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SARS‐CoV‐2 sensing by RIG‐I and MDA5 links epithelial infection to macrophage inflammation

The EMBO Journal(2021)10.15252/embj.2021107826Source: DataRank Database

SARS‐CoV‐2 sensing by RIG‐I and MDA5 links epithelial infection to macrophage inflammation is a research paper published in The EMBO Journal (2021). On theSindex it has a DataRank of 0. It has been cited 228 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access228 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (8 grants)Impact (FWCI 14.10)OA: hybridTopics (83)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

Ann‐Kathrin Reuschl ORCID,Lorena Zuliani‐Alvarez ORCID,Matthew V. X. Whelan ORCID,Jane Turner ORCID,Mahdad Noursadeghi ORCID

Live enrichment

PubMed:34101213 PMC:PMC8209947 OpenAlex:https://openalex.org/W3167578500

Wellcome

Grant: 108183

Characterisation of innate immune DNA sensing and viral evasion strategies.

Wellcome

Grant: 220863

Studying lentiviruses to understand mechanisms, regulation and consequences of nucleic acid sensing

Wellcome

Grant: 108079

Virus-Host interactions regulating HIV-1 replication in T cells.

Wellcome

Grant: 207511

Human Immune Response Variation in Tuberulosis

Medical Research Council

Grant: MR/S023380/1

Wellcome Trust

Grant: 108079/Z/15/Z

Medical Research Council

Grant: G0801172

Medical Research Council

Grant: MR/W005611/1

FWCI

14.10

Citation Percentile

1.0%

Citation Trend

2021

2022

2023

2024

2025

2026

hybridLicense: cc-by

journalhttps://doi.org/10.15252/embj.2021107826

publisherhttps://doi.org/10.15252/embj.2021107826

publisherhttps://link.springer.com/content/pdf/10.15252/embj.2021107826.pdf

publisherhttps://onlinelibrary.wiley.com/doi/full-xml/10.15252/embj.2021107826

publisherhttps://link.springer.com/article/10.15252/embj.2021107826/fulltext.html

Fields of Study

interferon and immune responsesCOVID-19 Clinical Research StudiesInflammasome and immune disorders0301 basic medicine03 medical and health sciencesCOVID-19Cell LineCytokinesDEAD Box Protein 58Epithelial CellsHost-Pathogen InteractionsHumansImmunity, InnateInflammationInterferon-Induced Helicase, IFIH1Janus KinasesLungMacrophage ActivationMacrophagesNF-kappa BRNA, ViralReceptors, ImmunologicRespiratory MucosaSARS-CoV-2STAT Transcription FactorsVirus Replication

MeSH Terms

DEAD Box Protein 58Interferon-Induced Helicase, IFIH1COVID-19SARS-CoV-2Cell LineEpithelial CellsHumansImmunity, InnateInflammationLungMacrophage ActivationMacrophagesReceptors, ImmunologicRNA, ViralVirus ReplicationCytokinesNF-kappa BRespiratory MucosaSTAT Transcription FactorsJanus KinasesHost-Pathogen Interactions

Keywords

InflammationBiologyMDA5Innate immune systemRIG-IImmune systemImmunologyMacrophageCytokineLungRNACell biologyRNA interferenceGeneMedicineEpithelialRna SensingSars-cov-2Interferon-Induced Helicase, IFIH1Respiratory MucosaCell LineHumansReceptors, ImmunologicJanus KinasesMacrophagesNF-kappa BCOVID-19Epithelial CellsArticlesMacrophage ActivationImmunity, InnateSTAT Transcription FactorsHost-Pathogen InteractionsCytokinesDEAD Box Protein 58RNA, Viral

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Quality Education