENTIST TRAINING PROGRAM

National Science Foundation

Chan Zuckerberg Initiative

Helen Hay Whitney Foundation

Howard Hughes Medical Institute

FWCI

3.48

Citation Percentile

0.9%

Citation Trend

2021

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://www.science.org/doi/pdf/10.1126/sciadv.abe5496?download=true

publisherhttps://www.science.org/doi/pdf/10.1126/sciadv.abe5496?download=true

publisherhttps://syndication.highwire.org/content/doi/10.1126/sciadv.abe5496

publisherhttps://www.science.org/doi/pdf/10.1126/sciadv.abe5496

journalhttps://doi.org/10.1126/sciadv.abe5496

Fields of Study

CRISPR and Genetic EngineeringRNA and protein synthesis mechanismsGenetics, Aging, and Longevity in Model Organisms0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

Computational biologyCleavage (geology)Computer scienceBiology570GeneticsGeneric health relevance530Research ArticlesBiotechnology

Sustainable Development Goals

SDG 0: Life in Land