Nathanael S. Gray

Also affiliated with Nuffield Orthopaedic Centre, University of Oxford, Dana-Farber Cancer Institute, Stanford Medicine, Stanford University

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 2%percentile

1.9Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification

International Journal of Molecular Sciences(2021)10.3390/ijms22020566

Top 11%

1.9DataRank

Top 11%110 citations

Hassan Al‐Ali, David Andrews, Christopher R. M. Asquith, Alison D. Axtman, Ivan Đikić +25 more

Papers

Driven by 113 papers — median percentile 89. Top paper: “Molecular basis for cooperative binding and synergy of ATP-site and allosteric EGFR inhibitors”.

Molecular basis for cooperative binding and synergy of ATP-site and allosteric EGFR inhibitors

Nature Communications(2022)10.1038/s41467-022-30258-y

N/A

2.0DataRank · unranked

88 citations

Ciric To, David E. Heppner, Jaimin K. Rana, Anna M. Schmoker, Jaebong Jang +7 more

The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification

International Journal of Molecular Sciences(2021)10.3390/ijms22020566

Top 11%

1.9DataRank

Top 11%110 citations

Hassan Al‐Ali, David Andrews, Christopher R. M. Asquith, Alison D. Axtman, Ivan Đikić +25 more

SYK is activated by mutated MYD88 and drives pro-survival signaling in MYD88 driven B-cell lymphomas

Blood Cancer Journal(2020)10.1038/s41408-020-0277-6

N/A

1.4DataRank · unranked

48 citations

Xia Liu, Jiaji G. Chen, Lian Xu, Nickolas Tsakmaklis, Maria Demos +19 more

Structure-Based Design of Y-Shaped Covalent TEAD Inhibitors

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.2c01548

N/A

1.3DataRank · unranked

47 citations

Mengyang Fan, Wenzhi Ji, Jason Tse, Inchul You, Scott B. Ficarro +16 more

Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway

Cancer Cell(2020)10.1016/j.ccell.2019.12.006

N/A

0.925DataRank · unranked

477 citations

Yao Liu, Ciric To, Tinghu Zhang, Mengyang Fan, Amir Vajdi +39 more

A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Aging

Cell(2020)10.1016/j.cell.2020.02.012

N/A

0.908DataRank · unranked

424 citations

Mark P. Jedrychowski, Devin K. Schweppe, Edward L. Huttlin, Qing Yu, David E. Heppner +15 more

Rewiring cancer drivers to activate apoptosis

Nature(2023)10.1038/s41586-023-06348-2

N/A

0.768DataRank · unranked

166 citations

A. Krokhotin, Wenzhi Ji, Xiaofan Liu, Chiung-Ying Chang, Samuel H. Kim +10 more

Functional Genomics Identify Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins

Cell Reports(2021)10.1016/j.celrep.2020.108532

N/A

0.716DataRank · unranked

117 citations

Geoffrey M. Matthews, Sara Gandolfi, Ricardo De Matos Simoes, Dennis L. Buckley, Joseline Raja +34 more

Cereblon covalent modulation through structure-based design of histidine targeting chemical probes

RSC Chemical Biology(2022)10.1039/d2cb00078d

N/A

0.646DataRank · unranked

73 citations

Geoffrey P. Dann, Jianwei Che, Katherine A. Donovan, Silas Ferrao, Scott B. Ficarro +11 more

Chemical Specification of E3 Ubiquitin Ligase Engagement by Cysteine-Reactive Chemistry

Journal of the American Chemical Society(2023)10.1021/jacs.3c06622

N/A

0.637DataRank · unranked

69 citations

Inchul You, Yen-Der Li, Sean T. Toenjes, Katherine A. Donovan, Pooreum Seo +11 more

Discovery of a Potent Degrader for Fibroblast Growth Factor Receptor 1/2

Angewandte Chemie International Edition(2021)10.1002/anie.202101328

N/A

0.612DataRank · unranked

58 citations

Jie Jiang, Qibiao Wu, Nathaniel J. Henning, Katherine A. Donovan, Hong Yue +7 more

Unveiling the hidden interactome of CRBN molecular glues

Nature Communications(2025)10.1038/s41467-025-62099-w

N/A

0.590DataRank · unranked

50 citations

Rebecca J. Metivier, Shourya S. Roy Burman, Jonathan W. Bushman, Hojong Yoon, Ryan J. Lumpkin +13 more

Depletion of creatine phosphagen energetics with a covalent creatine kinase inhibitor

Nature Chemical Biology(2023)10.1038/s41589-023-01273-x

N/A

0.584DataRank · unranked

48 citations

Wenzhi Ji, Mengyang Fan, Shan Lin, Hyuk‐Soo Seo, Ekaterina V. Vinogradova +15 more

Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias

Nature Cancer(2023)10.1038/s43018-023-00550-x

N/A

0.568DataRank · unranked

43 citations

Ryosuke Shirasaki, Sondra L. Downey-Kopyscinski, Geoffrey M. Matthews, Benjamin G. Barwick, Vikas A. Gupta +36 more

Targeted kinase degradation via the KLHDC2 ubiquitin E3 ligase

Cell chemical biology(2023)10.1016/j.chembiol.2023.07.008

N/A

0.538DataRank · unranked

35 citations

Pooreum Seo, Eunhye Jeon, Inchul You, Kyubin Hwang, Namkyoung Kim +7 more

PRM-LIVE with Trapped Ion Mobility Spectrometry and Its Application in Selectivity Profiling of Kinase Inhibitors

Analytical Chemistry(2021)10.1021/acs.analchem.1c02349

N/A

0.520DataRank · unranked

31 citations

Scott B. Ficarro, William M. Alexander, Laura E. Fleming, Guillaume Adelmant, Tinghu Zhang +10 more

The HCK/BTK inhibitor KIN-8194 is active in MYD88-driven lymphomas and overcomes mutated BTKCys481 ibrutinib resistance

Blood(2021)10.1182/blood.2021011405

N/A

0.505DataRank · unranked

28 citations

Jinhua Wang, Li Tan, Manit Munshi, Xia Liu, Amanda Kofides +17 more

Development of a Covalent Inhibitor of c-Jun N-Terminal Protein Kinase (JNK) 2/3 with Selectivity over JNK1

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.2c01834

N/A

0.500DataRank · unranked

27 citations

Yao Liu, Yang Gao, Qixiang Geng, Deepak Gurbani, Lianbo Li +17 more

Selective degradation-inducing probes for studying cereblon (CRBN) biology

RSC Medicinal Chemistry(2021)10.1039/d0md00382d

N/A

0.500DataRank · unranked

27 citations

Guangyan Du, Jonathan W. Bushman, Zhixiang He, Tinghu Zhang, Eric S. Fischer +2 more

Metabolic and Functional Genomic Studies Identify Deoxythymidylate Kinase as a Target in LKB1-Mutant Lung Cancer

UNC Libraries(2020)10.17615/ge7q-0q17

N/A

0.442DataRank · unranked

18 citations

Sean T. Bailey, David J. Kwiatkowski, Pasi A. Jänne, Jeffrey A. Engelman, Julián Carretero +35 more

Targeting transcription in heart failure via CDK7/12/13 inhibition

Nature Communications(2022)10.1038/s41467-022-31541-8

N/A

0.425DataRank · unranked

16 citations

Qiming Duan, Daniel S. Day, Xin Luo, Sarah McMahon, Yu Huang +13 more

A new role for the SRC family kinase HCK as a driver of SYK activation in MYD88 mutated lymphomas

Blood Advances(2022)10.1182/bloodadvances.2021006147

N/A

0.416DataRank · unranked

15 citations

Xia Liu, Amanda Kofides, Nickolas Tsakmaklis, Maria Luisa Guerrera, Zachary R. Hunter +18 more

Development of potent and selective degraders of PI5P4Kγ

European Journal of Medicinal Chemistry(2022)10.1016/j.ejmech.2022.115027

N/A

0.373DataRank · unranked

11 citations

Eric S. Wang, Theresa Manz, Jie Jiang, Katherine A. Donovan, Xianmixinuer Abulaiti +5 more

Discovery of Potent Degraders of the Dengue Virus Envelope Protein

Advanced Science(2024)10.1002/advs.202405829

N/A

0.373DataRank · unranked

11 citations

Han‐Yuan Liu, Zhixiang He, Antara Chakravarty, Ryan P. Golden, Zixuan Jiang +13 more

Rewiring Cancer Drivers to Activate Apoptosis

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.12.04.517548

N/A

0.330DataRank · unranked

8 citations

A. Krokhotin, Wenzhi Ji, Xiaofan Liu, Chiung-Ying Chang, Samuel H. Kim +7 more

Sulfopin, a selective covalent inhibitor of Pin1, blocks Myc-driven tumor initiation and growth in vivo

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.20.998443

N/A

0.330DataRank · unranked

8 citations

Benika J. Pinch, Daniel Zaidman, Theresa Manz, Evon Poon, Shuning He +33 more

Discovery of electrophilic degraders that exploit SNAr chemistry

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.25.615094

N/A

0.292DataRank · unranked

6 citations

Woong Sub Byun, Zuzanna Kozicka, Brendan G. Dwyer, Katherine A. Donovan, Zixuan Jiang +9 more

Proteomics‐Based Discovery of First‐in‐Class Chemical Probes for Programmed Cell Death Protein 2 (PDCD2)

Angewandte Chemie International Edition(2023)10.1002/anie.202308292

N/A

0.269DataRank · unranked

5 citations

Woong Sub Byun, Wenchao Lu, Xijun Zhu, Katherine A. Donovan, Brendan G. Dwyer +8 more

ZNL0325, a Pyrazolopyrimidine-Based Covalent Probe, Demonstrates an Alternative Binding Mode for Kinases

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.3c01891

N/A

0.241DataRank · unranked

4 citations

Wenchao Lu, Tyler S. Beyett, Scott B. Ficarro, Jie Jiang, Jason Tse +8 more

Borrowing Transcriptional Kinases to Activate Apoptosis

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.23.563687

N/A

0.241DataRank · unranked

4 citations

Sai Gourisankar, Basel A. Karim, Sabin A. Nettles, Haopeng Yang, Brendan G. Dwyer +10 more

Integrative Proteogenomics and Forward Genetics Reveal a Novel Mitotic Vulnerability in Triple-Negative Breast Cancer

Cancer Discovery(2025)10.1158/2159-8290.cd-23-1173

N/A

0.208DataRank · unranked

3 citations

Shankha Satpathy, Karsten Krug, Jitendra K. Meena, Nivetha Ramesh Babu, Cheyenne Calderon +51 more

Development and utility of a PAK1-selective degrader

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.12.491715

N/A

0.165DataRank · unranked

2 citations

Sofiia Karchugina, Brian J. Groendyke, Sean T. Toenjes, John M. Hatcher, Katherine A. Donovan +7 more

Development of Degraders and 2-pyridinecarboxyaldehyde (2-PCA) as a recruitment Ligand for FBXO22

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.19.671158

N/A

0.104DataRank · unranked

1 citations

Zhe Zhuang, Woong Sub Byun, Zuzanna Kozicka, Kheewoong Baek, Jianing Zhong +7 more

Temporal resolution of gene derepression and proteome changes upon PROTAC-mediated degradation of BCL11A protein in erythroid cells

Cell chemical biology(2022)10.1016/j.chembiol.2022.06.007

N/A

0DataRank · unranked

45 citations

Altantsetseg Buyanbat, Kai Yan, Ozge Karayel, Seth Goldman, Davide Seruggia +12 more

Development and Utility of a PAK1-Selective Degrader

Journal of Medicinal Chemistry(2022)10.1021/acs.jmedchem.2c00756

N/A

0DataRank · unranked

31 citations

Sofiia Karchugina, Brian J. Groendyke, Sean T. Toenjes, John M. Hatcher, Katherine A. Donovan +7 more

A Novel HER2-Selective Kinase Inhibitor Is Effective in HER2 Mutant and Amplified Non–Small Cell Lung Cancer

Cancer Research(2022)10.1158/0008-5472.can-21-2693

N/A

0DataRank · unranked

36 citations

Jaebong Jang, Tyler S. Beyett, Yoonji Eum, Heidi M. Haikala, Alyssa Verano +13 more

Synergistic Anti-Tumor Effect of Combining Selective CDK7 and BRD4 Inhibition in Neuroblastoma

Frontiers in Oncology(2022)10.3389/fonc.2021.773186

N/A

0DataRank · unranked

24 citations

Marina P. Volegova, Nicole Nasholm, Sanjukta Das, Nicholas Kwiatkowski, Brian J. Abraham +6 more

Quinazolinones as allosteric fourth-generation EGFR inhibitors for the treatment of NSCLC

Bioorganic & Medicinal Chemistry Letters(2022)10.1016/j.bmcl.2022.128718

N/A

0DataRank · unranked

23 citations

David E. Heppner, Tyler S. Beyett, Ciric To, Seth C. Azevedo, Jaebong Jang +11 more

Anti‐SARS‐CoV‐2 activity of targeted kinase inhibitors: Repurposing clinically available drugs for COVID‐19 therapy

Journal of Medical Virology(2022)10.1002/jmv.28157

N/A

0DataRank · unranked

22 citations

Mikołaj Słabicki, Sita Ramaswamy, J. J. Patten, Charles Zou, Chengcheng Meng +12 more

Transcriptional Antagonism by CDK8 Inhibition Improves Therapeutic Efficacy of MEK Inhibitors

Cancer Research(2022)10.1158/0008-5472.can-21-4309

N/A

0DataRank · unranked

17 citations

Minjee Kim, Gabriela Alexe, Kathleen Engel, Alexandra B. Forman, Amanda L. Robichaud +10 more

A preclinical platform for assessing antitumor effects and systemic toxicities of cancer drug targets

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2110557119

N/A

0DataRank · unranked

14 citations

Chun‐Hao Huang, Francisco J. Sánchez‐Rivera, Margaret C. Kennedy, Darjus F. Tschaharganeh, John P. Morris +15 more

Novel Macrocyclic Peptidomimetics Targeting the Polo-Box Domain of Polo-Like Kinase 1

Journal of Medicinal Chemistry(2022)10.1021/acs.jmedchem.1c01359

N/A

0DataRank · unranked

8 citations

Jung‐Eun Park, Young Jin Ham, Daniel Lim, Nicholas Kwiatkowski, Do‐Hee Kim +13 more

Targeted Kinase Degradation via the KLHDC2 Ubiquitin E3 Ligase

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.12.17.520883

N/A

0DataRank · unranked

5 citations

Christina Seo, Eunhye Jeon, Inchul You, Kyubin Hwang, Namkyoung Kim +5 more

Multi-omic profiling of breast cancer cells uncovers stress MAPK-associated sensitivity to AKT degradation

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.11.511726

N/A

0DataRank · unranked

2 citations

Inchul You, Grace E. Perry, Aurelien Dugourd, Katherine A. Donovan, Claire Crafter +11 more

Genome-Wide CRISPR Screens Identify Multiple Synthetic Lethal Targets That Enhance KRASG12C Inhibitor Efficacy

Cancer Research(2023)10.1158/0008-5472.can-23-2729

N/A

0DataRank · unranked

106 citations

Hsin‐Yi Huang, Ziyan Lin, Michela Ranieri, Shuai Li, Soumyadip Sahu +21 more

The ETS transcription factor ETV6 constrains the transcriptional activity of EWS–FLI to promote Ewing sarcoma

Nature Cell Biology(2023)10.1038/s41556-022-01059-8

N/A

0DataRank · unranked

43 citations

Jana M. Ellegast, Kenneth N. Ross, Clare F. Malone, Shan Lin, Nathaniel W. Mabe +14 more

Catalytic Degraders Effectively Address Kinase Site Mutations in EML4-ALK Oncogenic Fusions

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.2c01864

N/A

0DataRank · unranked

42 citations

Baishan Jiang, Hellen Kim, Matthew J. Berberich, Jianwei Che, Katherine A. Donovan +13 more

Targeting the Dark Lipid Kinase PIP4K2C with a Potent and Selective Binder and Degrader

Angewandte Chemie International Edition(2023)10.1002/anie.202302364

N/A

0DataRank · unranked

8 citations

Jie Jiang, Eric S. Wang, Qixiang Geng, Sean T. Toenjes, Katherine A. Donovan +9 more

Human Polo-like Kinase Inhibitors as Antiplasmodials

ACS Infectious Diseases(2023)10.1021/acsinfecdis.3c00025

N/A

0DataRank · unranked

8 citations

Jinhua Wang, Eva S. Istvan, Madeline R. Luth, Jennifer E. Collins, Edward L. Huttlin +12 more

Development of Mutant-Selective Allosteric EGFR Inhibitors for Drug-Resistant Lung Cancer

Journal of Pharmacology and Experimental Therapeutics(2023)10.1124/jpet.122.162040

N/A

0DataRank · unranked

1 citations

Ciric To, David E. Heppner, Thomas W. Gero, Nathanael S. Gray, David A. Scott +3 more

Template-assisted covalent modification of DCAF16 underlies activity of BRD4 molecular glue degraders

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.14.528208

N/A

0DataRank · unranked

45 citations

W Michelle, Muhammad Murtaza Hassan, Moritz Hunkeler, Mingxing Teng, Kedar Puvar +23 more

Exploration of the Tunability of BRD4 Degradation by DCAF16 Trans -labelling Covalent Glues

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.07.561308

N/A

0DataRank · unranked

10 citations

Yen-Der Li, W Michelle, Mingxing Teng, Woong Sub Byun, Kedar Puvar +14 more

Data from A High-Throughput Immune-Oncology Screen Identifies EGFR Inhibitors as Potent Enhancers of Antigen-Specific Cytotoxic T-lymphocyte Tumor Cell Killing

(2023)10.1158/2326-6066.c.6549088.v1

N/A

0DataRank · unranked

0 citations

Ruey‐Long Hong, Troy A. Luster, Megan E. Cavanaugh, Luke J. Taus, Stephen Wang +14 more

Proteomics‐Based Discovery of First‐in‐Class Chemical Probes for Programmed Cell Death Protein 2 (PDCD2)

Angewandte Chemie(2023)10.1002/ange.202308292

N/A

0DataRank · unranked

0 citations

Woong Sub Byun, Wenchao Lu, Xijun Zhu, Katherine A. Donovan, Brendan G. Dwyer +8 more

Template-assisted covalent modification underlies activity of covalent molecular glues

Nature Chemical Biology(2024)10.1038/s41589-024-01668-4

N/A

0DataRank · unranked

93 citations

W Michelle, Muhammad Murtaza Hassan, Moritz Hunkeler, Mingxing Teng, Kedar Puvar +30 more

Relocalizing transcriptional kinases to activate apoptosis

Science(2024)10.1126/science.adl5361

N/A

0DataRank · unranked

58 citations

Sai Gourisankar, Basel A. Karim, Sabin A. Nettles, Haopeng Yang, Brendan G. Dwyer +10 more

Discovery of CRBN-Dependent WEE1 Molecular Glue Degraders from a Multicomponent Combinatorial Library

Journal of the American Chemical Society(2024)10.1021/jacs.4c06127

N/A

0DataRank · unranked

45 citations

Zixuan Jiang, Kheewoong Baek, Inchul You, Qixiang Geng, Katherine A. Donovan +11 more

Exploration of the tunability of BRD4 degradation by DCAF16 trans-labelling covalent glues

European Journal of Medicinal Chemistry(2024)10.1016/j.ejmech.2024.116904

N/A

0DataRank · unranked

35 citations

Yen-Der Li, W Michelle, Mingxing Teng, Woong Sub Byun, Kedar Puvar +14 more

Broad-spectrum activity against mosquito-borne flaviviruses achieved by a targeted protein degradation mechanism

Nature Communications(2024)10.1038/s41467-024-49161-9

N/A

0DataRank · unranked

24 citations

Zhengnian Li, Theresia Reindl, Zhixiang He, Xueer Qiu, Ryan P. Golden +7 more

Molecular Bidents with Two Electrophilic Warheads as a New Pharmacological Modality

ACS Central Science(2024)10.1021/acscentsci.3c01245

N/A

0DataRank · unranked

15 citations

Jie Jiang, Scott B. Ficarro, Tyler S. Beyett, Ciric To, Isidoro Tavares +9 more

Multiomic profiling of breast cancer cells uncovers stress MAPK-associated sensitivity to AKT degradation

Science Signaling(2024)10.1126/scisignal.adf2670

N/A

0DataRank · unranked

13 citations

Inchul You, Grace E. Perry, Aurelien Dugourd, Katherine A. Donovan, Claire Crafter +11 more

Discovery of Potent Antimalarial Type II Kinase Inhibitors with Selectivity over Human Kinases

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.3c02046

N/A

0DataRank · unranked

8 citations

Monica J. Bohmer, Jinhua Wang, Flore Nardella, Jaeson Calla, Mariana Laureano de Souza +14 more

Down-Regulation of AKT Proteins Slows the Growth of Mutant-KRAS Pancreatic Tumors

Cells(2024)10.3390/cells13121061

N/A

0DataRank · unranked

8 citations

Yaping Jiang, Inchul You, Nathanael S. Gray, Richard Z. Lin, Chuankai Chen

Discovery of bivalent small molecule degraders of cyclin-dependent kinase 7 (CDK7)

European Journal of Medicinal Chemistry(2024)10.1016/j.ejmech.2024.116613

N/A

0DataRank · unranked

7 citations

Guangyan Du, Jie Jiang, Wenchao Lu, Caitlin E. Mills, Linjie Yuan +10 more

Disrupting the RNA polymerase II transcription cycle through CDK7 inhibition ameliorates inflammatory arthritis

Science Translational Medicine(2024)10.1126/scitranslmed.adq5091

N/A

0DataRank · unranked

7 citations

Gayathri Shibu, Baila A. Sokolsky, Tamar Nicole Soussana, Logan Fisher, Dinesh K. Deochand +12 more

Synthesis and structure activity relationships of DCLK1 kinase inhibitors based on a 5,11-dihydro-6H-benzo[e]pyrimido[5,4-b] [1,4]diazepin-6-one scaffold

Figshare(2024)10.17615/8hj7-0260

N/A

0DataRank · unranked

4 citations

Stephen J. Capuzzi, Kenneth D. Westover, Eugene Muratov, Jinhua Wang, Wayne Harshbarger +7 more

Unveiling the hidden interactome of CRBN molecular glues with chemoproteomics

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.11.612438

N/A

0DataRank · unranked

20 citations

Rebecca J. Metivier, Shourya S. Roy Burman, Jonathan W. Bushman, Hojong Yoon, Ryan J. Lumpkin +9 more

Discovery of Potent Degraders of the Dengue Virus Envelope Protein

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.06.01.596987

N/A

0DataRank · unranked

6 citations

Han‐Yuan Liu, Zhixiang He, Antara Chakravarty, Ryan P. Golden, Zixuan Jiang +13 more

Activating p53 Y220C with a Mutant-Specific Small Molecule

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.10.23.619961

N/A

0DataRank · unranked

4 citations

Woong Sub Byun, Dominika Ewa Pieńkowska, Kha The Nguyen, Jan Gerhartz, Qixiang Geng +11 more

Rational Design of CDK12/13 and BRD4 Molecular Glue Degraders

Angewandte Chemie International Edition(2025)10.1002/anie.202508427

N/A

0DataRank · unranked

16 citations

Woong Sub Byun, Zuzanna Kozicka, Katherine A. Donovan, Brendan G. Dwyer, Abby M. Thornhill +7 more

Development of Potent and Selective CK1α Molecular Glue Degraders

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.4c02415

N/A

0DataRank · unranked

14 citations

Zixuan Jiang, Woong Sub Byun, Katherine A. Donovan, Zhe Zhuang, Fen Jiang +9 more

Expanding the druggable zinc-finger proteome defines properties of drug-induced degradation

Molecular Cell(2025)10.1016/j.molcel.2025.07.019

N/A

0DataRank · unranked

13 citations

Jiho Park, Radosław P. Nowak, Shourya S. Roy Burman, Jesse Pellman, Charles Zou +23 more

Discovery of BRD9 Molecular Glue Degraders That Spare Cardiomyocytes

Journal of the American Chemical Society(2025)10.1021/jacs.5c09857

N/A

0DataRank · unranked

13 citations

Zhe Zhuang, Anna P. Hnatiuk, Cyrus Y. Jin, Zixuan Jiang, Kheewoong Baek +6 more

Plasmodium falciparum protein kinase 6 and hemozoin formation are inhibited by a type II human kinase inhibitor exhibiting antimalarial activity

Cell chemical biology(2025)10.1016/j.chembiol.2025.06.003

N/A

0DataRank · unranked

9 citations

Tiantian Jiang, Lushun Wang, Monica J. Bohmer, Subhoja Chakraborty, John Okombo +32 more

Development of FBXO22 Degraders and the Recruitment Ligand 2-Pyridinecarboxyaldehyde (2-PCA)

Journal of the American Chemical Society(2025)10.1021/jacs.5c14141

N/A

0DataRank · unranked

7 citations

Zhe Zhuang, Woong Sub Byun, Zuzanna Kozicka, Kheewoong Baek, Jianing Zhong +7 more

Defining the Antitumor Mechanism of Action of a Clinical-stage Compound as a Selective Degrader of the Nuclear Pore Complex

Cancer Discovery(2025)10.1158/2159-8290.cd-25-0271

N/A

0DataRank · unranked

5 citations

Wenzhi Ji, Brendan G. Dwyer, Joey Lu, Jing Bian, Gianna M. Colombo +23 more

Rewiring the Fusion Oncoprotein EWSR1::FLI1 in Ewing Sarcoma with Bivalent Small Molecules

Journal of the American Chemical Society(2025)10.1021/jacs.5c05634

N/A

0DataRank · unranked

3 citations

Ryan P. Golden, Giulia DiGiovanni, Briana Howard, Roman C. Sarott, Basel A. Karim +8 more

Rational Design of CDK12/13 and BRD4 Molecular Glue Degraders

Angewandte Chemie(2025)10.1002/ange.202508427

N/A

0DataRank · unranked

0 citations

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