David J. Weber

Also affiliated with National Institute of Standards and Technology, University of North Carolina Health Care, Research Institute for Bioscience and Biotechnology, Institute for Bioscience and Biotechnology Research, University of Maryland, College Park

Biochemistry, Genetics and Molecular BiologySocial SciencesComputer ScienceImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 36 papers. Top paper: “Structure of the cell-binding component of the Clostridium difficile binary toxin reveals a di-heptamer macromolecular assembly”.

Structure of the cell-binding component of the Clostridium difficile binary toxin reveals a di-heptamer macromolecular assembly

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.1919490117

N/A

1.1DataRank · unranked

37 citations

Raquel Godoy‐Ruiz, Kaylin A. Adipietro, Christopher Peralta, Danya Ben-Hail, Kristen M. Varney +20 more

Targeted Degradation of Androgen Receptor by VNPP433-3β in Castration-Resistant Prostate Cancer Cells Implicates Interaction with E3 Ligase MDM2 Resulting in Ubiquitin-Proteasomal Degradation

Cancers(2023)10.3390/cancers15041198

N/A

0.434DataRank · unranked

17 citations

Retheesh S. Thankan, Puranik Purushottamachar, David J. Weber, Vincent C.O. Njar, Elizabeth Thomas

Specificity of Molecular Fragments Binding to S100B versus S100A1 as Identified by NMR and Site Identification by Ligand Competitive Saturation (SILCS)

Molecules(2021)10.3390/molecules26020381

N/A

0.373DataRank · unranked

11 citations

Wenbo Yu, Darex J. Vera Rodríguez, Kristen M. Varney, Alexander D. MacKerell, David J. Weber +1 more

Hospital-Acquired Clostridium difficile Infections: Estimating All-Cause Mortality and Length of Stay

UNC Libraries(2020)10.17615/az7n-qq22

N/A

0.269DataRank · unranked

5 citations

Stephen R. Cole, Rebekah W. Moehring, David J. Weber, Eric Lofgren, Deverick J. Anderson

VNLG-152R and its deuterated analogs potently inhibit/repress triple/quadruple negative breast cancer of diverse racial origins in vitro and in vivo by upregulating E3 Ligase Synoviolin 1 (SYVN1) and inducing proteasomal degradation of MNK1/2

Frontiers in Oncology(2023)10.3389/fonc.2023.1240996

N/A

0.241DataRank · unranked

4 citations

Elizabeth Thomas, Puranik Purushottamachar, David J. Weber, Vidya P. Ramamurthy, Weiliang Huang +3 more

Detection of Putative Ligand Dissociation Pathways in Proteins Using Site-Identification by Ligand Competitive Saturation

Journal of Chemical Information and Modeling(2024)10.1021/acs.jcim.4c01814

N/A

0.241DataRank · unranked

4 citations

David J. Weber, Alexander D. MacKerell, Wenbo Yu

1H, 13C, and 15N assignments of the mRNA binding protein hnRNP A18

Biomolecular NMR Assignments(2022)10.1007/s12104-022-10117-z

N/A

0.208DataRank · unranked

3 citations

Braden M. Roth, Kristen M. Varney, France Carrier, David J. Weber, Katherine M. Coburn

Initial exploration of a novel fusion protein, IL-4/IL-34/IL-10, which promotes cardiac allograft survival mice through alloregulation

Innate Immunity(2023)10.1177/17534259231186239

N/A

0.104DataRank · unranked

1 citations

I-Ting Cheng, Godoy-Ruiz Raquel, David J. Weber, Joseph R. Scalea, Young Shin Lee

Computer-Aided Drug Design: An Update

Methods in molecular biology(2022)10.1007/978-1-0716-2855-3_7

N/A

0DataRank · unranked

18 citations

David J. Weber, Alexander D. MacKerell, Wenbo Yu

Novel AR/AR-V7 and Mnk1/2 Degrader, VNPP433-3β: Molecular Mechanisms of Action and Efficacy in AR-Overexpressing Castration Resistant Prostate Cancer In Vitro and In Vivo Models

Cells(2022)10.3390/cells11172699

N/A

0DataRank · unranked

15 citations

Retheesh S. Thankan, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang +4 more

Binding and Functional Folding (BFF): A Physiological Framework for Studying Biomolecular Interactions and Allostery

Journal of Molecular Biology(2022)10.1016/j.jmb.2022.167872

N/A

0DataRank · unranked

8 citations

Mary E. Cook, Brianna K. Costabile, Riya Samanta, Xinhao Zhuang, Spiridon E. Sevdalis +6 more

CD36 homologs determine microbial resistance to the Lyme disease spirochete

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.09.479763

N/A

0DataRank · unranked

0 citations

Nisha Singh, Iain S. Forrest, Agustín Rolandelli, Xiaowei Wang, Dana K. Shaw +17 more

1H, 13C, and 15N assignments of the mRNA binding protein hnRNP A18

Research Square(2022)10.21203/rs.3.rs-2187364/v1

N/A

0DataRank · unranked

0 citations

Braden M. Roth, Kristen M. Varney, France Carrier, David J. Weber, Katherine M. Coburn

Structure-Based Design of Potent Iminosugar Inhibitors of Endoplasmic Reticulum α-Glucosidase I with Anti-SARS-CoV-2 Activity

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.2c01750

N/A

0DataRank · unranked

24 citations

Evelyn J. Franco, Ana C. Rojas, Kaley C. Hanrahan, A. V. Kolesnikov, Wenbo Yu +7 more

Integrated Covalent Drug Design Workflow Using Site Identification by Ligand Competitive Saturation

Journal of Chemical Theory and Computation(2023)10.1021/acs.jctc.3c00232

N/A

0DataRank · unranked

12 citations

David J. Weber, Alexander D. MacKerell, Wenbo Yu

Salinization Dramatically Enhance the Anti-Prostate Cancer Efficacies of AR/AR-V7 and Mnk1/2 Molecular Glue Degraders, Galeterone and VNPP433-3β Which Outperform Docetaxel and Enzalutamide in CRPC CWR22Rv1 Xenograft Mouse Model

Bioorganic Chemistry(2023)10.1016/j.bioorg.2023.106700

N/A

0DataRank · unranked

11 citations

Elizabeth Thomas, Puranik Purushottamachar, David J. Weber, Vincent C.O. Njar, Retheesh S. Thankan

An Integrated Covalent Drug Design Workflow using Site-Identification by Ligand Competitive Saturation

ChemRxiv(2023)10.26434/chemrxiv-2023-sc37c

N/A

0DataRank · unranked

0 citations

David J. Weber, Alexander D. MacKerell, Wenbo Yu

Data from Deletion of PTEN Promotes Tumorigenic Signaling, Resistance to Anoikis, and Altered Response to Chemotherapeutic Agents in Human Mammary Epithelial Cells

(2023)10.1158/0008-5472.c.6499844.v1

N/A

0DataRank · unranked

0 citations

Michele B. Weiss, Marta Szmacinski, Khola Tahir, Todd Waldman, Ben Ho Park +4 more

Membrane binding and pore formation is Ca 2+ -dependent for the Clostridioides difficile binary toxin

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.18.553786

N/A

0DataRank · unranked

0 citations

Spiridon E. Sevdalis, Kaylin A. Adipietro, Raquel Godoy‐Ruiz, Kristen M. Varney, Izza F. Nawaz +8 more

Deuterium spin relaxation of fractionally deuterated ribonuclease H using paired 475 and 950 MHz NMR spectrometers

Journal of Biomolecular NMR(2024)10.1007/s10858-024-00443-w

N/A

0DataRank · unranked

3 citations

Kristen M. Varney, Tassadite Dahmane, Bruce A. Johnson, David J. Weber, Arthur G. Palmer +1 more

Mitophagosomes induced during EV-D68 infection promote viral nonlytic release

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.12.05.627125

N/A

0DataRank · unranked

2 citations

Bimal Paudel, Michael A. Wagner, Noah Pollack, I-Ting Cheng, Raquel Godoy‐Ruiz +3 more

Structural and Functional Insights into the Delivery Systems of Bacillus and Clostridial Binary Toxins

Toxins(2024)10.3390/toxins16080330

N/A

0DataRank · unranked

0 citations

Kristen M. Varney, Mary E. Cook, Joseph J. Gillespie, Edwin Pozharski, David J. Weber +1 more

Unveiling the intricate role of S100A1 in regulating RyR1 activity: A commentary on “Structural insights into the regulation of RyR1 by S100A1”

Cell Calcium(2024)10.1016/j.ceca.2024.102947

N/A

0DataRank · unranked

0 citations

Kristen M. Varney, Pratyush Tiwary, David J. Weber, Erick O. Hernández‐Ochoa, Megan L. Perry

Rational design of flavivirus E protein vaccine optimizes immunogenicity and mitigates antibody dependent enhancement risk

Nature Communications(2025)10.1038/s41467-025-67447-4

N/A

0DataRank · unranked

6 citations

Andrey Galkin, Xiaoran Shang, Alexander Marin, Shaohua Jin, Ting-Juan Ye +23 more

Pore formation by the CDTb component of the Clostridioides difficile binary toxin is Ca2+-dependent

Communications Biology(2025)10.1038/s42003-025-08343-x

N/A

0DataRank · unranked

3 citations

Spiridon E. Sevdalis, Kaylin A. Adipietro, Raquel Godoy‐Ruiz, Kristen M. Varney, Izza F. Nawaz +9 more

Bile Acids Are Potential Negative Allosteric Modulators of M1 Muscarinic Receptors

Biomolecules(2025)10.3390/biom15091326

N/A

0DataRank · unranked

1 citations

Alexander D. MacKerell, David J. Weber, Jean‐Pierre Raufman, Wenbo Yu

High Throughput Ligand Dissociation Kinetics Predictions using Site-Identification by Ligand Competitive Saturation

ChemRxiv(2025)10.26434/chemrxiv-2025-5bc2t

N/A

0DataRank · unranked

0 citations

Shashi Kumar, Mingtian Zhao, David J. Weber, Alexander D. MacKerell, Wenbo Yu

Small molecules inhibitors of the heterogeneous ribonuclear protein A18 (hnRNP A18): a regulator of protein translation and an immune checkpoint

Nucleic Acids Research(2020)10.1093/nar/gkaa1254

N/A

0DataRank · unranked

17 citations

Katherine M. Coburn, Wenbo Yu, Gerald M. Wilson, Elmar Nurmemmedov, Santosh Kesari +5 more

High Throughput Ligand Dissociation Kinetics Predictions using Site-Identification by Ligand Competitive Saturation

ChemRxiv(2025)10.26434/chemrxiv-2025-5bc2t-v2

N/A

0DataRank · unranked

0 citations

Shashi Kumar, Mingtian Zhao, David J. Weber, Alexander D. MacKerell, Wenbo Yu

1HN, 13C, and 15N resonance assignments of the Clostridioides difficile receptor binding domain 2 (CDTb, residues 757–876)

Biomolecular NMR Assignments(2020)10.1007/s12104-020-09979-y

N/A

0DataRank · unranked

0 citations

Kristen M. Varney, Raquel Godoy‐Ruiz, David J. Weber, Mary E. Cook

Sulforaphane covalently interacts with the transglutaminase 2 cancer maintenance protein to alter its structure and suppress its activity

Molecular Carcinogenesis(2021)10.1002/mc.23356

N/A

0DataRank · unranked

16 citations

Gautam Adhikary, Henryk Szmacinski, Joseph R. Lakowicz, David J. Weber, Raquel Godoy‐Ruiz +5 more

Physiologically Relevant Free Ca2+ Ion Concentrations Regulate STRA6-Calmodulin Complex Formation via the BP2 Region of STRA6

Journal of Molecular Biology(2021)10.1016/j.jmb.2021.167272

N/A

0DataRank · unranked

10 citations

Kristen M. Varney, Paul T. Wilder, Brianna K. Costabile, Edwin Pozharski, Mary E. Cook +5 more

1HN, 13C, and 15N backbone resonance assignments of the SET/TAF-1β/I2PP2A oncoprotein (residues 23–225)

Biomolecular NMR Assignments(2021)10.1007/s12104-021-10034-7

N/A

0DataRank · unranked

3 citations

Ryan De Palma, Mary E. Cook, Kristen M. Varney, David J. Weber, Besim Öğretmen +1 more

The calcium-binding protein S100B reduces IL6 production in malignant melanoma via inhibition of RSK cellular signaling

PLoS ONE(2021)10.1371/journal.pone.0256238

N/A

0DataRank · unranked

3 citations

Alexander R. Terry, Adam D. Pierce, Michael C. Cavalier, Catherine Blaha, Kaylin A. Adipietro +4 more

A Novel Organometallic Rhenium Salt: DNA-Binding and Cytotoxicity Studies on Pancreatic, Breast and Lymphoma Cancers

Research Square(2021)10.21203/rs.3.rs-165666/v1

N/A

0DataRank · unranked

0 citations

Birsen Y. Varisli, Angela J. Winstead, Paul T. Wilder, David J. Weber, Fazlul H. Sarkar +10 more

Transcriptome profiling reveals that VNPP433‐3β, the lead next‐generation galeterone analog inhibits prostate cancer stem cells by downregulating epithelial–mesenchymal transition and stem cell markers

Molecular Carcinogenesis(2022)10.1002/mc.23406

N/A

0DataRank · unranked

31 citations

Retheesh S. Thankan, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang +4 more