Alan Engelman

Also affiliated with Dana-Farber Cancer Institute, Dana-Farber/Harvard Cancer Center

Immunology and MicrobiologyMedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 52 papers. Top paper: “HIV-1 usurps mixed-charge domain-dependent CPSF6 phase separation for higher-order capsid binding, nuclear entry and viral DNA integration”.

HIV-1 usurps mixed-charge domain-dependent CPSF6 phase separation for higher-order capsid binding, nuclear entry and viral DNA integration

Nucleic Acids Research(2024)10.1093/nar/gkae769

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0.535DataRank · unranked

24 citations

Gregory J. Bedwell, Satya P. Singh, Hyun Jae Yu, Bjarki Arnarson, Parmit K. Singh +14 more

Interplay between the cyclophilin homology domain of RANBP2 and MX2 regulates HIV-1 capsid dependencies on nucleoporins

mBio(2025)10.1128/mbio.02646-24

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0.178DataRank · unranked

2 citations

Ananya Venbakkam, Parmit K. Singh, Bailey Layish, Szu‐Wei Huang, Rajalingam Radhakrishnan +4 more

Structural basis of second-generation HIV integrase inhibitor action and viral resistance

Science(2020)10.1126/science.aay4919

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0DataRank · unranked

107 citations

Wen Li, Denes Berta, Magd Badaoui, Allison Ballandras-Colas, Andrea Nans +5 more

Permeability of the HIV-1 capsid to metabolites modulates viral DNA synthesis

PLoS Biology(2020)10.1371/journal.pbio.3001015

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72 citations

D Fischer, Sanela Rankovic, Wen Li, Robert A. Dick, Brent Runge +9 more

Integrase-RNA interactions underscore the critical role of integrase in HIV-1 virion morphogenesis

eLife(2020)10.7554/elife.54311

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0DataRank · unranked

57 citations

Jenna E. Eschbach, Pratibha C. Koneru, Wen Li, Maritza Puray‐Chavez, Dana Townsend +5 more

A Peptide Derived from Lens Epithelium–Derived Growth Factor Stimulates HIV-1 DNA Integration and Facilitates Intasome Structural Studies

Journal of Molecular Biology(2020)10.1016/j.jmb.2020.01.040

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0DataRank · unranked

18 citations

Xuemin Chen, Huaibin Wang, Kellie A. Jurado, Alan Engelman, Robert Craigie +1 more

The HIV-1 capsid-binding host factor CPSF6 is post-transcriptionally regulated by the cellular microRNA miR-125b

Journal of Biological Chemistry(2020)10.1074/jbc.ra119.010534

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0DataRank · unranked

18 citations

Sabyasachi Dash, Muthukumar Balasubramaniam, Adrian Padron, Joseph Holland, Gregory A. Sowd +5 more

Factors that mold the nuclear landscape of HIV-1 integration

Nucleic Acids Research(2020)10.1093/nar/gkaa1207

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0DataRank · unranked

40 citations

Alan Engelman, Gregory J. Bedwell

Permeability of the HIV-1 capsid to metabolites modulates viral DNA synthesis

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.30.071217

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14 citations

D Fischer, Sanela Rankovic, Wen Li, Rob Dick, Brent Runge +9 more

Cytoplasmic CPSF6 regulates HIV-1 capsid trafficking and infection in a cyclophilin A-dependent manner

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.05.136697

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6 citations

Jiying Ning, Emerson Ailidh Boggs, Sooin Jang, Callen T. Wallace, Cheryl A. Telmer +7 more

A DNA-origami nuclear pore mimic reveals nuclear entry mechanisms of HIV-1 capsid

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.10.245522

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0DataRank · unranked

6 citations

Chaoyi Xu, Sooin Jang, Qiancheng Xiong, Swapnil C. Devarkar, Taoran Tian +13 more

Capsid lattice destabilization leads to premature loss of the viral genome and integrase enzyme during HIV-1 infection

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.26.009902

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5 citations

Jennifer L. Elliott, Wen Li, Kaneil K. Zadrozny, Keanu Davis, Shawn Mohammed +5 more

A highly potent and safe pyrrolopyridine-based allosteric HIV-1 integrase inhibitor targeting host LEDGF/p75-integrase interaction site

PLoS Pathogens(2021)10.1371/journal.ppat.1009671

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39 citations

Seohyun Ahn, Uk-Il Kim, Jared Lindenberger, Adrian Oo, Pratibha C. Koneru +6 more

HIV Capsid and Integration Targeting

Viruses(2021)10.3390/v13010125

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56 citations

Alan Engelman

rigrag: high-resolution mapping of genic targeting preferences during HIV-1 integration in vitro and in vivo

Nucleic Acids Research(2021)10.1093/nar/gkab514

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30 citations

Sooin Jang, Wen Li, Parmit K. Singh, Alan Engelman, Gregory J. Bedwell

Long-Acting Cabotegravir for HIV/AIDS Prophylaxis

Biochemistry(2021)10.1021/acs.biochem.1c00157

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24 citations

Alan Engelman, Kathleen Engelman

Intra- and extra-cellular environments contribute to the fate of HIV-1 infection

Cell Reports(2021)10.1016/j.celrep.2021.109622

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0DataRank · unranked

24 citations

Miranda Harris, Angela Chov, Zachary T. Herbert, Vladimir Vrbanac, Maud Déruaz +5 more

HIV-1 integrase binding to genomic RNA 5′-UTR induces local structural changes in vitro and in virio

Retrovirology(2021)10.1186/s12977-021-00582-0

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10 citations

Pratibha C. Koneru, Wen Li, Chathuri Pathirage, Alan Engelman, Mamuka Kvaratskhelia +2 more

D614G and SARS-CoV-2 replication fitness

Signal Transduction and Targeted Therapy(2021)10.1038/s41392-021-00498-3

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1 citations

Alan Engelman, Kathleen Engelman

The mouse mammary tumor virus intasome exhibits distinct dynamics on target DNA

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.17.468995

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0DataRank · unranked

1 citations

Nathan D. Jones, Allison Ballandras-Colas, Alan Engelman, Richard Fishel, Kristine E. Yoder +1 more

Prion-like low complexity regions enable avid virus-host interactions during HIV-1 infection

Nature Communications(2022)10.1038/s41467-022-33662-6

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0DataRank · unranked

59 citations

Naseer Iqbal, Valentine V. Courouble, Ashwanth C. Francis, Parmit K. Singh, Arpa Hudait +14 more

Multimodal Functionalities of HIV-1 Integrase

Viruses(2022)10.3390/v14050926

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33 citations

Mamuka Kvaratskhelia, Alan Engelman

Localization and functions of native and eGFP-tagged capsid proteins in HIV-1 particles

PLoS Pathogens(2022)10.1371/journal.ppat.1010754

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0DataRank · unranked

26 citations

Anna Cereseto, Parmit K. Singh, Jiong Shi, Eric M. Poeschla, Alan Engelman +3 more

Multivalent interactions essential for lentiviral integrase function

Nature Communications(2022)10.1038/s41467-022-29928-8

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0DataRank · unranked

24 citations

Vidya Chivukula, Dominika T. Gruszka, Zelin Shan, Parmit K. Singh, Valerie E. Pye +15 more

B-to-A transition in target DNA during retroviral integration

Nucleic Acids Research(2022)10.1093/nar/gkac644

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0DataRank · unranked

21 citations

Wen Li, Dawei Zhang, Doris Wong, Julia Grawenhoff, Allison Ballandras-Colas +5 more

Allosteric Integrase Inhibitor Influences on HIV-1 Integration and Roles of LEDGF/p75 and HDGFL2 Host Factors

Viruses(2022)10.3390/v14091883

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12 citations

Wen Li, Gregory J. Bedwell, Hind J. Fadel, Eric M. Poeschla, Alan Engelman +1 more

Genome-wide CRISPR/Cas9 transcriptional activation screen identifies a histone acetyltransferase inhibitor complex as a regulator of HIV-1 integration

Nucleic Acids Research(2022)10.1093/nar/gkac464

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15 citations

Shaobo Wang, Wanyu Li, Edwin Yau, Hui Hui, Parmit K. Singh +5 more

Multivalent interactions essential for lentiviral integrase function

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.26.477893

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1 citations

Vidya Chivukula, Dominika T. Gruszka, Zelin Shan, Parmit K. Singh, Valerie E. Pye +15 more

Modeling HIV-1 nuclear entry with nucleoporin-gated DNA-origami channels

Nature Structural & Molecular Biology(2023)10.1038/s41594-023-00925-9

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0DataRank · unranked

53 citations

Qingzhou Feng, Chunxiang Wu, Qiancheng Xiong, Taoran Tian, Shuai Yuan +9 more

Viral and host mediators of non-suppressible HIV-1 viremia

Nature Medicine(2023)10.1038/s41591-023-02611-1

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49 citations

Behzad Etemad, Xin Zhang, Yijia Li, Gregory J. Bedwell, Radwa Sharaf +35 more

The capsid lattice engages a bipartite NUP153 motif to mediate nuclear entry of HIV-1 cores

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2202815120

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46 citations

Sushila Kumari, Chaoyi Xu, Sooin Jang, Jiong Shi, Ryan C. Burdick +18 more

Capsid–host interactions for HIV-1 ingress

Microbiology and Molecular Biology Reviews(2023)10.1128/mmbr.00048-22

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0DataRank · unranked

44 citations

Alan Engelman, Sooin Jang

The Drug-Induced Interface That Drives HIV-1 Integrase Hypermultimerization and Loss of Function

mBio(2023)10.1128/mbio.03560-22

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18 citations

Tung Dinh, Lev Levintov, Arun S. Annamalai, Juan S. Rey, Lorenzo Briganti +10 more

Pathways and Intersections: Multifaceted Approaches to Engage Individuals From Underrepresented and Marginalized Communities in HIV Research and Career Development

JAIDS Journal of Acquired Immune Deficiency Syndromes(2023)10.1097/qai.0000000000003265

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0DataRank · unranked

6 citations

Pooja Chitneni, Tiffany R. Glynn, Wanda Allen, Peter R. Chai, Alan Engelman +11 more

Viral and Host Mediators of Non-Suppressible HIV-1 Viremia

medRxiv(2023)10.1101/2023.03.30.23287124

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6 citations

Behzad Etemad, Xin Zhang, Yijia Li, Gregory J. Bedwell, Radwa Sharaf +31 more

HIV-1 Intasomes Assembled with Excess Integrase C-Terminal Domain Protein Facilitate Structural Studies by Cryo-EM and Reveal the Role of the Integrase C-Terminal Tail in HIV-1 Integration

Viruses(2024)10.3390/v16071166

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12 citations

Zhen Li, Xuemin Chen, Yanxiang Cui, Alan Engelman, Robert Craigie +1 more

Brief Histories of Retroviral Integration Research and Associated International Conferences

Viruses(2024)10.3390/v16040604

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7 citations

Alan Engelman, Duane P. Grandgenett

Spatiotemporal binding of cyclophilin A and CPSF6 to capsid regulates HIV-1 nuclear entry and integration

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.08.588584

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10 citations

Christopher E. Kline, Alexandra K. Hughson, Parmit K. Singh, Hannah L. Fischer, Gregory A. Sowd +5 more

Oligomeric HIV-1 Integrase Structures Reveal Functional Plasticity for Intasome Assembly and RNA Binding

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.26.577436

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4 citations

Zelin Shan, Tung Dinh, Avik Biswas, Sooin Jang, Juliet Greenwood +16 more

Disruption of LEDGF/p75-directed integration derepresses antisense transcription of the HIV-1 genome

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.12.06.627169

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3 citations

Darius Mahboubi, Maritza Puray‐Chavez, Raven Shah, Obiaara B. Ukah, Claudia C. Wahoski +14 more

Spatiotemporal binding of cyclophilin A and CPSF6 to capsid regulates HIV-1 nuclear entry and integration

mBio(2025)10.1128/mbio.00169-25

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7 citations

Christopher E. Kline, Alexandra K. Hughson, Parmit K. Singh, Hannah L. Fischer, Rajalingham Radhakrishnan +8 more

Oligomeric HIV-1 integrase structures reveal functional plasticity for intasome assembly and RNA binding

Nature Communications(2025)10.1038/s41467-025-64479-8

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0DataRank · unranked

4 citations

Zelin Shan, Tung Dinh, Avik Biswas, Sooin Jang, Juliet Greenwood +16 more

The nuclear localization signal of CPSF6 governs post-nuclear import steps of HIV-1 infection

PLoS Pathogens(2025)10.1371/journal.ppat.1012354

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7 citations

Rajalingam Radhakrishnan, Parmit K. Singh, Gregory J. Bedwell, Alan Engelman, Adarsh Dharan +2 more

CPSF6 promotes HIV-1 preintegration complex function

Journal of Virology(2025)10.1128/jvi.00490-25

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4 citations

Sooin Jang, Rajasree Chakraborty, Rajalingam Radhakrishnan, Bjarki Arnarson, Prem Prakash +11 more

Timed chromatin invasion during mitosis governs prototype foamy virus integration site selection and infectivity

Nucleic Acids Research(2025)10.1093/nar/gkaf449

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1 citations

Parmit K. Singh, Christina Calmels, Delphine Lapaillerie, Dirk Lindemann, Vincent Parissi +4 more

Development and validation of HIV SMRTcap for the characterization of HIV-1 reservoirs across tissues and subtypes

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.01.651657

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3 citations

Steven T. Nadakal, William C. Lauer, Justin T. Kos, Parmit K. Singh, Erin Elliott +29 more

CPSF6 Promotes HIV-1 Preintegration Complex Function

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.28.635394

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0 citations

Sooin Jang, Rajasree Chakraborty, Rajalingam Radhakrishnan, Bjarki Arnarson, Prem Prakash +11 more

Retrointegration2023—Papers from the 7th International Conference on Retroviral Integration

Viruses(2025)10.3390/v17070879

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0 citations

Duane P. Grandgenett, Goedele N. Maertens, Kristine E. Yoder, Mamuka Kvaratskhelia, Alan Engelman

In vitro integration site sequencing for "Core nucleosomes are refractory to lentiviral DNA integration: the role of cellular LEDGF/p75 protein"

Zenodo (CERN European Organization for Nuclear Research)(2025)10.5281/zenodo.17566487

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0DataRank · unranked

0 citations

Emma K. Punch, Nicola Cook, Singer, Matthew, Joshi, Dhira, Parmit K. Singh +5 more

HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains

Nature Communications(2020)10.1038/s41467-020-17256-8

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0DataRank · unranked

172 citations

Mariana Marin, Parmit K. Singh, Vasudevan Achuthan, M Prellberg, Kristina Palermino-Rowland +6 more

In vitro integration site sequencing for "Core nucleosomes are refractory to lentiviral DNA integration: the role of cellular LEDGF/p75 protein"

Zenodo (CERN European Organization for Nuclear Research)(2025)10.5281/zenodo.17566488

N/A

0DataRank · unranked

0 citations

Emma K. Punch, Nicola Cook, Singer, Matthew, Joshi, Dhira, Parmit K. Singh +5 more

Distinct viral reservoirs in individuals with spontaneous control of HIV-1

Nature(2020)10.1038/s41586-020-2651-8

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0DataRank · unranked

422 citations

Xiaodong Lian, Ce Gao, Xiaoming Sun, Kevin Einkauf, Joshua M Chevalier +26 more