Fen‐Biao Gao

University of Massachusetts Chan Medical School

Also affiliated with UMass Memorial Medical Center

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 35 papers. Top paper: “Poly(GR) and poly(GA) in cerebrospinal fluid as potential biomarkers for C9ORF72-ALS/FTD”.

Poly(GR) and poly(GA) in cerebrospinal fluid as potential biomarkers for C9ORF72-ALS/FTD

Nature Communications(2022)10.1038/s41467-022-30387-4

N/A

1.1DataRank · unranked

54 citations

Denitza Raitcheva, Daniel A. Bartlett, Mercedes Prudencio, Diane McKenna‐Yasek, Catherine Douthwright +12 more

p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR)

Cell(2021)10.1016/j.cell.2020.12.025

N/A

0.774DataRank · unranked

173 citations

Zohar Shipony, Rodrigo Lopez-Gonzalez, Lisa Nakayama, Yong‐Jie Zhang, Julien Couthouis +22 more

Ribosome inhibition by C9ORF72 -ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.30.274597

N/A

0.208DataRank · unranked

3 citations

E. Svidritskiy, Denis Susorov, Soojin Lee, Alexander Park, Gabriel Demo +3 more

Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency

Molecular Neurodegeneration(2020)10.1186/s13024-020-00369-5

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0DataRank · unranked

33 citations

Alireza Baradaran‐Heravi, Aruna D. Balgi, Xiujuan Wu, Tyler D. Yan, Steve Arns +12 more

Cellular and molecular phenotypes of C9orf72 ALS/FTD patient derived iPSC-microglia mono-cultures

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.03.277459

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0DataRank · unranked

6 citations

Eric Alsop, Jennifer Lévy, Lauren M. Gittings, Deepti Lall, Benjamin E. Rabichow +27 more

A C. elegans model of C9orf72-associated ALS/FTD uncovers a conserved role for eIF2D in RAN translation

Nature Communications(2021)10.1038/s41467-021-26303-x

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0DataRank · unranked

49 citations

Jihad Aburas, Gopinath Krishnan, Andrew C. Fleming, Ghanashyam D. Ghadge, Priota Islam +10 more

Ribosome profiling reveals novel regulation of C9ORF72 GGGGCC repeat-containing RNA translation

RNA(2021)10.1261/rna.078963.121

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0DataRank · unranked

29 citations

Emily E. Stackpole, Sandra Almeida, Olga Katsara, Botao Liu, Kuang Shen +4 more

Translation of the poly(GR) frame in C9ORF72-ALS/FTD is regulated by cis-elements involved in alternative splicing

Neurobiology of Aging(2021)10.1016/j.neurobiolaging.2021.04.030

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0DataRank · unranked

16 citations

Sandra Almeida, Fen‐Biao Gao, Alexa A. Lampasona

TBK1 haploinsufficiency in ALS and FTD compromises membrane trafficking

Acta Neuropathologica(2021)10.1007/s00401-021-02331-1

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0DataRank · unranked

16 citations

Sandra Almeida, Fen‐Biao Gao, Yubing Lu

The Coiled-Coil Protein Shrub Controls Neuronal Morphogenesis in Drosophila

UNC Libraries(2021)10.17615/96sb-hg66

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0DataRank · unranked

0 citations

Neal Sweeney, Jay E. Brenman, Fen‐Biao Gao, Yuh Nung Jan

Excessive release of inorganic polyphosphate by ALS/FTD astrocytes causes non-cell-autonomous toxicity to motoneurons

Neuron(2022)10.1016/j.neuron.2022.02.010

N/A

0DataRank · unranked

88 citations

Carolina Cefaliello, Agnieszka Dyrda, Nur Jury, Pablo Martínez, Iván Darío Parrado Díaz +32 more

Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM

Nature Communications(2022)10.1038/s41467-022-30418-0

N/A

0DataRank · unranked

79 citations

E. Svidritskiy, Denis Susorov, Soojin Lee, Alexander Park, Sarah N. Zvornicanin +4 more

RNA targets of TDP-43: Which one is more important in neurodegeneration?

Translational Neurodegeneration(2022)10.1186/s40035-021-00268-9

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0DataRank · unranked

6 citations

Fen‐Biao Gao, Dilara O. Halim

The enhanced association between mutant CHMP2B and spastin is a novel pathological link between frontotemporal dementia and hereditary spastic paraplegias

Acta Neuropathologica Communications(2022)10.1186/s40478-022-01476-8

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0DataRank · unranked

4 citations

Gopinath Krishnan, Sepideh Parsi, M. Pons�, Veroniki Nikolaki, Lu Cao +3 more

Translation of dipeptide repeat proteins in C9ORF72 -ALS/FTD through unique and redundant AUG initiation codons

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.06.503063

N/A

0DataRank · unranked

1 citations

Soojin Lee, Gopinath Krishnan, Yuanzheng Gu, Deborah Y. Kwon, Fen‐Biao Gao +3 more

PIKFYVE inhibition mitigates disease in models of diverse forms of ALS

Cell(2023)10.1016/j.cell.2023.01.005

N/A

0DataRank · unranked

100 citations

Gabriel Linares, Wen-Hsuan Chang, Yunsun Eoh, Gopinath Krishnan, Stacee Mendonca +23 more

Roadmap for C9ORF72 in Frontotemporal Dementia and Amyotrophic Lateral Sclerosis: Report on the C9ORF72 FTD/ALS Summit

Neurology and Therapy(2023)10.1007/s40120-023-00548-8

N/A

0DataRank · unranked

34 citations

Bryan J. Traynor, Janice Robertson, Ludo Van Den Bosch, Sami J. Barmada, Clive N. Svendsen +49 more

Dorsomedial prefrontal hypoexcitability underlies lost empathy in frontotemporal dementia

Neuron(2023)10.1016/j.neuron.2022.12.027

N/A

0DataRank · unranked

30 citations

Huihui Dai, So Yoen Choi, Karen Jansen‐West, Alexis S. Zajicek, Luke Daly +4 more

Downregulation of Hsp90 and the antimicrobial peptide Mtk suppresses poly(GR)-induced neurotoxicity in C9ORF72-ALS/FTD

Neuron(2023)10.1016/j.neuron.2023.02.029

N/A

0DataRank · unranked

27 citations

Yong‐Woo Jun, Gabriel Linares, Brandon Butler, Yeliz Yuva-Adyemir, Jill E. Moore +9 more

Moderate intrinsic phenotypic alterations in C9orf72 ALS/FTD iPSC-microglia despite the presence of C9orf72 pathological features

Frontiers in Cellular Neuroscience(2023)10.3389/fncel.2023.1179796

N/A

0DataRank · unranked

23 citations

Eric Alsop, Jennifer Lévy, Lauren M. Gittings, Deepti Lall, Benjamin E. Rabichow +27 more

The exocyst complex in neurological disorders

Human Genetics(2023)10.1007/s00439-023-02558-w

N/A

0DataRank · unranked

21 citations

Mary Munson, Fen‐Biao Gao, Dilara O. Halim

Translation of dipeptide repeat proteins in C9ORF72 ALS/FTD through unique and redundant AUG initiation codons

eLife(2023)10.7554/elife.83189

N/A

0DataRank · unranked

14 citations

Soojin Lee, Gopinath Krishnan, Yuanzheng Gu, Deborah Y. Kwon, Fen‐Biao Gao +3 more

Loss of TDP-43 function contributes to genomic instability in amyotrophic lateral sclerosis

Frontiers in Neuroscience(2023)10.3389/fnins.2023.1251228

N/A

0DataRank · unranked

14 citations

Sara K. Evans, Alissa L. Nana, Sarat C. Vatsavayai, Shahid Banday, You Zhou +7 more

Non-muscle MYH10/myosin IIB recruits ESCRT-III to participate in autophagosome closure to maintain neuronal homeostasis

Autophagy(2023)10.1080/15548627.2023.2169309

N/A

0DataRank · unranked

10 citations

Soojin Lee, Byung-Kwan Ban, Jin‐A Lee, Fen‐Biao Gao, Yong‐Woo Jun

Emerging roles of antimicrobial peptides in innate immunity, neuronal function, and neurodegeneration

Trends in Neurosciences(2024)10.1016/j.tins.2024.09.001

N/A

0DataRank · unranked

27 citations

Neal Silverman, Fen‐Biao Gao, Soojin Lee

Poly-GR repeats associated with ALS/FTD gene C9ORF72 impair translation elongation and induce a ribotoxic stress response in neurons

Science Signaling(2024)10.1126/scisignal.adl1030

N/A

0DataRank · unranked

18 citations

Zhe Zhang, Yini Li, Malgorzata J. Latallo, Shaopeng Wang, B.Dean Nelson +6 more

The exocyst subunit EXOC2 regulates the toxicity of expanded GGGGCC repeats in C9ORF72-ALS/FTD

Cell Reports(2024)10.1016/j.celrep.2024.114375

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0DataRank · unranked

1 citations

Gopinath Krishnan, Evan P. Hass, Soojin Lee, Mamta Verma, Sandra Almeida +5 more

Traumatic injury causes selective degeneration and TDP-43 mislocalization in human iPSC-derived C9orf72 -associated ALS/FTD motor neurons

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.21.586073

N/A

0DataRank · unranked

7 citations

Citlally Santacruz, Angela Mitevska, Ian E. Jones, Gopinath Krishnan, Fen‐Biao Gao +3 more

Crucial role of Snf7-3 in synaptic function and cognitive behavior revealed by conventional and conditional knockout mouse models

Neuroscience(2024)10.1016/j.neuroscience.2024.10.010

N/A

0DataRank · unranked

0 citations

Jaewoo Jang, Su-Eon Sim, Jisu Lee, J. H. Jeong, June-Hyun Jeong +8 more

Nemo-like kinase disrupts nuclear import and drives TDP43 mislocalization in ALS

Journal of Clinical Investigation(2025)10.1172/jci188138

N/A

0DataRank · unranked

1 citations

Emile Pinarbasi, Gopinath Krishnan, Jack J. Mesojedec, Madelaine Hurley, Harisankar Harikumar Sheela +12 more

The Ku80-p53-SIRT1 axis in DNA damage response contributes to sporadic and familial ALS and FTD

Nature Communications(2025)10.1038/s41467-025-67749-7

N/A

0DataRank · unranked

1 citations

Soojin Lee, Sandra Almeida, Kristine Freude, Justin K. Ichida, Fen‐Biao Gao +1 more

Altered MICOS Morphology and Mitochondrial Ion Homeostasis Contribute to Poly(GR) Toxicity Associated with C9-ALS/FTD

Cell Reports(2020)10.1016/j.celrep.2020.107989

N/A

0DataRank · unranked

49 citations

Zhihao Wu, Yu Li, Ishaq Tantray, Diego De Stefani, Andrea Mattarei +5 more

New Mouse Lines that Drive Tetracycline-Controlled Gene Expression in a Small Subset of Spinal Cord Dorsal Horn Neurons

eNeuro(2025)10.1523/eneuro.0441-24.2025

N/A

0DataRank · unranked

0 citations

Heather Learnard, Soojin Lee, Yong‐Woo Jun, Fen‐Biao Gao, Eric Fyrberg

Ik2/TBK1 and Hook/Dynein, an adaptor complex for early endosome transport, are genetic modifiers of FTD-associated mutant CHMP2B toxicity in Drosophila

Scientific Reports(2020)10.1038/s41598-020-71097-5

N/A

0DataRank · unranked

17 citations

Ryan J. H. West, M. Pons�, Sean T. Sweeney, Fen‐Biao Gao, Yubing Lu

CRISPR deletion of the C9ORF72 promoter in ALS/FTD patient motor neurons abolishes production of dipeptide repeat proteins and rescues neurodegeneration

Acta Neuropathologica(2020)10.1007/s00401-020-02154-6

N/A

0DataRank · unranked

37 citations

Yu Zhang, Yuanzheng Gu, Mark W. Kankel, Fen‐Biao Gao, Sandra Almeida +1 more