Emad Tajkhorshid

Biochemistry, Genetics and Molecular BiologyMedicineNeuroscience

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 5%percentile

0.395Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

IHMCIF: An Extension of the PDBx/mmCIF Data Standard for Integrative Structure Determination Methods

Journal of Molecular Biology(2024)10.1016/j.jmb.2024.168546

Top 46%

0.395DataRank

Top 46%11 citations

Benjamin Webb, John Westbrook, Thomas D. Goddard, Christian A. Hanke, Andrea Graziadei +30 more

Papers

Driven by 115 papers — median percentile 54. Top paper: “Structural basis of complex formation between mitochondrial anion channel VDAC1 and Hexokinase-II”.

Structural basis of complex formation between mitochondrial anion channel VDAC1 and Hexokinase-II

Communications Biology(2021)10.1038/s42003-021-02205-y

N/A

1.7DataRank · unranked

61 citations

Po‐Chao Wen, Qunli Cheng, Meiying Yang, Gayathri K. Natarajan, Amadou K.S. Camara +3 more

Cryo-EM structures of a lipid-sensitive pentameric ligand-gated ion channel embedded in a phosphatidylcholine-only bilayer

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.1906823117

N/A

1.5DataRank · unranked

46 citations

Yuhang Wang, Zhening Zhang, Zhiyu Zhao, Gisela D. Cymes, Emad Tajkhorshid +2 more

Scalable molecular dynamics with NAMD

Journal of Computational Chemistry(2005)10.1002/jcc.20289

N/A

1.5DataRank · unranked

17273 citations

Rosemary Braun, Wei Wang, James Gumbart, Emad Tajkhorshid, Elizabeth Villa +8 more

PIP2-dependent coupling of voltage sensor and pore domains in Kv7.2 channel

Communications Biology(2021)10.1038/s42003-021-02729-3

N/A

0.889DataRank · unranked

26 citations

Jiaren Zhang, Eung Chang Kim, Kin Lam, Hee Jung Chung, Emad Tajkhorshid +1 more

Myr-Arf1 conformational flexibility at the membrane surface sheds light on the interactions with ArfGAP ASAP1

Nature Communications(2023)10.1038/s41467-023-43008-5

N/A

0.667DataRank · unranked

20 citations

Olivier Soubias, Shashank Pant, Frank Heinrich, Alexander Vogel, Jess Li +10 more

WSB1/2 target chromatin-bound lysine-methylated RelA for proteasomal degradation and NF-κB termination

Nucleic Acids Research(2024)10.1093/nar/gkae161

N/A

0.474DataRank · unranked

10 citations

Yuanyuan Yu, Xiuqun Zou, Yaning Du, Qiankun Liang, Mengyao Gong +12 more

IHMCIF: An Extension of the PDBx/mmCIF Data Standard for Integrative Structure Determination Methods

Journal of Molecular Biology(2024)10.1016/j.jmb.2024.168546

Top 46%

0.395DataRank

Top 46%11 citations

Benjamin Webb, John Westbrook, Thomas D. Goddard, Christian A. Hanke, Andrea Graziadei +30 more

A CLC-ec1 mutant reveals global conformational change and suggests a unifying mechanism for the CLC Cl–/H+ transport cycle

eLife(2020)10.7554/elife.53479

N/A

0DataRank · unranked

50 citations

Ricky C. Cheng, Tao Jiang, Irimpan I. Mathews, Richard A. Stein, Antoine Koehl +4 more

Parameterization of a drug molecule with a halogen σ-hole particle using ffTK: Implementation, testing, and comparison

The Journal of Chemical Physics(2020)10.1063/5.0022802

N/A

0DataRank · unranked

19 citations

Ànna Pavlova, Emad Tajkhorshid, James C. Gumbart, Yui Tik Pang

Conformational changes in the nucleotide‐binding domains of P‐glycoprotein induced by ATP hydrolysis

FEBS Letters(2020)10.1002/1873-3468.13992

N/A

0DataRank · unranked

18 citations

Karan Kapoor, Emad Tajkhorshid, Sepehr Dehghani‐Ghahnaviyeh

Membrane surface recognition by the ASAP1 PH domain and consequences for interactions with the small GTPase Arf1

Science Advances(2020)10.1126/sciadv.abd1882

N/A

0DataRank · unranked

39 citations

Shashank Pant, Frank Heinrich, Yue Zhang, Neeladri Sekhar Roy, Jess Li +7 more

Aquaporin-7: A Dynamic Aquaglyceroporin With Greater Water and Glycerol Permeability Than Its Bacterial Homolog GlpF

Frontiers in Physiology(2020)10.3389/fphys.2020.00728

N/A

0DataRank · unranked

36 citations

Paween Mahinthichaichan, David T. Lodowski, Thomas Kowatz, Emad Tajkhorshid, Andreas Engel +3 more

Twisting and tilting of a mechanosensitive molecular probe detects order in membranes

Chemical Science(2020)10.1039/d0sc02175j

N/A

0DataRank · unranked

33 citations

Karolína Straková, Stefan Matile, Emad Tajkhorshid, Giuseppe Licari

Hydrogen-deuterium exchange mass spectrometry captures distinct dynamics upon substrate and inhibitor binding to a transporter

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.03.023564

N/A

0DataRank · unranked

7 citations

Chloé Martens, Mrinal Shekhar, Shashank Pant, Grant A. Pellowe, Andy M. Lau +6 more

The Structures of Secretory and Dimeric Immunoglobulin A

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.02.16.951780

N/A

0DataRank · unranked

5 citations

Benjamin W. Parker, Andrey Malyutin, Nandan Haloi, Kathryn E. Huey‐Tubman, Emad Tajkhorshid +2 more

Structural Basis of Complex Formation Between Mitochondrial Anion Channel VDAC1 and Hexokinase-II

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.18.365965

N/A

0DataRank · unranked

5 citations

Po‐Chao Wen, Qunlii Cheng, Meiying Yang, Gayathri Natarajan, Amadou K.S. Camara +3 more

Glutamate transporters contain a conserved chloride channel with two hydrophobic gates

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.25.115360

N/A

0DataRank · unranked

4 citations

Shashank Pant, Qianyi Wu, Rosemary J. Cater, Meghna Sobti, Robert J. Vandenberg +5 more

How to build a water-splitting machine: structural insights into photosystem II assembly

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.14.294884

N/A

0DataRank · unranked

3 citations

Stefan Bohn, Sandra K. Schuller, Oliver Arnolds, Madeline Möller, Jakob Meier‐Credo +11 more

Anti-inflammatory dopamine- and serotonin-based endocannabinoid epoxides reciprocally regulate cannabinoid receptors and the TRPV1 channel

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.05.079624

N/A

0DataRank · unranked

0 citations

Lauren N. Carnevale, Zili Xie, Javier L. Baylon, Emad Tajkhorshid, Hongzhen Hu +2 more

Cation-π Interactions and their Functional Roles in Membrane Proteins

Journal of Molecular Biology(2021)10.1016/j.jmb.2021.167035

N/A

0DataRank · unranked

161 citations

Ali Rasouli, Grace D. Galles, Christophe Chipot, Emad Tajkhorshid, Christopher A. Ahern +1 more

CryoFold: Determining protein structures and data-guided ensembles from cryo-EM density maps

Matter(2021)10.1016/j.matt.2021.09.004

N/A

0DataRank · unranked

51 citations

Genki Terashi, Chitrak Gupta, Daipayan Sarkar, Gaspard Debussche, Nicholas J. Sisco +11 more

Binding mode of SARS-CoV-2 fusion peptide to human cellular membrane

Biophysical Journal(2021)10.1016/j.bpj.2021.02.041

N/A

0DataRank · unranked

48 citations

Muyun Lihan, Karan Kapoor, Emad Tajkhorshid, Defne Gorgun

Anti-inflammatory dopamine- and serotonin-based endocannabinoid epoxides reciprocally regulate cannabinoid receptors and the TRPV1 channel

Nature Communications(2021)10.1038/s41467-021-20946-6

N/A

0DataRank · unranked

34 citations

Lauren N. Carnevale, Zili Xie, Javier L. Baylon, Emad Tajkhorshid, Hongzhen Hu +2 more

Active participation of membrane lipids in inhibition of multidrug transporter P-glycoprotein

Chemical Science(2021)10.1039/d0sc06288j

N/A

0DataRank · unranked

30 citations

Shashank Pant, Emad Tajkhorshid, Karan Kapoor

Molecular mechanism of capsid disassembly in hepatitis B virus

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2102530118

N/A

0DataRank · unranked

30 citations

Martin Gruebele, Emad Tajkhorshid, Zhaleh Ghaemi

Rationalizing the generation of broad spectrum antibiotics with the addition of a positive charge

Chemical Science(2021)10.1039/d1sc04445a

N/A

0DataRank · unranked

30 citations

Archit Vasan, Emily J. Geddes, Arjun Prasanna, Po‐Chao Wen, William W. Metcalf +3 more

Defining the Energetic Basis for a Conformational Switch Mediating Ligand-Independent Activation of Mutant Estrogen Receptors in Breast Cancer

Molecular Cancer Research(2021)10.1158/1541-7786.mcr-20-1017

N/A

0DataRank · unranked

13 citations

Weiyi Toy, Kathryn E. Carlson, Trusha Bhatt, Sean W. Fanning, Geoffrey L. Greene +5 more

Calmodulin complexes with brain and muscle creatine kinase peptides

Current Research in Structural Biology(2021)10.1016/j.crstbi.2021.05.001

N/A

0DataRank · unranked

6 citations

Anda Trifan, Neal Patel, Ashley Vanderbeck, J. Bredfelt, Emad Tajkhorshid +5 more

Intelligent Resolution: Integrating Cryo-EM with AI-driven Multi-resolution Simulations to Observe the SARS-CoV-2 Replication-Transcription Machinery in Action

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.09.463779

N/A

0DataRank · unranked

6 citations

Defne Gorgun, Zongyi Li, Alexander Brace, Maxim Zvyagin, Heng Ma +29 more

Investigation of gating in outer membrane porins provides new perspectives on antibiotic resistance mechanisms

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.09.459668

N/A

0DataRank · unranked

4 citations

Nandan Haloi, Rebecca J. Ulrich, Mary Elizabeth Metcalf, Po‐Chao Wen, William W. Metcalf +4 more

Extended-Ensemble Docking to Probe Evolution of Ligand Binding Sites During Large-Scale Structural Changes of Proteins

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.28.437371

N/A

0DataRank · unranked

3 citations

Sundar Thangapandian, Emad Tajkhorshid, Karan Kapoor

Ataxia-linked SLC1A3 mutations alter EAAT1 chloride channel activity and glial regulation of CNS function

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.05.463128

N/A

0DataRank · unranked

3 citations

Azman Akhter, Shashank Pant, Eunjoo Cho, Jin Xin Zhu, Alastair Garner +5 more

Molecular Mechanism of Capsid Disassembly in Hepatitis B Virus

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.08.430262

N/A

0DataRank · unranked

2 citations

Martin Gruebele, Emad Tajkhorshid, Zhaleh Ghaemi

Editorial: Mitochondrial Exchangers and Transporters in Cell Survival and Death

Frontiers in Physiology(2021)10.3389/fphys.2021.745353

N/A

0DataRank · unranked

2 citations

Emad Tajkhorshid, Amadou K.S. Camara, Wai-Meng Kwok

Amphiphilic Distyrylbenzene Derivatives as Potential Therapeutic and Imaging Agents for the Soluble Amyloid-β Oligomers in Alzheimer’s Disease

ChemRxiv(2021)10.26434/chemrxiv.13605998

N/A

0DataRank · unranked

2 citations

Hong‐Jun Cho, Soumyo Sen, Andres S. Arango, Truc T. Huynh, Yong Huang +5 more

Structural transitions permitting ligand entry and exit in bacterial fatty acid binding proteins

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.16.460654

N/A

0DataRank · unranked

1 citations

M.G. Cuypers, Christy R. Grace, Shashank Pant, Chitra Subramanian, Emad Tajkhorshid +3 more

Amphiphilic Distyrylbenzene Derivatives as Potential Therapeutic and Imaging Agents for the Soluble Amyloid-β Oligomers in Alzheimer’s Disease

ChemRxiv(2021)10.26434/chemrxiv.13605998.v1

N/A

0DataRank · unranked

0 citations

Hong‐Jun Cho, Soumyo Sen, Andres S. Arango, Truc T. Huynh, Yong Huang +5 more

PIP 2 -dependent coupling of voltage sensor and pore domains in K v 7.2

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.11.443644

N/A

0DataRank · unranked

0 citations

Jiaren Zhang, Eung Chang Kim, Kin Lam, Hee Jung Chung, Emad Tajkhorshid +1 more

Rationalizing generation of broad spectrum antibiotics with the addition of a primary amine

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.10.455597

N/A

0DataRank · unranked

0 citations

Archit Vasan, Emily J. Geddes, Arjun Prasanna, Po‐Chao Wen, William W. Metcalf +3 more

Role of internal loop dynamics in antibiotic permeability of outer membrane porins

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2117009119

N/A

0DataRank · unranked

43 citations

Nandan Haloi, Rebecca J. Ulrich, Mary Elizabeth Metcalf, Po‐Chao Wen, William W. Metcalf +4 more

Differential dynamics and direct interaction of bound ligands with lipids in multidrug transporter ABCG2

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2213437120

N/A

0DataRank · unranked

42 citations

Qin Yu, Sepehr Dehghani‐Ghahnaviyeh, Po‐Chao Wen, Julia Kowal, Kaspar P. Locher +2 more

Phthalate monoesters act through peroxisome proliferator-activated receptors in the mouse ovary

Reproductive Toxicology(2022)10.1016/j.reprotox.2022.04.002

N/A

0DataRank · unranked

39 citations

Kathy M. De La Torre, Andres S. Arango, Andressa Gonsioroski, Ashley Deviney, Alison M. Neff +5 more

Backbone amides are determinants of Cl− selectivity in CLC ion channels

Nature Communications(2022)10.1038/s41467-022-35279-1

N/A

0DataRank · unranked

26 citations

Kin Lam, Sepehr Dehghani‐Ghahnaviyeh, Eva Fortea, Jason D. Galpin, Christopher A. Ahern +3 more

Posttranslational modifications optimize the ability of SARS-CoV-2 spike for effective interaction with host cell receptors

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2119761119

N/A

0DataRank · unranked

34 citations

Tianle Chen, Emad Tajkhorshid, Karan Kapoor

Extended-ensemble docking to probe dynamic variation of ligand binding sites during large-scale structural changes of proteins

Chemical Science(2022)10.1039/d2sc00841f

N/A

0DataRank · unranked

28 citations

Sundar Thangapandian, Emad Tajkhorshid, Karan Kapoor

Proton-driven alternating access in a spinster lipid transporter

Nature Communications(2022)10.1038/s41467-022-32759-2

N/A

0DataRank · unranked

28 citations

Ali Rasouli, Sepehr Dehghani‐Ghahnaviyeh, Samantha Gies, Emad Tajkhorshid, Reza Dastvan

Targeting lipid–protein interaction to treat Syk-mediated acute myeloid leukemia

Nature Chemical Biology(2022)10.1038/s41589-022-01150-z

N/A

0DataRank · unranked

27 citations

Ashutosh Sharma, Shashank Pant, Muyun Lihan, Mi-Jeong Park, Melissa R. Pergande +10 more

Cryo‐EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms

The EMBO Journal(2022)10.15252/embj.2022111065

N/A

0DataRank · unranked

25 citations

James R. Thompson, Sepehr Dehghani‐Ghahnaviyeh, Shashank Pant, Phuoc Xuan Dang, Jarrod B. French +4 more

Ataxia-linked SLC1A3 mutations alter EAAT1 chloride channel activity and glial regulation of CNS function

Journal of Clinical Investigation(2022)10.1172/jci154891

N/A

0DataRank · unranked

24 citations

Azman Akhter, Shashank Pant, Eunjoo Cho, Jin Xin Zhu, Alastair Garner +5 more

Lipid-mediated prestin organization in outer hair cell membranes and its implications in sound amplification

Nature Communications(2022)10.1038/s41467-022-34596-9

N/A

0DataRank · unranked

19 citations

Zhiyu Zhao, Emad Tajkhorshid, Sepehr Dehghani‐Ghahnaviyeh

Identification of structural transitions in bacterial fatty acid binding proteins that permit ligand entry and exit at membranes

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.101676

N/A

0DataRank · unranked

13 citations

M.G. Cuypers, Christy R. Grace, Shashank Pant, Chitra Subramanian, Emad Tajkhorshid +3 more

Anthracycline derivatives inhibit cardiac CYP2J2

Journal of Inorganic Biochemistry(2022)10.1016/j.jinorgbio.2022.111722

N/A

0DataRank · unranked

9 citations

Andres S. Arango, Swapnil Shah, William R. Arnold, Emad Tajkhorshid, Aditi Das +1 more

Intelligent resolution: Integrating Cryo-EM with AI-driven multi-resolution simulations to observe the severe acute respiratory syndrome coronavirus-2 replication-transcription machinery in action

The International Journal of High Performance Computing Applications(2022)10.1177/10943420221113513

N/A

0DataRank · unranked

6 citations

Defne Gorgun, Michael Salim, Zongyi Li, Alexander Brace, Maxim Zvyagin +29 more

Elevator mechanism dynamics in a sodium-coupled dicarboxylate transporter

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.01.490196

N/A

0DataRank · unranked

14 citations

Maria Lopez-Redondo, Christopher Mulligan, David B. Sauer, Jennifer J. Marden, Jinmei Song +7 more

Experiences Porting NAMD to the Data Parallel C++ Programming Model

International Workshop on OpenCL(2022)10.1145/3529538.3529560

N/A

0DataRank · unranked

8 citations

Jaemin Choi, Wei Jiang, Emad Tajkhorshid, David J. Hardy

Structures and membrane interactions of native serotonin transporter in complexes with psychostimulants

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.03.506477

N/A

0DataRank · unranked

3 citations

Zhiyu Zhao, Emad Tajkhorshid, Eric Gouaux, Dongxue Yang

Proton-driven alternating access in a spinster transporter, an emerging family of broad-specificity efflux pumps

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.03.482761

N/A

0DataRank · unranked

0 citations

Ali Rasouli, Sepehr Dehghani‐Ghahnaviyeh, Samantha Gies, Emad Tajkhorshid, Reza Dastvan

Proton-driven alternating access in a spinster transporter, an emerging family of broad-specificity efflux pumps

Research Square(2022)10.21203/rs.3.rs-1475419/v1

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0DataRank · unranked

0 citations

Ali Rasouli, Sepehr Dehghani‐Ghahnaviyeh, Samantha Gies, Emad Tajkhorshid, Reza Dastvan

Tuning aromatic contributions by site-specific encoding of fluorinated phenylalanine residues in bacterial and mammalian cells

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.04.12.488046

N/A

0DataRank · unranked

0 citations

Daniel T. Infield, Colin J. Clark, Marcus L. Hemshorn, Shivani Manikandan, Frederico Sassoli Fazan +7 more

A Spatial Whole-Cell Model for Hepatitis B Viral Infection and Drug Interactions

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.01.494377

N/A

0DataRank · unranked

0 citations

Oluwadara Nafiu, Emad Tajkhorshid, Martin Gruebele, Jianming Hu, Zhaleh Ghaemi

Lipid-mediated organization of prestin in the outer hair cell membrane and its implications in sound amplification

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.30.494028

N/A

0DataRank · unranked

0 citations

Zhiyu Zhao, Emad Tajkhorshid, Sepehr Dehghani‐Ghahnaviyeh

Backbone amides are key determinants of Cl − selectivity in CLC ion channels

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.01.498497

N/A

0DataRank · unranked

0 citations

Kin Lam, Sepehr Dehghani‐Ghahnaviyeh, Eva Fortea, Jason D. Galpin, Christopher A. Ahern +3 more

Backbone amides are key determinants of Cl− selectivity in CLC ion channels

Research Square(2022)10.21203/rs.3.rs-1813428/v1

N/A

0DataRank · unranked

0 citations

Kin Lam, Sepehr Dehghani‐Ghahnaviyeh, Eva Fortea, Jason D. Galpin, Christopher A. Ahern +3 more

VMD as a Platform for Interactive Small Molecule Preparation and Visualization in Quantum and Classical Simulations

Journal of Chemical Information and Modeling(2023)10.1021/acs.jcim.3c00658

N/A

0DataRank · unranked

98 citations

John E. Stone, João V. Ribeiro, Jan Saam, Lydia Freddolino, Rafael C. Bernardi +2 more

Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter

Nature Communications(2023)10.1038/s41467-023-42937-5

N/A

0DataRank · unranked

31 citations

Matt Sinclair, Hale S. Hasdemir, Richard A. Stein, Erkan Karakaş, Emad Tajkhorshid +2 more

A Rigorous Framework for Calculating Protein–Protein Binding Affinities in Membranes

Journal of Chemical Theory and Computation(2023)10.1021/acs.jctc.3c00941

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0DataRank · unranked

21 citations

James C. Gumbart, Haochuan Chen, Emad Tajkhorshid, Benoı̂t Roux, Christophe Chipot +1 more

Tuning phenylalanine fluorination to assess aromatic contributions to protein function and stability in cells

Nature Communications(2023)10.1038/s41467-022-35761-w

N/A

0DataRank · unranked

31 citations

Daniel T. Infield, Colin J. Clark, Marcus L. Hemshorn, Shivani Manikandan, Frederico Sassoli Fazan +7 more

Structures and membrane interactions of native serotonin transporter in complexes with psychostimulants

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2304602120

N/A

0DataRank · unranked

21 citations

Zhiyu Zhao, Emad Tajkhorshid, Eric Gouaux, Dongxue Yang

Insights into substrate transport and water permeation in the mycobacterial transporter MmpL3

Biophysical Journal(2023)10.1016/j.bpj.2023.03.018

N/A

0DataRank · unranked

14 citations

Atanu Acharya, Lixinhao Yang, Jinchan Liu, Emad Tajkhorshid, Helen I. Zgurskaya +3 more

A computational spatial whole-Cell model for hepatitis B viral infection and drug interactions

Scientific Reports(2023)10.1038/s41598-023-45998-0

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0DataRank · unranked

5 citations

Oluwadara Nafiu, Emad Tajkhorshid, Martin Gruebele, Jianming Hu, Zhaleh Ghaemi

Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.09.523303

N/A

0DataRank · unranked

9 citations

Alexander M. Barclay, Collin G. Borcik, Katherine Basore, Isabelle R. Gordon, Jialu Liu +15 more

Structure Reveals Homology in Elevator Transporters

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.14.544989

N/A

0DataRank · unranked

4 citations

Emad Tajkhorshid, Noah Trebesch

Molecular mechanisms of catalytic inhibition for active site mutations in glucose-6-phosphatase catalytic subunit 1 linked to glycogen storage disease

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.13.532485

N/A

0DataRank · unranked

1 citations

Richard A. Stein, Jonathan H. Sheehan, Emily M. Hawes, Richard M. O’Brien, Emad Tajkhorshid +2 more

Machine learning guided sampling of protein transition pathways

Biophysical Journal(2023)10.1016/j.bpj.2022.11.1605

N/A

0DataRank · unranked

0 citations

Emad Tajkhorshid, Hyun Park

Topological Learning Approach to Characterizing Biological Membranes

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.28.569053

N/A

0DataRank · unranked

0 citations

Hyun Park, Emad Tajkhorshid, Andres S. Arango

A Gram-negative-selective antibiotic that spares the gut microbiome

Nature(2024)10.1038/s41586-024-07502-0

N/A

0DataRank · unranked

130 citations

Rebecca J. Ulrich, Archit Vasan, Matt Sinclair, Po‐Chao Wen, Jessica R. Holmes +7 more

Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue

Nature Communications(2024)10.1038/s41467-024-46832-5

N/A

0DataRank · unranked

72 citations

Alexander M. Barclay, Collin G. Borcik, Katherine Basore, Deborah A. Berthold, Isabelle R. Gordon +18 more

Structure of the human dopamine transporter and mechanisms of inhibition

Nature(2024)10.1038/s41586-024-07739-9

N/A

0DataRank · unranked

55 citations

Vikas Navratna, Dilip K. Tosh, Audrey Chinn, Md Fulbabu Sk, Emad Tajkhorshid +3 more

GOLEM: Automated and Robust Cryo-EM-Guided Ligand Docking with Explicit Water Molecules

Journal of Chemical Information and Modeling(2024)10.1021/acs.jcim.4c00917

N/A

0DataRank · unranked

8 citations

Emad Tajkhorshid, Zhiyu Zhao

Improved Highly Mobile Membrane Mimetic Model for Investigating Protein–Cholesterol Interactions

Journal of Chemical Information and Modeling(2024)10.1021/acs.jcim.4c00619

N/A

0DataRank · unranked

7 citations

Emad Tajkhorshid, Muyun Lihan

Atomistic characterization of β2-glycoprotein I domain V interaction with anionic membranes

Journal of Thrombosis and Haemostasis(2024)10.1016/j.jtha.2024.07.010

N/A

0DataRank · unranked

6 citations

Nicola Pozzi, Emad Tajkhorshid, Hale S. Hasdemir

The carboxy terminus causes interfacial assembly of oleate hydratase on a membrane bilayer

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.105627

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9 citations

Christy R. Grace, Hale S. Hasdemir, Yupeng Li, Carlos C. Rodríguez, Patrick Fernandes Rodrigues +8 more

Tumor-acquired somatic mutation affects conformation to abolish ABCG2-mediated drug resistance

Drug Resistance Updates(2024)10.1016/j.drup.2024.101066

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8 citations

Ali Rasouli, Sepehr Dehghani‐Ghahnaviyeh, Po‐Chao Wen, Yao Wang, J.A. Lynch +6 more

Membrane-bound model of the ternary complex between factor VIIa/tissue factor and factor X

Blood Advances(2024)10.1182/bloodadvances.2024014845

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6 citations

Alex Mortenson, Josepha-Clara Sedzro, Po‐Chao Wen, James H. Morrissey, Emad Tajkhorshid +1 more

Topological Learning Approach to Characterizing Biological Membranes

Journal of Chemical Information and Modeling(2024)10.1021/acs.jcim.4c00552

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4 citations

Hyun Park, Emad Tajkhorshid, Andres S. Arango

Broadening access to small-molecule parameterization with the force field toolkit

The Journal of Chemical Physics(2024)10.1063/5.0196848

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4 citations

Ànna Pavlova, P. Nelson, Zachary L. Glick, Lan Yang, Yui Tik Pang +6 more

Integrative analysis of pathogenic variants in glucose-6-phosphatase based on an AlphaFold2 model

PNAS Nexus(2024)10.1093/pnasnexus/pgae036

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7 citations

Richard A. Stein, Jonathan H. Sheehan, Emily M. Hawes, Richard M. O’Brien, Emad Tajkhorshid +2 more

Generating Concentration Gradients across Membranes for Molecular Dynamics Simulations of Periodic Systems

International Journal of Molecular Sciences(2024)10.3390/ijms25073616

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5 citations

Emad Tajkhorshid, Eric Shinn

Modeling Diffusive Motion of Ferredoxin and Plastocyanin on the PSI Domain of Procholorococcus marinus MIT9313

The Journal of Physical Chemistry B(2024)10.1021/acs.jpcb.4c05001

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3 citations

Emad Tajkhorshid, Zaida Luthey‐Schulten, Melih Şener, Aaron Chan

The Role of Protein–Lipid Interactions in Priming the Bacterial Translocon

Membranes(2024)10.3390/membranes14120249

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1 citations

Emad Tajkhorshid, Matt Sinclair

Single-molecule imaging reveals the roles of the membrane-binding motif and the C-terminal domain of RNase E in its localization and diffusion in Escherichia coli

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.11.05.622141

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5 citations

Yu-Huan Wang, Shobhna Shobhna, Seunghyeon Kim, Brooke Ramsey, Jeechul Woo +3 more

Voltage Sensor Conformations Induced by LQTS-associated Mutations in hERG Potassium Channels

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.05.17.594747

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1 citations

Co D. Quach, Lucas J. Handlin, Erin N. Lessie, Emad Tajkhorshid, Gucan Dai +1 more

Atomistic Characterization of Beta-2-Glycoprotein I Domain V Interaction with Anionic Membranes

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.19.585743

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0DataRank · unranked

0 citations

Nicola Pozzi, Emad Tajkhorshid, Hale S. Hasdemir

Cholesterol-targeting Wnt–β-catenin signaling inhibitors for colorectal cancer

Nature Chemical Biology(2025)10.1038/s41589-025-01870-y

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17 citations

Julian Zalejski, Shruti V. Bendre, Simona Kavrokova, Hale S. Hasdemir, Defne G. Ozgulbas +20 more

Molecular dynamics simulations of biological membranes and membrane-associated phenomena across scales

Current Opinion in Structural Biology(2025)10.1016/j.sbi.2025.103071

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11 citations

Hale S. Hasdemir, Tianle Chen, Po‐Chao Wen, Emad Tajkhorshid, Noah Trebesch

Conformational free energy landscape of a glutamate transporter and microscopic details of its transport mechanism

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2416381122

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7 citations

Ashkan Fakharzadeh, Mahmoud Moradi, Emad Tajkhorshid, Sundar Thangapandian

Dissecting Large-Scale Structural Transitions in Membrane Transporters Using Advanced Simulation Technologies

The Journal of Physical Chemistry B(2025)10.1021/acs.jpcb.5c00104

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6 citations

Sepehr Dehghani‐Ghahnaviyeh, Noah Trebesch, Ali Rasouli, Tianle Chen, Karan Kapoor +3 more

Distinct Interactions of Cannabinol and Its Cytochrome P450-Generated Metabolites with Receptors and Sensory Neurons

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.5c00938

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6 citations

Luca Franchini, Hale S. Hasdemir, Elliot Lloyd, Jonathan Maturano, Katalin Rábl +8 more

Voltage sensor conformations induced by LQTS-associated mutations in hERG potassium channels

Nature Communications(2025)10.1038/s41467-025-62472-9

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4 citations

Co D. Quach, Lucas J. Handlin, Erin N. Lessie, Emad Tajkhorshid, Gucan Dai +1 more

Cryo-EM structure of the tissue factor/factor VIIa complex with a factor X mimetic reveals a novel allosteric mechanism

Blood(2025)10.1182/blood.2025029430

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4 citations

Amanda Photenhauer, Fabienne Birkle, Katarina Meze, Alex Mortenson, Cade Duckworth +7 more

Drug-bound outward-facing conformation of a heterodimeric ABC exporter suggests a putative mechanism of drug translocation

Nature Communications(2025)10.1038/s41467-025-65318-6

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4 citations

Matt Sinclair, Paola Bisignano, Yunsen Zhang, Emad Tajkhorshid, Hassane S. Mchaourab +1 more

Regulation of Rho guanine nucleotide exchange factor 3 by phosphorylation in the PH domain

iScience(2025)10.1016/j.isci.2025.112753

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3 citations

Jae‐Sung You, Carlos C. Rodríguez, Shashank Pant, Adriana Reyes‐Ordoñez, R.B. Abdullah +5 more

Probing the role of membrane in neutralizing activity of antibodies against influenza virus

Structure(2025)10.1016/j.str.2025.11.016

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1 citations

Timothy J.C. Tan, Po‐Chao Wen, Qi Wen Teo, Huibin Lv, Zhaleh Ghaemi +4 more

Restricted Surface Diffusion of Cytochromes on Bioenergetic Membranes with Anionic Lipids

Membranes(2025)10.3390/membranes15040124

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1 citations

Emad Tajkhorshid, Aaron Chan

Cholesterol efflux protein, ABCA1, supports anti-cancer functions of myeloid immune cells

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.02.19.638515

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2 citations

Yu Wang, Basel Hajyousif, Rajendra KC, Shounak Bhogale, Dhanya Pradeep +23 more

Single-molecule imaging reveals the role of membrane-binding motif and C-terminal domain of RNase E in its localization and diffusion in Escherichia coli

eLife(2025)10.7554/elife.105062.1

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0DataRank · unranked

1 citations

Yu-Huan Wang, Shobhna Shobhna, Seunghyeon Kim, Jeechul Woo, Emad Tajkhorshid +2 more

Roles of the membrane-binding motif and the C-terminal domain of RNase E in localization and diffusion in E. coli

eLife(2025)10.7554/elife.105062

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0DataRank · unranked

0 citations

Yu-Huan Wang, Shobhna Shobhna, Seunghyeon Kim, Brooke Ramsey, Jeechul Woo +3 more

Impact of anionic lipids on the energy landscape of conformational transition in anion exchanger 1 (AE1)

Nature Communications(2025)10.1038/s41467-025-66786-6

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0DataRank · unranked

0 citations

Francesca Vallese, Eva Gil‐Iturbe, Kookjoo Kim, Tito Calí, Matthias Quick +3 more

Impact of Lipid Composition on Membrane Partitioning and Permeability of Gas Molecules

Preprints.org(2025)10.20944/preprints202512.0429.v1

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0 citations

Ahmad R. Najafi, Fraser J. Moss, Ardeschir Vahedi‐Faridi, Walter F. Boron, Emad Tajkhorshid +1 more

Aβ(1-42) tetramer and octamer structures reveal edge conductivity pores as a mechanism for membrane damage

Nature Communications(2020)10.1038/s41467-020-16566-1

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251 citations

Eduard Puig, Thomas Botzanowski, Moeen Meigooni, Andres S. Arango, Jimmy Do +10 more

Hydrogen-deuterium exchange mass spectrometry captures distinct dynamics upon substrate and inhibitor binding to a transporter

Nature Communications(2020)10.1038/s41467-020-20032-3

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83 citations

Chloé Martens, Mrinal Shekhar, Shashank Pant, Grant A. Pellowe, Andy M. Lau +6 more

Structural basis for the reaction cycle of DASS dicarboxylate transporters

eLife(2020)10.7554/elife.61350

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73 citations

Noah Trebesch, Jennifer J. Marden, Nicolette Cocco, Jinmei Song, Akiko Koide +4 more

Membrane Interactions of Cy3 and Cy5 Fluorophores and Their Effects on Membrane-Protein Dynamics

Biophysical Journal(2020)10.1016/j.bpj.2020.05.027

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28 citations

Emad Tajkhorshid, Kin Lam

Identifying mutation hotspots reveals pathogenetic mechanisms of KCNQ2 epileptic encephalopathy

Scientific Reports(2020)10.1038/s41598-020-61697-6

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0DataRank · unranked

65 citations

Eung Chang Kim, Congcong Chen, Erik Procko, Shashank Pant, Kin Lam +8 more

Aberrant Expression of a Non-muscle RBFOX2 Isoform Triggers Cardiac Conduction Defects in Myotonic Dystrophy

Developmental Cell(2020)10.1016/j.devcel.2020.01.037

N/A

0DataRank · unranked

51 citations

Sushant Bangru, Feikai Lin, Kin Lam, Sara N. Koenig, Ellen R. Lubbers +9 more

Emad Tajkhorshid

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