Jennifer A. Doudna

Also affiliated with Gladstone Institutes, Howard Hughes Medical Institute, Lawrence Berkeley National Laboratory, Innovative Genomics Institute, University of California, Berkeley

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

5.6Author DataRank

Indexed papers

5in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 5 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Clades of huge phages from across Earth’s ecosystems

Nature(2020)10.1038/s41586-020-2007-4

Top 4%

5.6DataRank

Top 4%551 citations

Rohan Sachdeva, Lin-Xing Chen, Fred R. Ward, Patrick Munk, Audra E. Devoto +40 more

Papers

Driven by 130 papers — median percentile 96. Top paper: “Amplification-free detection of SARS-CoV-2 with CRISPR-Cas13a and mobile phone microscopy”.

Amplification-free detection of SARS-CoV-2 with CRISPR-Cas13a and mobile phone microscopy

Cell(2020)10.1016/j.cell.2020.12.001

N/A

13.6DataRank · unranked

1034 citations

Sungmin Son, María Díaz de León Derby, Gavin J. Knott, Carley N Gray, Michael V. D’Ambrosio +27 more

The promise and challenge of therapeutic genome editing

Nature(2020)10.1038/s41586-020-1978-5

N/A

11.1DataRank · unranked

1138 citations

Jennifer A. Doudna

Molecular Mechanisms of RNA Interference

Annual Review of Biophysics(2013)10.1146/annurev-biophys-083012-130404

N/A

10.1DataRank · unranked

1080 citations

Jennifer A. Doudna, Ross C. Wilson

Neutralizing immunity in vaccine breakthrough infections from the SARS-CoV-2 Omicron and Delta variants

Cell(2022)10.1016/j.cell.2022.03.019

N/A

9.1DataRank · unranked

176 citations

Abdullah M. Syed, Mary Kate Morris, Noah Brazer, Prachi Saldhi, Miguel Garcia-Knight +19 more

Accelerated RNA detection using tandem CRISPR nucleases

Nature Chemical Biology(2021)10.1038/s41589-021-00842-2

N/A

8.8DataRank · unranked

269 citations

Gavin J. Knott, Dylan C. J. Smock, John J. Desmarais, Sungmin Son, Abdul Bhuiya +43 more

Cap-Independent Translation Is Required for Starvation-Induced Differentiation in Yeast

Science(2007)10.1126/science.1144467

N/A

8.7DataRank · unranked

231 citations

Kaihong Zhou, Tamira K. Butler, Jennifer A. Doudna, Wendy V. Gilbert

eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation

Nature(2016)10.1038/nature18954

N/A

8.4DataRank · unranked

376 citations

Philip J. Kranzusch, Jennifer A. Doudna, Jamie H. D. Cate, Amy S. Y. Lee

Clades of huge phages from across Earth’s ecosystems

Nature(2020)10.1038/s41586-020-2007-4

Top 4%

5.6DataRank

Top 4%551 citations

Rohan Sachdeva, Lin-Xing Chen, Fred R. Ward, Patrick Munk, Audra E. Devoto +40 more

Functional reconstitution of human eukaryotic translation initiation factor 3 (eIF3)

Proceedings of the National Academy of Sciences(2011)10.1073/pnas.1116821108

N/A

4.5DataRank · unranked

110 citations

Aleksandar Todorovic, Jordi Querol-Audí, Yun Bai, Nancy Villa, Monica Snyder +9 more

Mitigation of chromosome loss in clinical CRISPR-Cas9-engineered T cells

Cell(2023)10.1016/j.cell.2023.08.041

N/A

3.4DataRank · unranked

190 citations

Nadav Brandes, Raymund Bueno, Marena Trinidad, Thomas Mazumder, Bingfei Yu +18 more

The HCV IRES pseudoknot positions the initiation codon on the 40S ribosomal subunit

RNA(2010)10.1261/rna.2197210

N/A

3.2DataRank · unranked

77 citations

Shruti Waghray, Jennifer A. Doudna, Katherine E. Berry

Two RNA-binding motifs in eIF3 direct HCV IRES-dependent translation

Nucleic Acids Research(2013)10.1093/nar/gkt510

N/A

3.0DataRank · unranked

82 citations

Jordi Querol-Audí, Stefanie A. Mortimer, Ernesto Arias-Palomo, Jennifer A. Doudna, Eva Nogales +2 more

SARS-CoV-2 variants evolve convergent strategies to remodel the host response

Cell(2023)10.1016/j.cell.2023.08.026

N/A

2.1DataRank · unranked

113 citations

Ann-Kathrin Reuschl, Benjamin J. Polacco, Lucy G. Thorne, Manisha R. Ummadi, Chengjin Ye +88 more

Birth of protein folds and functions in the virome

Nature(2024)10.1038/s41586-024-07809-y

N/A

1.9DataRank · unranked

103 citations

Erin Doherty, Nathan Price, Daniel Bellieny‐Rabelo, Yong K. Zhu, Jennifer A. Doudna +1 more

Precise transcript targeting by CRISPR-Csm complexes

Nature Biotechnology(2023)10.1038/s41587-022-01649-9

N/A

1.9DataRank · unranked

81 citations

Marena Trinidad, Jennifer A. Doudna, David Colognori

Optimizing COVID-19 control with asymptomatic surveillance testing in a university environment

Epidemics(2021)10.1016/j.epidem.2021.100527

N/A

1.5DataRank · unranked

31 citations

Graham R. Northrup, Alexander J. Ehrenberg, Jennifer A. Doudna, Mike Boots, Cara E. Brook

A functional map of HIV-host interactions in primary human T cells

Nature Communications(2022)10.1038/s41467-022-29346-w

N/A

1.2DataRank · unranked

52 citations

Judd F. Hultquist, Michael McGregor, Mehdi Bouhaddou, Ryan T. Leenay, Lacy M. Simons +17 more

CRISPR–Cas9 Structures and Mechanisms

Annual Review of Biophysics(2017)10.1146/annurev-biophys-062215-010822

N/A

1.1DataRank · unranked

2092 citations

Jennifer A. Doudna, Fuguo Jiang

Infant microbiome cultivation and metagenomic analysis reveal Bifidobacterium 2’-fucosyllactose utilization can be facilitated by coexisting species

Nature Communications(2023)10.1038/s41467-023-43279-y

N/A

1.0DataRank · unranked

32 citations

Benjamin E. Rubin, Marie C. Schoelmerich, Kaden S. DiMarco, Adair L. Borges, Rachel Rovinsky +4 more

CRISPR-CasΦ from huge phages is a hypercompact genome editor

Science(2020)10.1126/science.abb1400

N/A

0.951DataRank · unranked

565 citations

Basem Al-Shayeb, Ezra Bisom-Rapp, Connor A. Tsuchida, Zheng Li, Brady F. Cress +5 more

In vivo human T cell engineering with enveloped delivery vehicles

Nature Biotechnology(2024)10.1038/s41587-023-02085-z

N/A

0.828DataRank · unranked

249 citations

Evelyn Chen, Barbara S. Perez, Cindy R. Sandoval Espinoza, Min Hyung Kang, Marena Trinidad +3 more

Limited cross-variant immunity from SARS-CoV-2 Omicron without vaccination

Nature(2022)10.1038/s41586-022-04865-0

N/A

0.806DataRank · unranked

214 citations

Irene P. Chen, Tongcui Ma, Abdullah M. Syed, Noah Brazer, Prachi Saldhi +38 more

Targeted delivery of CRISPR-Cas9 and transgenes enables complex immune cell engineering

Cell Reports(2021)10.1016/j.celrep.2021.109207

N/A

0.803DataRank · unranked

211 citations

Connor A. Tsuchida, David N. Nguyen, Brian R. Shy, E. Riley McGarrigle, Cindy R. Sandoval Espinoza +5 more

DNA capture by a CRISPR-Cas9–guided adenine base editor

Science(2020)10.1126/science.abb1390

N/A

0.803DataRank · unranked

210 citations

Gavin J. Knott, Cody M. Palumbo, Enrique Lin-Shiao, Michelle F. Richter, Kevin T. Zhao +4 more

Omicron mutations enhance infectivity and reduce antibody neutralization of SARS-CoV-2 virus-like particles

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2200592119

N/A

0.802DataRank · unranked

209 citations

Alison Ciling, Taha Y. Taha, Irene P. Chen, Mir M. Khalid, Bharath Sreekumar +16 more

A phage nucleus-associated RNA-binding protein is required for jumbo phage infection

Nucleic Acids Research(2024)10.1093/nar/gkae216

N/A

0.792DataRank · unranked

23 citations

Emily G. Armbruster, Jina Lee, Sitao Zhang, Brian A. Yee, Kseniya Malukhina +16 more

Mitigation of chromosome loss in clinical CRISPR-Cas9-engineered T cells

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.22.533709

N/A

0.762DataRank · unranked

16 citations

Nadav Brandes, Raymund Bueno, Marena Trinidad, Thomas Mazumder, Bingfei Yu +17 more

Rapid detection of SARS-CoV-2 RNA in saliva via Cas13

Nature Biomedical Engineering(2022)10.1038/s41551-022-00917-y

N/A

0.747DataRank · unranked

144 citations

Shreeya Agrawal, Alison Fanton, Aditya R. Jangid, Bérénice Charrez, Arturo M. Escajeda +44 more

The NIH Somatic Cell Genome Editing program

Nature(2021)10.1038/s41586-021-03191-1

N/A

0.736DataRank · unranked

134 citations

Erik J. Sontheimer, Philip J. Brooks, Melinda R. Dwinell, Charles A. Gersbach, David R. Liu +70 more

Machine learning predicts new anti-CRISPR proteins

Nucleic Acids Research(2020)10.1093/nar/gkaa219

N/A

0.717DataRank · unranked

118 citations

Amina Asif, Kyle E. Watters, Anthony T. Iavarone, Gavin J. Knott, Jennifer A. Doudna +2 more

CRISPR–Cas9-mediated nuclear transport and genomic integration of nanostructured genes in human primary cells

Nucleic Acids Research(2022)10.1093/nar/gkac049

N/A

0.661DataRank · unranked

81 citations

Wolfgang Pfeifer, Brian R. Shy, Mohammad Saffari Doost, Evelyn Chen, Vivasvan S. Vykunta +11 more

SARS-CoV-2 evolution balances conflicting roles of N protein phosphorylation

PLoS Pathogens(2024)10.1371/journal.ppat.1012741

N/A

0.655DataRank · unranked

24 citations

Alison Ciling, Irene P. Chen, Christopher R. Carlson, Armin N. Adly, Hannah S. Martin +11 more

An updated evolutionary classification of CRISPR–Cas systems including rare variants

Nature Microbiology(2025)10.1038/s41564-025-02180-8

N/A

0.633DataRank · unranked

67 citations

Sergey Shmakov, Yuri I. Wolf, Pascal Mutz, Han Altae-Tran, Chase L. Beisel +24 more

Direct detection of SARS-CoV-2 using CRISPR-Cas13a and a mobile phone

medRxiv(2020)10.1101/2020.09.28.20201947

N/A

0.614DataRank · unranked

59 citations

Sungmin Son, María Díaz de León Derby, Gavin J. Knott, Carley N Gray, Michael V. D’Ambrosio +23 more

Animal and bacterial viruses share conserved mechanisms of immune evasion

Cell(2024)10.1016/j.cell.2024.07.057

N/A

0.550DataRank · unranked

38 citations

Jason Nomburg, Jennifer A. Doudna, Philip J. Kranzusch, Samuel J. Hobbs

Assembly of SARS-CoV-2 ribonucleosomes by truncated N∗ variant of the nucleocapsid protein

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.105362

N/A

0.550DataRank · unranked

38 citations

Maxine Bi, Christopher R. Carlson, Abdullah M. Syed, Alison Ciling, Jennifer A. Doudna +3 more

Synthesis of Multi-Protein Complexes through Charge-Directed Sequential Activation of Tyrosine Residues

Journal of the American Chemical Society(2021)10.1021/jacs.1c03079

N/A

0.529DataRank · unranked

33 citations

Marco Lobba, Daniel Brauer, Alan M. Marmelstein, Johnathan C. Maza, Jamie M. Gleason +3 more

Global landscape of the host response to SARS-CoV-2 variants reveals viral evolutionary trajectories

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.19.512927

N/A

0.524DataRank · unranked

14 citations

Ann‐Kathrin Reuschl, Benjamin J. Polacco, Lucy G. Thorne, Manisha R. Ummadi, Chengjin Ye +72 more

Targeting the non-coding genome and temozolomide signature enables CRISPR-mediated glioma oncolysis

Cell Reports(2023)10.1016/j.celrep.2023.113339

N/A

0.494DataRank · unranked

26 citations

Alexendar R. Perez, Rachel J. Lew, Xiaoyu Sun, Alisha Baldwin, Yong K. Zhu +5 more

CRISPRi-ART enables functional genomics of diverse bacteriophages using RNA-binding dCas13d

Nature Microbiology(2025)10.1038/s41564-025-01935-7

N/A

0.489DataRank · unranked

25 citations

Muntathar J. Al-Shimary, Jaymin R. Patel, Emily G. Armbruster, David Colognori, Emeric J. Charles +18 more

CRISPR-Cas12a bends DNA to destabilize base pairs during target interrogation

Nucleic Acids Research(2024)10.1093/nar/gkae1192

N/A

0.484DataRank · unranked

11 citations

Joshua C. Cofsky, Owen T. Tuck, Honglue Shi, Jennifer A. Doudna, Katarzyna M. Soczek

Mechanism-guided engineering of a minimal biological particle for genome editing

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2413519121

N/A

0.470DataRank · unranked

22 citations

Julia Peukes, Alisha Baldwin, Zhiwei Wayne Xue, Sidney Hwang, Robert R. Stickels +7 more

Enhanced proofreading governs CRISPR-Cas9 targeting accuracy

10.1101/160036

N/A

0.464DataRank · unranked

21 citations

Yavuz S. Dagdas, Benjamin P. Kleinstiver, Moira M. Welch, Lucas B. Harrington, Samuel H. Sternberg +4 more

Oligomeric State and Drug Binding of the SARS-CoV-2 Envelope Protein Are Sensitive to the Ectodomain

Journal of the American Chemical Society(2024)10.1021/jacs.4c07686

N/A

0.425DataRank · unranked

16 citations

Iva Sučec, João Medeiros‐Silva, Hyunil Jo, Richard T. Beresis, Abdullah M. Syed +3 more

Directed evolution expands CRISPR–Cas12a genome-editing capacity

Nucleic Acids Research(2025)10.1093/nar/gkaf649

N/A

0.425DataRank · unranked

16 citations

Kai Chen, Honglue Shi, Kevin Wasko, Isabel Esain-Garcia, Marena Trinidad +4 more

Sensitive and multiplexed RNA detection with Cas13 droplets and kinetic barcoding

medRxiv(2021)10.1101/2021.08.02.21261509

N/A

0.416DataRank · unranked

15 citations

Amy Lyden, Jeffrey Shu, Stephanie I. Stephens, Parinaz Fozouni, Gavin J. Knott +9 more

Rapid DNA unwinding accelerates genome editing by engineered CRISPR-Cas9

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.14.571777

N/A

0.385DataRank · unranked

12 citations

Kai Chen, Katarzyna M. Soczek, Owen T. Tuck, Erin Doherty, Brittney W. Thornton +4 more

Characterizing and controlling CRISPR repair outcomes in nondividing human cells

Nature Communications(2025)10.1038/s41467-025-66058-3

N/A

0.381DataRank · unranked

11 citations

Samali J. Namaganda, Manasi M. Kumar, Jennifer Hamilton, Rohit Sharma, Karena G. Chow +23 more

Comprehensive deletion landscape of CRISPR-Cas9 identifies minimal RNA-guided DNA-binding modules

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.19.344077

N/A

0.345DataRank · unranked

9 citations

Sean Higgins, Christof Fellmann, Thomas G. Laughlin, Benjamin L. Oakes, R A Lew +6 more

Previous exposure to Spike-providing parental strains confers neutralizing immunity to XBB lineage and other SARS-CoV-2 recombinants in the context of vaccination

Emerging Microbes & Infections(2023)10.1080/22221751.2023.2270071

N/A

0.340DataRank · unranked

5 citations

Taha Y. Taha, Maria McCavitt-Malvido, Inês Silva, Mir M. Khalid, Abdullah M. Syed +28 more

Publisher Correction: Accelerated RNA detection using tandem CRISPR nucleases

Nature Chemical Biology(2021)10.1038/s41589-021-00882-8

N/A

0.330DataRank · unranked

8 citations

Gavin J. Knott, Dylan C. J. Smock, John J. Desmarais, Sungmin Son, Abdul Bhuiya +43 more

Regulation of virion production by the ORF8 signal peptide across SARS-CoV-2 variants

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.05.583578

N/A

0.330DataRank · unranked

8 citations

Irene P. Chen, Frank S Soveg, Taha Y. Taha, Takako Tabata, Rahul Suryawanshi +16 more

A phage nucleus-associated RNA-binding protein is required for jumbo phage infection

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.22.559000

N/A

0.312DataRank · unranked

7 citations

Emily G. Armbruster, Jina Lee, Sitao Zhang, Brian A. Yee, Yajie Gu +14 more

Decorating chromatin for enhanced genome editing using CRISPR-Cas9

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.15.484540

N/A

0.269DataRank · unranked

5 citations

Enrique Lin-Shiao, Marena Trinidad, Mohammad Saffari Doost, David Colognori, Jennifer A. Doudna +1 more

CRISPR-Cas9 mediated nuclear transport and genomic integration of nanostructured genes in human primary cells

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.08.467750

N/A

0.241DataRank · unranked

4 citations

Wolfgang Pfeifer, Brian R. Shy, Mohammad Saffari Doost, Evelyn Chen, Vivasvan S. Vykunta +11 more

Improved Genome Editing by an Engineered CRISPR-Cas12a

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.02.506401

N/A

0.165DataRank · unranked

2 citations

Kai Chen, Honglue Shi, Elizabeth C. Stahl, Benjamin A. Adler, Junjie Liu +4 more

Recurrent acquisition of nuclease-protease pairs in antiviral immunity

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.28.667249

N/A

0.165DataRank · unranked

2 citations

Jason J. Hu, Benjamin A. Adler, Claire E O'Brien, Santiago C. Lopez, K.‐H. HSIEH +5 more

CRISPR-Cas12a bends DNA to destabilize base pairs during target interrogation

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.07.31.606079

N/A

0.104DataRank · unranked

1 citations

Joshua C. Cofsky, Owen T. Tuck, Honglue Shi, Jennifer A. Doudna, Katarzyna M. Soczek

Single-molecule live-cell RNA imaging with CRISPR–Csm

Nature Biotechnology(2025)10.1038/s41587-024-02540-5

N/A

0DataRank · unranked

43 citations

David Colognori, X. Jiang, Ke Xu, Jennifer A. Doudna, Chenglong Xia

Packaged delivery of CRISPR–Cas9 ribonucleoproteins accelerates genome editing

Nucleic Acids Research(2025)10.1093/nar/gkaf105

N/A

0DataRank · unranked

24 citations

Madeline Zoltek, Kevin Wasko, Angel Menendez Vazquez, Jinna Brim, Wayne Ngo +3 more

Rapid two-step target capture ensures efficient CRISPR-Cas9-guided genome editing

Molecular Cell(2025)10.1016/j.molcel.2025.03.024

N/A

0DataRank · unranked

21 citations

Noor Al-Sayyad, Kevin Wasko, Marena Trinidad, Erin Doherty, Kamakshi Vohra +7 more

Sequential membrane- and protein-bound organelles compartmentalize genomes during phage infection

Cell Host & Microbe(2025)10.1016/j.chom.2025.03.005

N/A

0DataRank · unranked

20 citations

Phoolwanti Rani, Jina Lee, N. Klusch, Joshua Hutchings, Lizbeth Y. Hoffman +22 more

A miniature CRISPR–Cas10 enzyme confers immunity by inhibitory signalling

Nature(2025)10.1038/s41586-025-09569-9

N/A

0DataRank · unranked

14 citations

Benjamin A. Adler, Peter H. Yoon, K.‐H. HSIEH, Kenneth J. Loi, Emily G. Armbruster +8 more

Dynamic basis of supercoiling-dependent DNA interrogation by Cas12a via R-loop intermediates

Nature Communications(2025)10.1038/s41467-025-57703-y

N/A

0DataRank · unranked

10 citations

Joshua C. Cofsky, Honglue Shi, Noor Al-Sayyad, Ivan E. Ivanov, Ashwin Balaji +3 more

Temporal photoproximity labeling of ligand-activated EGFR neighborhoods using MultiMap

Nature Chemical Biology(2025)10.1038/s41589-025-02076-y

N/A

0DataRank · unranked

7 citations

Wayne Ngo, Yu‐Ting Chou, Harry X. Wu, Katherine J. Susa, Young-wook Jun +4 more

Divergent viral phosphodiesterases for immune signaling evasion

Cell Host & Microbe(2025)10.1016/j.chom.2025.10.018

N/A

0DataRank · unranked

4 citations

Jason Nomburg, Benjamin A. Adler, Santiago M. C. Lopez, K.‐H. HSIEH, Nathan Price +3 more

Functional protein mining with conformal guarantees

Nature Communications(2025)10.1038/s41467-024-55676-y

N/A

0DataRank · unranked

6 citations

Seyone Chithrananda, Anastasios N. Angelopoulos, Peter H. Yoon, Michael I. Jordan, Jennifer A. Doudna +1 more

Recurrent acquisition of nuclease-protease pairs in antiviral immunity

Science(2025)10.1126/science.aea8769

N/A

0DataRank · unranked

3 citations

Jason J. Hu, Santiago C. Lopez, Benjamin A. Adler, Claire E O'Brien, K.‐H. HSIEH +7 more

Mutational scanning of TnpB reveals latent activity for genome editing

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.02.11.637750

N/A

0DataRank · unranked

9 citations

Rachel F. Weissman, Jorge Rodríguez, Ryan Tran, Bao Chau Duong, Cynthia I. Terrace +12 more

Improving RNA Secondary Structure Prediction Through Expanded Training Data

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.03.652028

N/A

0DataRank · unranked

1 citations

Taehan Kim, Roma Nagle, C. A. Meredith, Dimple Amitha Garuadapuri, Jennifer A. Doudna +2 more

Programmable kinetic barcoding for multiplexed RNA detection with Cas13a

medRxiv(2025)10.1101/2025.07.03.25328829

N/A

0DataRank · unranked

0 citations

Amy Lyden, Carlos Ng Pitti, Andres Dextre, Jeffrey Shu, Stephanie I Stephens +11 more

Divergent viral phosphodiesterases for immune signaling evasion

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.21.671373

N/A

0DataRank · unranked

0 citations

Jason Nomburg, Benjamin A. Adler, Santiago M. C. Lopez, K.‐H. HSIEH, Nathan Price +3 more

Eukaryotic RNA-guided endonucleases evolved from a unique clade of bacterial enzymes

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.09.552727

N/A

0DataRank · unranked

2 citations

Petr Skopintsev, Honglue Shi, Lin-Xing Chen, Benjamin A. Adler, Muntathar Al-Shimary +12 more

Massively parallel kinetic profiling of natural and engineered CRISPR nucleases

Nature Biotechnology(2020)10.1038/s41587-020-0646-5

N/A

0DataRank · unranked

144 citations

John A. Hawkins, Nicole V. Johnson, Cheulhee Jung, Kuang Hu, James R. Rybarski +5 more

Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.1913445117

N/A

0DataRank · unranked

127 citations

Addison V. Wright, Joshua C. Cofsky, Kevin Aris, Jennifer A. Doudna, Zev Bryant +1 more

Chemistry of Class 1 CRISPR-Cas effectors: Binding, editing, and regulation

Journal of Biological Chemistry(2020)10.1074/jbc.rev120.007034

N/A

0DataRank · unranked

122 citations

Jennifer A. Doudna, Tina Y. Liu

Site-Specific Bioconjugation through Enzyme-Catalyzed Tyrosine–Cysteine Bond Formation

ACS Central Science(2020)10.1021/acscentsci.0c00940

N/A

0DataRank · unranked

96 citations

Christof Fellmann, Alan M. Marmelstein, Johnathan C. Maza, Elijah N. Kissman, Stephanie A. Robinson +7 more

A scoutRNA Is Required for Some Type V CRISPR-Cas Systems

Molecular Cell(2020)10.1016/j.molcel.2020.06.022

N/A

0DataRank · unranked

76 citations

Enbo Ma, Janice S. Chen, Isaac P. Witte, Dov Gertz, David Páez-Espino +6 more

Potent CRISPR-Cas9 inhibitors from Staphylococcus genomes

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.1917668117

N/A

0DataRank · unranked

68 citations

Haridha Shivram, Christof Fellmann, Rachel J. Lew, Blake McMahon, Jennifer A. Doudna +1 more

Rapid, point-of-care molecular diagnostics with Cas13

medRxiv(2020)10.1101/2020.12.14.20247874

N/A

0DataRank · unranked

21 citations

Alison Fanton, Sita S. Chandrasekaran, Bérénice Charrez, Arturo M. Escajeda, Sungmin Son +26 more

Cancer-specific loss of TERT activation sensitizes glioblastoma to DNA damage

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.25.061606

N/A

0DataRank · unranked

0 citations

Christof Fellmann, Katarzyna M. Soczek, Shawn M. Ren, Rachel J. Lew, Gavin J. Knott +6 more

Rapid assessment of SARS-CoV-2–evolved variants using virus-like particles

Science(2021)10.1126/science.abl6184

N/A

0DataRank · unranked

356 citations

Taha Y. Taha, Takako Tabata, Irene P. Chen, Alison Ciling, Mir M. Khalid +7 more

Kinetic analysis of Cas12a and Cas13a RNA-Guided nucleases for development of improved CRISPR-Based diagnostics

iScience(2021)10.1016/j.isci.2021.102996

N/A

0DataRank · unranked

120 citations

Nidhi Patel, Philip J. Y. Leung, Zeba Islam, Remy M. Kooistra, Ishira Parikh +6 more

Human Molecular Genetics and Genomics — Important Advances and Exciting Possibilities

New England Journal of Medicine(2021)10.1056/nejmp2030694

N/A

0DataRank · unranked

78 citations

Jennifer A. Doudna, Eric S. Lander, Charles N. Rotimi, Francis S. Collins

Quantification of Cas9 binding and cleavage across diverse guide sequences maps landscapes of target engagement

Science Advances(2021)10.1126/sciadv.abe5496

N/A

0DataRank · unranked

65 citations

Winston R. Becker, Hua Bai, Janice S. Chen, Jennifer A. Doudna, William J. Greenleaf +1 more

Comprehensive deletion landscape of CRISPR-Cas9 identifies minimal RNA-guided DNA-binding modules

Nature Communications(2021)10.1038/s41467-021-25992-8

N/A

0DataRank · unranked

53 citations

Sean Higgins, Christof Fellmann, Thomas G. Laughlin, Benjamin L. Oakes, R A Lew +7 more

Cancer-specific loss of TERT activation sensitizes glioblastoma to DNA damage

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2008772118

N/A

0DataRank · unranked

52 citations

Christof Fellmann, Katarzyna M. Soczek, Shawn M. Ren, Rachel J. Lew, Gavin J. Knott +6 more

Robotic RNA extraction for SARS-CoV-2 surveillance using saliva samples

PLoS ONE(2021)10.1371/journal.pone.0255690

N/A

0DataRank · unranked

19 citations

Elizabeth C. Stahl, Connor A. Tsuchida, Enrique Lin-Shiao, C. Kimberly Tsui, Kathleen Pestal +16 more

LuNER: Multiplexed SARS-CoV-2 detection in clinical swab and wastewater samples

PLoS ONE(2021)10.1371/journal.pone.0258263

N/A

0DataRank · unranked

6 citations

Allan Gopez, Connor A. Tsuchida, Vinson B. Fan, Erica A. Moehle, Lea B. Witkowsky +21 more

Omicron mutations enhance infectivity and reduce antibody neutralization of SARS-CoV-2 virus-like particles

medRxiv(2021)10.1101/2021.12.20.21268048

N/A

0DataRank · unranked

75 citations

Alison Ciling, Mir M. Khalid, Bharath Sreekumar, Peiyi Chen, G. Renuka Kumar +15 more

Engineering improved Cas13 effectors for targeted post-transcriptional regulation of gene expression

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.26.445687

N/A

0DataRank · unranked

37 citations

Shineui Kim, Gavin J. Knott, Dylan C. J. Smock, Jennifer A. Doudna, David F. Savage +1 more

Accelerated RNA detection using tandem CRISPR nucleases

medRxiv(2021)10.1101/2021.03.19.21253328

N/A

0DataRank · unranked

21 citations

Gavin J. Knott, Dylan C. J. Smock, John J. Desmarais, Sungmin Son, Abdul Bhuiya +29 more

Diverse ATPase proteins in mobilomes constitute a large potential sink for prokaryotic host ATP

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.01.438130

N/A

0DataRank · unranked

3 citations

Haridha Shivram, Shufei Lei, Jennifer A. Doudna, Jillian F. Banfield, Hyunjin Shim

A naturally DNase-free CRISPR-Cas12c enzyme silences gene expression

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.06.471469

N/A

0DataRank · unranked

3 citations

Benjamin A. Adler, Jennifer A. Doudna, Carolyn J. Huang

CRISPR-Cas9 bends and twists DNA to read its sequence

Research Square(2021)10.21203/rs.3.rs-882403/v1

N/A

0DataRank · unranked

2 citations

Joshua C. Cofsky, Katarzyna M. Soczek, Gavin J. Knott, Eva Nogales, Jennifer A. Doudna

Diverse ATPase Proteins in Mobilomes Constitute a Large Potential Sink for Prokaryotic Host ATP

Frontiers in Microbiology(2021)10.3389/fmicb.2021.691847

N/A

0DataRank · unranked

0 citations

Haridha Shivram, Shufei Lei, Jennifer A. Doudna, Jillian F. Banfield, Hyunjin Shim

Synthesis of Multi-Protein Complexes through Charge-Directed Sequential Activation of Tyrosine Residues

ChemRxiv(2021)10.26434/chemrxiv.14251649

N/A

0DataRank · unranked

0 citations

Marco Lobba, Daniel Brauer, Alan M. Marmelstein, Johnathan C. Maza, Jamie M. Gleason +3 more

Improved genome editing by an engineered CRISPR-Cas12a

Nucleic Acids Research(2022)10.1093/nar/gkac1192

N/A

0DataRank · unranked

109 citations

Kai Chen, Honglue Shi, Elizabeth C. Stahl, Benjamin A. Adler, Marena Trinidad +5 more

CRISPR–Cas9 bends and twists DNA to read its sequence

Nature Structural & Molecular Biology(2022)10.1038/s41594-022-00756-0

N/A

0DataRank · unranked

84 citations

Katarzyna M. Soczek, Gavin J. Knott, Eva Nogales, Jennifer A. Doudna, Joshua C. Cofsky

A naturally DNase-free CRISPR-Cas12c enzyme silences gene expression

Molecular Cell(2022)10.1016/j.molcel.2022.04.020

N/A

0DataRank · unranked

51 citations

Benjamin A. Adler, Jennifer A. Doudna, Carolyn J. Huang

Decorating chromatin for enhanced genome editing using CRISPR-Cas9

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2204259119

N/A

0DataRank · unranked

50 citations

Enrique Lin-Shiao, Marena Trinidad, Mohammad Saffari Doost, David Colognori, Jennifer A. Doudna +1 more

Conserved features of TERT promoter duplications reveal an activation mechanism that mimics hotspot mutations in cancer

Nature Communications(2022)10.1038/s41467-022-33099-x

N/A

0DataRank · unranked

22 citations

Abigail K. Suwala, Katarzyna M. Soczek, Albert Wang, Min Y. Kim, Chibo Hong +6 more

Crystal structure of an RNA/DNA strand exchange junction

PLoS ONE(2022)10.1371/journal.pone.0263547

N/A

0DataRank · unranked

7 citations

Gavin J. Knott, Christine L. Gee, Jennifer A. Doudna, Joshua C. Cofsky

Limited Cross-Variant Immunity after Infection with the SARS-CoV-2 Omicron Variant Without Vaccination

medRxiv(2022)10.1101/2022.01.13.22269243

N/A

0DataRank · unranked

35 citations

Irene P. Chen, Tongcui Ma, Abdullah M. Syed, Noah Brazer, Prachi Saldhi +33 more

Neutralizing immunity in vaccine breakthrough infections from the SARS-CoV-2 Omicron and Delta variants

medRxiv(2022)10.1101/2022.01.25.22269794

N/A

0DataRank · unranked

23 citations

Abdullah M. Syed, Noah Brazer, Prachi Saldhi, Miguel Garcia-Knight, Bharath Sreekumar +16 more

Programmable enveloped delivery vehicles for human genome engineering in vivo

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.24.505004

N/A

0DataRank · unranked

5 citations

Evelyn Chen, Barbara S. Perez, Cindy R. Sandoval Espinoza, Min Hyung Kang, Marena Trinidad +2 more

Rapid assembly of SARS-CoV-2 genomes reveals attenuation of the Omicron BA.1 variant through NSP6

Nature Communications(2023)10.1038/s41467-023-37787-0

N/A

0DataRank · unranked

71 citations

Irene P. Chen, Jennifer M. Hayashi, Takako Tabata, Keith Walcott, Gabriella R. Kimmerly +14 more

Genome editing in the mouse brain with minimally immunogenic Cas9 RNPs

Molecular Therapy(2023)10.1016/j.ymthe.2023.06.019

N/A

0DataRank · unranked

44 citations

Jennifer K. Sabo, Min Hyung Kang, Ryan Allen, Elizabeth Applegate, Shineui Kim +15 more

CasPEDIA Database: a functional classification system for class 2 CRISPR-Cas enzymes

Nucleic Acids Research(2023)10.1093/nar/gkad890

N/A

0DataRank · unranked

38 citations

Marena Trinidad, Daniel Bellieny‐Rabelo, Elaine Zhang, Hannah Karp, Petr Skopintsev +48 more

Eukaryotic RNA-guided endonucleases evolved from a unique clade of bacterial enzymes

Nucleic Acids Research(2023)10.1093/nar/gkad1053

N/A

0DataRank · unranked

37 citations

Petr Skopintsev, Honglue Shi, Lin-Xing Chen, Benjamin A. Adler, Muntathar Al-Shimary +14 more

A transcriptionally active lipid vesicle encloses the injected Chimalliviridae genome in early infection

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.20.558163

N/A

0DataRank · unranked

24 citations

Phoolwanti Rani, Jina Lee, N. Klusch, Joshua Hutchings, Lloyd A. Hoffman +22 more

Lung and liver editing by lipid nanoparticle delivery of a stable CRISPR-Cas9 RNP

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.15.566339

N/A

0DataRank · unranked

23 citations

Hesong Han, Sheng Zhao, Bryant Xu, Boyan Yin, Marena Trinidad +4 more

CasPEDIA Database: A Functional Classification System for Class 2 CRISPR-Cas Enzymes

(2023)10.32942/x2c31f

N/A

0DataRank · unranked

6 citations

Marena Trinidad, Daniel Bellieny‐Rabelo, Elaine Zhang, Hannah Karp, Petr Skopintsev +47 more

Rapid assembly of SARS-CoV-2 genomes reveals attenuation of the Omicron BA.1 variant through NSP6

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.31.525914

N/A

0DataRank · unranked

5 citations

Irene P. Chen, Jennifer M. Hayashi, Takako Tabata, Keith Walcott, Gabriella R. Kimmerly +14 more

Assembly reactions of SARS-CoV-2 nucleocapsid protein with nucleic acid

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.22.568361

N/A

0DataRank · unranked

5 citations

Abdullah M. Syed, Mir M. Khalid, Ai Nguyen, Alison Ciling, Di Wu +8 more

Engineering self-deliverable ribonucleoproteins for genome editing in the brain

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.15.567251

N/A

0DataRank · unranked

2 citations

Elizabeth C. Stahl, Min Hyung Kang, Bryant Xu, Ryan Allen, Marena Trinidad +2 more

Genomic analysis of cultivated infant microbiomes identifies Bifidobacterium 2’-fucosyllactose utilization can be facilitated by co-existing species

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.10.532136

N/A

0DataRank · unranked

0 citations

Benjamin E. Rubin, Marie C. Schoelmerich, Kaden DiMarco, Adair L. Borges, Rachel Rovinsky +4 more

Lung and liver editing by lipid nanoparticle delivery of a stable CRISPR–Cas9 ribonucleoprotein

Nature Biotechnology(2024)10.1038/s41587-024-02437-3

N/A

0DataRank · unranked

127 citations

Hesong Han, Sheng Zhao, Bryant Xu, Boyan Yin, Atip Lawanprasert +5 more

Targeted nonviral delivery of genome editors in vivo

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2307796121

N/A

0DataRank · unranked

71 citations

Kevin Wasko, Jennifer Hamilton, Jennifer A. Doudna, Connor A. Tsuchida

Rapid DNA unwinding accelerates genome editing by engineered CRISPR-Cas9

Cell(2024)10.1016/j.cell.2024.04.031

N/A

0DataRank · unranked

66 citations

Kai Chen, Katarzyna M. Soczek, Owen T. Tuck, Erin Doherty, Bryant Xu +5 more

Engineering self-deliverable ribonucleoproteins for genome editing in the brain

Nature Communications(2024)10.1038/s41467-024-45998-2

N/A

0DataRank · unranked

45 citations

Elizabeth C. Stahl, Min Hyung Kang, Bryant Xu, Ryan Allen, Marena Trinidad +2 more

Assembly of SARS-CoV-2 nucleocapsid protein with nucleic acid

Nucleic Acids Research(2024)10.1093/nar/gkae256

N/A

0DataRank · unranked

44 citations

Abdullah M. Syed, Mir M. Khalid, Ai Nguyen, Alison Ciling, Di Wu +8 more

Genome integrity sensing by the broad-spectrum Hachiman antiphage defense complex

Cell(2024)10.1016/j.cell.2024.09.020

N/A

0DataRank · unranked

39 citations

Benjamin A. Adler, Emily G. Armbruster, Arushi Lahiri, Jason J. Hu, Julia Zhou +3 more

An essential and highly selective protein import pathway encoded by nucleus-forming phage

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2321190121

N/A

0DataRank · unranked

22 citations

Eray Enüstün, Emily G. Armbruster, Erica A. Birkholz, Amy Prichard, Taylor Forman +15 more

RNA language models predict mutations that improve RNA function

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.05.588317

N/A

0DataRank · unranked

11 citations

Marena Trinidad, Conner J. Langeberg, Hunter Nisonoff, Seyone Chithrananda, Petr Skopintsev +11 more

Single-molecule live-cell RNA imaging with CRISPR-Csm

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.07.14.603457

N/A

0DataRank · unranked

5 citations

David Colognori, X. Jiang, Ke Xu, Jennifer A. Doudna, Chenglong Xia

An essential and highly selective protein import pathway encoded by nucleus-forming phage

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.21.585822

N/A

0DataRank · unranked

2 citations

Eray Enüstün, Emily G. Armbruster, Erica A. Birkholz, Amy Prichard, Taylor Forman +15 more

Packaged delivery of CRISPR-Cas9 ribonucleoproteins accelerates genome editing

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.10.18.619117

N/A

0DataRank · unranked

2 citations

Madeline Zoltek, Kevin Wasko, Angel Menendez Vazquez, Jinna Brim, Wayne Ngo +3 more

Spatiotemporal photocatalytic proximity labeling proteomics reveals ligand-activated extracellular and intracellular EGFR neighborhoods

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.12.21.629933

N/A

0DataRank · unranked

1 citations

Wayne Ngo, Yu‐Ting Chou, Harry X. Wu, Katherine J. Susa, Young-wook Jun +4 more

Author Correction: Engineering self-deliverable ribonucleoproteins for genome editing in the brain

Nature Communications(2024)10.1038/s41467-024-48087-6

N/A

0DataRank · unranked

0 citations

Elizabeth C. Stahl, Min Hyung Kang, Bryant Xu, Ryan Allen, Marena Trinidad +2 more

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