Masahiro Kanai

Also affiliated with Harvard University, Massachusetts General Hospital, Tokyo Metropolitan Police Hospital, The University of Osaka

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

11.6Author DataRank

Indexed papers

8in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 8 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

A first update on mapping the human genetic architecture of COVID-19

Nature(2022)10.1038/s41586-022-04826-7

Top 6%

3.5DataRank

Top 6%176 citations

Leadership, Gita A. Pathak, Juha Karjalainen, Christine Stevens, Benjamin M. Neale +86 more

Papers

Driven by 59 papers — median percentile 90. Top paper: “The power of genetic diversity in genome-wide association studies of lipids”.

The power of genetic diversity in genome-wide association studies of lipids

Nature(2021)10.1038/s41586-021-04064-3

N/A

9.9DataRank · unranked

1069 citations

Shoa L. Clarke, Kuan-Han H. Wu, Stavroula Kanoni, Greg J. M. Zajac, Shweta Ramdas +95 more

A genomic mutational constraint map using variation in 76,156 human genomes

Nature(2023)10.1038/s41586-023-06045-0

N/A

9.6DataRank · unranked

1369 citations

Laurent C. Francioli, Julia K. Goodrich, Ryan L. Collins, Masahiro Kanai, Qingbo S. Wang +95 more

Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations

Cell(2020)10.1016/j.cell.2020.06.045

N/A

8.3DataRank · unranked

739 citations

Laura M. Raffield, Abdou Mousas, Saori Sakaue, Jennifer E. Huffman, Arden Moscati +95 more

Leveraging fine-mapping and multipopulation training data to improve cross-population polygenic risk scores

Nature Genetics(2022)10.1038/s41588-022-01036-9

N/A

6.6DataRank · unranked

284 citations

Masahiro Kanai, Huwenbo Shi, Steven Gazal, Wouter J. Peyrot, Amit V. Khera +30 more

A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response

Nature Genetics(2021)10.1038/s41588-021-00935-7

N/A

4.0DataRank · unranked

191 citations

Masahiro Kanai, Wanson Choi, Xinyi Li, Saori Sakaue, Kenichi Yamamoto +95 more

A first update on mapping the human genetic architecture of COVID-19

Nature(2022)10.1038/s41586-022-04826-7

Top 6%

3.5DataRank

Top 6%176 citations

Leadership, Gita A. Pathak, Juha Karjalainen, Christine Stevens, Benjamin M. Neale +86 more

Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases

medRxiv(2020)10.1101/2020.09.08.20190561

N/A

3.4DataRank · unranked

132 citations

Jacob C. Ulirsch, Nathan Y. Cheng, Brian L. Trippe, Rebecca S. Fine, Jenkai Miao +24 more

Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease

International Journal of Epidemiology(2021)10.1093/ije/dyab203

Top 7%

3.0DataRank

Top 7%122 citations

Yuemiao Zhang, Humaira Rasheed, Venexia Walker, Yuka Sugawara, Jiachen Li +38 more

Multi-ancestry meta-analysis of asthma identifies novel associations and highlights the value of increased power and diversity

Cell Genomics(2022)10.1016/j.xgen.2022.100212

N/A

2.4DataRank · unranked

118 citations

Wei Zhou, Ying Wang, Masahiro Kanai, Shinichi Namba, Rahul Gupta +8 more

Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference

Nature Genetics(2024)10.1038/s41588-023-01596-4

Top 9%

2.4DataRank

Top 9%176 citations

Georgina Navoly, Olga Giannakopoulou, Daniel F. Levey, Dóra Koller, Gita A. Pathak +76 more

Genome-wide risk prediction of common diseases across ancestries in one million people

Cell Genomics(2022)10.1016/j.xgen.2022.100118

N/A

2.3DataRank · unranked

93 citations

Sini Kerminen, Yen‐Chen Anne Feng, Masahiro Kanai, Kristi Läll, Laurent F. Thomas +15 more

Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features

Nature Communications(2020)10.1038/s41467-020-15022-4

N/A

2.0DataRank · unranked

81 citations

Carl G. de Boer, Charles P. Fulco, Caleb A. Lareau, Masahiro Kanai, Jacob C. Ulirsch +12 more

Analysis of genetic dominance in the UK Biobank

Science(2023)10.1126/science.abn8455

Top 12%

1.7DataRank

Top 12%72 citations

Wei Zhou, Liam Abbott, Emilie M. Wigdor, Nikolas Baya, Claire Churchhouse +7 more

Polygenic prediction across populations is influenced by ancestry, genetic architecture, and methodology

Cell Genomics(2023)10.1016/j.xgen.2023.100408

N/A

1.4DataRank · unranked

66 citations

Masahiro Kanai, Taotao Tan, Mireille Kamariza, Kristin Tsuo, Kai Yuan +7 more

Clinical use of current polygenic risk scores may exacerbate health disparities

Nature Genetics(2019)10.1038/s41588-019-0379-x

N/A

1.2DataRank · unranked

2850 citations

Masahiro Kanai, Yoichiro Kamatani, Karen L. Mohlke, Michael C O'Donovan, Coleen Damcott +1 more

Best practices for multi-ancestry, meta-analytic transcriptome-wide association studies: Lessons from the Global Biobank Meta-analysis Initiative

Cell Genomics(2022)10.1016/j.xgen.2022.100180

N/A

1.1DataRank · unranked

40 citations

Jibril Hirbo, Dan Zhou, Wei Zhou, Jie Zheng, Masahiro Kanai +4 more

Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases

Nature Genetics(2018)10.1038/s41588-018-0047-6

N/A

1.0DataRank · unranked

901 citations

Masato Akiyama, Atsushi Takahashi, Nana Matoba, Yukihide Momozawa, Masashi Ikeda +8 more

Leveraging supervised learning for functionally-informed fine-mapping of cis-eQTLs identifies an additional 20,913 putative causal eQTLs

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.20.347294

N/A

0.998DataRank · unranked

22 citations

David R. Kelley, Jacob C. Ulirsch, Masahiro Kanai, Shuvom Sadhuka, Ran Cui +9 more

The Polygenic and Monogenic Basis of Blood Traits and Diseases

Cell(2020)10.1016/j.cell.2020.08.008

N/A

0.988DataRank · unranked

722 citations

Erik L. Bao, Parsa Akbari, Caleb A. Lareau, Abdou Mousas, Tao Jiang +95 more

Tissue-specific enhancer–gene maps from multimodal single-cell data identify causal disease alleles

Nature Genetics(2024)10.1038/s41588-024-01682-1

N/A

0.972DataRank · unranked

52 citations

Kathryn Weinand, Shakson Isaac, Kushal K. Dey, Karthik A. Jagadeesh, Masahiro Kanai +86 more

Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases

Nature Genetics(2023)10.1038/s41588-023-01443-6

N/A

0.853DataRank · unranked

293 citations

Jacob C. Ulirsch, Nathan Y. Cheng, Brian L. Trippe, Rebecca S. Fine, Jenkai Miao +23 more

Functional dissection of complex and molecular trait variants at single nucleotide resolution

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.05.05.592437

N/A

0.821DataRank · unranked

31 citations

Rodrigo Castro, Hannah B. Dewey, Susan Kales, Thanh Thanh L. Nguyen, Masahiro Kanai +19 more

Nuclear genetic control of mtDNA copy number and heteroplasmy in humans

Nature(2023)10.1038/s41586-023-06426-5

N/A

0.785DataRank · unranked

187 citations

Masahiro Kanai, Timothy Durham, Kristin Tsuo, Jason G. McCoy, Anna V. Kotrys +7 more

Pan-UK Biobank GWAS improves discovery, analysis of genetic architecture, and resolution into ancestry-enriched effects

medRxiv(2024)10.1101/2024.03.13.24303864

N/A

0.774DataRank · unranked

173 citations

Rahul Gupta, Masahiro Kanai, Wenhan Lu, Kristin Tsuo, Ying Wang +24 more

Population-specific causal disease effect sizes in functionally important regions impacted by selection

Nature Communications(2021)10.1038/s41467-021-21286-1

N/A

0.741DataRank · unranked

139 citations

Steven Gazal, Masahiro Kanai, Evan M. Koch, Armin Schoech, Katherine M. Siewert +9 more

Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts

Cell Genomics(2023)10.1016/j.xgen.2022.100241

N/A

0.710DataRank · unranked

113 citations

Shinichi Namba, Esteban A. Lopera-Maya, Sini Kerminen, Kristin Tsuo, Kristi Läll +83 more

A high-resolution HLA reference panel capturing global population diversity enables multi-ethnic fine-mapping in HIV host response

medRxiv(2020)10.1101/2020.07.16.20155606

Top 28%

0.708DataRank

Top 28%15 citations

Masahiro Kanai, Wanson Choi, Xinyi Li, Kenichi Yamamoto, Kotaro Ogawa +24 more

Leveraging supervised learning for functionally informed fine-mapping of cis-eQTLs identifies an additional 20,913 putative causal eQTLs

Nature Communications(2021)10.1038/s41467-021-23134-8

N/A

0.694DataRank · unranked

101 citations

David R. Kelley, Jacob C. Ulirsch, Masahiro Kanai, Shuvom Sadhuka, Ran Cui +33 more

Meta-analysis fine-mapping is often miscalibrated at single-variant resolution

Cell Genomics(2022)10.1016/j.xgen.2022.100210

N/A

0.670DataRank · unranked

86 citations

Roy Elzur, Wei Zhou, Kuan-Han Wu, Humaira Rasheed, Kristin Tsuo +91 more

Improving fine-mapping by modeling infinitesimal effects

Nature Genetics(2023)10.1038/s41588-023-01597-3

N/A

0.635DataRank · unranked

68 citations

Roy Elzur, Masahiro Kanai, Jacob C. Ulirsch, Omer Weissbrod, Mark J. Daly +4 more

Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis

Genome biology(2022)10.1186/s13059-022-02837-1

N/A

0.626DataRank · unranked

64 citations

Sarah E. Graham, Yuxuan Wang, Ida Surakka, Shweta Ramdas, Xiang Zhu +95 more

A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids

The American Journal of Human Genetics(2022)10.1016/j.ajhg.2022.06.012

N/A

0.626DataRank · unranked

64 citations

Jonathan Judd, Sarah E. Graham, Stavroula Kanoni, Yuxuan Wang, Ida Surakka +95 more

Narcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy

Nature Communications(2023)10.1038/s41467-023-36120-z

N/A

0.621DataRank · unranked

62 citations

Eilon Sharon, Ling Lin, Nicholas A. Sinnott-Armstrong, Aditya Ambati, Selina Yogeshwar +95 more

SARS-CoV-2 susceptibility and COVID-19 disease severity are associated with genetic variants affecting gene expression in a variety of tissues

Cell Reports(2021)10.1016/j.celrep.2021.110020

N/A

0.581DataRank · unranked

47 citations

Jennifer Nguyen, Timothy D. Arthur, Hiroko Matsui, Agnieszka D’Antonio‐Chronowska, Kelly A. Frazer +85 more

Current clinical use of polygenic scores will risk exacerbating health disparities

bioRxiv (Cold Spring Harbor Laboratory)(2018)10.1101/441261

N/A

0.568DataRank · unranked

43 citations

Masahiro Kanai, Yoichiro Kamatani, Karen L. Mohlke, Michael C O'Donovan, Coleen Damcott +1 more

Principled distillation of UK Biobank phenotype data reveals underlying structure in human variation

Nature Human Behaviour(2024)10.1038/s41562-024-01909-5

N/A

0.564DataRank · unranked

18 citations

Rebecca Shafee, Robbee Wedow, Amanda Elliott, Duncan S. Palmer, John Compitello +14 more

Genome-wide association study of long COVID

Nature Genetics(2025)10.1038/s41588-025-02100-w

N/A

0.550DataRank · unranked

38 citations

Tomoko Nakanishi, Samuel E. Jones, Shea J. Andrews, Juha Karjalainen, Beatriz Cortés +95 more

Polygenic prediction across populations is influenced by ancestry, genetic architecture, and methodology

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.12.29.522270

N/A

0.519DataRank · unranked

10 citations

Masahiro Kanai, Taotao Tan, Mireille Kamariza, Kristin Tsuo, Kai Yuan +8 more

Novel ancestry-specific primary open-angle glaucoma loci and shared biology with vascular mechanisms and cell proliferation

Cell Reports Medicine(2024)10.1016/j.xcrm.2024.101430

N/A

0.510DataRank · unranked

29 citations

Arjun Bhattacharya, Wei Zhou, Dan Zhou, Ying Wang, Kristi Läll +31 more

Global biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts

medRxiv(2021)10.1101/2021.11.18.21266545

N/A

0.489DataRank · unranked

25 citations

Shinichi Namba, Esteban A. Lopera-Maya, Sini Kerminen, Kristin Tsuo, Kristi Läll +25 more

Blood DNA virome associates with autoimmune diseases and COVID-19

Nature Genetics(2025)10.1038/s41588-024-02022-z

N/A

0.457DataRank · unranked

20 citations

Shohei Kojima, Rie Koide, Takanori Hasegawa, Ho Namkoong, Tomomitsu Hirota +95 more

Tissue-specific enhancer-gene maps from multimodal single-cell data identify causal disease alleles

medRxiv(2022)10.1101/2022.10.27.22281574

N/A

0.425DataRank · unranked

16 citations

Kathryn Weinand, Shakson Isaac, Kushal K. Dey, Karthik A. Jagadeesh, Masahiro Kanai +10 more

Author Correction: The power of genetic diversity in genome-wide association studies of lipids

Nature(2023)10.1038/s41586-023-06194-2

N/A

0.416DataRank · unranked

15 citations

Shoa L. Clarke, Kuan-Han H. Wu, Stavroula Kanoni, Greg J. M. Zajac, Shweta Ramdas +95 more

Best practices for multi-ancestry, meta-analytic transcriptome-wide association studies: lessons from the Global Biobank Meta-analysis Initiative

medRxiv(2021)10.1101/2021.11.24.21266825

N/A

0.373DataRank · unranked

11 citations

Jibril Hirbo, Dan Zhou, Wei Zhou, Jie Zheng, Masahiro Kanai +5 more

Multi-ancestry GWAS of major depression aids locus discovery, fine-mapping, gene prioritisation, and causal inference

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.20.500802

Top 54%

0.311DataRank

Top 54%4 citations

Georgina Navoly, Olga Giannakopoulou, Daniel F. Levey, Dóra Koller, Gita A. Pathak +71 more

Principled distillation of multidimensional UK Biobank data reveals insights into the correlated human phenome

medRxiv(2022)10.1101/2022.09.02.22279546

N/A

0.294DataRank · unranked

4 citations

Rebecca Shafee, Amanda Elliott, Duncan S. Palmer, John Compitello, Masahiro Kanai +14 more

Large-scale genome-wide analyses with proteomics integration reveal novel loci and biological insights into frailty

Nature Aging(2025)10.1038/s43587-025-00925-y

N/A

0.269DataRank · unranked

5 citations

Chenxi Qin, Moritz Krüger, Anna Kuukka, Aarno Palotie, Mark Daly +322 more

Author Correction: A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response

Nature Genetics(2021)10.1038/s41588-021-00979-9

N/A

0.246DataRank · unranked

4 citations

Masahiro Kanai, Wanson Choi, Xinyi Li, Saori Sakaue, Kenichi Yamamoto +95 more

Genome-wide Screen of Otosclerosis in Population Biobanks: 18 Loci and Shared Heritability with Skeletal Structure

medRxiv(2020)10.1101/2020.11.15.20227868

N/A

0.241DataRank · unranked

4 citations

Tuomo Kiiskinen, Juha Karjalainen, Kristi Krebs, Mitja Kurki, Aki S. Havulinna +17 more

Trans-ethnic Mendelian randomization study reveals causal relationships between cardio-metabolic factors and chronic kidney disease

medRxiv(2020)10.1101/2020.09.04.20188284

N/A

0.165DataRank · unranked

2 citations

YueMiao Zhang, Humaira Rasheed, Venexia Walker, Yuka Sugawara, Jiachen Li +38 more

The centrosomal protein FGFR1OP controls myosin function in murine intestinal epithelial cells

Developmental Cell(2024)10.1016/j.devcel.2024.06.001

N/A

0.165DataRank · unranked

2 citations

Vincent Peng, Chirag Krishna, Takahiro E. Ohara, Wandy L. Beatty, Raki Sudan +16 more

Leveraging fine-scale population structures for precision healthcare

Nature Medicine(2023)10.1038/s41591-023-02423-3

N/A

0.104DataRank · unranked

1 citations

Masahiro Kanai

Systematic visualisation of molecular QTLs reveals variant mechanisms at GWAS loci

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.06.535816

N/A

0.104DataRank · unranked

1 citations

Ralf Tambets, James Hayhurst, Ida Rahu, Peep Kolberg, Uku Raudvere +18 more

Responsible use of polygenic risk scores in the clinic: potential benefits, risks and gaps

Nature Medicine(2021)10.1038/s41591-021-01549-6

N/A

0DataRank · unranked

445 citations

Adebowale Adeyemo, Mary K. Balaconis, Deanna R. Darnes, Segun Fatumo, Palmira Granados Moreno +22 more

Genome-wide functional screen of 3′UTR variants uncovers causal variants for human disease and evolution

Cell(2021)10.1016/j.cell.2021.08.025

N/A

0DataRank · unranked

188 citations

James R. Xue, Steven K. Reilly, Jacob C. Ulirsch, Kalki Kukreja, Joe R. Davis +11 more

Leveraging fine-mapping and non-European training data to improve cross-population polygenic risk scores

medRxiv(2021)10.1101/2021.01.19.21249483

N/A

0DataRank · unranked

31 citations

Masahiro Kanai, Huwenbo Shi, Steven Gazal, Wouter J. Peyrot, Amit V. Khera +6 more

Widespread naturally variable human exons aid genetic interpretation

Nature Communications(2025)10.1038/s41467-025-65476-7

N/A

0DataRank · unranked

0 citations

Bram L. Gorissen, Jérémy Guez, Masahiro Kanai, Kavi Gupta, Hilary K. Finucane +3 more

Meta-analysis fine-mapping is often miscalibrated at single-variant resolution

medRxiv(2022)10.1101/2022.03.16.22272457

N/A

0DataRank · unranked

48 citations

Roy Elzur, Wei Zhou, Global Biobank Meta-analysis Initiative, Mark J. Daly, Hilary K. Finucane +1 more

A Cross-Trait Genetic Correlation Study Identified Eight Diseases and Traits Associated with Psoriasis

Journal of Investigative Dermatology(2023)10.1016/j.jid.2023.01.037

N/A

0DataRank · unranked

2 citations

Lam C. Tsoi, Hiroaki Tanaka, Masahiro Kanai, Philip E. Stuart, Rajan P. Nair +5 more

Masahiro Kanai

Indexed papers

Top data-sharing exemplar

Papers