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Evolutionary divergence in the conformational landscapes of tyrosine vs serine/threonine kinases

eLife(2022)10.7554/elife.83368Source: DataRank Database

Evolutionary divergence in the conformational landscapes of tyrosine vs serine/threonine kinases is a research paper published in eLife (2022). On theSindex it has a DataRank of 0. It has been cited 35 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access35 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)Impact (FWCI 2.04)OA: goldTopics (50)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (4)

Abhishek Thakur ORCID,Allan Haldane ORCID,Ronald M. Levy ORCID,Joan Gizzio

Live enrichment

PubMed:36562610 OpenAlex:https://openalex.org/W4312115132

National Institutes of Health

Grant: R35-GM132090

National Institutes of Health

Grant: OD020095

National Institutes of Health

Grant: 5R35GM132090-05

Mapping Fitness and Free Energy Landscapes of Proteins

National Institutes of Health

Grant: 1S10OD020095-01

Computer Cluster for Computational Biology and Biophysics

FWCI

2.04

Citation Percentile

0.9%

Citation Trend

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://doi.org/10.7554/elife.83368

publisherhttps://doi.org/10.7554/elife.83368

publisherhttps://cdn.elifesciences.org/articles/83368/elife-83368-v2.pdf

publisherhttps://cdn.elifesciences.org/articles/83368/elife-83368-v2.xml

publisherhttps://elifesciences.org/articles/83368

Fields of Study

Protein Structure and DynamicsComputational Drug Discovery MethodsEnzyme Structure and Function0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

Protein ConformationSerineThreonineTyrosineProtein Serine-Threonine KinasesProtein Kinase InhibitorsMolecular Dynamics Simulation

Keywords

ThreonineSerineKinaseDivergence (linguistics)Tyrosine kinaseProtein-Serine-Threonine KinasesTyrosineReceptor tyrosine kinaseFunctional divergencePhosphorylationSH3 domainBiochemistryProtein-Tyrosine KinasesCell biologyChemistryBiologySignal transductionProtein kinase AGeneGenomeprotein kinasesQH301-705.5Protein Conformationconformational landscapeScienceQfree-energy simulationsRProtein Serine-Threonine KinasesMolecular Dynamics SimulationcoevolutionMedicineBiology (General)Protein Kinase Inhibitorstype-II inhibitorstyrosine kinase evolutionComputational and Systems Biology

Sustainable Development Goals

SDG 0: Affordable and clean energy