Stefan Knapp

Also affiliated with Structural Genomics Consortium

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 2%percentile

1.9Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification

International Journal of Molecular Sciences(2021)10.3390/ijms22020566

Top 11%

1.9DataRank

Top 11%110 citations

Hassan Al‐Ali, David Andrews, Christopher R. M. Asquith, Alison D. Axtman, Ivan Đikić +25 more

Papers

Driven by 49 papers — median percentile 89. Top paper: “The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification”.

The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification

International Journal of Molecular Sciences(2021)10.3390/ijms22020566

Top 11%

1.9DataRank

Top 11%110 citations

Hassan Al‐Ali, David Andrews, Christopher R. M. Asquith, Alison D. Axtman, Ivan Đikić +25 more

PFI-1, a Highly Selective Protein Interaction Inhibitor, Targeting BET Bromodomains

Cancer Research(2013)10.1158/0008-5472.can-12-3292

N/A

0.828DataRank · unranked

249 citations

David Da Costa, Angeliki Thanasopoulou, Panagis Filippakopoulos, Paul V. Fish, Martin Philpott +12 more

The C-terminal PHDVC5HCH tandem domain of NSD2 is a combinatorial reader of unmodified H3K4 and tri-methylated H3K27 that regulates transcription of cell adhesion genes in multiple myeloma

Nucleic Acids Research(2024)10.1093/nar/gkae1121

N/A

0.324DataRank · unranked

6 citations

Charlotte L Kaestner, Michela Ghitti, Giacomo Quilici, Paolo Cocomazzi, Jianping Li +6 more

A Chemical Probe for Dark Kinase STK17B Derives its Potency and High Selectivity Through a Unique P-loop Conformation

ChemRxiv(2020)10.26434/chemrxiv.12616178

N/A

0.165DataRank · unranked

2 citations

A. Chaikuad, Carrow I. Wells, Safal Shrestha, William J. Zuercher, Julie E. Pickett +10 more

Discovery of Potent Plasmodium falciparum Protein Kinase 6 (PfPK6) Inhibitors with a Type II Inhibitor Pharmacophore

ChemRxiv(2022)10.26434/chemrxiv-2022-6v14d

N/A

0.104DataRank · unranked

1 citations

Anna Truong, Frank E. Kwarcinski, Chandi de Silva, Krisha Avalani, Tammy M. Havener +10 more

Nucleotide binding, evolutionary insights and interaction partners of the pseudokinase Unc-51-like kinase 4

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.18.159293

N/A

0DataRank · unranked

2 citations

Deep Chatterjee, Sebastian Mathea, Safal Shrestha, Jonathan St‐Germain, Manipa Saha +5 more

Structure of LRRK2 in Parkinson’s disease and model for microtubule interaction

Nature(2020)10.1038/s41586-020-2673-2

N/A

0DataRank · unranked

247 citations

John Salogiannis, Sebastian Mathea, David Snead, Indrajit Lahiri, Mariusz Matyszewski +9 more

A Chemical Probe for Dark Kinase STK17B Derives its Potency and High Selectivity Through a Unique P-loop Conformation

ChemRxiv(2020)10.26434/chemrxiv.12616178.v1

N/A

0DataRank · unranked

1 citations

A. Chaikuad, Carrow I. Wells, Safal Shrestha, William J. Zuercher, Julie E. Pickett +10 more

Conformation and Dynamics of the Kinase Domain Drive Subcellular Location and Activation of LRRK2.

Research Square(2020)10.21203/rs.3.rs-59611/v1

N/A

0DataRank · unranked

0 citations

Jui‐Hung Weng, Phillip C. Aoto, Daniela Boassa, Steven Silletti, Sebastian Mathea +7 more

Copper is required for oncogenic BRAF signalling and tumorigenesis

UNC Libraries(2020)10.17615/hcaw-fj23

N/A

0DataRank · unranked

0 citations

Xiaojie Yao, Christopher M. Counter, Sharon L. Campbell, G. Aaron Hobbs, Dennis J. Thiele +6 more

Structural Determinants of G-protein α Subunit Selectivity by Regulator of G-protein Signaling 2 (RGS2)

UNC Libraries(2020)10.17615/fvc2-w539

N/A

0DataRank · unranked

0 citations

Brenda Temple, Stefan Knapp, A.K. Roos, Francis S. Willard, Bryan L. Roth +6 more

Development of a potent and selective chemical probe for the pleiotropic kinase CK2

Cell chemical biology(2021)10.1016/j.chembiol.2020.12.013

N/A

0DataRank · unranked

113 citations

David H. Drewry, Julie E. Pickett, Amelie Tjaden, Andreas Krämer, Susanne Müller +6 more

Nucleotide Binding, Evolutionary Insights, and Interaction Partners of the Pseudokinase Unc-51-like Kinase 4

Structure(2020)10.1016/j.str.2020.07.016

N/A

0DataRank · unranked

39 citations

Deep Chatterjee, Sebastian Mathea, Safal Shrestha, Jonathan St‐Germain, Manipa Saha +5 more

Conformation and dynamics of the kinase domain drive subcellular location and activation of LRRK2

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2100844118

N/A

0DataRank · unranked

77 citations

Jui‐Hung Weng, Phillip C. Aoto, Daniela Boassa, Sebastian Mathea, Steve Silletti +8 more

Mutation in Abl kinase with altered drug-binding kinetics indicates a novel mechanism of imatinib resistance

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2111451118

N/A

0DataRank · unranked

73 citations

Benedict‐Tilman Berger, Aziz M. Rangwala, YiTing Paung, Jessica Tom, Hannah Philipose +7 more

Large-Scale Recombinant Production of the SARS-CoV-2 Proteome for High-Throughput and Structural Biology Applications

Frontiers in Molecular Biosciences(2021)10.3389/fmolb.2021.653148

N/A

0DataRank · unranked

55 citations

Sophie Marianne Korn, Nusrat S. Qureshi, Marie Dujardin, Martí Ninot‐Pedrosa, Rupert Abele +95 more

Controlling the Covalent Reactivity of a Kinase Inhibitor with Light

Angewandte Chemie International Edition(2021)10.1002/anie.202103767

N/A

0DataRank · unranked

46 citations

A. Chaikuad, Benedict‐Tilman Berger, Katharina Bauer, Pierre Koch, Stefan Laufer +3 more

Design of a “Two-in-One” Mutant-Selective Epidermal Growth Factor Receptor Inhibitor That Spans the Orthosteric and Allosteric Sites

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.1c00848

N/A

0DataRank · unranked

43 citations

David E. Heppner, Ciric To, Marcel Günther, Bo Hee Shin, Jaimin K. Rana +13 more

Inhibitors of the Hippo Pathway Kinases STK3/MST2 and STK4/MST1 Have Utility for the Treatment of Acute Myeloid Leukemia

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.1c00804

N/A

0DataRank · unranked

34 citations

A. Chaikuad, Nicole A. Bakas, Allison S. Limpert, Lester J. Lambert, Douglas J. Sheffler +11 more

Controlling the Covalent Reactivity of a Kinase Inhibitor with Light

Angewandte Chemie(2021)10.1002/ange.202103767

N/A

0DataRank · unranked

4 citations

A. Chaikuad, Benedict‐Tilman Berger, Katharina Bauer, Pierre Koch, Stefan Laufer +3 more

Mutation in Abl kinase with altered drug binding kinetics indicates a novel mechanism of imatinib resistance

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.28.449968

N/A

0DataRank · unranked

4 citations

Benedict‐Tilman Berger, Aziz M. Rangwala, YiTing Paung, Jessica Tom, Hannah Philipose +7 more

Development of the First Covalent Monopolar Spindle Kinase 1 (MPS1/TTK) Inhibitor

ChemRxiv(2021)10.26434/chemrxiv.14601264.v1

N/A

0DataRank · unranked

2 citations

André da Silva Santiago, Caio dos Reis, Jéssica E. Takarada, Priscila Mezzomo, Katlin B. Massirer +9 more

Two helices control the dynamic crosstalk between the catalytic domains of LRRK2

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.29.462278

N/A

0DataRank · unranked

1 citations

Phillip C. Aoto, Robin Lorenz, Jian Wu, Sven H. Schmidt, Jascha T. Manschwetus +6 more

Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases

The FASEB Journal(2021)10.1096/fasebj.2021.35.s1.02446

N/A

0DataRank · unranked

0 citations

Sebastian Mathea, Hanna Karvonen, Ketan Malhotra, Deep Chatterjee, Wilhelmiina Niininen +10 more

Development of the First Covalent Monopolar Spindle Kinase 1 (MPS1/TTK) Inhibitor

ChemRxiv(2021)10.26434/chemrxiv.14601264

N/A

0DataRank · unranked

0 citations

André da Silva Santiago, Caio dos Reis, Jéssica E. Takarada, Priscila Mezzomo, Katlin B. Massirer +9 more

Macrocyclization of Quinazoline-Based EGFR Inhibitors Leads to Exclusive Mutant Selectivity for EGFR L858R and Del19

Journal of Medicinal Chemistry(2022)10.1021/acs.jmedchem.2c01041

N/A

0DataRank · unranked

31 citations

Tyler S. Beyett, William W. Feng, Andreas Krämer, Janik Weckesser, Ilse K. Schaeffner +6 more

LRRK2 dynamics analysis identifies allosteric control of the crosstalk between its catalytic domains

PLoS Biology(2022)10.1371/journal.pbio.3001427

N/A

0DataRank · unranked

27 citations

Phillip C. Aoto, Robin Lorenz, Jian Wu, Sven H. Schmidt, Jascha T. Manschwetus +8 more

Development of the First Covalent Monopolar Spindle Kinase 1 (MPS1/TTK) Inhibitor

Journal of Medicinal Chemistry(2022)10.1021/acs.jmedchem.1c01165

N/A

0DataRank · unranked

27 citations

André da Silva Santiago, Martin P. Schwalm, Zexi Hu, C.V. dos Reis, Jéssica E. Takarada +11 more

Calcium/calmodulin-dependent protein kinase kinase 2 regulates hepatic fuel metabolism

Molecular Metabolism(2022)10.1016/j.molmet.2022.101513

N/A

0DataRank · unranked

23 citations

Adam Dean, Andrea R. Ortiz, Pradip Saha, Nagireddy Putluri, Maricarmen D. Planas-Silva +11 more

Discovery of potent Plasmodium falciparum protein kinase 6 (PfPK6) inhibitors with a type II inhibitor pharmacophore

European Journal of Medicinal Chemistry(2022)10.1016/j.ejmech.2022.115043

N/A

0DataRank · unranked

17 citations

Anna Truong, Frank E. Kwarcinski, Chandi de Silva, Krisha Avalani, Tammy M. Havener +10 more

Kinase Domain Autophosphorylation Rewires the Activity and Substrate Specificity of CK1 Enzymes

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.0r463

N/A

0DataRank · unranked

1 citations

A. Chaikuad, Jun‐Song Chen, Jakob Gebel, Laura Tesmer, Rezart Zhubi +8 more

Resistance to kinase inhibition through shortened target engagement

Molecular & Cellular Oncology(2022)10.1080/23723556.2022.2029999

N/A

0DataRank · unranked

5 citations

Benedict‐Tilman Berger, Matthew B. Robers, Stefan Knapp, Markus A. Seeliger, Aziz M. Rangwala

SGC-CLK-1 (CAF-170) a chemical probe for the Cdc2-Like kinases CLK1, CLK2, and CLK4

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.12.15.520623

N/A

0DataRank · unranked

0 citations

Carrow I. Wells, Martin Schröder, Xiao Song, Carla Alamillo-Ferrer, Anshika Goenka +15 more

Inhibition of Parkinson’s disease–related LRRK2 by type I and type II kinase inhibitors: Activity and structures

Science Advances(2023)10.1126/sciadv.adk6191

N/A

0DataRank · unranked

48 citations

Amalia Villagran Suarez, Verena Dederer, Deep Chatterjee, Jaime Alegrio Louro, Stefan Knapp +3 more

Structure of LRRK1 and mechanisms of autoinhibition and activation

Nature Structural & Molecular Biology(2023)10.1038/s41594-023-01109-1

N/A

0DataRank · unranked

13 citations

Andrea M. Dickey, Yu Xuan Lin, Robert G. Abrisch, Sebastian Mathea, Deep Chatterjee +6 more

Death by a thousand cuts through kinase inhibitor combinations that maximize selectivity and enable rational multitargeting

eLife(2023)10.7554/elife.86189

N/A

0DataRank · unranked

10 citations

Sukrit Singh, Benedict‐Tilman Berger, Stefan Knapp, John D. Chodera, Markus A. Seeliger +1 more

SGC-CLK-1: A chemical probe for the Cdc2-like kinases CLK1, CLK2, and CLK4

Current Research in Chemical Biology(2023)10.1016/j.crchbi.2023.100045

N/A

0DataRank · unranked

4 citations

Carrow I. Wells, Martin Schröder, Xiao Song, Carla Alamillo‐Ferrer, Anshika Goenka +15 more

Death by a Thousand Cuts – Combining Kinase Inhibitors for Selective Target Inhibition and Rational Polypharmacology

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.13.523972

N/A

0DataRank · unranked

1 citations

Sukrit Singh, Benedict‐Tilman Berger, Stefan Knapp, John D. Chodera, Markus A. Seeliger +1 more

Novel dihydropteridinone derivatives as potent and selective inhibitors of the understudied human vaccinia-related kinase 1 (VRK1)

ChemRxiv(2023)10.26434/chemrxiv-2023-cmgsv

N/A

0DataRank · unranked

1 citations

Luiz Antônio Dutra, Michael Hawgood, C.V. dos Reis, Ricardo A. M. Serafim, Marcos Antonio Ferreira +21 more

Back-Pocket Optimization of 2-Aminopyrimidine-Based Macrocycles Leads to Potent EPHA2/GAK Kinase Inhibitors

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c00411

N/A

0DataRank · unranked

14 citations

Rezart Zhubi, Andreas Krämer, Marwah Karim, Do Hoang Nhu Tran, Andreas C. Joerger +12 more

The endocannabinoid anandamide mediates anti‐inflammatory effects through activation of NR4A nuclear receptors

British Journal of Pharmacology(2024)10.1111/bph.17366

N/A

0DataRank · unranked

11 citations

Beatrice Pflüger‐Müller, Virna Margarita Martín Giménez, Fiona Sailer, Henrik Dirks, Simonida Zehr +21 more

Modulating Androgen Receptor-Driven Transcription in Prostate Cancer with Selective CDK9 Inhibitors

Cell chemical biology(2020)10.1016/j.chembiol.2020.10.001

N/A

0DataRank · unranked

81 citations

Shelby K. Doyle, David B. Freeman, Christina Lee, Becky Leifer, Sajjeev Jagannathan +34 more

Type-II kinase inhibitors that target Parkinson’s Disease-associated LRRK2

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.17.613365

N/A

0DataRank · unranked

4 citations

Katherine J. Surridge, Marta Sanz Murillo, Verena Dederer, Andreas Krämer, Martin P. Schwalm +8 more

Back-pocket optimization of 2-aminopyrimidine-based macrocycles leads to potent dual EPHA2/GAK kinase inhibitors with antiviral activity

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.18.580805

N/A

0DataRank · unranked

1 citations

Rezart Zhubi, Andreas Kraemer, Marwah Karim, Do Hoang Nhu Tran, Andreas C. Joerger +12 more

Enantioselective protein affinity selection mass spectrometry (E-ASMS)

Nature Communications(2025)10.1038/s41467-025-67403-2

N/A

0DataRank · unranked

1 citations

Jianxian Sun, Shabbir Ahmad, Diwen Yang, Fengling Li, U Hang Chan +34 more

Enantioselective Protein Affinity Selection Mass Spectrometry (E-ASMS)

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.17.633682

N/A

0DataRank · unranked

7 citations

Jianxian Sun, Shabbir Ahmad, Diwen Yang, Fengling Li, U Hang Chan +33 more

Synthesis and Characterization of ULK1/2 Kinase Inhibitors that Inhibit Autophagy and Upregulate Expression of Major Histocompatibility Complex I for the Treatment of Non-Small Cell Lung Cancer

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.05.674519

N/A

0DataRank · unranked

2 citations

Huiyu Ren, Nicole A. Bakas, Dhanya Panickar, Lester J. Lambert, Maria Celeridad +16 more

A Chemical Probe for Dark Kinase STK17B Derives Its Potency and High Selectivity through a Unique P-Loop Conformation

Journal of Medicinal Chemistry(2020)10.1021/acs.jmedchem.0c01174

N/A

0DataRank · unranked

30 citations

A. Chaikuad, Carrow I. Wells, Safal Shrestha, William J. Zuercher, Julie E. Pickett +10 more

Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases

Molecular Cell(2020)10.1016/j.molcel.2020.06.018

N/A

0DataRank · unranked

104 citations

Sebastian Mathea, Hanna Karvonen, Ketan Malhotra, Deep Chatterjee, Wilhelmiina Niininen +10 more

Stefan Knapp

Indexed papers

Top data-sharing exemplar

Papers