Mark Wunderlich

Cincinnati Children's Hospital Medical Center

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 36 papers. Top paper: “Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion”.

Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion

Cancer Cell(2020)10.1016/j.ccell.2020.04.017

N/A

8.5DataRank · unranked

777 citations

Lei Dong, Yangchan Li, Min Gao, Li Han, Mark Wunderlich +34 more

METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism

Cell stem cell(2023)10.1016/j.stem.2022.12.006

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3.0DataRank · unranked

158 citations

Lei Dong, Keith Leung, Zhicong Zhao, Yangchan Li, Lei Gao +24 more

TET2-mediated mRNA demethylation regulates leukemia stem cell homing and self-renewal

Cell stem cell(2023)10.1016/j.stem.2023.07.001

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2.0DataRank · unranked

106 citations

Meilin Xue, Xiaolan Deng, Lei Dong, Le Xuan Truong Nguyen, Lili Ren +29 more

Spermidine metabolism regulates leukemia stem and progenitor cell function through KAT7 expression in patient-derived mouse models

Science Translational Medicine(2024)10.1126/scitranslmed.adn1285

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0.537DataRank · unranked

17 citations

Jacob M. Berman, Tianyi Ling, Cristiana O’Brien, Rachel Culp-Hill, Julie A. Reisz +21 more

Targeting AML-associated FLT3 mutations with a type I kinase inhibitor

Journal of Clinical Investigation(2020)10.1172/jci127907

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0DataRank · unranked

39 citations

Katelyn Melgar, Lyndsey Bolanos, Kathleen Hueneman, Morgan M. Walker, Jian-kang Jiang +15 more

High-risk LCH in infants is serially transplantable in a xenograft model but responds durably to targeted therapy

Blood Advances(2020)10.1182/bloodadvances.2019032367

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0DataRank · unranked

25 citations

Christa Krupski, Jason Clark, Mark Wunderlich, Robert B. Lorsbach, Michael Grimley +4 more

An In Vivo CRISPR Screening Platform for Prioritizing Therapeutic Targets in AML

Cancer Discovery(2021)10.1158/2159-8290.cd-20-1851

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0DataRank · unranked

78 citations

Clément Larrue, Nastassja K. Scheidegger, Bo Kyung A. Seong, Neekesh V. Dharia, Miljan Kuljanin +17 more

PD-1 Inhibition Enhances Blinatumomab Response in a UCB/PDX Model of Relapsed Pediatric B-Cell Acute Lymphoblastic Leukemia

Frontiers in Oncology(2021)10.3389/fonc.2021.642466

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0DataRank · unranked

28 citations

Nicole Manning, Christina Sexton, Eric O’Brien, Luke Byerly, Cody Stillwell +4 more

Tumor Microenvironment–Derived R-spondins Enhance Antitumor Immunity to Suppress Tumor Growth and Sensitize for Immune Checkpoint Blockade Therapy

Cancer Discovery(2021)10.1158/2159-8290.cd-20-0833

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0DataRank · unranked

24 citations

Qian Xu, Liang Hu, Xiaomei Yan, Xiaomin Feng, Asumi Yokota +16 more

LAMP-5 is an essential inflammatory-signaling regulator and novel immunotherapy target for mixed lineage leukemia-rearranged acute leukemia

Haematologica(2021)10.3324/haematol.2020.257451

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0DataRank · unranked

17 citations

Jason Clark, Matthew Burwinkel, Brenay Greenslade, Mark Wunderlich, Nathan Salomonis +6 more

Momelotinib is a highly potent inhibitor of FLT3-mutant AML

Blood Advances(2021)10.1182/bloodadvances.2021004611

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0DataRank · unranked

19 citations

Zachary Kincaid, Meenu Kesarwani, Arhama Ahmed, Mark Wunderlich, Tahir Latif +3 more

Inhibition of the RacGEF VAV3 by the small molecule IODVA1 impedes RAC signaling and overcomes resistance to tyrosine kinase inhibition in acute lymphoblastic leukemia

Leukemia(2021)10.1038/s41375-021-01455-3

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0DataRank · unranked

12 citations

Anjelika Gasilina, Mark Wunderlich, Yuan Lin, Marcel Buchholzer, Oliver H.F. Krumbach +10 more

Targeting of Cdc42 GTPase in regulatory T cells unleashes anti-tumor T cell immunity

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.23.461402

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0DataRank · unranked

0 citations

Jun-Qi Yang, Mark Wunderlich, Vishnu Modur, Phuong Nguyen, Yuan Li +8 more

The m6A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia

Cancer Cell(2022)10.1016/j.ccell.2022.10.004

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0DataRank · unranked

319 citations

Feng Huang, Zhaojin Yu, Zhenhua Chen, Emily Prince, Yalin Kang +29 more

Targeting of Cdc42 GTPase in regulatory T cells unleashes antitumor T-cell immunity

Journal for ImmunoTherapy of Cancer(2022)10.1136/jitc-2022-004806

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0DataRank · unranked

28 citations

Jun‐Qi Yang, Mark Wunderlich, Vishnu Modur, Phuong Nguyen, Yuan Li +8 more

Rational polypharmacological targeting of FLT3, JAK2, ABL, and ERK1 suppresses the adaptive resistance to FLT3 inhibitors in AML

Blood Advances(2022)10.1182/bloodadvances.2022007486

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0DataRank · unranked

8 citations

Zachary Kincaid, Meenu Kesarwani, Jacob Menke, Joshua Schwieterman, Sekhu Ansari +11 more

Nuclear Vav3 is required for polycomb repression complex-1 activity in B-cell lymphoblastic leukemogenesis

Nature Communications(2022)10.1038/s41467-022-30651-7

N/A

0DataRank · unranked

10 citations

Kyung Hee Chang, Abhishek Kumar Singh, Michael Kotliar, Michael M Desai, Ashley M. Wellendorf +10 more

PDX models of relapsed pediatric AML preserve global gene expression patterns and reveal therapeutic targets

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.31.478534

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0DataRank · unranked

7 citations

Jing Chen, Christina Sexton, Nicole Manning, Luke Byerly, Eric O’Brien +4 more

Asymmetrically Segregated Mitochondria Provide Cellular Memory of Hematopoietic Stem Cell Replicative History and Drive HSC Attrition

Cell stem cell(2020)10.1016/j.stem.2020.01.016

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0DataRank · unranked

214 citations

Jingyi He, James Bartram, José Javier, Juying Xu, Ellen Fjellman +10 more

In vivo development of immune tissue in human intestinal organoids transplanted into humanized mice

Nature Biotechnology(2023)10.1038/s41587-022-01558-x

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0DataRank · unranked

119 citations

Kathryn A. Wikenheiser‐Brokamp, Praneet Chaturvedi, Nambirajan Sundaram, Gillian R. Goddard, Mark Wunderlich +15 more

Paralog-specific signaling by IRAK1/4 maintains MyD88-independent functions in MDS/AML

Blood(2023)10.1182/blood.2022018718

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0DataRank · unranked

51 citations

Chiharu Ishikawa, Puneet Agarwal, Jennifer Yeung, Avery Sampson, Emma Uible +13 more

Repression of TRIM13 by chromatin assembly factor CHAF1B is critical for AML development

Blood Advances(2023)10.1182/bloodadvances.2022009438

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0DataRank · unranked

10 citations

Chiharu Ishikawa, Xiaoqin Zhu, Sean Walulik, Timothy Nixon, Jessica K. Jordan +8 more

ASXL1 mutations are associated with a response to alvocidib and 5-azacytidine combination in myelodysplastic neoplasms

Haematologica(2023)10.3324/haematol.2023.282921

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0DataRank · unranked

7 citations

Qingyu Xu, Nanni Schmitt, Alexander Streuer, Guo Ge, Lyndsey Bolanos +27 more

Kinase-independent role of mTOR and on-/off-target effects of an mTOR kinase inhibitor

Leukemia(2023)10.1038/s41375-023-01987-w

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0DataRank · unranked

5 citations

Mark Wunderlich, Xiongwei Cai, Zijun Yan, Feng Zhang, Ashley Kuenzi Davis +7 more

Data from Tumor Microenvironment–Derived R-spondins Enhance Antitumor Immunity to Suppress Tumor Growth and Sensitize for Immune Checkpoint Blockade Therapy

(2023)10.1158/2159-8290.c.6549403

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0DataRank · unranked

0 citations

Qian Xu, Liang Hu, Xiaomei Yan, Xiaomin Feng, Asumi Yokota +16 more

YTHDF2 promotes ATP synthesis and immune evasion in B cell malignancies

Cell(2024)10.1016/j.cell.2024.11.007

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0DataRank · unranked

69 citations

Chengwu Zeng, Lu Yang, Yuan Che, Meiling Chen, Lillian Sau +24 more

Pyrimidine depletion enhances targeted and immune therapy combinations in acute myeloid leukemia

JCI Insight(2024)10.1172/jci.insight.173646

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0DataRank · unranked

6 citations

Sydney Fobare, Sandip Vibhute, Abeera Mehmood, Dennis C. Vroom, Mariah L. Johnson +28 more

GPR68 supports AML cells through the calcium/calcineurin pro-survival pathway and confers chemoresistance by mediating glucose metabolic symbiosis

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease(2024)10.1016/j.bbadis.2024.167565

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0DataRank · unranked

6 citations

Caleb Hawkins, Lauren Lawley, Tra Mi Phan, Isaac Park, Nicole Joven +9 more

Fusion-specific chromatin profiles mediate transcriptional heterogeneity in MLL-rearranged acute lymphoblastic leukemia

Blood Advances(2024)10.1182/bloodadvances.2024014065

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0DataRank · unranked

0 citations

Michael Kotliar, Sushmitha Vallabh, Anetta Ptasinska, Salam A. Assi, Mark Wunderlich +4 more

ALKBH1 Drives Tumorigenesis and Drug Resistance via tRNA-decoding Reprogramming and Codon-biased Translation

Cancer Discovery(2025)10.1158/2159-8290.cd-24-1043

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0DataRank · unranked

8 citations

Yuan Che, Keren Zhou, Kitty Wang, Wei Li, D. S. Xue +28 more

Targeting of IRAK4 and GSPT1 enhances therapeutic efficacy in AML via c-Myc destabilization

Leukemia(2025)10.1038/s41375-025-02695-3

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0DataRank · unranked

6 citations

Aishlin Hassan, Kwangmin Choi, Joshua Bennett, Tomoya Muto, Courtnee Clough +13 more

DDX6 undergoes phase separation to modulate metabolic plasticity and chemoresistance

Nature Communications(2025)10.1038/s41467-025-66966-4

N/A

0DataRank · unranked

4 citations

Wei Li, Lili Ren, H. Zhang, Lei Dong, Anthony W.H. Chan +17 more

Glutaredoxin 2 is essential for AML survival through mitochondrial permeability transition pore regulation

Blood(2025)10.1182/blood.2025028933

N/A

0DataRank · unranked

3 citations

Cristiana O’Brien, Jonathan St-Germain, Vincent Rondeau, Mary Shi, Jacob M. Berman +23 more

MBNL1 regulates essential alternative RNA splicing patterns in MLL-rearranged leukemia

Nature Communications(2020)10.1038/s41467-020-15733-8

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0DataRank · unranked

75 citations

Arun Gurunathan, Jason Clark, Matthew Burwinkel, Mark Wunderlich, Mikaela R. Berger +7 more

Ontogeny Dictates Oncogenic Potential, Lineage Hierarchy, and Therapy Response in Pediatric Leukemia

Cancer Discovery(2025)10.1158/2159-8290.cd-25-0556

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0DataRank · unranked

2 citations

Shayan Saniei, Nikita Poddar, Isabella G. Martinez, C. Chao, Subrina Persaud +45 more

Cyclosporine enhances the sensitivity to lenalidomide in MDS/AML in vitro

Experimental Hematology(2020)10.1016/j.exphem.2020.05.001

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0DataRank · unranked

14 citations

Aixia Dou, Saran Feng, Ashley Roman-Rivera, Caleb Hawkins, Lauren Lawley +7 more