Lynn A. Spruce

Also affiliated with Hospital of the University of Pennsylvania, University of Pennsylvania

Biochemistry, Genetics and Molecular BiologyMedicineImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 24 papers. Top paper: “Neutrophils promote clearance of nuclear debris following acid-induced lung injury”.

Neutrophils promote clearance of nuclear debris following acid-induced lung injury

Blood(2020)10.1182/blood.2020005505

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0DataRank · unranked

19 citations

Andrew J. Paris, Kandace Gollomp, Ning Dai, Kathryn M. Rubey, Ping Wang +5 more

ER-luminal [Ca2+] regulation of InsP3 receptor gating mediated by an ER-luminal peripheral Ca2+-binding protein

eLife(2020)10.7554/elife.53531

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0DataRank · unranked

36 citations

Min Wang, Karthik Mallilankaraman, Riley Payne, Chris McKennan, Jeffrey T. Lock +8 more

Multimodality Assessment of Heart Failure with Preserved Ejection Fraction Skeletal Muscle Reveals Differences in the Machinery of Energy Fuel Metabolism

ESC Heart Failure(2021)10.1002/ehf2.13329

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36 citations

Elizabeth A. Proto, Neil Wilson, Hossein Fazelinia, Hua Ding, Lynn A. Spruce +24 more

FBXW7β isoform drives transcriptional activation of the proinflammatory TNF cluster in human pro-B cells

Blood Advances(2022)10.1182/bloodadvances.2022007910

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9 citations

Katharina E. Hayer, Hossein Fazelinia, Lynn A. Spruce, Mukta Asnani, Kathryn L. Black +6 more

A Coxiella burnetii effector interacts with the host PAF1 complex and suppresses the innate immune response

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.04.20.488957

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0DataRank · unranked

9 citations

Mark A. Boyer, William P. Bradley, Lynn A. Spruce, Hossein Fazelinia, Sunny Shin +1 more

Oxidative stress induces lysosomal membrane permeabilization and ceramide accumulation in retinal pigment epithelial cells

Disease Models & Mechanisms(2023)10.1242/dmm.050066

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0DataRank · unranked

43 citations

Connor S.R. Jankowski, Rayna Marshall, Rohini M Nair, Néstor Gómez, Ahab Alnemri +21 more

Quantitative label-free mass spectrometry reveals content and signaling differences between neonatal and adult platelets

Journal of Thrombosis and Haemostasis(2023)10.1016/j.jtha.2023.12.022

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0DataRank · unranked

28 citations

Patricia Davenport, Hossein Fazelinia, Erin Soule-Albridge, Zhijian Liu, Haorui Zhang +7 more

Neutral sphingomyelinase blockade enhances hematopoietic stem cell fitness through an integrated stress response

Blood(2023)10.1182/blood.2023022147

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9 citations

Seul K Jung, Danielle R. Kobulsky, Hossein Fazelinia, Lynn A. Spruce, Empar Baltasar Pérez +4 more

c-Myc uses Cul4b to preserve genome integrity and promote antiviral CD8+ T cell immunity

Nature Communications(2023)10.1038/s41467-023-42765-7

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0DataRank · unranked

9 citations

Dale Kim, Scott M. Gordon, Kathleen Klinzing, Siera Rosen, Ipsita Guha +10 more

Proteomics identifies novel biomarkers of synovial joint disease in a canine model of mucopolysaccharidosis I

Molecular Genetics and Metabolism(2023)10.1016/j.ymgme.2023.107371

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4 citations

Rahul Gawri, Yian Khai Lau, Lynn A. Spruce, Hossein Fazelinia, Zhirui Jiang +7 more

The Ubiquitin Ligase Itch Skews Light Zone Selection in Germinal Centers

The Journal of Immunology(2023)10.4049/jimmunol.2200824

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0DataRank · unranked

2 citations

Peter Kim, Macaul Crici, Hossein Fazelinia, Lynn A. Spruce, Paula Oliver +2 more

Phosphoproteomics reveals content and signaling differences between neonatal and adult platelets

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.13.557268

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4 citations

Patricia Davenport, Hossein Fazelinia, Zhijian Liu, Haorui Zhang, Hua Ding +5 more

An exploration of mechanisms underlying Desemzia incerta colonization resistance to methicillin-resistant Staphylococcus aureus on the skin

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.11.561853

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0DataRank · unranked

0 citations

Simon AB Knight, Hossein Fazelinia, Lynn A. Spruce, Jennifer Roof, Emily Y. Chu +6 more

Sequential CRISPR screening reveals partial NatB inhibition as a strategy to mitigate alpha-synuclein levels in human neurons

Science Advances(2024)10.1126/sciadv.adj4767

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0DataRank · unranked

17 citations

Nima Naseri, Sarshan R. Pather, Erinc Hallacli, Alain Ndayisaba, Chris Buenaventura +9 more

Lysosomal damage triggers a p38 MAPK-dependent phosphorylation cascade to promote lysophagy via the small heat shock protein HSP27

Current Biology(2024)10.1016/j.cub.2024.10.061

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13 citations

Peace T. Oloko, Tessa C. Fitch, Elizabeth M. Brown, Lynn A. Spruce, Erika L.F. Holzbaur +1 more

CRISPR screen for protein inclusion formation uncovers a role for SRRD in the regulation of intermediate filament dynamics and aggresome assembly

PLoS Genetics(2024)10.1371/journal.pgen.1011138

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5 citations

Sapanna Chantarawong, Edward M. Barbieri, Greg Cajka, Matthew Liu, Lynn A. Spruce +11 more

An exploration of mechanisms underlying Desemzia incerta colonization resistance to methicillin-resistant Staphylococcus aureus on the skin

mSphere(2024)10.1128/msphere.00636-23

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0DataRank · unranked

2 citations

Simon A.B. Knight, Hossein Fazelinia, Lynn A. Spruce, Jennifer Roof, Emily Y. Chu +7 more

Neutrophil-avid nanocarrier uptake by STAT3 dominant-negative hyper-IgE syndrome patient neutrophils

Life Science Alliance(2024)10.26508/lsa.202402618

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0DataRank · unranked

1 citations

Alexandra F. Freeman, Alexander R. Mukhitov, Andrew J. Paris, Susan Lin, Ryan W. Rue +7 more

E3 ligase substrate adaptor SPOP fine-tunes the UPR of pancreatic β cells

Genes & Development(2024)10.1101/gad.352010.124

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0DataRank · unranked

0 citations

Matthew W. Haemmerle, Sabyasachi Sen, Andrea V. Rozo, Shristi Shrestha, Jeeyeon Cha +12 more

The E3 ubiquitin ligase Cul5 regulates hematopoietic stem cell function for steady-state hematopoiesis in mice

Journal of Clinical Investigation(2025)10.1172/jci180913

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0DataRank · unranked

5 citations

Dale Kim, Nadia Porter, Ipsita Guha, Asif A. Dar, Yohaniz Ortega-Burgos +7 more

Proteomic surveys of the mouse heart unveil cardiovascular responses to nitric oxide/cGMP signaling deficiencies

Communications Biology(2025)10.1038/s42003-025-08203-8

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0DataRank · unranked

3 citations

Hossein Fazelinia, Serena Raimo, Hua Ding, Lynn A. Spruce, Maria Symeonidou +8 more

Biosynthetic plasticity enables CD8+ T cell functional resilience under nutrient stress

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.22.632829

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0DataRank · unranked

3 citations

Montana Knight, Krittin Trihemasava, Kelly Rome, Anne‐Sophie Archambault, Ju‐Hee Oh +17 more

Dysregulated Pathways and Potential Biomarkers in Dermatomyositis Plasma-Derived Extracellular Vesicles: A Pilot Study

Journal of Investigative Dermatology(2025)10.1016/j.jid.2025.06.1597

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0DataRank · unranked

0 citations

Mariko Momohara-Ogawa, Muhammad Bashir, Rachita Pandya, Julianne Kleitsch, Felix Chin +7 more

Differential effects of HDAC8 targeting on Foxp3+ Tregs and effector T cells promote antitumor immunity

JCI Insight(2025)10.1172/jci.insight.186461

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0DataRank · unranked

0 citations

Yan Xiong, Liqing Wang, Rongxiang Han, Hossein Fazelinia, Jennifer Roof +4 more