William C. Mobley

MedicineNeuroscienceBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 33 papers. Top paper: “The history of Down syndrome–associated Alzheimer's disease; past, present, and future”.

The history of Down syndrome–associated Alzheimer's disease; past, present, and future

Alzheimer s & Dementia(2025)10.1002/alz.70158

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0.385DataRank · unranked

12 citations

María Carmona‐Iragui, Ira T. Lott, Elizabeth Head, Thomas Wisniewski, Michael S. Rafii +8 more

Limitations of the human iPSC-derived neuron model for early-onset Alzheimer’s disease

Molecular Brain(2023)10.1186/s13041-023-01063-5

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0.276DataRank · unranked

4 citations

Kenneth W. Henry, Michael Q. Fitzgerald, Koushik Muralidharan, Andrew B. Caldwell, Srinivasan Ramachandran +5 more

Soluble SORLA Enhances Neurite Outgrowth and Regeneration through Activation of the EGF Receptor/ERK Signaling Axis

Journal of Neuroscience(2020)10.1523/jneurosci.0723-20.2020

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0DataRank · unranked

39 citations

Xiao-Peng Xiong, Lu-Lin Jiang, Tongmei Zhang, Lisa Zhou, Alex Campos +6 more

Detailed evaluation of the upper airway in the Dp(16)1Yey mouse model of Down syndrome

Scientific Reports(2020)10.1038/s41598-020-78278-2

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0DataRank · unranked

17 citations

Noriaki Sakai, Tomonori Iwasaki, Timothy C. Doyle, William C. Mobley, Seiji Nishino +1 more

Local TrkB signaling: themes in development and neural plasticity

Cell and Tissue Research(2020)10.1007/s00441-020-03278-7

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26 citations

William C. Mobley, Aaron Johnstone

Therapeutic Reversal of Chemically Induced Parkinson Disease by Converting Astrocytes into Nigral Neurons

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.06.028084

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0DataRank · unranked

2 citations

Jing Hu, Dongyang Zhang, Fan Meng, Xuan Zhang, Yuanchao Xue +6 more

Opportunities, barriers, and recommendations in Down syndrome research

Translational Science of Rare Diseases(2021)10.3233/trd-200090

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0DataRank · unranked

100 citations

Angelika Amon, Leonard Abbeduto, Stamatis Agiovlasitis, Tarek Alsaied, Heather A. Anderson +47 more

Preclinical validation of a potent γ-secretase modulator for Alzheimer’s disease prevention

The Journal of Experimental Medicine(2021)10.1084/jem.20202560

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0DataRank · unranked

74 citations

Moorthi Ponnusamy, Olga Prikhodko, Yuhuan Xie, Can Zhang, Phuong Nguyen +19 more

Impact of increased APP gene dose in Down syndrome and the Dp16 mouse model

Alzheimer s & Dementia(2021)10.1002/alz.12463

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0DataRank · unranked

61 citations

Cassia Overk, Ann Becker, Dominique Derse, Ricardo Albay, Kim Weldy +7 more

Mechanistic Analysis of Age-Related Clinical Manifestations in Down Syndrome

Frontiers in Aging Neuroscience(2021)10.3389/fnagi.2021.700280

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24 citations

Zhuo Xing, Quang-Di Chen, Richard Salvi, Xuming Zhang, Benjamin Tycko +3 more

Normal levels of KIF5 but reduced KLC1 levels in both Alzheimer disease and Alzheimer disease in Down syndrome: evidence suggesting defects in anterograde transport

Alzheimer s Research & Therapy(2021)10.1186/s13195-021-00796-6

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0DataRank · unranked

19 citations

Utpal Das, Gooho Park, William C. Mobley, Xu‐Qiao Chen

Building the Future Therapies for Down Syndrome: The Third International Conference of the T21 Research Society

Molecular Syndromology(2021)10.1159/000514437

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0DataRank · unranked

10 citations

Yann Hérault, Pablo Helguera, María Martínez de Lagrán, Anna Vazquez, Bradley T. Christian +29 more

Reduced synaptic proteins and SNARE complexes in Down syndrome with Alzheimer's disease and the Dp16 mouse Down syndrome model: Impact of APP gene dose

Alzheimer s & Dementia(2022)10.1002/alz.12835

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21 citations

Xinxin Zuo, Ann Becker, Elizabeth Head, William C. Mobley, Xu‐Qiao Chen

Prenatal and Postnatal Pharmacotherapy in Down Syndrome: The Search to Prevent or Ameliorate Neurodevelopmental and Neurodegenerative Disorders

The Annual Review of Pharmacology and Toxicology(2022)10.1146/annurev-pharmtox-041521-103641

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0DataRank · unranked

15 citations

Stefano Vicari, William C. Mobley, Renata Bartesaghi

CryoET Reveals Organelle Phenotypes in Huntington Disease Patient iPSC-Derived and Mouse Primary Neurons

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.26.485912

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0DataRank · unranked

4 citations

Charlene Smith-Geater, Jesús G. Galaz-Montoya, Yingli Gu, Sanket Rajan Gupte, Ranen Aviner +15 more

CryoET Reveals Organelle Phenotypes in Huntington Disease Patient iPSC-Derived and Mouse Primary Neurons

Research Square(2022)10.21203/rs.3.rs-1493068/v1

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0DataRank · unranked

3 citations

Gong‐Her Wu, Jesús G. Galaz-Montoya, Michael F. Schmid, Lydia‐Marie Joubert, Patrick Mitchell +15 more

CryoET reveals organelle phenotypes in huntington disease patient iPSC-derived and mouse primary neurons

Nature Communications(2023)10.1038/s41467-023-36096-w

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0DataRank · unranked

67 citations

Charlene Smith-Geater, Jesús G. Galaz-Montoya, Yingli Gu, Sanket Rajan Gupte, Ranen Aviner +16 more

Therapeutic Potential of PTB Inhibition Through Converting Glial Cells to Neurons in the Brain

Annual Review of Neuroscience(2023)10.1146/annurev-neuro-083022-113120

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0DataRank · unranked

16 citations

William C. Mobley, Xiang‐Dong Fu

Retromer Proteins Reduced in Down Syndrome and the Dp16 Model: Impact ofAPPDose and Preclinical Studies of a γ‐Secretase Modulator

Annals of Neurology(2023)10.1002/ana.26659

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0DataRank · unranked

12 citations

Mariko Sawa, Ann Becker, Dmitry Karachentsev, Xinxin Zuo, Kevin D. Rynearson +3 more

Alzheimer’s disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling

eLife(2023)10.7554/elife.90690

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0DataRank · unranked

7 citations

Utpal Das, Sam Lismont, Thomas Enzlein, Masato Maesako, Mei CQ Houser +11 more

Alzheimer’s disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.02.551596

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0DataRank · unranked

5 citations

Utpal Das, Sam Lismont, Thomas Enzlein, Masato Maesako, Mei CQ Houser +11 more

WITHDRAWN: I feel your pain: Higher empathy is associated with higher posterior default mode network activity

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.11.553004

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0DataRank · unranked

1 citations

Gabriel Riegner, Jon G. Dean, Lora Khatib, Alessandro Allen, Daniel Barrows +12 more

Alzheimer’s disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling

(2023)10.7554/elife.90690.1

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0DataRank · unranked

0 citations

Utpal Das, Sam Lismont, Thomas Enzlein, Masato Maesako, CQ Houser Mei +10 more

Author Response: Alzheimer’s disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling

(2023)10.7554/elife.90690.1.sa3

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0DataRank · unranked

0 citations

Utpal Das, Sam Lismont, Thomas Enzlein, Masato Maesako, CQ Houser Mei +10 more

γ‐Secretase Modulator BPN15606 Reduced Aβ42 and Aβ40 and Countered Alzheimer‐Related Pathologies in a Mouse Model of Down Syndrome

Annals of Neurology(2024)10.1002/ana.26958

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0DataRank · unranked

13 citations

Ann Becker, Ricardo Albay, Phuong D. Nguyen, Dmitry Karachentsev, Amanda J. Roberts +4 more

BDNF and TRiC-inspired reagent rescue cortical synaptic deficits in a mouse model of Huntington's disease

Neurobiology of Disease(2024)10.1016/j.nbd.2024.106502

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8 citations

Alexander Pope, Charlene Smith, Christopher Carmona, Aaron Johnstone, Linda Shi +10 more

Author response: Alzheimer’s disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling

(2024)10.7554/elife.90690.2.sa2

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0DataRank · unranked

0 citations

Utpal Das, Sam Lismont, Thomas Enzlein, Masato Maesako, Mei CQ Houser +11 more

Alzheimer’s disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling

eLife(2024)10.7554/elife.90690.3

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0DataRank · unranked

0 citations

Utpal Das, Sam Lismont, Thomas Enzlein, Masato Maesako, Mei CQ Houser +11 more

Hyperactivation of RAB5 disrupts the endosomal Rab cascade leading to endolysosomal dysregulation in Down syndrome: A necessary role for increased APP gene dose

Alzheimer s & Dementia(2025)10.1002/alz.70046

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0DataRank · unranked

9 citations

Xinxin Zuo, Ann Becker, William C. Mobley, Xu‐Qiao Chen

Antisense oligonucleotides directed against App and Rab5 normalized endosomal Rab activity and reversed DS‐AD‐linked degenerative phenotypes in the Dp16 mouse model of Down syndrome

Alzheimer s & Dementia(2025)10.1002/alz.70022

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0DataRank · unranked

8 citations

Xinxin Zuo, Ann Becker, Michael Mante, Jazmin Florio, Satish Jadhav +8 more

Enabling Technologies for Personalized and Precision Medicine

Trends in biotechnology(2020)10.1016/j.tibtech.2019.12.021

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0DataRank · unranked

494 citations

Stephen R. Quake, Edward R.B. McCabe, Wee Joo Chng, Edward Kai‐Hua Chow, Xianting Ding +11 more

Tau pathology differs by sex in Alzheimer's disease in Down syndrome

Alzheimer s & Dementia(2025)10.1002/alz.70838

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0DataRank · unranked

4 citations

Xinxin Zuo, William C. Mobley, Xu‐Qiao Chen

Reversing a model of Parkinson’s disease with in situ converted nigral neurons

Nature(2020)10.1038/s41586-020-2388-4

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0DataRank · unranked

489 citations

Xinjiang Kang, Jing Hu, Dongyang Zhang, Zhengyu Liang, Fan Meng +10 more